Canada's Michael Smith Genome Sciences Centre offers scientists, researchers and others the opportunity to pursue careers at the forefront of genome science and precision medicine. With close ties to local and national clinical and academic communities—and to scientific collaborators around the world—we offer a rich and diverse research environment. With offices and laboratories located in Vancouver, British Columbia, we work in a city that consistently ranks as one of the best places in the world to live.

Come work with us!

Our commitment to equity, diversity and inclusion

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

COVID-19

All jobs at the GSC are based in Vancouver, British Columbia, Canada. With current COVID-19 conditions and restrictions, for positions with work that can be conducted remotely, some employees and positions will be required to work remotely. Flexible work options may be extended for some positions in the future. Regardless, employees in most roles must be able to work onsite at the GSC, offsite (from home or remotely) or some combination of these.

HEU and HSA union members
Internal applicants please visit internaljobs.phsa.ca to apply online for internal job postings.

Computational Biologist, LIMS

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

 

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: CB LIMS HSA # 107100_P01067_2021_04_16

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority, patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist will participate in the analysis of sequencing data by developing, refining and adapting bioinformatics tools for a high-throughput processing pipeline.  The Computational Biologist will also participate in the development and maintenance of the production databases, which provide tracking of all of the laboratory and bioinformatics analysis pipelines at the GSC.  Additionally, the Computational Biologist will assist in the packaging and distribution of developed tools and analysis results to the scientific community, and will be contributing to the preparation of scientific publications. 

Duties

  • Assists in the development and maintains the core sequence analysis pipelines at GSC, including but not limited to:
    • QC of sequencing data;
    • Alignment of sequenced reads;
    • Formatting and manipulation of alignment files for use by downstream pipelines (e.g. merging, reheadering);
    • Dissemination of data to collaborators;
    • New analyses pipelines as required.
  • Assists in the development and maintains GSC laboratory, quality and analysis databases, including:
    • Routine database integrity checks and database maintenance;
    • Development of views and interfaces for data entry;
    • Development of reports for internal users and collaborators;
    • Investigation of new frameworks and designing new schemas and tables.
  • Communicates with stakeholders in the lab, on analysis teams, and with external collaborators to understand and document requirements for development and to respond to questions about collaborator data and data quality.
  • Works with upstream and lab teams generating data to be housed in the database, and with downstream users of the databases to meet requirements, and responds to internal requests for query and API support.
  • Participates in the development and maintains ETL pipelines between GSC production databases.
  • Manages the storage and compression of over 5Pb of internally generated sequencing data as well as the download and storage of external data.
  • Works closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security, and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements.
  • Tests and validates new data analysis software for analyses such as alignment, duplicate marking and merging.
  • Participates in code walk-throughs and reviews of solutions.
  • Participates in the design and builds database solutions, taking performance into consideration.
  • Coordinates production problem resolution for assigned applications, including working with other technical teams.
  • Produces thorough but concise written documentation of database tables, applications, validations, SOPs, and other processes and procedures as required.

Performs other related duties as required.

Eligibility

Education, Training and Experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components. 
  • Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

  • Demonstrated expertise in database programming and database design.
  • Demonstrated ability in Python.
  • Experience designing and/or maintaining a relational database including knowledge of SQL or PostgreSQL, and with ORMs.
  • Experience with REST API development.
  • Experience with front-end web development (AngularJS, React).
  • Functional knowledge of distributed version control systems, such as GIT.
  • Experience developing software as part of a team, familiarity with Agile development and ticketing systems.
  • Comfortable working in an Unix environment, including experience with shell scripting and common command-line tools.
  • Excellent verbal and written communication skills.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a part-time temporary basis. This restriction would be re-evaluated upon re-contracting.

Computational Biologist, Variant Databases

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: CBVD_HSA Req # 107052_P01069_2021_04_16

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority, patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist will participate in the ongoing design, implementation and maintenance of the full stack (database backend as well as API, web visualization and frontend) of the database applications, housing genomic and clinical research data. The Computational Biologist will also participate in several high-profile national data sharing efforts in which the databases play a central role.

