Alternative expression values of the type: NovelBoundary for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: NovelBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelBoundary features

The following table provides a ranked list of alternatively expressed NovelBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 COL6A3 | E2_Ab | (PostTx) | (PreTx)-1.14-8.52-18.76N/A57.78
2 FOSB | E4_Aa | (PostTx) | (PreTx)-1.027.923.91N/A39.72
3 CST3 | E2_Ac | (PostTx) | (PreTx)-2.18-6.76-30.68N/A64.18
4 FADS3 | E2_Aa | (PostTx) | (PreTx)1.154.5710.13N/A60.38
5 AC069281.6 | E4_Aa | (PostTx) | (PreTx)1.303.628.94N/A62.98
6 EPHX1 | E9_Da | (PostTx) | (PreTx)4.09-3.614.72-10.5754.73
7 NEIL1 | E5_Da | (PostTx) | (PreTx)1.643.5311.00N/A65.55
8 NR2F2 | E2_Aa | (PostTx) | (PreTx)-1.27-3.05-7.39N/A64.18
9 APBB3 | E2_Aa | (PostTx) | (PreTx)1.212.796.47N/A64.50
10 NCR3 | E5_Da | (PostTx) | (PreTx)-1.50-2.71-7.65N/A67.12
11 AC073264.5 | E1_Da | (PostTx) | (PreTx)-1.19-2.68-6.10N/A64.70
12 SLC9A3R2 | E7_Aa | (PostTx) | (PreTx)-1.13-2.63-5.74N/A64.39
13 WASH4P | E2_Aa | (PostTx) | (PreTx)1.572.627.81N/A68.08
14 AP000872.5 | E17_Da | (PostTx) | (PreTx)-1.14-2.55-5.63N/A64.84
15 TAF1C | E11_Da | (PostTx) | (PreTx)1.002.294.60N/A64.75
16 PHLDB1 | E2_Ab | (PostTx) | (PreTx)-1.17-2.29-5.15N/A66.41
17 CHKB | E7_Aa | (PostTx) | (PreTx)1.122.284.94N/A65.96
18 CHKB | E2_Aa | (PostTx) | (PreTx)1.082.284.83N/A65.65
19 NPHP3 | E19_Aa | (PostTx) | (PreTx)-3.532.28-5.06-3.0666.34
20 SNX22 | E2_Da | (PostTx) | (PreTx)1.402.275.98N/A68.62
21 MICAL2 | E26_Db | (PostTx) | (PreTx)-1.34-2.23-5.65N/A68.30
22 CD40 | E4_Dc | (PostTx) | (PreTx)1.722.157.06N/A71.90
23 CLK2 | E3_Da | (PostTx) | (PreTx)1.662.126.71N/A71.71
24 METT11D1 | E9_Da | (PostTx) | (PreTx)1.162.114.72N/A67.44
25 FBXO44 | E6_Aa | (PostTx) | (PreTx)1.682.066.61N/A72.36
26 SLC29A1 | E2_Ad | (PostTx) | (PreTx)-1.39-2.02-5.28N/A70.28
27 HSH2D | E5_Aa | (PostTx) | (PreTx)1.822.027.13N/A73.64
28 TMEM140 | E2_Aa | (PostTx) | (PreTx)-1.04-2.01-4.12N/A66.98
29 KLRK1 | E12_Aa | (PostTx) | (PreTx)1.601.975.98N/A72.46
30 TSPAN14 | E14_Aa | (PostTx) | (PreTx)-1.38-1.97-5.11N/A70.63
31 SYNE2 | E116_Aa | (PostTx) | (PreTx)3.54-1.965.93-2.2272.57
32 OAT | E2_Ab | (PostTx) | (PreTx)-1.51-1.95-5.52N/A71.98
33 USP9X | E6_Ab | (PostTx) | (PreTx)-1.32-1.93-4.82N/A70.51
34 OGT | E4_Da | (PostTx) | (PreTx)1.571.885.58N/A73.09
35 PAN2 | E23_Da | (PostTx) | (PreTx)1.501.865.26N/A72.81
36 FCHSD1 | E19_Aa | (PostTx) | (PreTx)2.011.857.46N/A76.53
37 ANKZF1 | E9_Da | (PostTx) | (PreTx)1.651.835.75N/A74.29
