Canada's Michael Smith Genome Sciences Centre offers scientists, researchers and others the opportunity to pursue careers at the forefront of genome science and precision medicine. With close ties to local and national clinical and academic communities—and to scientific collaborators around the world—we offer a rich and diverse research environment. With offices and laboratories located in Vancouver, British Columbia, we work in a city that consistently ranks as one of the best places in the world to live.

Come work with us!

Our commitment to equity, diversity and inclusion

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

COVID-19

All jobs at the GSC are based in Vancouver, British Columbia, Canada. With current COVID-19 conditions and restrictions, for positions with work that can be conducted remotely, some employees and positions will be required to work remotely. Flexible work options may be extended for some positions in the future. Regardless, employees in most roles must be able to work onsite at the GSC, offsite (from home or remotely) or some combination of these.

HEU and HSA union members
Internal applicants please visit internaljobs.phsa.ca to apply online for internal job postings.

Research Programmer – Data Scientist

Job Reference No. RP_R00008_Karsan Lab_2022_05_31

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. Dr. Aly Karsan and the Karsan Lab team are seeking a Research Programmer to join a Marathon of Hope Cancer Centre research project.  

The successful applicant will be working with other research programmers in the Karsan lab to develop data analysis pipelines for various next-generation sequencing (NGS) data such as—but not limited to—scRNA-Seq, targeted sequencing, ATAC-Seq, and BS-Seq. We seek candidates with strong analytical and programming skills to research, develop, and improve our research pipelines for studying cancer evolution. The role is ideally suited to detail-oriented individuals with a strong interest in data analysis, research, and scientific programming within a high throughput academic setting. 

By working within the Karasn Lab at the GSC, you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada. The Karsan lab has a history of strong publications and a diverse computational biology core for knowledge sharing, collaboration, and support. 

This is a non-union position funded by a BC Cancer Foundation Grant. We offer a competitive salary, excellent benefits and significant career development opportunities. Remote applicants are encouraged to apply.

Responsibilities 

  • Design and implement bioinformatic data pipelines to meet objectives of the project.
  • Work with other project team members to develop and test code and implement analysis.
  • Evaluate and incorporate third-party software into pipelines.
  • Produce thorough but concise written documentation of experiments, algorithms, validations and other procedures as required.

Qualifications

  • Graduation from a recognized Bachelor of Science Program in Computer Science or relevant program. A Master’s degree in a relevant field would be a strong asset. 
  • Two (2) years of recent related experience or an equivalent combination of education, training and experience.

Core Skills and Abilities: 

  • Expertise with scientific programming and ablility to provide links to code samples via GitHub.
  • Familiarity with molecular and cellular biology.
  • Excellent verbal and written communication skills.
  • Demonstrated ability to interpret results.
  • Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools.
  • Established ability to efficiently organize work assignments and establish priorities.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets:

  • Familiarity in statistical analysis using modern computational tools (experience with any relevant tools will be considered, but R and Python are preferred).
  • Familiarity in next-generation sequencing datasets.
  • Understanding of cancer biology.
  • Functional knowledge of distributed version control systems, such as SVN or GIT.

How to Apply

Applicants should submit: a CV; a one-page cover letter highlighting relevant research experience, interests and goals; and the names and contact details of three (3) references.

Please send your application to bcgscjobs@bcgsc.ca and include the job reference number in the subject line of the email. While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

We believe that equity and diversity are essential for the advancement of human knowledge and science.  We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Postdoctoral Fellow – Bioinformatics

Job Reference Number: PDF_01553_Steif Lab_2022_05_16

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Postdoctoral Fellow to join Dr. Adi Steif’s computational biology group.

The successful incumbent will lead the analysis of single cell data from a novel instrument, under development in collaboration with the groups of Dr. Karen Cheung (Biomedical Engineering) and Dr. Marco Marra (GSC / Medical Genetics). Funded by Genome BC, the project aims to improve the scalability and accuracy of cell isolation, in order to investigate tumour cellular diversity and evolution.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within the Steif Lab at the GSC, you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now!

