Looking at the genomic features of lung-recurrent, hormone-sensitive prostate cancer
The GSC’s Dr. Alexander Wyatt Lab assesses the genomic features of lung-recurrent, hormone-sensitive prostate cancer.
News
Genomic Analysis of Adrenocortical Cancer Identifies Treatment Targets
Results of whole-genome and transcriptome analysis identifies two genomic targets for potential treatment of adrenocortical cancer, a rare disease with limited therapeutic options.
Genome polishing: ntEdit+Sealer produces high quality long-read genome assemblies as a genome finishing protocol
The Birol Lab publishes ntEdit+Sealer, an alignment-free genome finishing protocol that corrects sequencing errors and fills gaps to produce highly accurate long-read genome assemblies.
Predicting Patient Response to Cancer Immunotherapy with Neoantigens
A study from the Karsan lab concludes that predicting patient response to immunotherapy is not improved using tumour neoantigen counts from noncoding DNA.
The importance in assessing genetic features of canine B-cell lymphomas
Dr. Ryan Morin’s laboratory publishes a recent study assessing the genomic features of canine B-cell lymphoma and highlights differences in human B-cell lymphoma.
The Canada BioGenome Project joins international quest to understand life on Earth
Part of a global effort to sequence, catalog, and characterize the genomes of life on Earth, the Canada BioGenome Project begins full scale sequencing.
Exploring how patient-derived cancer models capture real tumour features
Researchers from the GSC’s Marra Lab found the genetics and cellular makeup of 3D model systems to be highly reflective of the brain tumours from which they were derived.
Evaluating whole genome transcriptome analysis for cancer biomarker discovery and diagnosis
BC Cancer researchers assess whole genome transcriptome analysis for its ability to identify genomic biomarkers and predict the tumour site or tissue of origin for various cancers.
Autophagy machinery contributes to stress-induced secretion of proteins and extracellular vesicle populations
The Gorski Lab shows that chloroquine induces the secretion of autophagy-related proteins, some of which are partitioned and packaged into distinct small vesicle populations.