Dr. Marco Marra has been instrumental in bringing genome science to Canada, working across diverse programs of research that have addressed pressing problems and key opportunities of relevance to Canada and Canadians. He has spent much of his career leading teams to conduct large-scale, high-throughput genomics projects with the aim of comprehensive identification of the gentic changes that drive cancer. He believes that better integration of informatics and biology in genome analysis and a strong interface between the lab and the clinic can change outcomes for cancer patients.
Graduate Studies Programs
Graduate Studies in Bioinformatics
The Bioinformatics Graduate Program offers M.Sc. and Ph.D. degrees to students doing research in the field of bioinformatics. This interdisciplinary graduate program, administered by the Faculty of Science at the University of British Columbia and Simon Fraser University, combines training in both biological and computational methodologies.
The strategic objectives of the program are:
- To build on BC’s growing reputation and excellence as a leader in bioinformatics, genomics and population-based approaches to health care
- To integrate bioinformatics with basic biology to further the current research excellence in other life science sectors in the province
Genome Science and Technology Program
This is a multidisciplinary graduate program combining training in genomics, with intensive training in new leading-edge genome science technologies, such as high-throughput techniques that acquire information from DNA sequence (genomics), protein expression and interactions (proteomics), and gene expression patterns (transcriptomics) to exploit information for a better understanding of biology. Designed and taught by leading scientists in Vancouver, B.C., Canada.
Canadian Bioinformatics Workshops
Bioinformatics.ca is the portal to bioinformatics activities in Canada and the home for the Canadian Genetic Disease Network (CGDN)- sponsored Canadian Bioinformatics Workshops series hosted nation-wide.
Interdisciplinary Oncology Program
Studies leading to Master of Science and Doctor of Philosophy degrees are available through the Interdisciplinary Oncology Program in the Faculty of Medicine. The Interdisciplinary Oncology Program offers advanced study and research in a variety of fields relating to oncology. Those fields include: molecular and cellular biology, genetics, biophysics, bioinformatics, pharmaceutical sciences, radiological sciences, immunology, molecular pathology, sociobehavioural studies, epidemiology and health economics.
Dr. Jones’ research program is firmly entrenched in genome science to better understand the complete mutational landscape of cancers. His primary aim is to help uncover the diversity of genetic and genomic events that accrue to give rise to cancers, and which also encourage their evolution and maintain their progression. His laboratory extensively analyzes Next Generation genome and transcriptome data to achieve these goals. Dr.
After completing his PhD in Pharmacology at the University of Alberta in 1998, Dr. Robert Holt conducted his post-doctoral research at the State University of New York in Albany, NY. He joined the faculty at the University of British Columbia in 2003 where he is now a Professor in the Department of Medical Genetics, a Faculty Member of the Genome Science and Technology program, the Interdisciplinary Oncology Graduate Program, the Genetics Graduate Program and the Health Brain Research Centre.
Dr. Angela Brooks-Wilson is a distinguished scientist at Canada’s Michael Smith Genome Sciences Centre. Her laboratory group investigates the genetic basis of cancer susceptibility. One of her primary interests is lymphoid cancers, which include Hodgkin lymphoma, non-Hodgkin lymphoma, chronic lymphocytic leukemia and myeloma. Through collaboration with members of the Cancer Control Research Group at BC Cancer including Dr. John Spinelli, Dr. Brooks-Wilson studies the interaction between genetic susceptibility and environmental triggers in causing lymphoid cancers.
Dr. Gregg Morin received his PhD in Biochemistry from the University of Colorado, Boulder in 1988. Following a postdoctoral fellowship in the Department of Molecular Biophysics and Biochemistry at Yale University and an assistant professorship at the University of California, Davis, Dr. Morin was the Director of the Department of Molecular Biology and Biochemistry at Geron Corporation. In 2004, he joined Canada’s Michael Smith Genome Sciences Centre where he is currently the Head of Proteomics.
After receiving his MD from Queen’s University in Kingston, Ontario and a rotating internship at Lion’s Gate Hospital, North Vancouver, BC, Dr. Karsan practiced medicine in rural BC and the Northwest Territories before working as a volunteer with Médecins Sans Frontières. He then completed his residency in Hematological Pathology at the University of British Columbia (UBC) followed by a Research Fellowship at the University of Washington.
Dr. Hirst is a Senior Scientist and Head of Epigenomics at Canada’s Michael Smith Genome Sciences Centre at BC Cancer, Associate Professor in the Department of Microbiology and Immunology and Associate Director of the Michael Smith Laboratory at the University of British Columbia (UBC).
Dr. Gorski completed a PhD in Biology and Biomedical Sciences at Washington University School of Medicine, St. Louis, MO in 1999. She then conducted postdoctoral studies at the BC Cancer where she utilized genomics approaches to study cell death and cell survival pathways. Dr. Gorski is currently a Distinguished Scientist at Canada’s Michael Smith Genome Sciences Centre at BC Cancer and a Professor in the Department of Molecular Biology and Biochemistry at Simon Fraser University.
Dr. Sadar has served in leadership roles internationally and was the first Canadian to serve as Chair of the USA Army’s Department of Defence’s Programmatic Panel for Prostate Cancer Research. She was President of the Society of Basic Urologic Research (USA) and a board member of education, research, and scientific advisory committees and boards for American and Canadian non-profit societies. Of note, Dr. Sadar was appointed to the Board of Trustees for Canada’s National Museum of Science and Technology by the Minister of Heritage.
Dr. Isabella Tai received her PhD, MD and FRCP(C) designations in Internal Medicine and Gastroenterology from the University of Toronto. She began her academic career as a postdoctoral research fellow in the Department of Cancer Biology at Harvard Medical School. In 2003, she took a faculty position in the Department of Medicine at the University of British Columbia where she is now Associate Professor of Gastroenterology, and became a Senior Scientist at Canada’s Michael Smith Genome Sciences Centre and a Staff Physician at Vancouver Hospital and Health Services.
Dr. Ryan Morin has been studying the genetic nature of lymphoid cancers using genomic methods for more than a decade. During his doctoral training at the University of British Columbia and BC Cancer, he pioneered the use of transcriptome and whole genome sequencing to identify driver mutations in non-Hodgkin lymphomas. Over the course of his training, he published a series of papers describing some of the most common genetic features of diffuse large B-cell (DLBCL) and follicular lymphomas including EZH2, KMT2D, CREBBP and MEF2B.
BC Cancer Foundation is the fundraising partner of BC Cancer, which includes BC Cancer Research. Together with our donors, we are changing cancer outcomes for British Columbians by funding innovative research and personalized treatment and care.