Alternative expression values of the type: KnownBoundary for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: KnownBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: KnownBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed KnownBoundary features

The following table provides a ranked list of alternatively expressed KnownBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 MICAL1 | E8_Da | (PostTx) | (PreTx)2.881.6412.08N/A83.37
2 AQP1 | E5_Dd | (PostTx) | (PreTx)-1.59-3.66-11.05N/A64.93
3 C17orf87 | E8_Da | (PostTx) | (PreTx)-1.44-3.75-10.21N/A63.72
4 C10orf54 | E2_Ab | (PostTx) | (PreTx)-2.38-1.95-10.19N/A77.64
5 C1S | E6_Ad | (PostTx) | (PreTx)-1.16-4.47-9.99N/A60.58
6 ANTXR1 | E23_Ab | (PostTx) | (PreTx)-1.27-4.03-9.72N/A62.01
7 VAMP1 | E4_Ab | (PostTx) | (PreTx)1.094.389.30N/A60.18
8 LAIR1 | E11_Db | (PostTx) | (PreTx)-1.67-2.44-7.76N/A69.71
9 MXRA7 | E5_Da | (PostTx) | (PreTx)-1.59-2.57-7.70N/A68.41
10 SLC12A8 | E14_Da | (PostTx) | (PreTx)-1.11-3.57-7.70N/A61.62
11 NCR3 | E1_Ab | (PostTx) | (PreTx)-1.66-2.39-7.55N/A69.92
12 EPHB1 | E11_Da | (PostTx) | (PreTx)1.093.477.39N/A61.64
13 DYNLT1 | E3_Da | (PostTx) | (PreTx)2.091.737.39N/A78.48
14 ZNF117 | E4_Db | (PostTx) | (PreTx)2.011.837.39N/A76.77
15 MBP | E15_Da | (PostTx) | (PreTx)2.721.117.33N/A94.85
16 AGXT2L2 | E5_Da | (PostTx) | (PreTx)1.841.946.96N/A74.47
17 NCDN | E1_Da | (PostTx) | (PreTx)2.391.306.81N/A88.11
18 NPHP3 | E45_Da | (PostTx) | (PreTx)1.392.606.81N/A66.75
19 ANKRD41 | E5_Da | (PostTx) | (PreTx)2.311.376.77N/A85.87
20 APLNR | E1_Ac | (PostTx) | (PreTx)-1.37-2.60-6.69N/A66.58
21 SH3PXD2A | E17_Da | (PostTx) | (PreTx)-1.12-3.07-6.66N/A62.84
22 PPM1A | E5_Db | (PostTx) | (PreTx)2.491.176.57N/A92.28
23 NDRG3 | E5_Da | (PostTx) | (PreTx)-2.06-1.57-6.54N/A80.69
24 CREBZF | E1_Ab | (PostTx) | (PreTx)1.482.346.52N/A68.79
25 MS4A1 | E2_Ab | (PostTx) | (PreTx)1.672.006.39N/A72.76
26 FOSL2 | E5_Da | (PostTx) | (PreTx)-1.13-2.92-6.38N/A63.36
27 WDR33 | E7_Ab | (PostTx) | (PreTx)2.591.046.23N/A98.13
28 OGFR | E2_Da | (PostTx) | (PreTx)2.69-1.046.23-1.0497.93
29 NPHP3 | E1_Ac | (PostTx) | (PreTx)1.252.606.19N/A65.63
30 RASSF4 | E3_Ab | (PostTx) | (PreTx)2.301.246.12N/A89.28
