Alternative expression values of the type: NovelBoundary for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: NovelBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelBoundary features

The following table provides a ranked list of alternatively expressed NovelBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 EPHX1 | E9_Da | (PostTx) | (PreTx)4.09-3.614.72-10.5754.73
2 SYNE2 | E116_Aa | (PostTx) | (PreTx)3.54-1.965.93-2.2272.57
3 NPHP3 | E19_Aa | (PostTx) | (PreTx)-3.532.28-5.06-3.0666.34
4 CTNND1 | E22_Da | (PostTx) | (PreTx)3.44-1.825.97-2.0074.94
5 HECW2 | E28_Aa | (PostTx) | (PreTx)3.42-1.149.45-1.1294.61
6 CRELD2 | E10_Aa | (PostTx) | (PreTx)3.12-1.177.46-1.1792.81
7 PTOV1 | E10_Aa | (PostTx) | (PreTx)3.011.118.95N/A95.54
8 SYMPK | E2_Aa | (PostTx) | (PreTx)2.961.017.86N/A99.57
9 AC106782.5 | E13_Da | (PostTx) | (PreTx)-2.921.33-5.71-1.3986.06
10 ALKBH6 | E7_Aa | (PostTx) | (PreTx)2.901.6011.93N/A83.99
11 SFRS12 | E4_Da | (PostTx) | (PreTx)2.88-1.066.96-1.0697.06
12 RERE | E23_Aa | (PostTx) | (PreTx)2.851.188.48N/A92.93
13 ID2 | E3_Da | (PostTx) | (PreTx)2.75-1.195.66-1.2290.99
14 RNF166 | E2_Da | (PostTx) | (PreTx)2.72-1.105.97-1.1194.92
15 WBP1 | E2_Aa | (PostTx) | (PreTx)2.701.409.12N/A86.75
16 NPEPPS | E22_Aa | (PostTx) | (PreTx)2.70-1.155.66-1.1792.70
17 ZDHHC8 | E5_Aa | (PostTx) | (PreTx)2.691.237.96N/A90.86
18 FAM176B | E1_Da | (PostTx) | (PreTx)2.67-1.075.97-1.0896.40
19 DMAP1 | E6_Aa | (PostTx) | (PreTx)2.671.338.46N/A88.32
20 MMS19 | E8_Aa | (PostTx) | (PreTx)2.661.157.24N/A93.48
21 COG1 | E13_Da | (PostTx) | (PreTx)2.65-1.115.66-1.1294.47
22 USP34 | E80_Aa | (PostTx) | (PreTx)2.59-1.673.59-2.3571.26
23 GABPB1 | E1_Da | (PostTx) | (PreTx)2.55-1.165.09-1.1991.85
24 FAM38A | E37_Aa | (PostTx) | (PreTx)2.54-1.583.68-2.0874.04
25 CAMK1 | E10_Aa | (PostTx) | (PreTx)2.531.126.47N/A94.41
26 NARF | E12_Aa | (PostTx) | (PreTx)2.50-1.005.66-1.0099.87
27 FANCL | E13_Aa | (PostTx) | (PreTx)-2.481.53-3.64-1.9975.11
28 WDR39 | E6_Aa | (PostTx) | (PreTx)2.47-1.224.53-1.3188.31
29 TARBP1 | E24_Aa | (PostTx) | (PreTx)2.451.196.47N/A91.62
30 BTN3A3 | E4_Aa | (PostTx) | (PreTx)2.44-1.015.35-1.0199.33
31 NDUFB8 | E5_Aa | (PostTx) | (PreTx)2.431.176.29N/A92.29
32 ANKRD37 | E5_Aa | (PostTx) | (PreTx)-2.431.06-5.06-1.0896.51
33 DHRS4 | E1_Da | (PostTx) | (PreTx)-2.42-1.13-6.09N/A93.46
34 NME3 | E2_Da | (PostTx) | (PreTx)2.381.578.18N/A82.39
35 PAQR3 | E10_Da | (PostTx) | (PreTx)-2.381.08-4.83-1.1095.42
36 RP5-1077B9.4 | E6_Da | (PostTx) | (PreTx)2.351.236.29N/A89.82