38 ANKZF1 | E10_Da | (PostTx) | (PreTx)1.051.833.80N/A68.81
39 PRPF39 | E5_Aa | (PostTx) | (PreTx)1.371.834.71N/A72.00
40 RHOT2 | E11_Aa | (PostTx) | (PreTx)1.211.834.21N/A70.48
41 ZNF789 | E4_Da | (PostTx) | (PreTx)1.711.825.97N/A74.91
42 CTNND1 | E22_Da | (PostTx) | (PreTx)3.44-1.825.97-2.0074.94
43 TAF11 | E4_Da | (PostTx) | (PreTx)1.811.806.29N/A75.86
44 PHF20 | E12_Da | (PostTx) | (PreTx)-1.14-1.77-3.90N/A70.52
45 CDK5RAP3 | E5_Da | (PostTx) | (PreTx)1.021.763.58N/A69.19
46 CDK5RAP3 | E6_Aa | (PostTx) | (PreTx)1.531.765.11N/A74.18
47 SEC14L1 | E1_Da | (PostTx) | (PreTx)-1.30-1.75-4.31N/A72.29
48 SH3GLB2 | E8_Da | (PostTx) | (PreTx)1.581.745.22N/A74.82
49 TOP3B | E19_Aa | (PostTx) | (PreTx)1.631.725.33N/A75.50
50 TOP3B | E17_Da | (PostTx) | (PreTx)1.421.724.60N/A73.76
51 RASGRP3 | E15_Da | (PostTx) | (PreTx)1.611.705.21N/A75.61
52 AGXT2L2 | E11_Db | (PostTx) | (PreTx)-2.091.70-2.51-3.7463.39
53 USP34 | E80_Aa | (PostTx) | (PreTx)2.59-1.673.59-2.3571.26
54 AP1GBP1 | E1_Da | (PostTx) | (PreTx)-1.34-1.67-4.21N/A73.77
55 NIPBL | E46_Da | (PostTx) | (PreTx)-1.50-1.62-4.60N/A75.96
56 C3orf63 | E18_Aa | (PostTx) | (PreTx)-1.02-1.62-3.28N/A71.18
57 C21orf66 | E7_Da | (PostTx) | (PreTx)1.891.615.96N/A78.93
58 C21orf66 | E8_Da | (PostTx) | (PreTx)1.641.615.03N/A77.24
59 ALKBH6 | E7_Aa | (PostTx) | (PreTx)2.901.6011.93N/A83.99
60 PRAMEL | E2_Da | (PostTx) | (PreTx)1.201.603.68N/A73.55
61 TRPT1 | E5_Da | (PostTx) | (PreTx)1.291.593.89N/A74.41
62 ZBTB48 | E5_Aa | (PostTx) | (PreTx)1.121.593.45N/A72.80
63 FAM38A | E37_Aa | (PostTx) | (PreTx)2.54-1.583.68-2.0874.04
64 DOM3Z | E2_Da | (PostTx) | (PreTx)2.151.576.96N/A81.06
65 SLC3A2 | E5_Aa | (PostTx) | (PreTx)-1.09-1.57-3.33N/A72.77
66 NME3 | E2_Da | (PostTx) | (PreTx)2.381.578.18N/A82.39
67 FBRSL1 | E2_Aa | (PostTx) | (PreTx)1.931.575.98N/A79.96
68 HEXDC | E9_Da | (PostTx) | (PreTx)1.771.565.35N/A78.95
69 SPSB3 | E4_Aa | (PostTx) | (PreTx)2.041.566.43N/A80.75
70 SPSB3 | E5_Da | (PostTx) | (PreTx)1.241.563.68N/A74.61
71 SFRS5 | E5_Db | (PostTx) | (PreTx)1.031.553.18N/A72.36
72 C9orf78 | E8_Ab | (PostTx) | (PreTx)-1.28-1.54-3.75N/A75.41
73 ANO9 | E22_Aa | (PostTx) | (PreTx)1.241.543.63N/A75.03
74 TAZ | E8_Aa | (PostTx) | (PreTx)1.511.534.37N/A77.50
75 TAZ | E6_Da | (PostTx) | (PreTx)1.801.535.35N/A79.66
76 FANCL | E13_Aa | (PostTx) | (PreTx)-2.481.53-3.64-1.9975.11
77 ARSA | E2_Da | (PostTx) | (PreTx)2.251.537.24N/A82.41
78 NPAL2 | E10_Aa | (PostTx) | (PreTx)1.811.525.35N/A79.92
79 N4BP2L2 | E5_Aa | (PostTx) | (PreTx)1.361.523.91N/A76.51