31 MICAL1 | E8_Ab | (PostTx) | (PreTx)1.891.646.11N/A78.45
32 NRIP1 | E4_Da | (PostTx) | (PreTx)-1.63-1.87-5.79N/A73.64
33 RASGRP2 | E4_Ae | (PostTx) | (PreTx)2.051.405.78N/A83.93
34 RAPH1 | E4_Da | (PostTx) | (PreTx)-1.04-2.82-5.78N/A62.89
35 BCL2L12 | E1_Ab | (PostTx) | (PreTx)-2.831.23-5.77-1.2789.39
36 CD40 | E4_Db | (PostTx) | (PreTx)1.212.465.68N/A65.84
37 POMT1 | E8_Da | (PostTx) | (PreTx)1.801.635.65N/A78.07
38 CCDC14 | E2_Ac | (PostTx) | (PreTx)1.172.515.65N/A65.26
39 QKI | E7_Ad | (PostTx) | (PreTx)-1.80-1.62-5.63N/A78.12
40 ZC3H12D | E8_Ab | (PostTx) | (PreTx)1.202.445.60N/A65.92
41 NCR3 | E2_Da | (PostTx) | (PreTx)-1.22-2.39-5.55N/A66.34
42 RAB24 | E4_Ab | (PostTx) | (PreTx)1.651.765.52N/A75.14
43 GLIPR2 | E8_Da | (PostTx) | (PreTx)-1.57-1.84-5.48N/A73.54
44 PH-4 | E6_Da | (PostTx) | (PreTx)1.292.215.41N/A68.00
45 ANKMY1 | E9_Da | (PostTx) | (PreTx)1.841.515.39N/A80.44
46 SPSB3 | E6_Ab | (PostTx) | (PreTx)1.581.785.32N/A74.40
47 SUPT7L | E2_Ab | (PostTx) | (PreTx)1.591.745.26N/A74.93
48 UBAP2 | E30_Dd | (PostTx) | (PreTx)2.071.255.25N/A88.01
49 GBA2 | E14_Ab | (PostTx) | (PreTx)1.791.525.25N/A79.76
50 SELPLG | E2_Db | (PostTx) | (PreTx)-1.10-2.44-5.25N/A65.02
51 DPY19L3 | E3_Ab | (PostTx) | (PreTx)2.071.245.21N/A88.38
52 CTLA4 | E4_Da | (PostTx) | (PreTx)1.102.415.18N/A65.14
53 PLEKHG2 | E20_Da | (PostTx) | (PreTx)1.461.865.12N/A72.41
54 C7orf27 | E5_Da | (PostTx) | (PreTx)2.081.205.06N/A89.82
55 FGFR1OP | E13_Da | (PostTx) | (PreTx)1.821.435.06N/A81.95
56 DYNLT1 | E3_Dc | (PostTx) | (PreTx)1.551.735.06N/A74.74
57 FANCL | E1_Ac | (PostTx) | (PreTx)1.541.745.06N/A74.45
58 INTS6 | E1_Da | (PostTx) | (PreTx)2.181.125.05N/A93.63
59 RPS27A | E6_Da | (PostTx) | (PreTx)1.012.475.00N/A63.99
60 TMEM102 | E1_Da | (PostTx) | (PreTx)-1.53-1.70-4.91N/A75.04
61 MPP1 | E3_Da | (PostTx) | (PreTx)-1.08-2.32-4.89N/A65.37
62 AC135457.2 | E1_Da | (PostTx) | (PreTx)1.931.224.66N/A88.38
63 ORMDL1 | E3_Ab | (PostTx) | (PreTx)1.461.694.66N/A74.59
64 BCL2L1 | E2_Ab | (PostTx) | (PreTx)2.26-1.044.57-1.0697.22
65 AC106788.3 | E6_Ab | (PostTx) | (PreTx)1.461.674.57N/A74.85
66 BTF3L4 | E6_Da | (PostTx) | (PreTx)-2.481.22-4.57-1.3088.36