Responsibilities

Working in a multidisciplinary team, the postdoctoral fellow will contribute to experimental design and protocol optimization. They will develop scalable analytical workflows in a high-performance computing environment to characterize the genomes and transcriptomes of cancer cells. This is a one-year term appointment, with potential for renewal.

  • Regular review of the scientific literature
  • Contribute to experimental design and planning
  • Data preprocessing and quality control
  • Data analysis, visualization, and biological interpretation
  • Develop and maintain well-documented code
  • Regularly update Dr. Steif and key collaborators on the status of projects
  • Participate in and present research updates at lab meetings and team meetings
  • Contribute to scientific writing, including the preparation of research manuscripts and grant applications
  • May be involved in recruitment, management, and supervision of trainees

Qualifications

  • A PhD in bioinformatics, biostatistics, computer science or related discipline
  • At least 3 years of research experience in computational biology, with a record of first-author publication
  • Experience in genomics and the analysis of sequencing data
  • Knowledge of molecular biology and genetics
  • Experience in cancer research is an asset
  • Programming fluency in Python or R
  • Experience working in a Unix/Linux environment
  • Critical thinking and attention to detail
  • Excellent verbal, written and interpersonal communication skills
  • Ability to work independently and in a collaborative interdisciplinary team
  • A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines

How to Apply

Applicants should submit: a CV; a one-page cover letter highlighting relevant research experience, interests and goals; and the names and contact details of 3 references. 

Please send your application to bcgscjobs@bcgsc.ca and include the job reference number in the subject line of the email. While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

We believe that equity and diversity are essential for the advancement of human knowledge and science.   We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

The GSC is part of BC Cancer Research Institute and the Provincial Health Services Authority (PHSA). Please note that as per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Research Associate–Bioinformatics

Job Reference No.; RA_R00006_Jones Lab_2021_09_28

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Research Associate to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. They will work with Project Leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within Dr. Steven Jones' lab at the GSC , you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. 

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties

  • Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data and set up collaborative working plans.
  • Develop and maintain bioinformatic pipelines for genome assembly and data analysis.
  • Produce written documentation of algorithms, validations, SOPs and other processes related to pipeline updates and procedures as required.
  • Present results of bioinformatics software testing internally and externally.
  • Perform literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
  • Perform other related duties as required.

Qualifications

  • Expertise in bioinformatics, emphasizing genome sequence analysis and gene annotation.
  • Knowledge and experience using scientific tools, technologies and online resources as pertaining to de novo genome assembly.
  • Fluency in multiple programming languages, including Python, Javascript and SQL.
  • Expertise developing and operating in a UNIX/Linus environment and writing shell scripts.
  • Experience developing custom scripts and pipelines using high performance computing and other available tools. Pipelines may include de novo assembly, annotation, database query, pan-genome construction and visualization tools, RNA-seq and phylogenetic tree reconstruction.
  • Previous API development projects using Open API or Rest API is a plus.
  • Excellent communication and organization skills, and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
  • Ability for critical thinking and independent learning.
  • Experience in a supervisory role is an asset.  

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_Jones Lab_2021_09_28 in the subject line of your email.

This position will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Postdoctoral Fellow–Bioinformatics

Job Reference No: PDF_01553_Jones Lab_2021_10_01

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Post-Doctoral Fellow to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. The successful incumbent will work with project leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within Dr. Steven Jones' lab at the GSC , you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. 

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties

  • Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data and set up collaborative working plans.
  • Develop and maintain bioinformatics pipelines for genome assembly and data analysis.
  • Produce written documentation of algorithms, validations, SOPs and other processes related to pipeline updates and procedures as required.
  • Present results of bioinformatics software testing internally and externally.
  • Perform literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
  • Perform other related duties as required.

