Alternative expression values of the type: NovelBoundary for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: NovelBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelBoundary features

The following table provides a ranked list of alternatively expressed NovelBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 CST3 | E2_Ac | (PostTx) | (PreTx)-2.18-6.76-30.68N/A64.18
2 COL6A3 | E2_Ab | (PostTx) | (PreTx)-1.14-8.52-18.76N/A57.78
3 ALKBH6 | E7_Aa | (PostTx) | (PreTx)2.901.6011.93N/A83.99
4 NEIL1 | E5_Da | (PostTx) | (PreTx)1.643.5311.00N/A65.55
5 FADS3 | E2_Aa | (PostTx) | (PreTx)1.154.5710.13N/A60.38
6 HECW2 | E28_Aa | (PostTx) | (PreTx)3.42-1.149.45-1.1294.61
7 WBP1 | E2_Aa | (PostTx) | (PreTx)2.701.409.12N/A86.75
8 PTOV1 | E10_Aa | (PostTx) | (PreTx)3.011.118.95N/A95.54
9 AC069281.6 | E4_Aa | (PostTx) | (PreTx)1.303.628.94N/A62.98
10 RERE | E23_Aa | (PostTx) | (PreTx)2.851.188.48N/A92.93
11 DMAP1 | E6_Aa | (PostTx) | (PreTx)2.671.338.46N/A88.32
12 NME3 | E2_Da | (PostTx) | (PreTx)2.381.578.18N/A82.39
13 ZDHHC8 | E5_Aa | (PostTx) | (PreTx)2.691.237.96N/A90.86
14 SYMPK | E2_Aa | (PostTx) | (PreTx)2.961.017.86N/A99.57
15 WASH4P | E2_Aa | (PostTx) | (PreTx)1.572.627.81N/A68.08
16 NCR3 | E5_Da | (PostTx) | (PreTx)-1.50-2.71-7.65N/A67.12
17 FCHSD1 | E19_Aa | (PostTx) | (PreTx)2.011.857.46N/A76.53
18 CRELD2 | E10_Aa | (PostTx) | (PreTx)3.12-1.177.46-1.1792.81
19 NR2F2 | E2_Aa | (PostTx) | (PreTx)-1.27-3.05-7.39N/A64.18
20 ARSA | E2_Da | (PostTx) | (PreTx)2.251.537.24N/A82.41
21 MMS19 | E8_Aa | (PostTx) | (PreTx)2.661.157.24N/A93.48
22 HSH2D | E5_Aa | (PostTx) | (PreTx)1.822.027.13N/A73.64
23 CD40 | E4_Dc | (PostTx) | (PreTx)1.722.157.06N/A71.90
24 DOM3Z | E2_Da | (PostTx) | (PreTx)2.151.576.96N/A81.06
25 PHKA2 | E29_Da | (PostTx) | (PreTx)2.271.456.96N/A84.03
26 SFRS12 | E4_Da | (PostTx) | (PreTx)2.88-1.066.96-1.0697.06
27 CLK2 | E3_Da | (PostTx) | (PreTx)1.662.126.71N/A71.71
28 FBXO44 | E6_Aa | (PostTx) | (PreTx)1.682.066.61N/A72.36
29 PTCD3 | E19_Da | (PostTx) | (PreTx)2.321.306.47N/A87.71
30 CARKD | E10_Da | (PostTx) | (PreTx)2.241.376.47N/A85.51
31 MSTO1 | E7_Da | (PostTx) | (PreTx)2.101.516.47N/A81.85
32 APBB3 | E2_Aa | (PostTx) | (PreTx)1.212.796.47N/A64.50
33 CAMK1 | E10_Aa | (PostTx) | (PreTx)2.531.126.47N/A94.41
34 TARBP1 | E24_Aa | (PostTx) | (PreTx)2.451.196.47N/A91.62
35 SPSB3 | E4_Aa | (PostTx) | (PreTx)2.041.566.43N/A80.75
36 NDUFB8 | E5_Aa | (PostTx) | (PreTx)2.431.176.29N/A92.29
37 RP5-1077B9.4 | E6_Da | (PostTx) | (PreTx)2.351.236.29N/A89.82
38 TAF11 | E4_Da | (PostTx) | (PreTx)1.811.806.29N/A75.86
