Alternative expression values of the type: KnownBoundary for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: KnownBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: KnownBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed KnownBoundary features

The following table provides a ranked list of alternatively expressed KnownBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 TMSL3 | E1_Ab | (PostTx) | (PreTx)-1.941.50-2.56-2.5070.02
2 PNRC1 | E1_Da | (PostTx) | (PreTx)1.70-1.402.32-2.3571.26
3 RPL31 | E2_Da | (PostTx) | (PreTx)-2.211.52-3.04-2.2272.50
4 MAN1B1 | E13_Da | (PostTx) | (PreTx)-2.191.44-3.18-1.9276.05
5 HMGA1 | E1_Ab | (PostTx) | (PreTx)-1.321.24-2.00-1.9176.21
6 SPTY2D1 | E3_Da | (PostTx) | (PreTx)1.81-1.322.66-1.8077.80
7 SEC16A | E19_Ab | (PostTx) | (PreTx)1.44-1.202.27-1.5682.00
8 HMGB1L15 | E1_Da | (PostTx) | (PreTx)-1.561.21-2.43-1.5582.26
9 HNRNPC | E3_Ab | (PostTx) | (PreTx)1.29-1.132.16-1.3886.17
10 RAB2B | E4_Ab | (PostTx) | (PreTx)-1.921.19-3.18-1.3686.90
11 PAQR3 | E8_Da | (PostTx) | (PreTx)-2.211.22-3.78-1.3586.94
12 MFSD5 | E3_Ab | (PostTx) | (PreTx)1.19-1.112.06-1.3487.40
13 AC093620.6 | E32_Da | (PostTx) | (PreTx)1.65-1.152.73-1.3287.79
14 BTF3L4 | E6_Da | (PostTx) | (PreTx)-2.481.22-4.57-1.3088.36
15 KYNU | E18_Da | (PostTx) | (PreTx)1.36-1.112.30-1.3088.56
16 BCL2L12 | E1_Ab | (PostTx) | (PreTx)-2.831.23-5.77-1.2789.39
17 MAP3K7IP3 | E8_Ab | (PostTx) | (PreTx)1.48-1.112.51-1.2689.64
18 TP53RK | E1_Ab | (PostTx) | (PreTx)1.88-1.143.22-1.2589.84
19 NFX1 | E2_Ab | (PostTx) | (PreTx)1.21-1.092.13-1.2490.19
20 CLN5 | E4_Ab | (PostTx) | (PreTx)1.46-1.102.51-1.2390.61
21 LY9 | E2_Ab | (PostTx) | (PreTx)-1.121.07-2.04-1.2091.73
22 ILI8BP | E2_Ae | (PostTx) | (PreTx)1.99-1.123.55-1.1991.85
23 SCAP | E12_Db | (PostTx) | (PreTx)1.31-1.062.34-1.1493.80
24 NNT | E23_Da | (PostTx) | (PreTx)2.15-1.094.07-1.1394.28
25 BTN3A2 | E1_Ab | (PostTx) | (PreTx)-1.131.03-2.14-1.0796.67
26 RBM12 | E2_Ab | (PostTx) | (PreTx)1.16-1.032.17-1.0796.77
27 STX5 | E2_Ab | (PostTx) | (PreTx)-1.431.03-2.61-1.0796.82
28 BCL2L1 | E2_Ab | (PostTx) | (PreTx)2.26-1.044.57-1.0697.22
29 OGFR | E2_Da | (PostTx) | (PreTx)2.69-1.046.23-1.0497.93