Qualifications

  • Knowledge of genomics, genome assembly and genome analysis software.
  • Fluency in one or more programming languages, such as Python, Javascript and SQL.
  • Experience working in a UNIX/Linus environment and writing shell scripts.
  • Previous API development projects using Open API or Rest API is a plus.
  • Excellent communication and organization skills and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
  • Ability for critical thinking and independent learning.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using PDF_01553_Jones Lab_2021_10_01 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Business Analyst and Project Support

Job Reference No: RPC2_R00026_2021_07_06

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a Bachelor's degree in Health Information Science or Computer Science—along with experience in software/system project planning, analysis and implementation—this is your opportunity to join our team as a Business Analyst providing support for cutting-edge technology projects!

Reporting to the Head of Quality and Regulatory Affairs, the Business Analyst and Project Support (BA) leads the analysis and documentation of business requirements to support projects for designated programs and services. The successful candidate for this position will work in close collaboration with other stakeholders to develop business systems enhancements, business solutions, or business processes including GSC’s bioinformatics processes. The BA functions as a Subject Matter Expert to the project team through performing gap analysis of systems and business process mapping including the identification of linkages to other business systems.  

The BA position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now! 

Duties and Responsibilities

  • Provide key contributions to the development of solutions to ensure that business processes and/or project deliverables are consistent, accurate and timely.  
  • Participate in and contribute to strategic planning. 
  • Develop project plans for the design, development and implementation of new business processes; support the transition from current systems, practices and processes to an integrated system, common practices and standardized processes with current or improved functionality.  
  • Ensure key results are achieved in accordance with the project plan by analyzing current business systems and processes, generating ideas and formulating recommendations/options, and supporting members of the project in prioritizing tasks and reaching decisions that are within project scope and timelines. 
  • Implement or contribute to the implementation of effective processes to assess project risks, identify risk mitigation strategies and monitor risk throughout the project lifecycle. Support the Managers/Team Leads by providing regular updates on the progress as well as any areas of risk associated with the completion of the project both within the project scope and the timeline. Provide professional expertise to staff, departments, stakeholders, and guidance regarding standard process for project management.
  • Coordinate and participate in the analysis, acceptance criteria definition, development, testing, training, implementation and maintenance phases of assigned bioinformatics projects. Carry out post-implementation reviews of systems and make recommendations for improvements.
  • Utilize formal data gathering techniques and analysis tools such as flowcharts, diagrams, dashboards, roles and responsibility matrix (RACI) and work effort estimates. Provide details of estimated implementation costs including associated staffing requirements.
  • Review, analyze and define current/future state processes, determine user and/or department requirements and contribute to the development of specifications and testing for all identified development, system modifications and installations. Perform impact analyses. 
  • Provide user support, advice, guidance and orientation in situations that require interpretation and judgement. Develop content, as required, for training modules; deliver training and provide guidance to system users and department staff. Develop and maintain various business processes, policies and procedures, as well as reference documentation such as user instructions, manuals and reference materials.  
  • Provide support to colleagues and users during the development, maintenance and operation of various computer systems by performing duties such as troubleshooting system software problems and testing alternative solutions. 
  • Participate in the formal data collection and analysis to help identify system deficiencies and/or operational inefficiencies in order to report and develop new ways of improving business efficiencies including the data analysis related to business case developments, project proposals and other key strategic and transformative initiatives. 
  • Assemble, create and maintain information systems technical and operational documentation according to departmental standards.
  • Assist with preparation of Requests for Information/Proposal, development of evaluation processes and tools, and evaluation of vendor responses by serving on working groups, documenting detailed requirements and coordinating project team and vendor communications.

Qualifications

    • A level of education, training and experience equivalent to a Bachelor's degree in Health Information Science, Computer Science or a related discipline—OR relevant related experience that includes software/system project planning, analysis and implementation.  
    • Demonstrated ability to carry out business process mapping and fit gap analysis.  
    • Excellent interpersonal, oral and written communication skills with the ability manage multiple interactions with multiple groups while working on multiple issues at the same time.  
    • Superior analytical, problem-solving and system analysis skills.  
    • Proven ability to plan and execute projects with stringent timelines.  
    • Ability to work effectively as part of a team.  
    • Demonstrated ability to provide professional expertise to staff, departments and stakeholders, and guidance regarding standard processes for software/computer system related project management.  
    • Demonstrated ability to provide user support, advice and training, and other user liaison services.
    • Public Service and Health Sector experience and knowledge are an asset.  

