Alternative expression values of the type: NovelBoundary for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: NovelBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelBoundary features

The following table provides a ranked list of alternatively expressed NovelBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 NARF | E12_Aa | (PostTx) | (PreTx)2.50-1.005.66-1.0099.87
2 ACADVL | E11_Aa | (PostTx) | (PreTx)1.541.002.92N/A99.86
3 SNAPC5 | E4_Aa | (PostTx) | (PreTx)-1.431.00-2.69-1.0199.69
4 JAK3 | E13_Da | (PostTx) | (PreTx)1.44-1.002.71-1.0199.64
5 SYMPK | E2_Aa | (PostTx) | (PreTx)2.961.017.86N/A99.57
6 BTN3A3 | E4_Aa | (PostTx) | (PreTx)2.44-1.015.35-1.0199.33
7 CD47 | E7_Da | (PostTx) | (PreTx)2.23-1.014.64-1.0299.20
8 LIME1 | E3_Da | (PostTx) | (PreTx)-1.94-1.01-3.90N/A99.00
9 DEPDC5 | E38_Da | (PostTx) | (PreTx)1.761.023.45N/A98.73
10 SAT1 | E3_Aa | (PostTx) | (PreTx)1.49-1.022.77-1.0398.44
11 ZRANB3 | E25_Aa | (PostTx) | (PreTx)-1.38-1.03-2.68N/A97.22
12 QRICH1 | E8_Da | (PostTx) | (PreTx)1.401.032.72N/A97.21
13 NUP85 | E17_Da | (PostTx) | (PreTx)1.83-1.043.44-1.0697.19
14 SFRS12 | E4_Da | (PostTx) | (PreTx)2.88-1.066.96-1.0697.06
15 NOP16 | E2_Da | (PostTx) | (PreTx)-1.201.03-2.25-1.0696.97
16 DGKA | E12_Da | (PostTx) | (PreTx)1.491.042.93N/A96.53
17 ANKRD37 | E5_Aa | (PostTx) | (PreTx)-2.431.06-5.06-1.0896.51
18 FAM176B | E1_Da | (PostTx) | (PreTx)2.67-1.075.97-1.0896.40
19 USP21 | E11_Aa | (PostTx) | (PreTx)2.15-1.074.14-1.1095.58
20 PTOV1 | E10_Aa | (PostTx) | (PreTx)3.011.118.95N/A95.54
21 PAQR3 | E10_Da | (PostTx) | (PreTx)-2.381.08-4.83-1.1095.42
22 CDC42SE1 | E3_Da | (PostTx) | (PreTx)1.701.073.48N/A95.01
23 RNF166 | E2_Da | (PostTx) | (PreTx)2.72-1.105.97-1.1194.92
24 ZNF207 | E2_Da | (PostTx) | (PreTx)-1.781.07-3.21-1.1294.78
25 RP11-345P4.4 | E7_Da | (PostTx) | (PreTx)1.581.073.18N/A94.71
26 FAM36A | E3_Aa | (PostTx) | (PreTx)1.76-1.073.18-1.1294.69
27 HECW2 | E28_Aa | (PostTx) | (PreTx)3.42-1.149.45-1.1294.61
28 SAP30BP | E10_Aa | (PostTx) | (PreTx)2.04-1.083.81-1.1294.50
29 COG1 | E13_Da | (PostTx) | (PreTx)2.65-1.115.66-1.1294.47
30 BTN2A2 | E1_Da | (PostTx) | (PreTx)-1.39-1.06-2.78N/A94.41
31 CAMK1 | E10_Aa | (PostTx) | (PreTx)2.531.126.47N/A94.41
32 CYTH1 | E14_Aa | (PostTx) | (PreTx)1.99-1.093.66-1.1493.93
33 MBD1 | E4_Da | (PostTx) | (PreTx)1.541.083.14N/A93.78
34 EIF4ENIF1 | E13_Db | (PostTx) | (PreTx)1.401.072.84N/A93.59
35 MMS19 | E8_Aa | (PostTx) | (PreTx)2.661.157.24N/A93.48
36 DHRS4 | E1_Da | (PostTx) | (PreTx)-2.42-1.13-6.09N/A93.46