39 KIAA0586 | E2_Aa | (PostTx) | (PreTx)-2.17-1.38-6.23N/A85.06
40 AC073264.5 | E1_Da | (PostTx) | (PreTx)-1.19-2.68-6.10N/A64.70
41 DHRS4 | E1_Da | (PostTx) | (PreTx)-2.42-1.13-6.09N/A93.46
42 SNX22 | E2_Da | (PostTx) | (PreTx)1.402.275.98N/A68.62
43 KLRK1 | E12_Aa | (PostTx) | (PreTx)1.601.975.98N/A72.46
44 FBRSL1 | E2_Aa | (PostTx) | (PreTx)1.931.575.98N/A79.96
45 FAM176B | E1_Da | (PostTx) | (PreTx)2.67-1.075.97-1.0896.40
46 CTNND1 | E22_Da | (PostTx) | (PreTx)3.44-1.825.97-2.0074.94
47 RNF166 | E2_Da | (PostTx) | (PreTx)2.72-1.105.97-1.1194.92
48 ZNF789 | E4_Da | (PostTx) | (PreTx)1.711.825.97N/A74.91
49 H3F3A | E5_Aa | (PostTx) | (PreTx)2.231.275.96N/A88.04
50 C21orf66 | E7_Da | (PostTx) | (PreTx)1.891.615.96N/A78.93
51 SYNE2 | E116_Aa | (PostTx) | (PreTx)3.54-1.965.93-2.2272.57
52 ANKZF1 | E9_Da | (PostTx) | (PreTx)1.651.835.75N/A74.29
53 SLC9A3R2 | E7_Aa | (PostTx) | (PreTx)-1.13-2.63-5.74N/A64.39
54 AC106782.5 | E13_Da | (PostTx) | (PreTx)-2.921.33-5.71-1.3986.06
55 NARF | E12_Aa | (PostTx) | (PreTx)2.50-1.005.66-1.0099.87
56 COG1 | E13_Da | (PostTx) | (PreTx)2.65-1.115.66-1.1294.47
57 ID2 | E3_Da | (PostTx) | (PreTx)2.75-1.195.66-1.2290.99
58 POLM | E7_Da | (PostTx) | (PreTx)2.071.355.66N/A85.20
59 NPEPPS | E22_Aa | (PostTx) | (PreTx)2.70-1.155.66-1.1792.70
60 MICAL2 | E26_Db | (PostTx) | (PreTx)-1.34-2.23-5.65N/A68.30
61 AP000872.5 | E17_Da | (PostTx) | (PreTx)-1.14-2.55-5.63N/A64.84
62 OGT | E4_Da | (PostTx) | (PreTx)1.571.885.58N/A73.09
63 OAT | E2_Ab | (PostTx) | (PreTx)-1.51-1.95-5.52N/A71.98
64 STAT2 | E7_Aa | (PostTx) | (PreTx)2.241.155.44N/A92.45
65 TAZ | E6_Da | (PostTx) | (PreTx)1.801.535.35N/A79.66
66 WDR45 | E7_Dd | (PostTx) | (PreTx)2.091.265.35N/A88.06
67 BTN3A3 | E4_Aa | (PostTx) | (PreTx)2.44-1.015.35-1.0199.33
68 FBXO9 | E10_Da | (PostTx) | (PreTx)1.841.505.35N/A80.62
69 HEXDC | E9_Da | (PostTx) | (PreTx)1.771.565.35N/A78.95
70 NPAL2 | E10_Aa | (PostTx) | (PreTx)1.811.525.35N/A79.92
71 TOP3B | E19_Aa | (PostTx) | (PreTx)1.631.725.33N/A75.50
72 SLC29A1 | E2_Ad | (PostTx) | (PreTx)-1.39-2.02-5.28N/A70.28
73 PAN2 | E23_Da | (PostTx) | (PreTx)1.501.865.26N/A72.81
74 TMEM55B | E3_Aa | (PostTx) | (PreTx)1.951.365.25N/A84.41
75 SH3GLB2 | E8_Da | (PostTx) | (PreTx)1.581.745.22N/A74.82
76 RASGRP3 | E15_Da | (PostTx) | (PreTx)1.611.705.21N/A75.61
77 PHLDB1 | E2_Ab | (PostTx) | (PreTx)-1.17-2.29-5.15N/A66.41
78 TSPAN14 | E14_Aa | (PostTx) | (PreTx)-1.38-1.97-5.11N/A70.63
79 CDK5RAP3 | E6_Aa | (PostTx) | (PreTx)1.531.765.11N/A74.18
80 TIAL1 | E11_Aa | (PostTx) | (PreTx)1.941.335.10N/A85.04