Duties

  • Participates in maintaining, designing and developing the GSC analysis and variant databases, including:
    • Checking data integrity and loading new data into existing tables;
    • Working with external data sources for genomic and sample metadata;
    • Design and implementation of new schemas and tables to house new data types;
  • API and front-end web application development.
  • Works with upstream bioinformatics and lab teams generating data to be housed in the database and responding to internal requests for query and API support.
  • Collaborates with other sequencing sites in Canada and internationally to share data and define best practices for data sharing.
  • Works closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security, and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements.
  • Works with clinical and research teams to develop web interfaces and patient reports for use in the clinic and within the research community.
  • Performs literature searches, testing and validation of new data analysis software, prepares presentations at scientific conferences.
  • Participates in code walk-throughs and reviews of solutions.
  • Participates in the design and build of database and software solutions taking performance into consideration.
  • Coordinates production problem resolution for assigned applications, including working with other technical teams.
  • Evaluates third-party software and incorporates new systems into legacy systems.
  • Produces thorough but concise written documentation of software, validations, SOPs, and other processes and procedures as required.

Qualifications

Education, Training and Experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components. 
  • Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders. 

Skills and Abilities

  • Demonstrated expertise in database programming and database design.
  • Demonstrated ability in Python and/or Javascript (NodeJS).
  • Experience designing and/or maintaining a relational database including knowledge of SQL or PostgreSQL, and with ORMs.
  • Familiarity with non-relational databases such as Hadoop or graph databases.
  • Experience with REST API development.
  • Experience with front-end web development (React, AngularJS).
  • Functional knowledge of distributed version control systems, such as GIT.
  • Experience developing software as part of a team, familiarity with Agile development and ticketing systems.
  • Comfortable working in a UNIX environment, including experience with shell scripting and common command-line tools.
  • Excellent verbal and written communication skills.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a part-time temporary basis. This restriction would be re-evaluated upon re-contracting.

Research Assistant 2, Proteomics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RA 2_R00004_2021_04_14

Working as part of the proteomics core facility, the individual will assist in the day-to-day operation of the core. This individual will operate and maintain the hardware and software present in the core facility. In addition, this individual will work together with the Facility Manager and users to plan, coordinate, conduct and report on assigned research projects. Key responsibilities of the individual will include communication with colleagues and collaborators for project planning and results dissemination, preparation of samples for proteomic and/or metabolomic analysis, as well as basic mass spectrometry data analysis.

Key accountabilities include:

  • Performs a variety of established technical procedures according to written protocols.
  • Performs experiments by following established laboratory procedures according to written protocols.
  • Records results, including computer data entry.
  • Provides input regarding modification of procedures as requested by the Department Head, Principal Investigator, or designate.
  • Maintains and stores cell lines and primary cultures.
  • Maintains and stores test materials and products.
  • Maintains inventory of laboratory supplies and equipment.
  • May demonstrate work methods or procedures to less experienced assistants as designated.

Additional responsibilities include:

  • Liaising with collaborators to coordinate sample submission
  • Preparing samples for proteomic analysis
  • Analyzing the samples on facility instrumentation
  • Operating and maintaining facility instrumentation
  • Performing initial mass spectrometry data analysis
  • Maintaining logs of samples analyzed and instrument use
  • Communicating results to lab members as well as collaborators

Eligibility

The successful candidate is expected to have a level of education, training, and experience equivalent to graduation from a recognized technical program in an appropriate discipline or similar; plus two (2) years of recent related experience in a research laboratory.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a part-time temporary basis. This restriction would be re-evaluated upon re-contracting.

Knowledge Translation Coordinator

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Are you an excellent communicator with passion for science and technology?

Do you have a knack for creative writing and design, with an eye on detail?

Can you translate technical language and jargon for non-scientific audiences?

The GSC is looking to add a Knowledge Translation Coordinator to its Knowledge Translation team. Reporting to the Head of Knowledge Translation, this position will support the development of materials, activities and events that help communicate the GSC’s research projects, collaborations and innovations to a variety of audiences, both scientifically literate and not.

Main Responsibilities

  • Coordinate the development of digital and print materials as well as activities and events in collaboration with the Knowledge Translation team, scientists, trainees, project managers and other staff members.
  • Write, edit, design and proofread scientific and technical publications, as well as copy for non-scientific audiences including research summaries, web and social media content, multimedia, etc. 
  • Recommend strategies and develop plans, tools and practices for reaching new audiences in collaboration with the Head of KT and other project and program leaders.
  • Monitor status and progress for KT activities to ensure quality and timeliness; provides relevant information and project progress reports.
  • Propose and create compelling content (including design materials using Adobe Suite) for the web and social media related to the GSC’s research projects and programs, and technology platforms and services.
  • Identify and evaluate objectives and project milestones; flag discrepancies for the attention for the Head of KT.
  • Work with client relationship management software (Salesforce) to ensure timely and professional communications with stakeholders about research projects and scientific collaborations.
  • Other duties as required. 