37 CEPT1 | E10_Aa | (PostTx) | (PreTx)-1.94-1.12-4.29N/A92.98
38 BRD9 | E4_Da | (PostTx) | (PreTx)-1.681.09-2.95-1.1692.97
39 RERE | E23_Aa | (PostTx) | (PreTx)2.851.188.48N/A92.93
40 ZNF655 | E6_Aa | (PostTx) | (PreTx)2.151.135.03N/A92.89
41 CRELD2 | E10_Aa | (PostTx) | (PreTx)3.12-1.177.46-1.1792.81
42 CAMK1 | E9_Da | (PostTx) | (PreTx)1.891.124.14N/A92.78
43 NPEPPS | E22_Aa | (PostTx) | (PreTx)2.70-1.155.66-1.1792.70
44 PTOV1 | E9_Da | (PostTx) | (PreTx)1.691.113.57N/A92.56
45 STAT2 | E7_Aa | (PostTx) | (PreTx)2.241.155.44N/A92.45
46 NDUFB8 | E5_Aa | (PostTx) | (PreTx)2.431.176.29N/A92.29
47 CCDC49 | E5_Da | (PostTx) | (PreTx)1.801.123.91N/A92.27
48 DGKD | E12_Da | (PostTx) | (PreTx)2.18-1.134.04-1.1992.18
49 CAMK1 | E3_Aa | (PostTx) | (PreTx)1.701.123.63N/A92.09
50 HLA-F | E3_Aa | (PostTx) | (PreTx)1.991.144.51N/A92.09
51 DYNC1LI2 | E7_Da | (PostTx) | (PreTx)2.14-1.133.91-1.1991.97
52 GABPB1 | E1_Da | (PostTx) | (PreTx)2.55-1.165.09-1.1991.85
53 TARBP1 | E24_Aa | (PostTx) | (PreTx)2.451.196.47N/A91.62
54 HNRPDL | E7_Da | (PostTx) | (PreTx)1.701.133.67N/A91.31
55 PTOV1 | E9_Aa | (PostTx) | (PreTx)1.381.112.88N/A91.20
56 AC145132.2 | E2_Aa | (PostTx) | (PreTx)-1.67-1.13-3.61N/A91.12
57 ID2 | E3_Da | (PostTx) | (PreTx)2.75-1.195.66-1.2290.99
58 WDR42A | E3_Aa | (PostTx) | (PreTx)2.111.185.06N/A90.95
59 ZDHHC8 | E5_Aa | (PostTx) | (PreTx)2.691.237.96N/A90.86
60 DTNB | E15_Da | (PostTx) | (PreTx)1.571.133.35N/A90.81
61 CRTC2 | E8_Aa | (PostTx) | (PreTx)1.281.112.70N/A90.28
62 HNRPDL | E8_Aa | (PostTx) | (PreTx)1.441.133.08N/A90.10
63 RP5-1077B9.4 | E6_Da | (PostTx) | (PreTx)2.351.236.29N/A89.82
64 ZNF296 | E2_Da | (PostTx) | (PreTx)1.651.173.68N/A89.15
65 CFLAR | E7_Da | (PostTx) | (PreTx)1.30-1.112.23-1.2988.75
66 EXOC7 | E6_Db | (PostTx) | (PreTx)1.52-1.132.54-1.3088.45
67 HNRNPH1 | E5_Aa | (PostTx) | (PreTx)1.441.163.16N/A88.42
68 DMAP1 | E6_Aa | (PostTx) | (PreTx)2.671.338.46N/A88.32
69 WDR39 | E6_Aa | (PostTx) | (PreTx)2.47-1.224.53-1.3188.31
70 DLG1 | E11_Db | (PostTx) | (PreTx)-1.44-1.17-3.16N/A88.22
71 WDR45 | E7_Dd | (PostTx) | (PreTx)2.091.265.35N/A88.06
72 H3F3A | E5_Aa | (PostTx) | (PreTx)2.231.275.96N/A88.04
73 PTCD3 | E19_Da | (PostTx) | (PreTx)2.321.306.47N/A87.71
74 HECW2 | E29_Aa | (PostTx) | (PreTx)1.48-1.142.45-1.3387.51
75 EXOSC8 | E5_Aa | (PostTx) | (PreTx)1.881.254.60N/A87.33
76 DGKZ | E28_Da | (PostTx) | (PreTx)1.991.275.06N/A87.09
77 STK25 | E6_Aa | (PostTx) | (PreTx)1.661.233.89N/A86.85
78 GUK1 | E8_Ab | (PostTx) | (PreTx)-2.211.22-3.77-1.3686.83
79 WBP1 | E2_Aa | (PostTx) | (PreTx)2.701.409.12N/A86.75