81 GABPB1 | E1_Da | (PostTx) | (PreTx)2.55-1.165.09-1.1991.85
82 C6orf192 | E9_Da | (PostTx) | (PreTx)-1.76-1.50-5.06N/A80.07
83 NPHP3 | E19_Aa | (PostTx) | (PreTx)-3.532.28-5.06-3.0666.34
84 ANKRD37 | E5_Aa | (PostTx) | (PreTx)-2.431.06-5.06-1.0896.51
85 WDR42A | E3_Aa | (PostTx) | (PreTx)2.111.185.06N/A90.95
86 DGKZ | E28_Da | (PostTx) | (PreTx)1.991.275.06N/A87.09
87 C21orf66 | E8_Da | (PostTx) | (PreTx)1.641.615.03N/A77.24
88 DMAP1 | E5_Da | (PostTx) | (PreTx)1.921.335.03N/A85.13
89 ZNF655 | E6_Aa | (PostTx) | (PreTx)2.151.135.03N/A92.89
90 RELT | E8_Aa | (PostTx) | (PreTx)1.851.405.03N/A82.90
91 CHKB | E7_Aa | (PostTx) | (PreTx)1.122.284.94N/A65.96
92 CHKB | E2_Aa | (PostTx) | (PreTx)1.082.284.83N/A65.65
93 PAQR3 | E10_Da | (PostTx) | (PreTx)-2.381.08-4.83-1.1095.42
94 USP9X | E6_Ab | (PostTx) | (PreTx)-1.32-1.93-4.82N/A70.51
95 EPHX1 | E9_Da | (PostTx) | (PreTx)4.09-3.614.72-10.5754.73
96 METT11D1 | E9_Da | (PostTx) | (PreTx)1.162.114.72N/A67.44
97 PRPF39 | E5_Aa | (PostTx) | (PreTx)1.371.834.71N/A72.00
98 CCDC88A | E30_Aa | (PostTx) | (PreTx)1.841.324.71N/A84.91
99 CD47 | E7_Da | (PostTx) | (PreTx)2.23-1.014.64-1.0299.20
100 TOP3B | E17_Da | (PostTx) | (PreTx)1.421.724.60N/A73.76
101 EXOSC8 | E5_Aa | (PostTx) | (PreTx)1.881.254.60N/A87.33
102 NIPBL | E46_Da | (PostTx) | (PreTx)-1.50-1.62-4.60N/A75.96
103 TAF1C | E11_Da | (PostTx) | (PreTx)1.002.294.60N/A64.75
104 METTL3 | E8_Da | (PostTx) | (PreTx)1.661.454.56N/A80.43
105 WDR39 | E6_Aa | (PostTx) | (PreTx)2.47-1.224.53-1.3188.31
106 HLA-F | E3_Aa | (PostTx) | (PreTx)1.991.144.51N/A92.09
107 VMA21 | E3_Aa | (PostTx) | (PreTx)-1.77-1.32-4.49N/A84.49
108 TAZ | E8_Aa | (PostTx) | (PreTx)1.511.534.37N/A77.50
109 C17orf65 | E3_Da | (PostTx) | (PreTx)1.801.264.37N/A86.58
110 CCS | E4_Aa | (PostTx) | (PreTx)1.531.504.35N/A78.34
111 SEC14L1 | E1_Da | (PostTx) | (PreTx)-1.30-1.75-4.31N/A72.29
112 CEPT1 | E10_Aa | (PostTx) | (PreTx)-1.94-1.12-4.29N/A92.98
113 SFRS7 | E6_Aa | (PostTx) | (PreTx)1.661.344.24N/A83.10
114 RHOT2 | E11_Aa | (PostTx) | (PreTx)1.211.834.21N/A70.48
115 AP1GBP1 | E1_Da | (PostTx) | (PreTx)-1.34-1.67-4.21N/A73.77
116 TBRG1 | E4_Aa | (PostTx) | (PreTx)1.721.274.17N/A85.76
117 CAMK1 | E9_Da | (PostTx) | (PreTx)1.891.124.14N/A92.78
118 USP21 | E11_Aa | (PostTx) | (PreTx)2.15-1.074.14-1.1095.58
119 TMEM140 | E2_Aa | (PostTx) | (PreTx)-1.04-2.01-4.12N/A66.98
120 DGKD | E12_Da | (PostTx) | (PreTx)2.18-1.134.04-1.1992.18
121 N4BP2L2 | E5_Aa | (PostTx) | (PreTx)1.361.523.91N/A76.51
122 FOSB | E4_Aa | (PostTx) | (PreTx)-1.027.923.91N/A39.72