Qualifications

A level of education, training and experience equivalent to completion of a Bachelor’s of Science (a Master’s or PhD is an asset) in biology, genetics or a related field from a recognized university plus a minimum of five (5) years of recent related experience in an academic or industry research setting (experience in the biotechnology sector is an asset).

Skills and Knowledge

  • Demonstrated experience and expertise in science communication, including the development of plans and strategies, print and digital materials, and event organization, for research, education, business, marketing, promotion and/or knowledge translation/transfer/mobilization/exchange purposes.
  • Excellent command of the English language, and exceptional communications skills including in speech and writing; fluency with other languages is an asset.
  • Experience and confidence in editing, proofreading and/or providing review and critique on the written work of both junior and senior staff members, including scientists and principal investigators.
  • Understanding of Canadian scientific and research processes, including ethics, funding and peer-reviewed publication processes, policies and procedures.
  • Fundamental computer literacy is mandatory, including familiarity with the Microsoft suite of products (Word, Excel, PowerPoint, Outlook); experience with the Adobe Suite of products (Photoshop, Illustrator, InDesign) and/or with Client Relationship Management software (Salesforce) for business development purposes are very strong assets.
  • Demonstrated organizational, analytical and critical thinking skills, including the ability to manage multiple projects and activities within a fast-paced environment under pressure and to do so independently or cooperatively, optimistically and respectfully in a diverse and inclusive team environment.

Apply

Please submit a cover letter and resume to bcgscjobs@bcgsc.ca

The position will remain open until filled.

We thank all applicants; however, only those selected for the next step will be contacted.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority. 

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.

Research Programmer

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RP POG_R00008_2021_03_16

Canada’s Michael Smith Genome Science Centre of BC Cancer is looking for an enthusiastic and self-motivated Research Programmer to work on a federated genome data sharing project based on the Global Alliance for Genomics and Health framework. The position is within Dr. Steven Jones’ group, therefore the successful candidate will have the opportunity to get insights on Personalized OncoGenomics (POG) program and other precision medicine initiatives. This requires a combination of interest in DNA technology and a strong background in software development.

Eligibility

The successful candidate will have the following qualifications:

  • Undergraduate degree in computer science, software engineering or any quantitative science field related to genomics or cancer biology.
  • Experience in front and/or back end development as well as solid programming skills in Python is a must.
  • Experience with Flask and Javascript or other web framework would be particularly useful.
  • Basic understanding of DNA technology or previous work experience with genetic data is a plus, but not required for the position.
  • The position requires working with a wide variety of researchers, software developers and clinicians, thus excellent communication skills are essential.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a part-time temporary basis. This restriction would be re-evaluated upon re-contracting.

Research Assistant 2

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: RA2-R0004-2021-03-10

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

Incumbents have directly related laboratory experience and familiarity with specific research programs and methodologies of the hiring laboratory.  They work under supervision and perform experiments by following established laboratory procedures.  They report to the Department Head, Principal Investigator, or designate, with duties including: 

  • Performs a variety of established technical procedures according to written protocols.
  • Performs experiments by following established laboratory procedures according to written protocols.
  • Records results, including computer data entry.
  • Provides input regarding modification of procedures as requested by the Department Head, Principal Investigator, or designate.
  • Maintains and stores cell lines and primary cultures.
  • Maintains and stores test materials and products.
  • Maintains inventory of laboratory supplies and equipment.
  • May demonstrate work methods or procedures to less experienced assistants as designated.

Eligibility

A level of education, training, and experience equivalent to graduation from a recognized Bachelor’s program in an appropriate discipline (e.g., Bachelor of Science) plus two (2) years of recent related experience in a research laboratory. A familiarity with mammalian cell culture techniques, flow cytometry/FACS and library construction for DNA sequencing will be considered essential assets.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a part-time temporary basis. This restriction would be re-evaluated upon re-contracting.

Post-Doctoral Fellow, Immunogenomics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: PDF-01553-2021-03-08

The GSC is seeking a Post-Doctoral Fellow to conduct scientific research in the areas of immunogenomics, T cell biology, and genetically engineered cell therapy, with a special focus on discovery and characterization of therapeutic T cell receptors using novel high-throughput screening approaches.