37 PTCD3 | E19_Da | (PostTx) | (PreTx)2.321.306.47N/A87.71
38 PHKA2 | E29_Da | (PostTx) | (PreTx)2.271.456.96N/A84.03
39 ARSA | E2_Da | (PostTx) | (PreTx)2.251.537.24N/A82.41
40 STAT2 | E7_Aa | (PostTx) | (PreTx)2.241.155.44N/A92.45
41 CARKD | E10_Da | (PostTx) | (PreTx)2.241.376.47N/A85.51
42 CD47 | E7_Da | (PostTx) | (PreTx)2.23-1.014.64-1.0299.20
43 H3F3A | E5_Aa | (PostTx) | (PreTx)2.231.275.96N/A88.04
44 GUK1 | E8_Ab | (PostTx) | (PreTx)-2.211.22-3.77-1.3686.83
45 DGKD | E12_Da | (PostTx) | (PreTx)2.18-1.134.04-1.1992.18
46 CST3 | E2_Ac | (PostTx) | (PreTx)-2.18-6.76-30.68N/A64.18
47 KIAA0586 | E2_Aa | (PostTx) | (PreTx)-2.17-1.38-6.23N/A85.06
48 ZNF655 | E6_Aa | (PostTx) | (PreTx)2.151.135.03N/A92.89
49 DOM3Z | E2_Da | (PostTx) | (PreTx)2.151.576.96N/A81.06
50 USP21 | E11_Aa | (PostTx) | (PreTx)2.15-1.074.14-1.1095.58
51 DYNC1LI2 | E7_Da | (PostTx) | (PreTx)2.14-1.133.91-1.1991.97
52 WDR42A | E3_Aa | (PostTx) | (PreTx)2.111.185.06N/A90.95
53 MSTO1 | E7_Da | (PostTx) | (PreTx)2.101.516.47N/A81.85
54 WDR45 | E7_Dd | (PostTx) | (PreTx)2.091.265.35N/A88.06
55 AGXT2L2 | E11_Db | (PostTx) | (PreTx)-2.091.70-2.51-3.7463.39
56 POLM | E7_Da | (PostTx) | (PreTx)2.071.355.66N/A85.20
57 SPSB3 | E4_Aa | (PostTx) | (PreTx)2.041.566.43N/A80.75
58 SAP30BP | E10_Aa | (PostTx) | (PreTx)2.04-1.083.81-1.1294.50
59 FCHSD1 | E19_Aa | (PostTx) | (PreTx)2.011.857.46N/A76.53
60 CYTH1 | E14_Aa | (PostTx) | (PreTx)1.99-1.093.66-1.1493.93
61 DGKZ | E28_Da | (PostTx) | (PreTx)1.991.275.06N/A87.09
62 HLA-F | E3_Aa | (PostTx) | (PreTx)1.991.144.51N/A92.09
63 TMEM55B | E3_Aa | (PostTx) | (PreTx)1.951.365.25N/A84.41
64 SDR39U1 | E6_Da | (PostTx) | (PreTx)-1.951.38-2.79-1.9275.98
65 LIME1 | E3_Da | (PostTx) | (PreTx)-1.94-1.01-3.90N/A99.00
66 CEPT1 | E10_Aa | (PostTx) | (PreTx)-1.94-1.12-4.29N/A92.98
67 TIAL1 | E11_Aa | (PostTx) | (PreTx)1.941.335.10N/A85.04
68 FBRSL1 | E2_Aa | (PostTx) | (PreTx)1.931.575.98N/A79.96
69 DMAP1 | E5_Da | (PostTx) | (PreTx)1.921.335.03N/A85.13
70 YTHDC1 | E14_Aa | (PostTx) | (PreTx)1.90-1.402.66-2.0674.33
71 CAMK1 | E9_Da | (PostTx) | (PreTx)1.891.124.14N/A92.78
72 C21orf66 | E7_Da | (PostTx) | (PreTx)1.891.615.96N/A78.93
73 EXOSC8 | E5_Aa | (PostTx) | (PreTx)1.881.254.60N/A87.33
74 RELT | E8_Aa | (PostTx) | (PreTx)1.851.405.03N/A82.90
75 CCDC88A | E30_Aa | (PostTx) | (PreTx)1.841.324.71N/A84.91
76 FBXO9 | E10_Da | (PostTx) | (PreTx)1.841.505.35N/A80.62
77 NUP85 | E17_Da | (PostTx) | (PreTx)1.83-1.043.44-1.0697.19
78 HSH2D | E5_Aa | (PostTx) | (PreTx)1.822.027.13N/A73.64
79 NPAL2 | E10_Aa | (PostTx) | (PreTx)1.811.525.35N/A79.92