80 MSTO1 | E7_Da | (PostTx) | (PreTx)2.101.516.47N/A81.85
81 CCS | E4_Aa | (PostTx) | (PreTx)1.531.504.35N/A78.34
82 C6orf192 | E9_Da | (PostTx) | (PreTx)-1.76-1.50-5.06N/A80.07
83 FBXO9 | E10_Da | (PostTx) | (PreTx)1.841.505.35N/A80.62
84 WDR81 | E4_Ab | (PostTx) | (PreTx)-1.08-1.49-3.17N/A74.18
85 METTL3 | E8_Da | (PostTx) | (PreTx)1.661.454.56N/A80.43
86 PHKA2 | E29_Da | (PostTx) | (PreTx)2.271.456.96N/A84.03
87 AC023024.6 | E6_Db | (PostTx) | (PreTx)-1.07-1.43-2.99N/A75.51
88 GGA2 | E4_Aa | (PostTx) | (PreTx)1.321.423.52N/A78.37
89 YTHDC1 | E14_Aa | (PostTx) | (PreTx)1.90-1.402.66-2.0674.33
90 WBP1 | E2_Aa | (PostTx) | (PreTx)2.701.409.12N/A86.75
91 RELT | E8_Aa | (PostTx) | (PreTx)1.851.405.03N/A82.90
92 SDR39U1 | E6_Da | (PostTx) | (PreTx)-1.951.38-2.79-1.9275.98
93 SDR39U1 | E3_Aa | (PostTx) | (PreTx)1.461.383.81N/A80.49
94 FAM18A | E8_Aa | (PostTx) | (PreTx)-1.791.38-2.51-2.0874.07
95 IL2RA | E4_Da | (PostTx) | (PreTx)-1.13-1.38-3.01N/A77.45
96 KIAA0586 | E2_Aa | (PostTx) | (PreTx)-2.17-1.38-6.23N/A85.06
97 CARKD | E10_Da | (PostTx) | (PreTx)2.241.376.47N/A85.51
98 TMEM55B | E3_Aa | (PostTx) | (PreTx)1.951.365.25N/A84.41
99 POLM | E7_Da | (PostTx) | (PreTx)2.071.355.66N/A85.20
100 SFRS7 | E6_Aa | (PostTx) | (PreTx)1.661.344.24N/A83.10
101 TIAL1 | E11_Aa | (PostTx) | (PreTx)1.941.335.10N/A85.04
102 DMAP1 | E5_Da | (PostTx) | (PreTx)1.921.335.03N/A85.13
103 DMAP1 | E6_Aa | (PostTx) | (PreTx)2.671.338.46N/A88.32
104 AC106782.5 | E13_Da | (PostTx) | (PreTx)-2.921.33-5.71-1.3986.06
105 VMA21 | E3_Aa | (PostTx) | (PreTx)-1.77-1.32-4.49N/A84.49
106 CCDC88A | E30_Aa | (PostTx) | (PreTx)1.841.324.71N/A84.91
107 ANKRD10 | E5_Da | (PostTx) | (PreTx)1.221.313.05N/A80.37
108 PTCD3 | E19_Da | (PostTx) | (PreTx)2.321.306.47N/A87.71
109 MSL3L1 | E9_Aa | (PostTx) | (PreTx)1.411.303.45N/A82.64
110 H3F3A | E5_Aa | (PostTx) | (PreTx)2.231.275.96N/A88.04
111 TRA2A | E2_Aa | (PostTx) | (PreTx)1.551.273.73N/A84.53
112 DGKZ | E28_Da | (PostTx) | (PreTx)1.991.275.06N/A87.09
113 TBRG1 | E4_Aa | (PostTx) | (PreTx)1.721.274.17N/A85.76
114 C17orf65 | E3_Da | (PostTx) | (PreTx)1.801.264.37N/A86.58
115 WDR45 | E7_Dd | (PostTx) | (PreTx)2.091.265.35N/A88.06
116 TRAP1 | E17_Aa | (PostTx) | (PreTx)1.76-1.252.70-1.5981.41
117 EXOSC8 | E5_Aa | (PostTx) | (PreTx)1.881.254.60N/A87.33
118 TAP2 | E5_Da | (PostTx) | (PreTx)1.301.243.07N/A83.70
119 DDX54 | E18_Ab | (PostTx) | (PreTx)-1.56-1.24-3.65N/A85.87
120 GAK | E1_Da | (PostTx) | (PreTx)-1.03-1.23-2.53N/A81.48
121 ILF3 | E12_Aa | (PostTx) | (PreTx)1.421.233.31N/A85.09
122 ZDHHC8 | E5_Aa | (PostTx) | (PreTx)2.691.237.96N/A90.86