80 HNRNPH1 | E3_Da | (PostTx) | (PreTx)1.201.162.67N/A86.67
81 ISGF3G | E18_Da | (PostTx) | (PreTx)1.401.193.14N/A86.62
82 C17orf65 | E3_Da | (PostTx) | (PreTx)1.801.264.37N/A86.58
83 AC106782.5 | E13_Da | (PostTx) | (PreTx)-2.921.33-5.71-1.3986.06
84 DDX54 | E18_Ab | (PostTx) | (PreTx)-1.56-1.24-3.65N/A85.87
85 TBRG1 | E4_Aa | (PostTx) | (PreTx)1.721.274.17N/A85.76
86 C3orf10 | E4_Aa | (PostTx) | (PreTx)-1.531.17-2.48-1.4085.59
87 PHF10 | E11_Da | (PostTx) | (PreTx)-1.371.15-2.25-1.4185.53
88 CARKD | E10_Da | (PostTx) | (PreTx)2.241.376.47N/A85.51
89 HNRNPH1 | E2_Da | (PostTx) | (PreTx)1.051.162.40N/A85.32
90 POLM | E7_Da | (PostTx) | (PreTx)2.071.355.66N/A85.20
91 DMAP1 | E5_Da | (PostTx) | (PreTx)1.921.335.03N/A85.13
92 WDR6 | E3_Aa | (PostTx) | (PreTx)1.341.223.08N/A85.11
93 ILF3 | E12_Aa | (PostTx) | (PreTx)1.421.233.31N/A85.09
94 KIAA0586 | E2_Aa | (PostTx) | (PreTx)-2.17-1.38-6.23N/A85.06
95 TIAL1 | E11_Aa | (PostTx) | (PreTx)1.941.335.10N/A85.04
96 ASXL1 | E10_Aa | (PostTx) | (PreTx)1.311.223.01N/A84.94
97 CCDC88A | E30_Aa | (PostTx) | (PreTx)1.841.324.71N/A84.91
98 KCNMB3 | E2_Da | (PostTx) | (PreTx)-1.631.19-2.60-1.4484.66
99 TRA2A | E2_Aa | (PostTx) | (PreTx)1.551.273.73N/A84.53
100 VMA21 | E3_Aa | (PostTx) | (PreTx)-1.77-1.32-4.49N/A84.49
101 TMEM55B | E3_Aa | (PostTx) | (PreTx)1.951.365.25N/A84.41
102 CALCOCO1 | E16_Aa | (PostTx) | (PreTx)1.171.212.72N/A84.24
103 PHKA2 | E29_Da | (PostTx) | (PreTx)2.271.456.96N/A84.03
104 ALKBH6 | E7_Aa | (PostTx) | (PreTx)2.901.6011.93N/A83.99
105 STUB1 | E6_Aa | (PostTx) | (PreTx)-1.02-1.18-2.40N/A83.76
106 TAP2 | E5_Da | (PostTx) | (PreTx)1.301.243.07N/A83.70
107 KIAA0323 | E2_Da | (PostTx) | (PreTx)1.76-1.222.77-1.4983.47
108 SFRS7 | E6_Aa | (PostTx) | (PreTx)1.661.344.24N/A83.10
109 RELT | E8_Aa | (PostTx) | (PreTx)1.851.405.03N/A82.90
110 MSL3L1 | E9_Aa | (PostTx) | (PreTx)1.411.303.45N/A82.64
111 ARSA | E2_Da | (PostTx) | (PreTx)2.251.537.24N/A82.41
112 NME3 | E2_Da | (PostTx) | (PreTx)2.381.578.18N/A82.39
113 MSTO1 | E7_Da | (PostTx) | (PreTx)2.101.516.47N/A81.85
114 GAK | E1_Da | (PostTx) | (PreTx)-1.03-1.23-2.53N/A81.48
115 TRAP1 | E17_Aa | (PostTx) | (PreTx)1.76-1.252.70-1.5981.41
116 DOM3Z | E2_Da | (PostTx) | (PreTx)2.151.576.96N/A81.06
117 SPSB3 | E4_Aa | (PostTx) | (PreTx)2.041.566.43N/A80.75
118 FBXO9 | E10_Da | (PostTx) | (PreTx)1.841.505.35N/A80.62
119 SDR39U1 | E3_Aa | (PostTx) | (PreTx)1.461.383.81N/A80.49
120 METTL3 | E8_Da | (PostTx) | (PreTx)1.661.454.56N/A80.43
121 ANKRD10 | E5_Da | (PostTx) | (PreTx)1.221.313.05N/A80.37