80 TAF11 | E4_Da | (PostTx) | (PreTx)1.811.806.29N/A75.86
81 CCDC49 | E5_Da | (PostTx) | (PreTx)1.801.123.91N/A92.27
82 TAZ | E6_Da | (PostTx) | (PreTx)1.801.535.35N/A79.66
83 C17orf65 | E3_Da | (PostTx) | (PreTx)1.801.264.37N/A86.58
84 FAM18A | E8_Aa | (PostTx) | (PreTx)-1.791.38-2.51-2.0874.07
85 ZNF207 | E2_Da | (PostTx) | (PreTx)-1.781.07-3.21-1.1294.78
86 HEXDC | E9_Da | (PostTx) | (PreTx)1.771.565.35N/A78.95
87 VMA21 | E3_Aa | (PostTx) | (PreTx)-1.77-1.32-4.49N/A84.49
88 FAM36A | E3_Aa | (PostTx) | (PreTx)1.76-1.073.18-1.1294.69
89 DEPDC5 | E38_Da | (PostTx) | (PreTx)1.761.023.45N/A98.73
90 KIAA0323 | E2_Da | (PostTx) | (PreTx)1.76-1.222.77-1.4983.47
91 TRAP1 | E17_Aa | (PostTx) | (PreTx)1.76-1.252.70-1.5981.41
92 C6orf192 | E9_Da | (PostTx) | (PreTx)-1.76-1.50-5.06N/A80.07
93 TBRG1 | E4_Aa | (PostTx) | (PreTx)1.721.274.17N/A85.76
94 CD40 | E4_Dc | (PostTx) | (PreTx)1.722.157.06N/A71.90
95 ZNF789 | E4_Da | (PostTx) | (PreTx)1.711.825.97N/A74.91
96 CDC42SE1 | E3_Da | (PostTx) | (PreTx)1.701.073.48N/A95.01
97 CAMK1 | E3_Aa | (PostTx) | (PreTx)1.701.123.63N/A92.09
98 HNRPDL | E7_Da | (PostTx) | (PreTx)1.701.133.67N/A91.31
99 PTOV1 | E9_Da | (PostTx) | (PreTx)1.691.113.57N/A92.56
100 FBXO44 | E6_Aa | (PostTx) | (PreTx)1.682.066.61N/A72.36
101 BRD9 | E4_Da | (PostTx) | (PreTx)-1.681.09-2.95-1.1692.97
102 AC145132.2 | E2_Aa | (PostTx) | (PreTx)-1.67-1.13-3.61N/A91.12
103 STK25 | E6_Aa | (PostTx) | (PreTx)1.661.233.89N/A86.85
104 CLK2 | E3_Da | (PostTx) | (PreTx)1.662.126.71N/A71.71
105 SFRS7 | E6_Aa | (PostTx) | (PreTx)1.661.344.24N/A83.10
106 METTL3 | E8_Da | (PostTx) | (PreTx)1.661.454.56N/A80.43
107 ZNF296 | E2_Da | (PostTx) | (PreTx)1.651.173.68N/A89.15
108 ANKZF1 | E9_Da | (PostTx) | (PreTx)1.651.835.75N/A74.29
109 C21orf66 | E8_Da | (PostTx) | (PreTx)1.641.615.03N/A77.24
110 NEIL1 | E5_Da | (PostTx) | (PreTx)1.643.5311.00N/A65.55
111 TOP3B | E19_Aa | (PostTx) | (PreTx)1.631.725.33N/A75.50
112 KCNMB3 | E2_Da | (PostTx) | (PreTx)-1.631.19-2.60-1.4484.66
113 RASGRP3 | E15_Da | (PostTx) | (PreTx)1.611.705.21N/A75.61
114 KLRK1 | E12_Aa | (PostTx) | (PreTx)1.601.975.98N/A72.46
115 SH3GLB2 | E8_Da | (PostTx) | (PreTx)1.581.745.22N/A74.82
116 RP11-345P4.4 | E7_Da | (PostTx) | (PreTx)1.581.073.18N/A94.71
117 WASH4P | E2_Aa | (PostTx) | (PreTx)1.572.627.81N/A68.08
118 DTNB | E15_Da | (PostTx) | (PreTx)1.571.133.35N/A90.81
119 OGT | E4_Da | (PostTx) | (PreTx)1.571.885.58N/A73.09
120 DDX54 | E18_Ab | (PostTx) | (PreTx)-1.56-1.24-3.65N/A85.87
121 TRA2A | E2_Aa | (PostTx) | (PreTx)1.551.273.73N/A84.53