Experience in recombinant DNA and gene editing technologies, gene therapy vectors, mammalian cell culture (including primary T cell culture), flow cytometry/FACS, and cell-based assays (such as ELISPOT) is desired. Familiarity with 2nd and 3rd generation DNA sequencing platforms (including single-cell sequencing platforms) will be an asset.

Reporting to Dr. Robert Holt, Distinguished Scientist & Co-Director of the BC Cancer Immunotherapy Program, your typical duties will include the following:
•    Contributing to the design and construction of cell libraries for high-throughput screening experiments.
•    Performing high-throughput T cell receptor profiling screens.
•    Characterization and validation of novel discoveries stemming from high-throughput screening studies. 
•    Reporting research methods and results in meetings, seminars and conferences.
•    Contributing to and/or leading scientific publications and funding proposals

Eligibility

The ideal candidate should possess a PhD degree and recent experience in immunology, genomics, cancer biology, cell biology or a related discipline. A strong publication record and track record of successful funding applications are highly desirable. This position is funded by the Michael Smith Foundation for Health Research Innovation to Commercialization program and, as such, an interest or aptitude for technology development and/or industrial applications would be a valuable asset.  

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a part-time temporary basis. This restriction would be re-evaluated upon re-contracting.

Research Associate

Job Reference Number: RA-R00006-2021-02-22

About us

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC

As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on part-time temporary basis.  This restriction would be re-evaluated upon re-contracting*


Role Summary

Canada’s Michael Smith Genome Sciences (GSC) at BC Cancer is looking for a Research Associate to work within the Technology Development Group (Biochemistry), to assess or develop new technologies that will continue to propel the GSC forward at the leading edge of science. Such work may, for example, include  the evaluation of leading technologies that emerge in the marketplace, and the development of novel genomic technologies, such as those that support large-scale provincial and national projects, including BC Cancer’s Personalized OncoGenomics program, the Terry Fox Research Institute (TFRI) PROFYLE project and the TFRI-led Marathon of Hope Cancer Centres Network—a major federal initiative co-developed with GSC involvement to accelerate the adoption of cancer precision medicine in Canada.

Working in the Technology Development Group (Biochemistry), under the direction of the Director of the GSC and directly reporting to the Group Leader, the successful applicant will help test, devise, develop and implement ‘omic technologies in the laboratory, as well as analyze, propose and present innovative workflows to increase the efficiency of genomics activities. We seek an engaged, enthusiastic team player with excellent bench and computational skills, a demonstrated ability to design and conduct well-controlled experiments, and a passion for genome science.

Main Responsibilities

  • Test and/or develop novel and efficient methods to enable the scale and throughput the GSC requires to operate at the leading edge of its fields.
  • Perform pilot or “custom” experiments, which may require e.g. following protocols published in the literature, or modifying an existing production protocol to meet specific project needs.
  • Provide support to production groups, such as drafting Standard Operating Procedures, training production staff, and troubleshooting exercises.
  • Summarize and analyze data and results, and formally present findings in meetings and discussions, including at local, national and international meetings Interact closely and in support of group leaders and their teams to address priorities and project timelines          
  • Co-author scientific manuscripts related to research and technology findings.
  • Co-develop research grant applications.
  • Contribute to quarterly and annual reports for research projects.
  • Perform other related duties as required.

Qualifications

Education and experience

  • PhD in a life sciences-related discipline, or MSc with 3 years demonstrated experience in genomics, or molecular biology. Knowledge or experience in e.g. high-throughput, large-scale DNA sequencing and genomic library production would be a plus.

Skills and abilities

  • Molecular Biology.
  • Knowledge and experience in laboratory automation.
  • Knowledge of science and technologies pertaining to cancer genomics.
  • Knowledge and experience in operating a laboratory information management system (LIMS) is advantageous.
  • Experience with formal quality assurance systems is advantageous.
  • Experience with high-throughput sequencing is desirable.
  • Experience in a supervisory role is an asset.  

To Apply

Please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca with the subject title, Research Associate Position RA-R00006-2021-02-22.

While we are looking to fill this position as soon as possible, please note that this position will remain open until filled.

We thank all applicants; however, only those selected for the next step will be contacted

Computer Systems Specialist

Job Code: CSS HEU Req # 104022

About us

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC

As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on part-time temporary basis.  This restriction would be re-evaluated upon re-contracting*


Role Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computer Systems Specialist provides high-end technical support for the GSC information technology infrastructure.  This infrastructure includes the data servers, data network, and client workstations, as well as the website.  Duties include establishing technical standards, designing infrastructure architecture, installing, configuring and upgrading infrastructure components, monitoring infrastructure security and performance, and proactively planning infrastructure enhancements.