30 KIAA0652 | E18_Da | (PostTx) | (PreTx)-1.08-1.28-2.71N/A80.07
31 DYNC1I2 | E2_Ad | (PostTx) | (PreTx)-1.02-1.26-2.56N/A80.06
32 TBL1X | E20_Db | (PostTx) | (PreTx)-1.09-1.62-3.44N/A71.90
33 ANKMY1 | E9_Da | (PostTx) | (PreTx)1.841.515.39N/A80.44
34 OAS1 | E6_Ab | (PostTx) | (PreTx)1.631.113.45N/A92.15
35 UBAP2 | E30_Dd | (PostTx) | (PreTx)2.071.255.25N/A88.01
36 NCDN | E1_Da | (PostTx) | (PreTx)2.391.306.81N/A88.11
37 FLAD1 | E1_Da | (PostTx) | (PreTx)1.631.314.07N/A83.82
38 MS4A1 | E2_Ab | (PostTx) | (PreTx)1.672.006.39N/A72.76
39 POMT1 | E8_Da | (PostTx) | (PreTx)1.801.635.65N/A78.07
40 RASGRP2 | E4_Ae | (PostTx) | (PreTx)2.051.405.78N/A83.93
41 PRPF38B | E1_Ac | (PostTx) | (PreTx)1.181.513.43N/A74.90
42 CAMSAP1 | E19_Da | (PostTx) | (PreTx)1.831.154.07N/A91.15
43 TLK1 | E24_Da | (PostTx) | (PreTx)-1.03-1.40-2.86N/A75.58
44 SUPT7L | E2_Ab | (PostTx) | (PreTx)1.591.745.26N/A74.93
45 KCNN4 | E1_Ab | (PostTx) | (PreTx)1.152.014.45N/A68.20
46 CCDC14 | E2_Ac | (PostTx) | (PreTx)1.172.515.65N/A65.26
47 GTPBP4 | E19_Ab | (PostTx) | (PreTx)-1.39-1.16-3.03N/A88.41
48 QKI | E7_Dc | (PostTx) | (PreTx)-1.04-1.62-3.34N/A71.34
49 CCDC86 | E1_Db | (PostTx) | (PreTx)-1.78-1.01-3.47N/A99.04
50 PLEKHB2 | E1_Ab | (PostTx) | (PreTx)-1.02-1.41-2.85N/A75.34
51 C17orf87 | E8_Da | (PostTx) | (PreTx)-1.44-3.75-10.21N/A63.72
52 AGXT2L2 | E5_Da | (PostTx) | (PreTx)1.841.946.96N/A74.47
53 NDRG3 | E5_Da | (PostTx) | (PreTx)-2.06-1.57-6.54N/A80.69
54 MATR3 | E7_Ab | (PostTx) | (PreTx)-1.15-1.31-2.91N/A79.64
55 NPHP3 | E1_Ac | (PostTx) | (PreTx)1.252.606.19N/A65.63
56 RASSF4 | E3_Ab | (PostTx) | (PreTx)2.301.246.12N/A89.28
57 KLHL6 | E5_Dc | (PostTx) | (PreTx)1.011.472.95N/A73.72
58 CTLA4 | E4_Da | (PostTx) | (PreTx)1.102.415.18N/A65.14
59 SPSB3 | E6_Ab | (PostTx) | (PreTx)1.581.785.32N/A74.40
60 SELPLG | E2_Db | (PostTx) | (PreTx)-1.10-2.44-5.25N/A65.02
61 PH-4 | E6_Da | (PostTx) | (PreTx)1.292.215.41N/A68.00
62 SHMT1 | E16_Da | (PostTx) | (PreTx)-1.33-1.20-3.03N/A85.74
63 IFRD1 | E2_Ab | (PostTx) | (PreTx)1.521.574.49N/A77.02
64 CREBZF | E1_Ab | (PostTx) | (PreTx)1.482.346.52N/A68.79
65 SMARCC2 | E28_Da | (PostTx) | (PreTx)1.041.092.24N/A90.67