67 TDRKH | E5_Da | (PostTx) | (PreTx)-2.06-1.09-4.57N/A94.49
68 CD9 | E2_Ab | (PostTx) | (PreTx)-1.03-2.23-4.55N/A65.42
69 IFRD1 | E2_Ab | (PostTx) | (PreTx)1.521.574.49N/A77.02
70 DAAM1 | E21_Ab | (PostTx) | (PreTx)1.531.544.46N/A77.46
71 KCNN4 | E1_Ab | (PostTx) | (PreTx)1.152.014.45N/A68.20
72 C22orf9 | E11_Da | (PostTx) | (PreTx)-1.05-2.15-4.45N/A66.11
73 SRRM2 | E16_Ab | (PostTx) | (PreTx)1.491.584.45N/A76.52
74 USP48 | E11_Da | (PostTx) | (PreTx)2.071.044.37N/A97.32
75 TIAL1 | E10_Da | (PostTx) | (PreTx)1.471.534.23N/A77.35
76 ITGA4 | E1_Ac | (PostTx) | (PreTx)-1.66-1.33-4.19N/A83.47
77 FLAD1 | E1_Da | (PostTx) | (PreTx)1.631.314.07N/A83.82
78 CAMSAP1 | E19_Da | (PostTx) | (PreTx)1.831.154.07N/A91.15
79 NNT | E23_Da | (PostTx) | (PreTx)2.15-1.094.07-1.1394.28
80 SLC2A11 | E5_Ab | (PostTx) | (PreTx)1.041.913.93N/A67.89
81 ODF2 | E7_Da | (PostTx) | (PreTx)1.691.213.89N/A87.76
82 RPL31 | E2_Dc | (PostTx) | (PreTx)1.321.523.82N/A76.07
83 PAQR3 | E8_Da | (PostTx) | (PreTx)-2.211.22-3.78-1.3586.94
84 UCRC | E2_Da | (PostTx) | (PreTx)1.251.593.77N/A74.12
85 C6orf61 | E12_Ab | (PostTx) | (PreTx)1.591.233.72N/A86.24
86 SEPT8 | E10_Ac | (PostTx) | (PreTx)-1.01-1.82-3.68N/A68.47
87 TRIM26 | E1_Ab | (PostTx) | (PreTx)-1.65-1.17-3.68N/A89.23
88 MRPL12 | E1_Ab | (PostTx) | (PreTx)1.761.083.66N/A94.24
89 MECP2 | E5_Da | (PostTx) | (PreTx)-1.35-1.44-3.65N/A78.13
90 NDEL1 | E1_Ab | (PostTx) | (PreTx)-1.41-1.36-3.61N/A80.64
91 ATP6V1C1 | E13_Da | (PostTx) | (PreTx)-1.25-1.50-3.56N/A75.86
92 RASGRP2 | E4_Ad | (PostTx) | (PreTx)1.341.403.55N/A79.03
93 ILI8BP | E2_Ae | (PostTx) | (PreTx)1.99-1.123.55-1.1991.85
94 SETDB2 | E7_Ab | (PostTx) | (PreTx)1.011.753.54N/A69.26
95 AP006216.9 | E20_Ab | (PostTx) | (PreTx)1.711.083.54N/A94.18
96 NCF4 | E8_Da | (PostTx) | (PreTx)1.601.153.49N/A89.69
97 C7orf43 | E13_Db | (PostTx) | (PreTx)1.031.703.47N/A70.15
98 CCDC86 | E1_Db | (PostTx) | (PreTx)-1.78-1.01-3.47N/A99.04
99 OAS1 | E6_Ab | (PostTx) | (PreTx)1.631.113.45N/A92.15
100 TBL1X | E20_Db | (PostTx) | (PreTx)-1.09-1.62-3.44N/A71.90
101 PRPF38B | E1_Ac | (PostTx) | (PreTx)1.181.513.43N/A74.90
102 TM9SF4 | E6_Ab | (PostTx) | (PreTx)-1.52-1.19-3.41N/A87.58
103 PLEKHA1 | E15_Db | (PostTx) | (PreTx)-1.03-1.63-3.34N/A71.05
