Alternative expression values of the type: Intron for comparison: DLBCL_vs_FL (abs(SI) value > 2)


Distribution of log2 SI values for comparison: DLBCL_vs_FL and data type: Intron

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: Intron. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed Intron features

The following table provides a ranked list of alternatively expressed Intron features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKDLBCL_vs_FL (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 ACADVL | I10 | (DLBCL) | (FL)-4.961.31-23.77-1.1992.16
2 FADS3 | I8 | (DLBCL) | (FL)-3.81-1.50-20.98N/A88.29
3 C17orf62 | I2 | (DLBCL) | (FL)-3.491.23-9.15-1.2191.46
4 CDK5RAP3 | I7 | (DLBCL) | (FL)-3.41-1.18-12.48N/A93.94
5 SNRNP70 | I8 | (DLBCL) | (FL)-3.39-1.13-11.86N/A95.35
6 UBA7 | I12 | (DLBCL) | (FL)-3.38-1.10-11.52N/A96.14
7 ZNF266 | I6 | (DLBCL) | (FL)-3.261.06-9.02-1.0697.32
8 C16orf58 | I9 | (DLBCL) | (FL)-3.251.11-8.53-1.1195.19
9 SFRS5 | I5 | (DLBCL) | (FL)-3.151.18-7.53-1.1892.49
10 ELAVL1 | I1 | (DLBCL) | (FL)3.141.2310.81N/A92.04
11 TYK2 | I18 | (DLBCL) | (FL)-3.13-1.50-13.13N/A86.35
12 AP1G2 | I4 | (DLBCL) | (FL)-3.12-1.26-10.97N/A91.08
13 CDK10 | I9 | (DLBCL) | (FL)-3.051.01-8.24-1.0199.60
14 CDK10 | I8 | (DLBCL) | (FL)-3.051.01-8.23-1.0199.60
15 METT11D1 | I9 | (DLBCL) | (FL)-3.041.13-7.27-1.1394.21
16 DDX17 | I11 | (DLBCL) | (FL)-3.00-1.31-10.43N/A89.76
17 ANKZF1 | I10 | (DLBCL) | (FL)-3.00-1.05-8.35N/A97.88
18 CDK5RAP3 | I5 | (DLBCL) | (FL)-2.96-1.18-9.18N/A93.16
19 AP1G2 | I16 | (DLBCL) | (FL)-2.96-1.26-9.84N/A90.69
20 ZNF266 | I7 | (DLBCL) | (FL)-2.921.06-7.13-1.0697.00
21 DDX17 | I12 | (DLBCL) | (FL)-2.90-1.31-9.76N/A89.50
22 DDX5 | I11 | (DLBCL) | (FL)-2.88-1.03-7.58N/A98.57
23 WDR45 | I7 | (DLBCL) | (FL)-2.861.19-6.09-1.2291.05
24 COQ4 | I5 | (DLBCL) | (FL)-2.851.13-6.40-1.1493.89
25 TCIRG1 | I5 | (DLBCL) | (FL)-2.82-1.24-8.77N/A90.90
26 CXXC1 | I11 | (DLBCL) | (FL)-2.81-1.15-8.11N/A93.57
27 PH-4 | I6 | (DLBCL) | (FL)-2.80-1.10-7.66N/A95.48
28 C19orf6 | I4 | (DLBCL) | (FL)-2.80-1.45-10.04N/A86.21
29 SH3GLB2 | I8 | (DLBCL) | (FL)-2.791.09-6.31-1.1095.34
30 ANKZF1 | I9 | (DLBCL) | (FL)-2.76-1.05-7.11N/A97.71
31 C5orf45 | I7 | (DLBCL) | (FL)-2.761.49-4.53-1.7279.01
32 SGSM3 | I19 | (DLBCL) | (FL)-2.70-1.19-7.74N/A92.00
33 METRN | I3 | (DLBCL) | (FL)2.681.388.85N/A87.10
34 ACADVL | I9 | (DLBCL) | (FL)-2.671.31-4.85-1.4185.42