122 C6orf192 | E9_Da | (PostTx) | (PreTx)-1.76-1.50-5.06N/A80.07
123 FBRSL1 | E2_Aa | (PostTx) | (PreTx)1.931.575.98N/A79.96
124 NPAL2 | E10_Aa | (PostTx) | (PreTx)1.811.525.35N/A79.92
125 TAZ | E6_Da | (PostTx) | (PreTx)1.801.535.35N/A79.66
126 HEXDC | E9_Da | (PostTx) | (PreTx)1.771.565.35N/A78.95
127 C21orf66 | E7_Da | (PostTx) | (PreTx)1.891.615.96N/A78.93
128 GGA2 | E4_Aa | (PostTx) | (PreTx)1.321.423.52N/A78.37
129 CCS | E4_Aa | (PostTx) | (PreTx)1.531.504.35N/A78.34
130 TAZ | E8_Aa | (PostTx) | (PreTx)1.511.534.37N/A77.50
131 IL2RA | E4_Da | (PostTx) | (PreTx)-1.13-1.38-3.01N/A77.45
132 C21orf66 | E8_Da | (PostTx) | (PreTx)1.641.615.03N/A77.24
133 FCHSD1 | E19_Aa | (PostTx) | (PreTx)2.011.857.46N/A76.53
134 N4BP2L2 | E5_Aa | (PostTx) | (PreTx)1.361.523.91N/A76.51
135 SDR39U1 | E6_Da | (PostTx) | (PreTx)-1.951.38-2.79-1.9275.98
136 NIPBL | E46_Da | (PostTx) | (PreTx)-1.50-1.62-4.60N/A75.96
137 TAF11 | E4_Da | (PostTx) | (PreTx)1.811.806.29N/A75.86
138 RASGRP3 | E15_Da | (PostTx) | (PreTx)1.611.705.21N/A75.61
139 AC023024.6 | E6_Db | (PostTx) | (PreTx)-1.07-1.43-2.99N/A75.51
140 TOP3B | E19_Aa | (PostTx) | (PreTx)1.631.725.33N/A75.50
141 C9orf78 | E8_Ab | (PostTx) | (PreTx)-1.28-1.54-3.75N/A75.41
142 FANCL | E13_Aa | (PostTx) | (PreTx)-2.481.53-3.64-1.9975.11
143 ANO9 | E22_Aa | (PostTx) | (PreTx)1.241.543.63N/A75.03
144 CTNND1 | E22_Da | (PostTx) | (PreTx)3.44-1.825.97-2.0074.94
145 ZNF789 | E4_Da | (PostTx) | (PreTx)1.711.825.97N/A74.91
146 SH3GLB2 | E8_Da | (PostTx) | (PreTx)1.581.745.22N/A74.82
147 SPSB3 | E5_Da | (PostTx) | (PreTx)1.241.563.68N/A74.61
148 TRPT1 | E5_Da | (PostTx) | (PreTx)1.291.593.89N/A74.41
149 YTHDC1 | E14_Aa | (PostTx) | (PreTx)1.90-1.402.66-2.0674.33
150 ANKZF1 | E9_Da | (PostTx) | (PreTx)1.651.835.75N/A74.29
151 CDK5RAP3 | E6_Aa | (PostTx) | (PreTx)1.531.765.11N/A74.18
152 WDR81 | E4_Ab | (PostTx) | (PreTx)-1.08-1.49-3.17N/A74.18
153 FAM18A | E8_Aa | (PostTx) | (PreTx)-1.791.38-2.51-2.0874.07
154 FAM38A | E37_Aa | (PostTx) | (PreTx)2.54-1.583.68-2.0874.04
155 AP1GBP1 | E1_Da | (PostTx) | (PreTx)-1.34-1.67-4.21N/A73.77
156 TOP3B | E17_Da | (PostTx) | (PreTx)1.421.724.60N/A73.76
157 HSH2D | E5_Aa | (PostTx) | (PreTx)1.822.027.13N/A73.64
158 PRAMEL | E2_Da | (PostTx) | (PreTx)1.201.603.68N/A73.55
159 OGT | E4_Da | (PostTx) | (PreTx)1.571.885.58N/A73.09
160 PAN2 | E23_Da | (PostTx) | (PreTx)1.501.865.26N/A72.81
161 ZBTB48 | E5_Aa | (PostTx) | (PreTx)1.121.593.45N/A72.80
162 SLC3A2 | E5_Aa | (PostTx) | (PreTx)-1.09-1.57-3.33N/A72.77
163 SYNE2 | E116_Aa | (PostTx) | (PreTx)3.54-1.965.93-2.2272.57