This position is unionized and falls under the HEU collective agreement
http://www.heabc.bc.ca/public/CAs/FBA/FBA_CA_2019-2022.pdf

Duties

  • Maintains the enterprise class storage systems.
  • Manages the data backup and recovery procedures.
  • Installs, configures, modifies and tests computer hardware used as servers on the GSC network.
  • Installs, configures, and upgrades server software.
  • Designs and implements the GSC network infrastructure, including the design of network topology and the selection and installation of network components.
  • Monitors the security of the information technology infrastructure and its components, including firewalls.
  • Prepares and communicates policies and procedures on security.
  • Develops configuration standards and implementation procedures for network peripherals such as client workstations and network printers.
  • Maintains website hardware and runs webserver software.
  • Creates and maintains mailing groups.
  • Codes, modifies, tests and maintains programs to meet user requirements.
  • Develops GSC wide backup and recovery procedures.
  • Monitors and reports on the performance of all infrastructure components, and responds to and resolves any issues regarding performance.
  • Prepares plans for proactive infrastructure upgrades, including evidence-based reporting on the rationale for such upgrades.
  • Resolves user issues on the technical infrastructure.
  • Provides expert advice on technical issues.
  • Assists with strategic planning on GSC information technology infrastructure, including data, voice and video.
  • Consults with external contacts, including vendors and external partners, on issues regarding technical infrastructure.
  • Performs related duties as required.

Qualifications

Education, Training and Experience

  • Completion of Grade 12, plus graduation from a recognized two-year systems technology diploma plus three (3) years of recent related experience, which includes experience in:
    1. Enterprise class storage systems
    2. Backup and recovery procedures to disk and tape
    3. Client/server architecture.
    4. Multi-user networked environment.
    5. Personal computers.

            Or an equivalent combination of education, training and experience.

Skills and Abilities

  • Ability to type.
  • Ability to communicate and deal effectively with all levels of staff both verbally and in writing.
  • Physical ability to carry out the duties of the position.
  • Ability to organize work.
  • Ability to operate related equipment.

To Apply

Use the subject title:  CSS HEU Req # 104022 Computer Systems Specialist

For internal applicants please visit internaljobs.phsa.ca to apply online.  

For external applicants, please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca

Lab Operations Safety Coordinator

Job Reference No.:  SC-R00022-2021-02-05

About us

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC

As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on part-time temporary basis.  This restriction would be re-evaluated upon re-contracting*


Role Summary

The activities required in this role are conducted in accordance with the strategic directions of the Provincial Health Services Authority (PHSA), BC Cancer (BCC), the BC Cancer Research Centre (BCCRC), and the Genome Sciences Centre (GSC). Reporting to the Lab Operations Team Leader, the Safety Coordinator is the GSC’s primary safety liaison to the BCCRC’s Safety Office and its constituent departments, and is responsible for coordinating various safety aspects of the GSC’s Production and clinical DNA sequencing operations. This includes both dry and wet lab personnel in multiple buildings. To accomplish this, the Safety Coordinator interacts with virtually all department personnel to ensure that legal, accreditation, and functional safety requirements are met, and that a participatory culture of safety engagement is maintained.