35 PTPN1L | I3 | (DLBCL) | (FL)2.66-1.006.31-1.0099.92
36 CCS | I3 | (DLBCL) | (FL)-2.661.07-5.89-1.0896.29
37 IFFO1 | I8 | (DLBCL) | (FL)-2.64-1.24-7.74N/A90.54
38 SYTL1 | I10 | (DLBCL) | (FL)-2.611.10-5.52-1.1294.52
39 AC010422.7 | I3 | (DLBCL) | (FL)-2.601.30-4.68-1.4185.45
40 AGAP2 | I18 | (DLBCL) | (FL)2.60-1.105.53-1.1194.92
41 VAMP2 AC129492.6 | Ix | (DLBCL) | (FL)-2.581.55-3.86-1.9675.52
42 ZMIZ2 | I8 | (DLBCL) | (FL)-2.58-1.41-8.41N/A86.06
43 MAN2C1 | I19 | (DLBCL) | (FL)-2.55-1.15-6.72N/A93.17
44 ZNF276 | I7 | (DLBCL) | (FL)2.52-1.274.49-1.3886.17
45 AL032819.32 | I4 | (DLBCL) | (FL)2.49-1.204.67-1.2789.29
46 SFRS7 | I3 | (DLBCL) | (FL)-2.461.22-4.54-1.3088.59
47 SLC39A13 | I6 | (DLBCL) | (FL)-2.451.20-4.55-1.2889.16
48 AC010422.7 | I5 | (DLBCL) | (FL)-2.431.30-4.15-1.4584.41
49 CYTH1 | I13 | (DLBCL) | (FL)-2.42-1.08-5.78N/A95.92
50 SFRS7 | I4 | (DLBCL) | (FL)-2.421.22-4.40-1.3088.38
51 KCNN4 | I6 | (DLBCL) | (FL)-2.411.10-4.82-1.1394.25
52 CUL9 | I34 | (DLBCL) | (FL)2.41-1.822.91-3.5664.05
53 BAT1 | I9 | (DLBCL) | (FL)-2.37-1.07-5.53N/A96.24
54 GALT | I4 | (DLBCL) | (FL)-2.331.21-4.18-1.3088.34
55 ANKZF1 | I11 | (DLBCL) | (FL)-2.24-1.05-4.93N/A97.20
56 SFRS14 | I9 | (DLBCL) | (FL)-2.23-1.64-7.66N/A80.53
57 AP1G2 | I15 | (DLBCL) | (FL)-2.22-1.26-5.91N/A88.33
58 RPL9 | I1 | (DLBCL) | (FL)-2.2216.153.46N/A30.86
59 ANO9 | I19 | (DLBCL) | (FL)-2.22-1.18-5.51N/A91.02
60 DHFRL1 | I1 | (DLBCL) | (FL)2.211.064.93N/A96.21
61 AKAP8L | I9 | (DLBCL) | (FL)-2.21-1.08-4.98N/A95.57
62 EZH1 | I19 | (DLBCL) | (FL)-2.20-1.38-6.35N/A85.14
63 C11orf83 | I1 | (DLBCL) | (FL)2.181.014.59N/A99.19
64 FCRL2 | I5 | (DLBCL) | (FL)-2.17-2.08-9.34N/A75.31
65 METTL3 | I9 | (DLBCL) | (FL)-2.16-1.76-7.87N/A78.55
66 ILF3 | I11 | (DLBCL) | (FL)-2.16-1.25-5.59N/A88.49
67 ARF1GAP | I9 | (DLBCL) | (FL)-2.15-1.08-4.82N/A95.22
68 BTNL9 | I10 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.06
69 BTNL9 | I11 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.05
70 ATP8B1 | I17 | (DLBCL) | (FL)2.14-1.443.06-1.9675.57
71 IKBKB | I15 | (DLBCL) | (FL)-2.13-1.08-4.76N/A95.09
72 LRCH4 | I17 | (DLBCL) | (FL)-2.101.02-4.20-1.0398.44
73 ZNF76 | I9 | (DLBCL) | (FL)-2.10-1.16-4.99N/A91.41
74 TMC6 | I2 | (DLBCL) | (FL)-2.09-1.09-4.63N/A94.69
75 VPS52 | I14 | (DLBCL) | (FL)-2.08-1.08-4.56N/A95.38
76 ATG9B NOS3 | Ix | (DLBCL) | (FL)2.07-1.153.66-1.2490.20
77 CLK2 | I4 | (DLBCL) | (FL)-2.00-1.09-4.37N/A94.27