122 ACADVL | E11_Aa | (PostTx) | (PreTx)1.541.002.92N/A99.86
123 MBD1 | E4_Da | (PostTx) | (PreTx)1.541.083.14N/A93.78
124 CDK5RAP3 | E6_Aa | (PostTx) | (PreTx)1.531.765.11N/A74.18
125 CCS | E4_Aa | (PostTx) | (PreTx)1.531.504.35N/A78.34
126 C3orf10 | E4_Aa | (PostTx) | (PreTx)-1.531.17-2.48-1.4085.59
127 EXOC7 | E6_Db | (PostTx) | (PreTx)1.52-1.132.54-1.3088.45
128 TAZ | E8_Aa | (PostTx) | (PreTx)1.511.534.37N/A77.50
129 OAT | E2_Ab | (PostTx) | (PreTx)-1.51-1.95-5.52N/A71.98
130 NIPBL | E46_Da | (PostTx) | (PreTx)-1.50-1.62-4.60N/A75.96
131 PAN2 | E23_Da | (PostTx) | (PreTx)1.501.865.26N/A72.81
132 NCR3 | E5_Da | (PostTx) | (PreTx)-1.50-2.71-7.65N/A67.12
133 DGKA | E12_Da | (PostTx) | (PreTx)1.491.042.93N/A96.53
134 SAT1 | E3_Aa | (PostTx) | (PreTx)1.49-1.022.77-1.0398.44
135 HECW2 | E29_Aa | (PostTx) | (PreTx)1.48-1.142.45-1.3387.51
136 SDR39U1 | E3_Aa | (PostTx) | (PreTx)1.461.383.81N/A80.49
137 HNRPDL | E8_Aa | (PostTx) | (PreTx)1.441.133.08N/A90.10
138 JAK3 | E13_Da | (PostTx) | (PreTx)1.44-1.002.71-1.0199.64
139 HNRNPH1 | E5_Aa | (PostTx) | (PreTx)1.441.163.16N/A88.42
140 DLG1 | E11_Db | (PostTx) | (PreTx)-1.44-1.17-3.16N/A88.22
141 SNAPC5 | E4_Aa | (PostTx) | (PreTx)-1.431.00-2.69-1.0199.69
142 ILF3 | E12_Aa | (PostTx) | (PreTx)1.421.233.31N/A85.09
143 TOP3B | E17_Da | (PostTx) | (PreTx)1.421.724.60N/A73.76
144 MSL3L1 | E9_Aa | (PostTx) | (PreTx)1.411.303.45N/A82.64
145 EIF4ENIF1 | E13_Db | (PostTx) | (PreTx)1.401.072.84N/A93.59
146 SNX22 | E2_Da | (PostTx) | (PreTx)1.402.275.98N/A68.62
147 QRICH1 | E8_Da | (PostTx) | (PreTx)1.401.032.72N/A97.21
148 ISGF3G | E18_Da | (PostTx) | (PreTx)1.401.193.14N/A86.62
149 SLC29A1 | E2_Ad | (PostTx) | (PreTx)-1.39-2.02-5.28N/A70.28
150 BTN2A2 | E1_Da | (PostTx) | (PreTx)-1.39-1.06-2.78N/A94.41
151 ZRANB3 | E25_Aa | (PostTx) | (PreTx)-1.38-1.03-2.68N/A97.22
152 PTOV1 | E9_Aa | (PostTx) | (PreTx)1.381.112.88N/A91.20
153 TSPAN14 | E14_Aa | (PostTx) | (PreTx)-1.38-1.97-5.11N/A70.63
154 PHF10 | E11_Da | (PostTx) | (PreTx)-1.371.15-2.25-1.4185.53
155 PRPF39 | E5_Aa | (PostTx) | (PreTx)1.371.834.71N/A72.00
156 N4BP2L2 | E5_Aa | (PostTx) | (PreTx)1.361.523.91N/A76.51
157 WDR6 | E3_Aa | (PostTx) | (PreTx)1.341.223.08N/A85.11
158 MICAL2 | E26_Db | (PostTx) | (PreTx)-1.34-2.23-5.65N/A68.30
159 AP1GBP1 | E1_Da | (PostTx) | (PreTx)-1.34-1.67-4.21N/A73.77
160 USP9X | E6_Ab | (PostTx) | (PreTx)-1.32-1.93-4.82N/A70.51
161 GGA2 | E4_Aa | (PostTx) | (PreTx)1.321.423.52N/A78.37
162 ASXL1 | E10_Aa | (PostTx) | (PreTx)1.311.223.01N/A84.94
163 TAP2 | E5_Da | (PostTx) | (PreTx)1.301.243.07N/A83.70