Key Responsibilities

  • Ensures compliance with existing CAP (College of American Pathologist), ISO27001 (International Organization for Standardization), and DAP (Diagnostic Accreditation Program) safety regulations; implements policies and procedures to ensure successful compliance; communicates pertinent information to stakeholders; participates in regular audits by accreditation agencies; assists in developing policies and procedures for prospective accreditations.
  • Works with the Quality Systems group to regularly review and update the departmental safety manual; communicates changes in safety policies to relevant personnel.
  • Engages in regular safety education activities to re-enforce policies and procedures to department personnel; works with Knowledge Translation and Communication team to maintain regular content in the GSC newsletter; conducts regular safety education on relevant topics; coordinates regular seminars by external groups to provide professional education.
  • Chairs the Echelon Joint Occupational Health & Safety Committee (EJOHSC), and represents the GSC at the CRC JOHSC meeting; carries out action items and activities prescribed by the JOHS committees; is the primary safety liaison to various operational meetings.
  • High degree of familiarity with WorkSafeBC and WHMIS regulations and knowledgeably applies them to both dry and wet lab space; regularly audits compliance; educates personnel on changes to regulations; provides tools and guidance to personnel to facilitate compliance.
  • Participates in and documents both casual and formal safety inspections at all GSC sites; documents safety concerns, consults with stakeholders and implements corrective actions.
  • Works with department personnel to address ergonomic issues; guides personnel through a complex ergonomics process; works with PHSA Ergonomists to devise, implement and monitor corrective actions.
  • Manages all safety-related training requirements; oversees compliance in maintaining certification; ensures that all safety training is documented promptly and accurately; communicates with personnel who are delinquent with safety training.
  • Oversees hazardous waste disposal at all GSC sites; works with wet lab staff to determine safe disposal procedures; manages administrative aspects of invoicing and collection; maintains records of service; ensures compliance with accreditation and legal requirements.
  • Conducts incident and near-miss investigations; guides personnel through the reporting process, and implements corrective actions; consults with stakeholders and JOHS committees regarding incidents.
  • Monitors wet labs for chemical inventories and compatibilities; performs regular analyses and chemical risk assessments; maintains SDS database and ensures availability of SDS to wet lab staff.
  • Works collaboratively with the Lab Operations and Quality Systems teams to create, implement, and document safety procedures and SOPs.
  • Keeps apprised of proposed and actual changes to laws, regulations, and policies put forward by the Public Health Agency of Canada (PHAC), WorkSafeBC, BCCRC, CAP, and DAP; engages GSC stakeholders on these changes; works to implement changes as required.
  • Attends external conferences, working groups, and meetings to represent the GSC; leads team participation in safety-related competitions; maintains professional relationships in order to guide best practices and share information.
  • Provides and documents safety orientations for incoming staff members.
  • Oversees the First Aid program.
  • Participates in emergency on-call rotations.
  • Manages the departmental Incident Management Team (IMT); organizes meetings; maintains emergency response documentation; conducts practice drills.
  • Performs other related duties as assigned.

Qualifications

  • A level of education, training, and experience equivalent to completion of a Bachelor of Science from a recognized college, plus a minimum of 3 (three) years of recent related experience in a research role.
  • Experience in laboratory safety management is required, with demonstrated familiarity with PHAC and WorkSafeBC regulations. Applicants should have strong capabilities in Microsoft Access and Excel, with a high aptitude for self-learning of new technical skills.  Excellent organizational and communication skills are required.
  • Relevant experience in a clinically- or ISO-accredited environment is desirable, but not required.

To Apply

Please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca with the subject title:   Lab Operations Safety Coordinator SC-R00022-2021-02-05

Project Manager

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC. But it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers and clinicians. We look for people who share our core values—science, timeliness and respect—to join us in our mission to provide genomics, bioinformatics and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity is essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely.  This restriction would be re-evaluated upon re-contracting*


Role Summary

The Genome Sciences Centre is seeking a Projects Manager. This role is for a Manager of research projects, grants and platforms in a research environment.

Reporting to the Head, Project Management or Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones. Projects will involve personalized oncogenomics, collaborative services management, or other cancer genomics research.

Key Responsibilities

  • establishing budgets for research projects, grants, collaborations and core activities
  • assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
  • monitoring budgets and expenditures
  • establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives, which may include, meeting coordination and follow-up, coordination of case reviews
  • maintain accurate information on sample status, including sample and associated metadata acquisition, processing, stakeholder reporting
  • recommending strategies for improving projects management methods and processes
  • liaising with grant/core funding agencies
  • interacting directly with research collaborators or clinical study teamsas required

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will experience in academic scientific research, clinical trials research, the biotech or software industries. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at level Research Project Coordinator, which is equivalent to that described above.

To Apply

Please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca

Please note that this position will remain open until filled.

We thank all applicants; however, only those selected for the next step will be contacted.

Assistant Bioinformatics Coordinator

Job Code: ABC HSA Req # 103782

About us

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC

As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on part-time temporary basis.  This restriction would be re-evaluated upon re-contracting*


Job Summary

This position is unionized and falls under the HSA collective agreement

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Assistant Bioinformatics Coordinator provides supervisory and technical support to the Bioinformatics group of the GSC, ensuring that the day-to-day activities of a large scale, high throughput facility meet research, data analysis throughput and software development objectives. 