104 BCAS3 | E16_Da | (PostTx) | (PreTx)-1.07-1.60-3.34N/A72.08
105 QKI | E7_Dc | (PostTx) | (PreTx)-1.04-1.62-3.34N/A71.34
106 ZNF419 | E10_Ad | (PostTx) | (PreTx)1.361.303.33N/A82.30
107 AFF2 | E24_Db | (PostTx) | (PreTx)1.491.183.30N/A87.94
108 LSR | E1_Da | (PostTx) | (PreTx)1.161.473.29N/A75.42
109 STARD3NL | E10_Da | (PostTx) | (PreTx)1.081.543.26N/A73.26
110 TNFRSF14 | E2_Ab | (PostTx) | (PreTx)1.111.513.26N/A74.25
111 RNF103 | E8_Da | (PostTx) | (PreTx)-1.29-1.32-3.23N/A80.70
112 TP53RK | E1_Ab | (PostTx) | (PreTx)1.88-1.143.22-1.2589.84
113 MAP3K2 | E17_Db | (PostTx) | (PreTx)-1.19-1.40-3.21N/A77.49
114 ZNF675 | E4_Db | (PostTx) | (PreTx)1.021.583.20N/A71.77
115 HRB | E15_Db | (PostTx) | (PreTx)-1.30-1.30-3.19N/A81.74
116 RAB2B | E4_Ab | (PostTx) | (PreTx)-1.921.19-3.18-1.3686.90
117 MAN1B1 | E13_Da | (PostTx) | (PreTx)-2.191.44-3.18-1.9276.05
118 CDCA4 | E2_Da | (PostTx) | (PreTx)1.231.333.11N/A79.96
119 KIAA1826 | E2_Ac | (PostTx) | (PreTx)1.591.033.11N/A97.09
120 CLIP1 | E11_Da | (PostTx) | (PreTx)-1.28-1.27-3.08N/A82.54
121 PRKCBP1 | E25_Db | (PostTx) | (PreTx)-1.54-1.05-3.06N/A95.66
122 RPL31 | E2_Da | (PostTx) | (PreTx)-2.211.52-3.04-2.2272.50
123 SHMT1 | E16_Da | (PostTx) | (PreTx)-1.33-1.20-3.03N/A85.74
124 GTPBP4 | E19_Ab | (PostTx) | (PreTx)-1.39-1.16-3.03N/A88.41
125 MRS2L | E11_Da | (PostTx) | (PreTx)1.011.472.97N/A73.82
126 DNAJC14 | E2_Da | (PostTx) | (PreTx)-1.30-1.21-2.97N/A85.22
127 ZMYM2 | E4_Ab | (PostTx) | (PreTx)1.331.182.96N/A86.98
128 LZIC | E9_Db | (PostTx) | (PreTx)-1.24-1.25-2.95N/A82.84
129 KLHL6 | E5_Dc | (PostTx) | (PreTx)1.011.472.95N/A73.72
130 MATR3 | E7_Ab | (PostTx) | (PreTx)-1.15-1.31-2.91N/A79.64
131 BCOR | E17_Da | (PostTx) | (PreTx)-1.45-1.06-2.89N/A95.17
132 FBRS | E7_Ab | (PostTx) | (PreTx)1.271.192.88N/A85.58
133 TLK1 | E24_Da | (PostTx) | (PreTx)-1.03-1.40-2.86N/A75.58
134 CRTC1 | E15_Ab | (PostTx) | (PreTx)1.281.182.86N/A86.65
135 PLEKHB2 | E1_Ab | (PostTx) | (PreTx)-1.02-1.41-2.85N/A75.34
136 ARPC5 | E1_Ac | (PostTx) | (PreTx)1.021.412.85N/A75.47
137 UNG | E2_Ab | (PostTx) | (PreTx)-1.24-1.20-2.84N/A85.00
138 VPRBP | E17_Ab | (PostTx) | (PreTx)-1.39-1.07-2.82N/A93.60