66 RAPH1 | E4_Da | (PostTx) | (PreTx)-1.04-2.82-5.78N/A62.89
67 CD40 | E4_Db | (PostTx) | (PreTx)1.212.465.68N/A65.84
68 TIMD4 | E10_Da | (PostTx) | (PreTx)1.08-5.75-2.71N/A36.31
69 UCRC | E2_Da | (PostTx) | (PreTx)1.251.593.77N/A74.12
70 AC145132.2 | E6_Da | (PostTx) | (PreTx)1.251.012.40N/A99.17
71 AC135457.2 | E1_Da | (PostTx) | (PreTx)1.931.224.66N/A88.38
72 SRRM2 | E16_Ab | (PostTx) | (PreTx)1.491.584.45N/A76.52
73 MRS2L | E11_Da | (PostTx) | (PreTx)1.011.472.97N/A73.82
74 CLIP1 | E11_Da | (PostTx) | (PreTx)-1.28-1.27-3.08N/A82.54
75 SLC35B2 | E4_Ab | (PostTx) | (PreTx)1.401.032.70N/A97.33
76 TM9SF4 | E6_Ab | (PostTx) | (PreTx)-1.52-1.19-3.41N/A87.58
77 DPY19L3 | E3_Ab | (PostTx) | (PreTx)2.071.245.21N/A88.38
78 PRKCBP1 | E25_Db | (PostTx) | (PreTx)-1.54-1.05-3.06N/A95.66
79 NRIP1 | E4_Da | (PostTx) | (PreTx)-1.63-1.87-5.79N/A73.64
80 FBRS | E7_Ab | (PostTx) | (PreTx)1.271.192.88N/A85.58
81 RBMX2 | E1_Ab | (PostTx) | (PreTx)-1.02-1.28-2.61N/A79.27
82 PPM1B | E2_Da | (PostTx) | (PreTx)-1.01-1.14-2.30N/A86.42
83 MBP | E15_Da | (PostTx) | (PreTx)2.721.117.33N/A94.85
84 RPL31 | E2_Dc | (PostTx) | (PreTx)1.321.523.82N/A76.07
85 VAMP1 | E4_Ab | (PostTx) | (PreTx)1.094.389.30N/A60.18
86 AQP1 | E5_Dd | (PostTx) | (PreTx)-1.59-3.66-11.05N/A64.93
87 MXRA7 | E5_Da | (PostTx) | (PreTx)-1.59-2.57-7.70N/A68.41
88 TNFRSF14 | E2_Ab | (PostTx) | (PreTx)1.111.513.26N/A74.25
89 APLNR | E1_Ac | (PostTx) | (PreTx)-1.37-2.60-6.69N/A66.58
90 ANKRD11 | E10_Ac | (PostTx) | (PreTx)-1.03-1.36-2.78N/A76.86
91 EPHB1 | E11_Da | (PostTx) | (PreTx)1.093.477.39N/A61.64
92 NDEL1 | E1_Ab | (PostTx) | (PreTx)-1.41-1.36-3.61N/A80.64
93 HMGB1 | E8_Dd | (PostTx) | (PreTx)-1.09-1.02-2.16N/A97.83
94 GBA2 | E14_Ab | (PostTx) | (PreTx)1.791.525.25N/A79.76
95 PLEKHA1 | E15_Db | (PostTx) | (PreTx)-1.03-1.63-3.34N/A71.05
96 INTS6 | E1_Da | (PostTx) | (PreTx)2.181.125.05N/A93.63
97 DNAJC14 | E2_Da | (PostTx) | (PreTx)-1.30-1.21-2.97N/A85.22
98 WDR33 | E7_Ab | (PostTx) | (PreTx)2.591.046.23N/A98.13
99 C7orf27 | E5_Da | (PostTx) | (PreTx)2.081.205.06N/A89.82
100 RNF103 | E8_Da | (PostTx) | (PreTx)-1.29-1.32-3.23N/A80.70
101 ANKRD41 | E5_Da | (PostTx) | (PreTx)2.311.376.77N/A85.87
102 GLIPR2 | E8_Da | (PostTx) | (PreTx)-1.57-1.84-5.48N/A73.54