Duties

  • Assists the Bioinformatics Coordinator in the day to day activities of the Bioinformatics group by performing duties such as providing input on quantity and quality of work, making recommendations for improvements, workflow and procedures.
  • Coordinates projects of the Bioinformatics group by performing duties such as chairing project-specific meetings and provides project status reports to the Bioinformatics Coordinator, with suggestions towards any required improvement of project management, task allocation and overall process.
  • Develops and implements assays to monitor project progress and measure project accomplishments to ensure that appropriate project focus is maintained and to provide feedback to staff.
  • Provides supervisory support to the Bioinformatics group by performing duties such as:
    • Orientating new staff.
    • Providing input to the Bioinformatics Coordinator on training requirements.
    • Providing input to the Production Coordinator on the establishment of clear definitions of responsibility for employees.
    • Assigning workload assignments and establishing work schedules.
    • Reviewing and establishing work priorities and adjusting work schedules to ensure priorities are met.
    • Completing performance reviews and addressing performance issues in conjunction with the Production Coordinator.
  • Participates in the recruitment of staff through methods such as interviewing internal and external applicants and forwards hiring recommendations.
  • Participates in the development and implementation of quality improvement programs to ensure services are provided in the most efficient and effective way by performing duties such as:
    • Monitoring quality and quantity of service and information provided by the bioinformatics group and identifying areas for change and/or improvement.
    • Generating test metrics to evaluate progress of research programs.
  • Assesses practical needs for identified research direction of the GSC in conjunction with the Bioinformatics Coordinator and Analysis Group Leader.
  • Participates in a variety of meetings by performing duties such as providing and/or receiving information and contributing to decision making.
  • Participates, in conjunction with the Bioinformatics Coordinator, in determining the computer infrastructure necessary for successful completion of projects and ensured viability of research programs by performing duties such as providing input and recommendations regarding purchasing decisions related to hardware, software and related items for the Bioinformatics platform.
  • Interprets statistical analyses and makes recommendations for review including preparing reports on statistical findings for publication and presentation in HTML format or as advised.
  • Conducts feasibility studies for computerization by performing duties such as determining user requirements, examining and identifying problems with existing systems and recommending modifications to and/or new systems; provides details of estimated implementation costs including associated staffing requirements.
  • Performs technical functions related to the bioinformatic functions of the GSC.
  • Performs other related duties as required.

Qualifications

Education, Training and Experience

Graduation from a recognized Bachelor’s program in a related discipline such as Biochemistry, Genetics, Computer Science, Electrical Engineering or Physics.  A minimum of four (4) years of recent related experience including experience in computer programming and quantitative data analysis, handling biological sequence and/or mapping data, database development and data storage schemas or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

  • Experience with computer operating systems such as Linux, UNIX.
  • Demonstrated ability to work with software such as C, C++, Perl , Matlab, MySQL.
  • Demonstrated ability to accept responsibility and work independently.
  • Demonstrated ability to work effectively with others in a team environment.
  • Demonstrated ability to supervise staff and schedule work.
  • Excellent organizational, leadership interpersonal and communication skills.
  • Physical ability to perform the duties of the job.

To Apply

Please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca

Manager, Systems

About us

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC

As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on part-time temporary basis.  This restriction would be re-evaluated upon re-contracting*


Role Summary

Canada’s Michael Smith Genome Science (the “GSC”) at BC Cancer is looking for a Manager, Systems, responsible for developing, maintaining, and supporting the IT infrastructure of the GSC.

Under the direction of the Head of Bioinformatics, the Manager, Systems develops a vision for the IT infrastructure capable of supporting the future research direction and production requirements of the GSC.

The Manager, Systems ensures the confidentiality, integrity and availability of data within the department and organization.

 If you have experience leading teams, managing multiple projects at the same time, and you enjoy solving problems and working with multiple stakeholders, please read on.

 Key accountabilities

  • Liaise with members of senior management to solicit requirements and report progress of IT
  • Manage high-level planning for informatics research and laboratory production requirements
  • Manage the design and development of IT systems and projects
  • Provide leadership, coaching and direction to the Systems team including coop students
  • Coordinate and prioritize project plans and tasks
  • Address and resolve reported project roadblocks, and develop procedures to reduce these
  • Manage support issues from all staff and maintain systems to ensure that support issues are handled and prioritized accordingly
  • Develop service level agreements within the organization
  • Develop and manage process for new releases and changes to the production environment
  • Manage software license compliance, and participate in regular audits
  • Responsible for data security, storage and archiving as per business requirements
  • Develop and enforce technical information system standards
  • Design and develop implementation of information systems policies and training material

