Exploring how patient-derived cancer models capture real tumour features
Researchers from the GSC’s Marra Lab found the genetics and cellular makeup of 3D model systems to be highly reflective of the brain tumours from which they were derived.
As researchers work towards establishing whole genome and transcriptome analysis into clinical practice for cancer care, scientists at the GSC continue developing innovative laboratory methods to improve efficiency and accuracy.
Cervical cancer disproportionately affects women in sub-Saharan Africa where it is the most common cancer-related mortality and has disease rates higher than any other region in the world (1). Yet studies of the disease have predominantly focused on non-African populations.
An international team of researchers, in work led by Canada’s Michael Smith Genome Sciences Centre (GSC) at BC Cancer, have now published an analysis of the genomic characteristics of cervical cancers in Ugandan women.