164 KLRK1 | E12_Aa | (PostTx) | (PreTx)1.601.975.98N/A72.46
165 FBXO44 | E6_Aa | (PostTx) | (PreTx)1.682.066.61N/A72.36
166 SFRS5 | E5_Db | (PostTx) | (PreTx)1.031.553.18N/A72.36
167 SEC14L1 | E1_Da | (PostTx) | (PreTx)-1.30-1.75-4.31N/A72.29
168 PRPF39 | E5_Aa | (PostTx) | (PreTx)1.371.834.71N/A72.00
169 OAT | E2_Ab | (PostTx) | (PreTx)-1.51-1.95-5.52N/A71.98
170 CD40 | E4_Dc | (PostTx) | (PreTx)1.722.157.06N/A71.90
171 CLK2 | E3_Da | (PostTx) | (PreTx)1.662.126.71N/A71.71
172 USP34 | E80_Aa | (PostTx) | (PreTx)2.59-1.673.59-2.3571.26
173 C3orf63 | E18_Aa | (PostTx) | (PreTx)-1.02-1.62-3.28N/A71.18
174 TSPAN14 | E14_Aa | (PostTx) | (PreTx)-1.38-1.97-5.11N/A70.63
175 PHF20 | E12_Da | (PostTx) | (PreTx)-1.14-1.77-3.90N/A70.52
176 USP9X | E6_Ab | (PostTx) | (PreTx)-1.32-1.93-4.82N/A70.51
177 RHOT2 | E11_Aa | (PostTx) | (PreTx)1.211.834.21N/A70.48
178 SLC29A1 | E2_Ad | (PostTx) | (PreTx)-1.39-2.02-5.28N/A70.28
179 CDK5RAP3 | E5_Da | (PostTx) | (PreTx)1.021.763.58N/A69.19
180 ANKZF1 | E10_Da | (PostTx) | (PreTx)1.051.833.80N/A68.81
181 SNX22 | E2_Da | (PostTx) | (PreTx)1.402.275.98N/A68.62
182 MICAL2 | E26_Db | (PostTx) | (PreTx)-1.34-2.23-5.65N/A68.30
183 WASH4P | E2_Aa | (PostTx) | (PreTx)1.572.627.81N/A68.08
184 METT11D1 | E9_Da | (PostTx) | (PreTx)1.162.114.72N/A67.44
185 NCR3 | E5_Da | (PostTx) | (PreTx)-1.50-2.71-7.65N/A67.12
186 TMEM140 | E2_Aa | (PostTx) | (PreTx)-1.04-2.01-4.12N/A66.98
187 PHLDB1 | E2_Ab | (PostTx) | (PreTx)-1.17-2.29-5.15N/A66.41
188 NPHP3 | E19_Aa | (PostTx) | (PreTx)-3.532.28-5.06-3.0666.34
189 CHKB | E7_Aa | (PostTx) | (PreTx)1.122.284.94N/A65.96
190 CHKB | E2_Aa | (PostTx) | (PreTx)1.082.284.83N/A65.65
191 NEIL1 | E5_Da | (PostTx) | (PreTx)1.643.5311.00N/A65.55
192 AP000872.5 | E17_Da | (PostTx) | (PreTx)-1.14-2.55-5.63N/A64.84
193 TAF1C | E11_Da | (PostTx) | (PreTx)1.002.294.60N/A64.75
194 AC073264.5 | E1_Da | (PostTx) | (PreTx)-1.19-2.68-6.10N/A64.70
195 APBB3 | E2_Aa | (PostTx) | (PreTx)1.212.796.47N/A64.50
196 SLC9A3R2 | E7_Aa | (PostTx) | (PreTx)-1.13-2.63-5.74N/A64.39
197 CST3 | E2_Ac | (PostTx) | (PreTx)-2.18-6.76-30.68N/A64.18
198 NR2F2 | E2_Aa | (PostTx) | (PreTx)-1.27-3.05-7.39N/A64.18
199 AGXT2L2 | E11_Db | (PostTx) | (PreTx)-2.091.70-2.51-3.7463.39
200 AC069281.6 | E4_Aa | (PostTx) | (PreTx)1.303.628.94N/A62.98
201 FADS3 | E2_Aa | (PostTx) | (PreTx)1.154.5710.13N/A60.38
202 COL6A3 | E2_Ab | (PostTx) | (PreTx)-1.14-8.52-18.76N/A57.78
203 EPHX1 | E9_Da | (PostTx) | (PreTx)4.09-3.614.72-10.5754.73
204 FOSB | E4_Aa | (PostTx) | (PreTx)-1.027.923.91N/A39.72