164 AC069281.6 | E4_Aa | (PostTx) | (PreTx)1.303.628.94N/A62.98
165 CFLAR | E7_Da | (PostTx) | (PreTx)1.30-1.112.23-1.2988.75
166 SEC14L1 | E1_Da | (PostTx) | (PreTx)-1.30-1.75-4.31N/A72.29
167 TRPT1 | E5_Da | (PostTx) | (PreTx)1.291.593.89N/A74.41
168 C9orf78 | E8_Ab | (PostTx) | (PreTx)-1.28-1.54-3.75N/A75.41
169 CRTC2 | E8_Aa | (PostTx) | (PreTx)1.281.112.70N/A90.28
170 NR2F2 | E2_Aa | (PostTx) | (PreTx)-1.27-3.05-7.39N/A64.18
171 SPSB3 | E5_Da | (PostTx) | (PreTx)1.241.563.68N/A74.61
172 ANO9 | E22_Aa | (PostTx) | (PreTx)1.241.543.63N/A75.03
173 ANKRD10 | E5_Da | (PostTx) | (PreTx)1.221.313.05N/A80.37
174 APBB3 | E2_Aa | (PostTx) | (PreTx)1.212.796.47N/A64.50
175 RHOT2 | E11_Aa | (PostTx) | (PreTx)1.211.834.21N/A70.48
176 NOP16 | E2_Da | (PostTx) | (PreTx)-1.201.03-2.25-1.0696.97
177 PRAMEL | E2_Da | (PostTx) | (PreTx)1.201.603.68N/A73.55
178 HNRNPH1 | E3_Da | (PostTx) | (PreTx)1.201.162.67N/A86.67
179 AC073264.5 | E1_Da | (PostTx) | (PreTx)-1.19-2.68-6.10N/A64.70
180 CALCOCO1 | E16_Aa | (PostTx) | (PreTx)1.171.212.72N/A84.24
181 PHLDB1 | E2_Ab | (PostTx) | (PreTx)-1.17-2.29-5.15N/A66.41
182 METT11D1 | E9_Da | (PostTx) | (PreTx)1.162.114.72N/A67.44
183 FADS3 | E2_Aa | (PostTx) | (PreTx)1.154.5710.13N/A60.38
184 PHF20 | E12_Da | (PostTx) | (PreTx)-1.14-1.77-3.90N/A70.52
185 AP000872.5 | E17_Da | (PostTx) | (PreTx)-1.14-2.55-5.63N/A64.84
186 COL6A3 | E2_Ab | (PostTx) | (PreTx)-1.14-8.52-18.76N/A57.78
187 IL2RA | E4_Da | (PostTx) | (PreTx)-1.13-1.38-3.01N/A77.45
188 SLC9A3R2 | E7_Aa | (PostTx) | (PreTx)-1.13-2.63-5.74N/A64.39
189 ZBTB48 | E5_Aa | (PostTx) | (PreTx)1.121.593.45N/A72.80
190 CHKB | E7_Aa | (PostTx) | (PreTx)1.122.284.94N/A65.96
191 SLC3A2 | E5_Aa | (PostTx) | (PreTx)-1.09-1.57-3.33N/A72.77
192 WDR81 | E4_Ab | (PostTx) | (PreTx)-1.08-1.49-3.17N/A74.18
193 CHKB | E2_Aa | (PostTx) | (PreTx)1.082.284.83N/A65.65
194 AC023024.6 | E6_Db | (PostTx) | (PreTx)-1.07-1.43-2.99N/A75.51
195 ANKZF1 | E10_Da | (PostTx) | (PreTx)1.051.833.80N/A68.81
196 HNRNPH1 | E2_Da | (PostTx) | (PreTx)1.051.162.40N/A85.32
197 TMEM140 | E2_Aa | (PostTx) | (PreTx)-1.04-2.01-4.12N/A66.98
198 GAK | E1_Da | (PostTx) | (PreTx)-1.03-1.23-2.53N/A81.48
199 SFRS5 | E5_Db | (PostTx) | (PreTx)1.031.553.18N/A72.36
200 CDK5RAP3 | E5_Da | (PostTx) | (PreTx)1.021.763.58N/A69.19
201 C3orf63 | E18_Aa | (PostTx) | (PreTx)-1.02-1.62-3.28N/A71.18
202 FOSB | E4_Aa | (PostTx) | (PreTx)-1.027.923.91N/A39.72
203 STUB1 | E6_Aa | (PostTx) | (PreTx)-1.02-1.18-2.40N/A83.76
204 TAF1C | E11_Da | (PostTx) | (PreTx)1.002.294.60N/A64.75