103 RASGRP2 | E4_Ad | (PostTx) | (PreTx)1.341.403.55N/A79.03
104 ZNF419 | E10_Ad | (PostTx) | (PreTx)1.361.303.33N/A82.30
105 ORMDL1 | E3_Ab | (PostTx) | (PreTx)1.461.694.66N/A74.59
106 NCR3 | E2_Da | (PostTx) | (PreTx)-1.22-2.39-5.55N/A66.34
107 USP48 | E11_Da | (PostTx) | (PreTx)2.071.044.37N/A97.32
108 LZIC | E9_Db | (PostTx) | (PreTx)-1.24-1.25-2.95N/A82.84
109 ARPC5 | E1_Ac | (PostTx) | (PreTx)1.021.412.85N/A75.47
110 DAAM1 | E21_Ab | (PostTx) | (PreTx)1.531.544.46N/A77.46
111 STARD3NL | E10_Da | (PostTx) | (PreTx)1.081.543.26N/A73.26
112 MAP3K2 | E17_Db | (PostTx) | (PreTx)-1.19-1.40-3.21N/A77.49
113 FOSL2 | E5_Da | (PostTx) | (PreTx)-1.13-2.92-6.38N/A63.36
114 PLEKHG2 | E20_Da | (PostTx) | (PreTx)1.461.865.12N/A72.41
115 NFYC | E4_Ab | (PostTx) | (PreTx)1.391.012.66N/A98.59
116 CDCA4 | E2_Da | (PostTx) | (PreTx)1.231.333.11N/A79.96
117 SETDB2 | E7_Ab | (PostTx) | (PreTx)1.011.753.54N/A69.26
118 ITGA4 | E1_Ac | (PostTx) | (PreTx)-1.66-1.33-4.19N/A83.47
119 VPRBP | E17_Ab | (PostTx) | (PreTx)-1.39-1.07-2.82N/A93.60
120 ANTXR1 | E23_Ab | (PostTx) | (PreTx)-1.27-4.03-9.72N/A62.01
121 LYPLAL1 | E3_Ab | (PostTx) | (PreTx)-1.26-1.05-2.52N/A95.07
122 UNG | E2_Ab | (PostTx) | (PreTx)-1.24-1.20-2.84N/A85.00
123 MPP1 | E3_Da | (PostTx) | (PreTx)-1.08-2.32-4.89N/A65.37
124 ZNF675 | E4_Db | (PostTx) | (PreTx)1.021.583.20N/A71.77
125 ATP6V1C1 | E13_Da | (PostTx) | (PreTx)-1.25-1.50-3.56N/A75.86
126 CD9 | E2_Ab | (PostTx) | (PreTx)-1.03-2.23-4.55N/A65.42
127 LSR | E1_Da | (PostTx) | (PreTx)1.161.473.29N/A75.42
128 CRTC1 | E15_Ab | (PostTx) | (PreTx)1.281.182.86N/A86.65
129 ZMYM2 | E4_Ab | (PostTx) | (PreTx)1.331.182.96N/A86.98
130 NCF4 | E8_Da | (PostTx) | (PreTx)1.601.153.49N/A89.69
131 LAIR1 | E11_Db | (PostTx) | (PreTx)-1.67-2.44-7.76N/A69.71
132 C10orf54 | E2_Ab | (PostTx) | (PreTx)-2.38-1.95-10.19N/A77.64
133 QKI | E7_Ad | (PostTx) | (PreTx)-1.80-1.62-5.63N/A78.12
134 PTRF | E1_Da | (PostTx) | (PreTx)1.02-5.21-2.57N/A36.36
135 AP006216.9 | E20_Ab | (PostTx) | (PreTx)1.711.083.54N/A94.18
136 DYNLT1 | E3_Da | (PostTx) | (PreTx)2.091.737.39N/A78.48
137 C1S | E6_Ad | (PostTx) | (PreTx)-1.16-4.47-9.99N/A60.58