    Apply

    Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Business Analyst and Project Support in the subject line of your email. 

    This posting will remain open until filled.

    Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

    As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

    We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. 

    We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

    All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

    About the GSC

    Canada’s Michael Smith Genome Sciences Centre (GSC)

    Today’s Research. Tomorrow’s Medicine.

    The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

    Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

    Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

    By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

    Process Development Coordinator–Clinical

    JOB ID: PCD_E00375_Clinical_2021_08_11

    Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you are a computational scientist with clinical laboratory experience, who has designed and performed computational experiments that generate clinically relevant results, who understands and can improve upon process development and programming workflows, and is motivated to contribute towards scientific endeavours with real benefits to improve the lives of cancer patients—then join us!

    As a Process Development Coordinator within the Clinical Bioinformatics Analysis team at the GSC, reporting to the Bioinformatics Group Leader, you will be responsible for leading the development, testing and validation of clinical bioinformatics processes. The PDC will develop new clinical procedures and bioinformatic workflows, monitor and review performance within the clinical production process, and where applicable, improve existing analyses; monitor results and compare them to best-practice standards; and always strives to streamline efficiency, maximize quality and balance cost. The PDC collaborates closely with key stakeholders for the clinical processes including the clinical director, bioinformatics groups and quality assurance group. You will need to be prepared to take initiative, to think critically and solve complex problems, to build and nurture collaborative relationships across departments, and to learn continuously.

    The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient, and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

    This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

    So, what are you waiting for? Apply now!

    Duties and Responsibilities

    Oversees the development and testing of clinical bioinformatics production processes by:

    • Designing and performing experiments pertaining to the generation of clinically relevant results.  This includes, but is not limited to, the development and testing of new analyses, protocol optimization, Quality Assurance and Quality Control, testing of prototypes and related activities. The PDC continually monitors performance of protocols within the production process and identifies areas for improvement. All activities will yield documented recommendations and implementation plans.
    • Troubleshooting existing clinical computational processes where necessary. Makes recommendations and adjustments and reports problems.
    • Training designated members of the clinical bioinformatics group in new or optimized analysis workflows. Writes or revises protocols accordingly.
    • Performing technical functions related to the Bioinformatics groups of the GSC.

    Qualifications

    • Graduation from a recognized Bachelor’s program in an appropriate discipline such as Computer Science, Bioinformatics, Genetics, Molecular Biology or Biochemistry—OR an acceptable equivalent combination of education, training and experience.
    • Proven expertise with Python and/or other similar high level languages.
    • Demonstrated ability in R or other similar statistical programming languages and in statistical analysis.
    • Functional knowledge of distributed version control systems, such as Git.
    • Demonstrated experience with next generation/ third generation sequencing technology with an in-depth understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
    • Excellent verbal and written communication skills.
    • Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
    • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
    • Experience liaising with multiple stakeholders to support consensus goals.
    • Demonstrated ability to efficiently organize work assignments and establish priorities to meet set milestones.
    • Demonstrated ability to write technical documents including validations and procedure manuals.
    • Excellent analytical skills.
    • Demonstrated ability to accept responsibility and work independently.
    • Experience with bioinformatic workflow managers, e.g., Nextflow, would be considered an asset.
    • Management experience is also an asset.

    Application

    Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using the Job Reference No. PCD_E00375_Clinical_2021_08_11 in the subject line of your email.

    This posting will remain online until filled.

    Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

    As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

    We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

    We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

    All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

    About the GSC

    Canada’s Michael Smith Genome Sciences Centre (GSC)

    Today’s Research. Tomorrow’s Medicine.

    The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

    Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

    Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

    By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values — science, timeliness, respect — to join us on our mission to use genome science for the betterment of health and society.

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