139 NIF3L1 | E8_Ab | (PostTx) | (PreTx)1.311.132.81N/A89.31
140 ANKRD11 | E10_Ac | (PostTx) | (PreTx)-1.03-1.36-2.78N/A76.86
141 RBM4 | E4_Da | (PostTx) | (PreTx)-1.40-1.04-2.74N/A96.15
142 AC093620.6 | E32_Da | (PostTx) | (PreTx)1.65-1.152.73-1.3287.79
143 TIMD4 | E10_Da | (PostTx) | (PreTx)1.08-5.75-2.71N/A36.31
144 KIAA0652 | E18_Da | (PostTx) | (PreTx)-1.08-1.28-2.71N/A80.07
145 SLC35B2 | E4_Ab | (PostTx) | (PreTx)1.401.032.70N/A97.33
146 PEX3 | E8_Da | (PostTx) | (PreTx)1.011.342.70N/A77.22
147 SPTY2D1 | E3_Da | (PostTx) | (PreTx)1.81-1.322.66-1.8077.80
148 NFYC | E4_Ab | (PostTx) | (PreTx)1.391.012.66N/A98.59
149 STX5 | E2_Ab | (PostTx) | (PreTx)-1.431.03-2.61-1.0796.82
150 RBMX2 | E1_Ab | (PostTx) | (PreTx)-1.02-1.28-2.61N/A79.27
151 PTRF | E1_Da | (PostTx) | (PreTx)1.02-5.21-2.57N/A36.36
152 TMSL3 | E1_Ab | (PostTx) | (PreTx)-1.941.50-2.56-2.5070.02
153 DYNC1I2 | E2_Ad | (PostTx) | (PreTx)-1.02-1.26-2.56N/A80.06
154 LYPLAL1 | E3_Ab | (PostTx) | (PreTx)-1.26-1.05-2.52N/A95.07
155 MAP3K7IP3 | E8_Ab | (PostTx) | (PreTx)1.48-1.112.51-1.2689.64
156 CLN5 | E4_Ab | (PostTx) | (PreTx)1.46-1.102.51-1.2390.61
157 HMGB1L15 | E1_Da | (PostTx) | (PreTx)-1.561.21-2.43-1.5582.26
158 SELM | E3_Ac | (PostTx) | (PreTx)-1.27-1.00-2.41N/A99.59
159 AC145132.2 | E6_Da | (PostTx) | (PreTx)1.251.012.40N/A99.17
160 SCAP | E12_Db | (PostTx) | (PreTx)1.31-1.062.34-1.1493.80
161 PNRC1 | E1_Da | (PostTx) | (PreTx)1.70-1.402.32-2.3571.26
162 PPM1B | E2_Da | (PostTx) | (PreTx)-1.01-1.14-2.30N/A86.42
163 KYNU | E18_Da | (PostTx) | (PreTx)1.36-1.112.30-1.3088.56
164 SEC16A | E19_Ab | (PostTx) | (PreTx)1.44-1.202.27-1.5682.00
165 SMARCC2 | E28_Da | (PostTx) | (PreTx)1.041.092.24N/A90.67
166 RBM12 | E2_Ab | (PostTx) | (PreTx)1.16-1.032.17-1.0796.77
167 HMGB1 | E8_Dd | (PostTx) | (PreTx)-1.09-1.02-2.16N/A97.83
168 HNRNPC | E3_Ab | (PostTx) | (PreTx)1.29-1.132.16-1.3886.17
169 BTN3A2 | E1_Ab | (PostTx) | (PreTx)-1.131.03-2.14-1.0796.67
170 NFX1 | E2_Ab | (PostTx) | (PreTx)1.21-1.092.13-1.2490.19
171 MFSD5 | E3_Ab | (PostTx) | (PreTx)1.19-1.112.06-1.3487.40
172 LY9 | E2_Ab | (PostTx) | (PreTx)-1.121.07-2.04-1.2091.73
173 HMGA1 | E1_Ab | (PostTx) | (PreTx)-1.321.24-2.00-1.9176.21