123 RP5-1077B9.4 | E6_Da | (PostTx) | (PreTx)2.351.236.29N/A89.82
124 STK25 | E6_Aa | (PostTx) | (PreTx)1.661.233.89N/A86.85
125 KIAA0323 | E2_Da | (PostTx) | (PreTx)1.76-1.222.77-1.4983.47
126 GUK1 | E8_Ab | (PostTx) | (PreTx)-2.211.22-3.77-1.3686.83
127 WDR39 | E6_Aa | (PostTx) | (PreTx)2.47-1.224.53-1.3188.31
128 WDR6 | E3_Aa | (PostTx) | (PreTx)1.341.223.08N/A85.11
129 ASXL1 | E10_Aa | (PostTx) | (PreTx)1.311.223.01N/A84.94
130 CALCOCO1 | E16_Aa | (PostTx) | (PreTx)1.171.212.72N/A84.24
131 ISGF3G | E18_Da | (PostTx) | (PreTx)1.401.193.14N/A86.62
132 KCNMB3 | E2_Da | (PostTx) | (PreTx)-1.631.19-2.60-1.4484.66
133 ID2 | E3_Da | (PostTx) | (PreTx)2.75-1.195.66-1.2290.99
134 TARBP1 | E24_Aa | (PostTx) | (PreTx)2.451.196.47N/A91.62
135 STUB1 | E6_Aa | (PostTx) | (PreTx)-1.02-1.18-2.40N/A83.76
136 RERE | E23_Aa | (PostTx) | (PreTx)2.851.188.48N/A92.93
137 WDR42A | E3_Aa | (PostTx) | (PreTx)2.111.185.06N/A90.95
138 ZNF296 | E2_Da | (PostTx) | (PreTx)1.651.173.68N/A89.15
139 CRELD2 | E10_Aa | (PostTx) | (PreTx)3.12-1.177.46-1.1792.81
140 DLG1 | E11_Db | (PostTx) | (PreTx)-1.44-1.17-3.16N/A88.22
141 NDUFB8 | E5_Aa | (PostTx) | (PreTx)2.431.176.29N/A92.29
142 C3orf10 | E4_Aa | (PostTx) | (PreTx)-1.531.17-2.48-1.4085.59
143 HNRNPH1 | E5_Aa | (PostTx) | (PreTx)1.441.163.16N/A88.42
144 HNRNPH1 | E2_Da | (PostTx) | (PreTx)1.051.162.40N/A85.32
145 HNRNPH1 | E3_Da | (PostTx) | (PreTx)1.201.162.67N/A86.67
146 GABPB1 | E1_Da | (PostTx) | (PreTx)2.55-1.165.09-1.1991.85
147 STAT2 | E7_Aa | (PostTx) | (PreTx)2.241.155.44N/A92.45
148 MMS19 | E8_Aa | (PostTx) | (PreTx)2.661.157.24N/A93.48
149 PHF10 | E11_Da | (PostTx) | (PreTx)-1.371.15-2.25-1.4185.53
150 NPEPPS | E22_Aa | (PostTx) | (PreTx)2.70-1.155.66-1.1792.70
151 HLA-F | E3_Aa | (PostTx) | (PreTx)1.991.144.51N/A92.09
152 HECW2 | E29_Aa | (PostTx) | (PreTx)1.48-1.142.45-1.3387.51
153 HECW2 | E28_Aa | (PostTx) | (PreTx)3.42-1.149.45-1.1294.61
154 DHRS4 | E1_Da | (PostTx) | (PreTx)-2.42-1.13-6.09N/A93.46
155 AC145132.2 | E2_Aa | (PostTx) | (PreTx)-1.67-1.13-3.61N/A91.12
156 ZNF655 | E6_Aa | (PostTx) | (PreTx)2.151.135.03N/A92.89
157 HNRPDL | E7_Da | (PostTx) | (PreTx)1.701.133.67N/A91.31
158 HNRPDL | E8_Aa | (PostTx) | (PreTx)1.441.133.08N/A90.10
159 DTNB | E15_Da | (PostTx) | (PreTx)1.571.133.35N/A90.81
160 EXOC7 | E6_Db | (PostTx) | (PreTx)1.52-1.132.54-1.3088.45
161 DYNC1LI2 | E7_Da | (PostTx) | (PreTx)2.14-1.133.91-1.1991.97
162 DGKD | E12_Da | (PostTx) | (PreTx)2.18-1.134.04-1.1992.18
163 CCDC49 | E5_Da | (PostTx) | (PreTx)1.801.123.91N/A92.27