123 DYNC1LI2 | E7_Da | (PostTx) | (PreTx)2.14-1.133.91-1.1991.97
124 CCDC49 | E5_Da | (PostTx) | (PreTx)1.801.123.91N/A92.27
125 PHF20 | E12_Da | (PostTx) | (PreTx)-1.14-1.77-3.90N/A70.52
126 LIME1 | E3_Da | (PostTx) | (PreTx)-1.94-1.01-3.90N/A99.00
127 STK25 | E6_Aa | (PostTx) | (PreTx)1.661.233.89N/A86.85
128 TRPT1 | E5_Da | (PostTx) | (PreTx)1.291.593.89N/A74.41
129 SAP30BP | E10_Aa | (PostTx) | (PreTx)2.04-1.083.81-1.1294.50
130 SDR39U1 | E3_Aa | (PostTx) | (PreTx)1.461.383.81N/A80.49
131 ANKZF1 | E10_Da | (PostTx) | (PreTx)1.051.833.80N/A68.81
132 GUK1 | E8_Ab | (PostTx) | (PreTx)-2.211.22-3.77-1.3686.83
133 C9orf78 | E8_Ab | (PostTx) | (PreTx)-1.28-1.54-3.75N/A75.41
134 TRA2A | E2_Aa | (PostTx) | (PreTx)1.551.273.73N/A84.53
135 ZNF296 | E2_Da | (PostTx) | (PreTx)1.651.173.68N/A89.15
136 FAM38A | E37_Aa | (PostTx) | (PreTx)2.54-1.583.68-2.0874.04
137 SPSB3 | E5_Da | (PostTx) | (PreTx)1.241.563.68N/A74.61
138 PRAMEL | E2_Da | (PostTx) | (PreTx)1.201.603.68N/A73.55
139 HNRPDL | E7_Da | (PostTx) | (PreTx)1.701.133.67N/A91.31
140 CYTH1 | E14_Aa | (PostTx) | (PreTx)1.99-1.093.66-1.1493.93
141 DDX54 | E18_Ab | (PostTx) | (PreTx)-1.56-1.24-3.65N/A85.87
142 FANCL | E13_Aa | (PostTx) | (PreTx)-2.481.53-3.64-1.9975.11
143 CAMK1 | E3_Aa | (PostTx) | (PreTx)1.701.123.63N/A92.09
144 ANO9 | E22_Aa | (PostTx) | (PreTx)1.241.543.63N/A75.03
145 AC145132.2 | E2_Aa | (PostTx) | (PreTx)-1.67-1.13-3.61N/A91.12
146 USP34 | E80_Aa | (PostTx) | (PreTx)2.59-1.673.59-2.3571.26
147 CDK5RAP3 | E5_Da | (PostTx) | (PreTx)1.021.763.58N/A69.19
148 PTOV1 | E9_Da | (PostTx) | (PreTx)1.691.113.57N/A92.56
149 GGA2 | E4_Aa | (PostTx) | (PreTx)1.321.423.52N/A78.37
150 CDC42SE1 | E3_Da | (PostTx) | (PreTx)1.701.073.48N/A95.01
151 ZBTB48 | E5_Aa | (PostTx) | (PreTx)1.121.593.45N/A72.80
152 DEPDC5 | E38_Da | (PostTx) | (PreTx)1.761.023.45N/A98.73
153 MSL3L1 | E9_Aa | (PostTx) | (PreTx)1.411.303.45N/A82.64
154 NUP85 | E17_Da | (PostTx) | (PreTx)1.83-1.043.44-1.0697.19
155 DTNB | E15_Da | (PostTx) | (PreTx)1.571.133.35N/A90.81
156 SLC3A2 | E5_Aa | (PostTx) | (PreTx)-1.09-1.57-3.33N/A72.77
157 ILF3 | E12_Aa | (PostTx) | (PreTx)1.421.233.31N/A85.09
158 C3orf63 | E18_Aa | (PostTx) | (PreTx)-1.02-1.62-3.28N/A71.18
159 ZNF207 | E2_Da | (PostTx) | (PreTx)-1.781.07-3.21-1.1294.78
160 FAM36A | E3_Aa | (PostTx) | (PreTx)1.76-1.073.18-1.1294.69
161 RP11-345P4.4 | E7_Da | (PostTx) | (PreTx)1.581.073.18N/A94.71
162 SFRS5 | E5_Db | (PostTx) | (PreTx)1.031.553.18N/A72.36
163 WDR81 | E4_Ab | (PostTx) | (PreTx)-1.08-1.49-3.17N/A74.18