138 AC106788.3 | E6_Ab | (PostTx) | (PreTx)1.461.674.57N/A74.85
139 SELM | E3_Ac | (PostTx) | (PreTx)-1.27-1.00-2.41N/A99.59
140 BCOR | E17_Da | (PostTx) | (PreTx)-1.45-1.06-2.89N/A95.17
141 ODF2 | E7_Da | (PostTx) | (PreTx)1.691.213.89N/A87.76
142 FGFR1OP | E13_Da | (PostTx) | (PreTx)1.821.435.06N/A81.95
143 MICAL1 | E8_Ab | (PostTx) | (PreTx)1.891.646.11N/A78.45
144 DYNLT1 | E3_Dc | (PostTx) | (PreTx)1.551.735.06N/A74.74
145 SEPT8 | E10_Ac | (PostTx) | (PreTx)-1.01-1.82-3.68N/A68.47
146 TDRKH | E5_Da | (PostTx) | (PreTx)-2.06-1.09-4.57N/A94.49
147 TMEM102 | E1_Da | (PostTx) | (PreTx)-1.53-1.70-4.91N/A75.04
148 ZC3H12D | E8_Ab | (PostTx) | (PreTx)1.202.445.60N/A65.92
149 AFF2 | E24_Db | (PostTx) | (PreTx)1.491.183.30N/A87.94
150 FANCL | E1_Ac | (PostTx) | (PreTx)1.541.745.06N/A74.45
151 MRPL12 | E1_Ab | (PostTx) | (PreTx)1.761.083.66N/A94.24
152 MICAL1 | E8_Da | (PostTx) | (PreTx)2.881.6412.08N/A83.37
153 C22orf9 | E11_Da | (PostTx) | (PreTx)-1.05-2.15-4.45N/A66.11
154 ZNF117 | E4_Db | (PostTx) | (PreTx)2.011.837.39N/A76.77
155 RAB24 | E4_Ab | (PostTx) | (PreTx)1.651.765.52N/A75.14
156 HRB | E15_Db | (PostTx) | (PreTx)-1.30-1.30-3.19N/A81.74
157 SLC12A8 | E14_Da | (PostTx) | (PreTx)-1.11-3.57-7.70N/A61.62
158 NIF3L1 | E8_Ab | (PostTx) | (PreTx)1.311.132.81N/A89.31
159 PPM1A | E5_Db | (PostTx) | (PreTx)2.491.176.57N/A92.28
160 BCAS3 | E16_Da | (PostTx) | (PreTx)-1.07-1.60-3.34N/A72.08
161 TRIM26 | E1_Ab | (PostTx) | (PreTx)-1.65-1.17-3.68N/A89.23
162 RPS27A | E6_Da | (PostTx) | (PreTx)1.012.475.00N/A63.99
163 SH3PXD2A | E17_Da | (PostTx) | (PreTx)-1.12-3.07-6.66N/A62.84
164 C6orf61 | E12_Ab | (PostTx) | (PreTx)1.591.233.72N/A86.24
165 C7orf43 | E13_Db | (PostTx) | (PreTx)1.031.703.47N/A70.15
166 TIAL1 | E10_Da | (PostTx) | (PreTx)1.471.534.23N/A77.35
167 NCR3 | E1_Ab | (PostTx) | (PreTx)-1.66-2.39-7.55N/A69.92
168 PEX3 | E8_Da | (PostTx) | (PreTx)1.011.342.70N/A77.22
169 MECP2 | E5_Da | (PostTx) | (PreTx)-1.35-1.44-3.65N/A78.13
170 RBM4 | E4_Da | (PostTx) | (PreTx)-1.40-1.04-2.74N/A96.15
171 KIAA1826 | E2_Ac | (PostTx) | (PreTx)1.591.033.11N/A97.09
172 SLC2A11 | E5_Ab | (PostTx) | (PreTx)1.041.913.93N/A67.89
173 NPHP3 | E45_Da | (PostTx) | (PreTx)1.392.606.81N/A66.75