78 SLC6A16 | I2 | (DLBCL) | (FL)-1.99-1.26-5.00N/A87.52
79 PRPF39 | I3 | (DLBCL) | (FL)-1.99-1.34-5.33N/A85.10
80 SFRS1 | I3 | (DLBCL) | (FL)-1.991.08-3.69-1.1294.73
81 SFRS14 | I10 | (DLBCL) | (FL)-1.99-1.64-6.49N/A79.16
82 CAPN10 | I8 | (DLBCL) | (FL)-1.98-1.41-5.54N/A83.40
83 RP4-644F6.3 | I4 | (DLBCL) | (FL)1.971.345.27N/A85.01
84 CDC42SE1 C1orf56 | Ix | (DLBCL) | (FL)-1.96-1.12-4.36N/A92.65
85 SFRS6 | I3 | (DLBCL) | (FL)-1.951.05-3.68-1.0796.69
86 WDR42A | I12 | (DLBCL) | (FL)-1.941.06-3.61-1.1095.47
87 NEIL1 | I6 | (DLBCL) | (FL)-1.94-3.27-12.51N/A68.07
88 GBA2 | I12 | (DLBCL) | (FL)-1.93-1.20-4.59N/A89.28
89 SFRS7 | I5 | (DLBCL) | (FL)-1.921.22-3.12-1.4185.39
90 RNF6 | I1 | (DLBCL) | (FL)1.91-1.073.51-1.1294.75
91 CIITA | I22 | (DLBCL) | (FL)-1.91-1.82-6.80N/A76.27
92 CARD8 | I4 | (DLBCL) | (FL)-1.89-1.24-4.62N/A87.53
93 ARGLU1 | I4 | (DLBCL) | (FL)-1.88-1.62-5.94N/A78.76
94 LENG8 | I15 | (DLBCL) | (FL)-1.87-3.95-14.45N/A66.04
95 SLC25A28 | I2 | (DLBCL) | (FL)-1.861.19-3.05-1.3886.36
96 BTNL9 | I13 | (DLBCL) | (FL)-1.86-2.57-9.33N/A70.32
97 APBB3 | I8 | (DLBCL) | (FL)-1.86-2.30-8.32N/A71.83
98 PARP8 | I1 | (DLBCL) | (FL)1.821.093.84N/A94.12
99 RNF167 | I2 | (DLBCL) | (FL)1.772.016.88N/A73.37
100 CEP250 | I18 | (DLBCL) | (FL)-1.75-1.67-5.61N/A77.18
101 ACIN1 | I11 | (DLBCL) | (FL)-1.75-1.42-4.76N/A81.72
102 NFATC2IP | I3 | (DLBCL) | (FL)-1.74-1.06-3.55N/A95.42
103 RBM6 | I14 | (DLBCL) | (FL)-1.73-1.94-6.44N/A73.75
104 FCRL2 | I6 | (DLBCL) | (FL)-1.73-2.08-6.89N/A72.49
105 MYO19 | I25 | (DLBCL) | (FL)1.72-1.362.43-2.0674.27
106 TMEM41B | I7 | (DLBCL) | (FL)1.72-1.612.04-5.0259.97
107 CLK2 | I3 | (DLBCL) | (FL)-1.70-1.09-3.56N/A93.40
108 SLC29A2 | I9 | (DLBCL) | (FL)1.701.284.16N/A85.11
109 BTNL9 | I8 | (DLBCL) | (FL)-1.69-2.57-8.28N/A69.16
110 C17orf56 | I10 | (DLBCL) | (FL)-1.68-1.74-5.60N/A75.59
111 ZNF397 | I3 | (DLBCL) | (FL)1.65-1.332.35-2.0075.00
112 PRRT3 CRELD1 | Ix | (DLBCL) | (FL)1.631.183.65N/A88.59
113 AGAP2 | I17 | (DLBCL) | (FL)1.62-1.102.80-1.1991.84
114 HAAO | I8 | (DLBCL) | (FL)1.621.143.49N/A90.61
115 FOS | I3 | (DLBCL) | (FL)1.61-1.152.67-1.3287.89
116 MBD4 | I7 | (DLBCL) | (FL)-1.61-1.03-3.16N/A97.40
117 PSMB7 | I9 | (DLBCL) | (FL)-1.611.19-2.56-1.4684.35
118 CENPL | I1 | (DLBCL) | (FL)1.591.243.73N/A86.01
119 ARGLU1 | I3 | (DLBCL) | (FL)-1.59-1.62-4.85N/A76.68
120 ANKRD10 | I5 | (DLBCL) | (FL)-1.58-1.18-3.54N/A88.27