164 CAMK1 | E3_Aa | (PostTx) | (PreTx)1.701.123.63N/A92.09
165 CAMK1 | E9_Da | (PostTx) | (PreTx)1.891.124.14N/A92.78
166 CAMK1 | E10_Aa | (PostTx) | (PreTx)2.531.126.47N/A94.41
167 CEPT1 | E10_Aa | (PostTx) | (PreTx)-1.94-1.12-4.29N/A92.98
168 CRTC2 | E8_Aa | (PostTx) | (PreTx)1.281.112.70N/A90.28
169 PTOV1 | E9_Da | (PostTx) | (PreTx)1.691.113.57N/A92.56
170 PTOV1 | E9_Aa | (PostTx) | (PreTx)1.381.112.88N/A91.20
171 PTOV1 | E10_Aa | (PostTx) | (PreTx)3.011.118.95N/A95.54
172 COG1 | E13_Da | (PostTx) | (PreTx)2.65-1.115.66-1.1294.47
173 CFLAR | E7_Da | (PostTx) | (PreTx)1.30-1.112.23-1.2988.75
174 RNF166 | E2_Da | (PostTx) | (PreTx)2.72-1.105.97-1.1194.92
175 CYTH1 | E14_Aa | (PostTx) | (PreTx)1.99-1.093.66-1.1493.93
176 BRD9 | E4_Da | (PostTx) | (PreTx)-1.681.09-2.95-1.1692.97
177 SAP30BP | E10_Aa | (PostTx) | (PreTx)2.04-1.083.81-1.1294.50
178 MBD1 | E4_Da | (PostTx) | (PreTx)1.541.083.14N/A93.78
179 PAQR3 | E10_Da | (PostTx) | (PreTx)-2.381.08-4.83-1.1095.42
180 EIF4ENIF1 | E13_Db | (PostTx) | (PreTx)1.401.072.84N/A93.59
181 FAM176B | E1_Da | (PostTx) | (PreTx)2.67-1.075.97-1.0896.40
182 USP21 | E11_Aa | (PostTx) | (PreTx)2.15-1.074.14-1.1095.58
183 CDC42SE1 | E3_Da | (PostTx) | (PreTx)1.701.073.48N/A95.01
184 FAM36A | E3_Aa | (PostTx) | (PreTx)1.76-1.073.18-1.1294.69
185 RP11-345P4.4 | E7_Da | (PostTx) | (PreTx)1.581.073.18N/A94.71
186 ZNF207 | E2_Da | (PostTx) | (PreTx)-1.781.07-3.21-1.1294.78
187 BTN2A2 | E1_Da | (PostTx) | (PreTx)-1.39-1.06-2.78N/A94.41
188 SFRS12 | E4_Da | (PostTx) | (PreTx)2.88-1.066.96-1.0697.06
189 ANKRD37 | E5_Aa | (PostTx) | (PreTx)-2.431.06-5.06-1.0896.51
190 DGKA | E12_Da | (PostTx) | (PreTx)1.491.042.93N/A96.53
191 NUP85 | E17_Da | (PostTx) | (PreTx)1.83-1.043.44-1.0697.19
192 QRICH1 | E8_Da | (PostTx) | (PreTx)1.401.032.72N/A97.21
193 ZRANB3 | E25_Aa | (PostTx) | (PreTx)-1.38-1.03-2.68N/A97.22
194 NOP16 | E2_Da | (PostTx) | (PreTx)-1.201.03-2.25-1.0696.97
195 SAT1 | E3_Aa | (PostTx) | (PreTx)1.49-1.022.77-1.0398.44
196 DEPDC5 | E38_Da | (PostTx) | (PreTx)1.761.023.45N/A98.73
197 LIME1 | E3_Da | (PostTx) | (PreTx)-1.94-1.01-3.90N/A99.00
198 CD47 | E7_Da | (PostTx) | (PreTx)2.23-1.014.64-1.0299.20
199 BTN3A3 | E4_Aa | (PostTx) | (PreTx)2.44-1.015.35-1.0199.33
200 SYMPK | E2_Aa | (PostTx) | (PreTx)2.961.017.86N/A99.57
201 JAK3 | E13_Da | (PostTx) | (PreTx)1.44-1.002.71-1.0199.64
202 SNAPC5 | E4_Aa | (PostTx) | (PreTx)-1.431.00-2.69-1.0199.69
203 NARF | E12_Aa | (PostTx) | (PreTx)2.50-1.005.66-1.0099.87
204 ACADVL | E11_Aa | (PostTx) | (PreTx)1.541.002.92N/A99.86