Qualifications

  • Undergraduate degree from a recognized institution in Computer Science, Electrical Engineering and/or Life Sciences or related field or a combination of relevant education and work  experience
  • A minimum of 7 years of relevant experience working in an IT department or similar environment
  • A minimum of 2 years’ experience managing and directing a systems team
  • Knowledge of softwares such as Slurm, Atlassian, Linux (Centos, Ubuntu), Windows10,  Macintosh, Office, LDAP, AD, Exchange an asset
  • Experience working with network such as Brocade and Barracuda an asset
  • Knowledge of audit process, including ISO an asset
  • Demonstrated ability to work independently and collaboratively as appropriate
  • Excellent organizational and leadership skills. Ability to coach and motivate staff
  • Excellent oral, written and interpersonal communication skills
  • Ability to use audience appropriate communication and language to present information and convey concepts
  • Ability to achieve results in a fast-paced research environment

To Apply

Please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca

While we are looking to fill this position as soon as possible, please note that this position will remain open until filled.

We thank all applicants; however, only those selected for the next step will be contacted.

Postdoctoral Fellow, Gastrointestinal Cancers

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position may require working remotely.  This restriction would be re-evaluated upon re-contracting*


Role Summary

A Post-doctoral position is available immediately for a highly motivated recent PhD or MD/PhD graduate to join a dynamic translational research group, headed by Dr. Isabella Tai, Associate Professor in the Division of Gastroenterology, University of British Columbia and Senior Scientist at Canada's Michael Smith Genome Sciences Centre at BC Cancer.

Current projects in the laboratory revolve around improving our understanding of the mechanisms involved in the development of chemotherapy resistance and metastasis in gastrointestinal cancers (colorectal, gastric, liver and biliary cancers). The goal is to develop either novel therapeutic targets for GI cancer treatment or novel screening tools for diagnosis. We continue to use the latest genomics (including single cell sequencing), proteomics and bioinformatic approaches to identify potential targets or markers for this purpose. Learn more about research projects in the Tai lab here.

Eligibility

Interested individuals with a recent PhD or MD/PhD and strong publication records and excellent academic credentials are encouraged to apply.  Experience in molecular biology, cell biology, tissue culture and animal tumor models, is preferable.  Experience in bioinformatics is an asset.

Duration

Three years (possibility of extension).

To Apply

Please submit a cover letter, curriculum vitae, and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience, long-term career goals and an indication of the desired length of postdoctoral position.

Please email your application to bcgscjobs@bcgsc.ca

Research Programmer

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely.  This restriction would be re-evaluated upon re-contracting*


Role Summary

The Karsan lab team at Canada’s Michael Smith Genome Sciences Centre (GSC) is seeking a research programmer to join a Genome British Columbia software automation project. The team will be working with the Karsan lab, which is responsible for developing high-throughput, clinically accredited pipelines to analyse sequenced data from genomic assays for individualized patient management of cancer. We seek candidates with strong Python software and programming skills to automate and improve existing pipelines and potentially incorporate third-party software into the system.

The role is ideally suited for a creative individual with a strong interest in software development and testing, data analysis, and automation within a high throughput academic setting.

Key responsibilities

  • Design, plan, and implement automated bioinformatics pipelines to meet the objectives of the project
  • Work with other project team members to develop and test code, and implement software
  • Evaluate third-party software and incorporate new systems into legacy systems
  • Produce thorough but concise written documentation of algorithms, validations, SOPs, and other processes and procedures as required

Qualifications

Education, training and experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science. A Master’s degree in a relevant field would be a strong asset. 
  • Two (2) years of recent related experience or an equivalent combination of education, training, and experience acceptable to the project lead.

Core Skills and Abilities 

  • Expertise with Python 3.X and able to provide links to code samples via GitHub or another open repository
  • Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
  • Familiarity with molecular and cellular biology
  • Excellent verbal and written communication skills.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets

  • Familiarity in statistical analysis using modern computational tools.  Experience with any relevant tools will be considered, but R and Python are preferred
  • Familiarity with the development, testing, and maintenance of relational databases
  • Familiarity in next-generation sequencing
  • Experience with software testing
  • Experience with Agile software practices
  • Functional knowledge of distributed version control systems, such as SVN or GIT

To Apply

Please email your cover letter and resume to bcgscjobs@bcgsc.ca

Please note that this position will remain posted until filled.

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