Sep 22, 2021

Tumor sequencing panel screens for both somatic and germline changes of clinical significance

The GSC has developed a next-generation sequencing test that can identify both acquired and inherited gene changes in tumor tissue. A paper published in the Journal of Molecular Diagnostics explains how this information can be used in the clinical management of patients with advanced cancers and their families.
Apr 09, 2020

Scientists reveal key insights into drug resistance in patients with del(5q) myelodysplastic syndrome

For myelodysplastic syndrome patients harbouring a particular genetic variant, lenalidomide is the drug of choice. But for about half of these patients, resistance will develop within two years, rendering the drug ineffective. By using DNA sequencing, scientists have now revealed key insights into drug resistance, uncovering a potential strategy for the early identification of patients who may not benefit from lenalidomide treatment.     
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