164 DLG1 | E11_Db | (PostTx) | (PreTx)-1.44-1.17-3.16N/A88.22
165 HNRNPH1 | E5_Aa | (PostTx) | (PreTx)1.441.163.16N/A88.42
166 MBD1 | E4_Da | (PostTx) | (PreTx)1.541.083.14N/A93.78
167 ISGF3G | E18_Da | (PostTx) | (PreTx)1.401.193.14N/A86.62
168 WDR6 | E3_Aa | (PostTx) | (PreTx)1.341.223.08N/A85.11
169 HNRPDL | E8_Aa | (PostTx) | (PreTx)1.441.133.08N/A90.10
170 TAP2 | E5_Da | (PostTx) | (PreTx)1.301.243.07N/A83.70
171 ANKRD10 | E5_Da | (PostTx) | (PreTx)1.221.313.05N/A80.37
172 IL2RA | E4_Da | (PostTx) | (PreTx)-1.13-1.38-3.01N/A77.45
173 ASXL1 | E10_Aa | (PostTx) | (PreTx)1.311.223.01N/A84.94
174 AC023024.6 | E6_Db | (PostTx) | (PreTx)-1.07-1.43-2.99N/A75.51
175 BRD9 | E4_Da | (PostTx) | (PreTx)-1.681.09-2.95-1.1692.97
176 DGKA | E12_Da | (PostTx) | (PreTx)1.491.042.93N/A96.53
177 ACADVL | E11_Aa | (PostTx) | (PreTx)1.541.002.92N/A99.86
178 PTOV1 | E9_Aa | (PostTx) | (PreTx)1.381.112.88N/A91.20
179 EIF4ENIF1 | E13_Db | (PostTx) | (PreTx)1.401.072.84N/A93.59
180 SDR39U1 | E6_Da | (PostTx) | (PreTx)-1.951.38-2.79-1.9275.98
181 BTN2A2 | E1_Da | (PostTx) | (PreTx)-1.39-1.06-2.78N/A94.41
182 KIAA0323 | E2_Da | (PostTx) | (PreTx)1.76-1.222.77-1.4983.47
183 SAT1 | E3_Aa | (PostTx) | (PreTx)1.49-1.022.77-1.0398.44
184 CALCOCO1 | E16_Aa | (PostTx) | (PreTx)1.171.212.72N/A84.24
185 QRICH1 | E8_Da | (PostTx) | (PreTx)1.401.032.72N/A97.21
186 JAK3 | E13_Da | (PostTx) | (PreTx)1.44-1.002.71-1.0199.64
187 TRAP1 | E17_Aa | (PostTx) | (PreTx)1.76-1.252.70-1.5981.41
188 CRTC2 | E8_Aa | (PostTx) | (PreTx)1.281.112.70N/A90.28
189 SNAPC5 | E4_Aa | (PostTx) | (PreTx)-1.431.00-2.69-1.0199.69
190 ZRANB3 | E25_Aa | (PostTx) | (PreTx)-1.38-1.03-2.68N/A97.22
191 HNRNPH1 | E3_Da | (PostTx) | (PreTx)1.201.162.67N/A86.67
192 YTHDC1 | E14_Aa | (PostTx) | (PreTx)1.90-1.402.66-2.0674.33
193 KCNMB3 | E2_Da | (PostTx) | (PreTx)-1.631.19-2.60-1.4484.66
194 EXOC7 | E6_Db | (PostTx) | (PreTx)1.52-1.132.54-1.3088.45
195 GAK | E1_Da | (PostTx) | (PreTx)-1.03-1.23-2.53N/A81.48
196 FAM18A | E8_Aa | (PostTx) | (PreTx)-1.791.38-2.51-2.0874.07
197 AGXT2L2 | E11_Db | (PostTx) | (PreTx)-2.091.70-2.51-3.7463.39
198 C3orf10 | E4_Aa | (PostTx) | (PreTx)-1.531.17-2.48-1.4085.59
199 HECW2 | E29_Aa | (PostTx) | (PreTx)1.48-1.142.45-1.3387.51
200 HNRNPH1 | E2_Da | (PostTx) | (PreTx)1.051.162.40N/A85.32
201 STUB1 | E6_Aa | (PostTx) | (PreTx)-1.02-1.18-2.40N/A83.76
202 PHF10 | E11_Da | (PostTx) | (PreTx)-1.371.15-2.25-1.4185.53
203 NOP16 | E2_Da | (PostTx) | (PreTx)-1.201.03-2.25-1.0696.97
204 CFLAR | E7_Da | (PostTx) | (PreTx)1.30-1.112.23-1.2988.75