Journal
Bioinformatics, 2020
Authors
Sarah E I Perez, Aria S Hahn, Martin Krzywinski, Steven J Hallam

Motivation: Networks are used to relate topological structure to system dynamics and function, particularly in ecology and systems biology. Network analysis is often guided or complemented by data-driven visualization. Hive plots, one of many network visualizations, distinguish themselves as providing a general, consistent, and coherent rule-based representation to motivate hypothesis development and testing.

Results: Here, we present HyPE, Hive Panel Explorer, a software application that creates a panel of interactive hive plots. HyPE enables network exploration based on user-driven layout rules and parameter combinations for simultaneous rendering of multiple network views. We demonstrate HyPE's features by exploring a microbial co-occurrence network constructed from forest soil microbiomes.

Availability: HyPE is available under the GNU license: https://github.com/hallamlab/HivePanelExplorer. A wiki, including a tutorial, is available at https://github.com/hallamlab/HivePanelExplorer/wiki.

Supplementary information: Supplementary data are available at Bioinformatics online.

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