That’s the key idea put forth in preliminary research posted this month to bioRxiv, authored by GSC, UBC and BC Children's Hospital Research Institute scientists, that highlights the potential benefits of testing COVID-19 patients for genetic variants of ACE2—the protein identified as the point-of-entry for the SARS-COV-2 virus into human cells.
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New open-source interpretation and reporting platform for precision oncology
BC Cancer’s POG team has developed an open source platform for the interpretation and reporting of genomic data in precision oncology.
Sequencing the Spruce Weevil Genome
Why sequence a weevil? Understanding the insect’s genome could help control one of the most disruptive conifer pests in North America.
An alternative procedure for extracting nucleic acids for COVID-19 testing
Researchers in British Columbia have developed an optimized new protocol for extracting COVID-19 viral nucleic acids for PCR testing using generic reagents, including magnetic beads, on an open-deck liquid handling robot.
Giant’s Dot Lichen: from newly discovered species to complete genome sequence in one year
Two years ago, no one had ever heard of Bacidia gigatensis. Now, thanks to a team of researchers, science knows a lot about this lichen— including its genomic sequence.
A new method for analyzing silenced genes
Cancers are diseases of the genome. They can result from minor changes to single or a few base pairs, known as mutations, or from larger structural changes to the genome, including how it is packaged into chromosomes and manipulated by other molecules. Understanding how things have gone wrong in specific cancers can help scientists develop better prognostic tools and treatment strategies.
New study illustrates benefits of long-read sequencing technology for precision oncology
Whole genome sequencing has revolutionized cancer treatment planning, enabling the rapid detection of DNA mutations not routinely screened for in the clinic. Until recently, however, scientists were limited in their ability to detect large structural genetic variants using short-read sequencing technology. But with the recent release of long-read sequencing instruments, cancer researchers have been eager to see what such technology could mean for precision oncology.
B.C. scientists to begin genetic sequencing on Canadians with COVID-19
As part of a federal funding announcement earlier today, Canada’s Michael Smith Genome Sciences Centre (GSC) at BC Cancer will be one of four Canadian institutions on the forefront of using genome science to understand how different people respond to COVID-19 infection.
Scientists enhance important tool used to research the deadliest form of brain cancer
Genome and transcriptome profiling of human tumours grown in mice shows promise for a more accurate interpretation of research into Glioblastoma multiforme.