121 FNBP4 | I11 | (DLBCL) | (FL)-1.57-1.74-5.16N/A74.77
122 TM7SF2 | I2 | (DLBCL) | (FL)1.561.574.61N/A77.30
123 CHST11 | I1 | (DLBCL) | (FL)1.56-1.132.60-1.3088.55
124 CENPT | I8 | (DLBCL) | (FL)-1.55-1.67-4.89N/A75.51
125 RBM5 | I7 | (DLBCL) | (FL)-1.54-1.47-4.28N/A79.00
126 MSI2 | I14 | (DLBCL) | (FL)-1.54-1.61-4.68N/A76.37
127 NEIL1 | I5 | (DLBCL) | (FL)-1.54-3.27-9.49N/A65.51
128 AC084018.28 | I1 | (DLBCL) | (FL)1.53-1.232.35-1.6480.49
129 TFIP11 | I14 | (DLBCL) | (FL)1.521.103.16N/A92.08
130 OGT | I4 | (DLBCL) | (FL)-1.49-2.03-5.70N/A71.05
131 FCRL2 | I7 | (DLBCL) | (FL)-1.48-2.08-5.82N/A70.63
132 C17orf56 | I1 | (DLBCL) | (FL)-1.46-1.74-4.78N/A73.78
133 PAXIP1 | I20 | (DLBCL) | (FL)1.45-1.022.67-1.0497.89
134 HNRPDL | I7 | (DLBCL) | (FL)-1.441.13-2.41-1.3188.11
135 SNHG12 | I4 | (DLBCL) | (FL)-1.43-2.14-5.75N/A69.70
136 ATHL1 | I6 | (DLBCL) | (FL)-1.42-2.45-6.57N/A67.76
137 PILRB | I6 | (DLBCL) | (FL)-1.41-3.07-8.19N/A65.20
138 RP11-488L18.4 | I1 | (DLBCL) | (FL)-1.41-1.83-4.87N/A72.42
139 ANKH | I10 | (DLBCL) | (FL)-1.411.00-2.65-1.0199.65
140 SLC6A16 | I6 | (DLBCL) | (FL)-1.39-1.26-3.29N/A83.85
141 C11orf48 | I5 | (DLBCL) | (FL)1.391.193.11N/A86.66
142 HNRNPH1 | I4 | (DLBCL) | (FL)-1.39-1.18-3.08N/A87.21
143 ZNF688 | I4 | (DLBCL) | (FL)1.381.263.30N/A83.61
144 TBC1D10C | I1 | (DLBCL) | (FL)1.321.433.56N/A77.99
145 TCEA2 | I2 | (DLBCL) | (FL)1.311.523.78N/A76.00
146 POLD2 | I3 | (DLBCL) | (FL)1.291.202.94N/A85.66
147 IL17RB | I8 | (DLBCL) | (FL)-1.29-2.84-6.96N/A65.00
148 CARS | I21 | (DLBCL) | (FL)1.25-1.002.37-1.0199.64
149 ANKH | I9 | (DLBCL) | (FL)-1.241.00-2.36-1.0199.61
150 TMEM18 | I2 | (DLBCL) | (FL)1.231.613.77N/A73.69
151 APLNR | I1 | (DLBCL) | (FL)1.221.703.95N/A72.26
152 AC005071.2 PMS2L8 | Ix | (DLBCL) | (FL)1.201.152.63N/A87.70
153 TTC14 | I10 | (DLBCL) | (FL)-1.19-2.05-4.68N/A68.28
154 C1orf63 | I3 | (DLBCL) | (FL)-1.16-1.59-3.57N/A73.14
155 CHD3 | I38 | (DLBCL) | (FL)-1.16-1.71-3.83N/A71.36
156 TAF1C | I7 | (DLBCL) | (FL)-1.15-2.38-5.29N/A65.76
157 TUBGCP6 | I23 | (DLBCL) | (FL)-1.14-2.78-6.13N/A63.97
158 UBXN11 | I12 | (DLBCL) | (FL)-1.14-1.71-3.78N/A71.15
159 PCSK7 | I16 | (DLBCL) | (FL)1.141.042.29N/A95.55
160 CBLN3 | I1 | (DLBCL) | (FL)-1.11-1.93-4.17N/A68.43
161 CLK1 | I5 | (DLBCL) | (FL)-1.10-1.35-2.88N/A77.97
162 LDB1 | I10 | (DLBCL) | (FL)-1.071.01-2.09-1.0199.32
163 ZNF688 | I5 | (DLBCL) | (FL)1.061.262.64N/A80.59
164 ARTS-1 | I19 | (DLBCL) | (FL)1.051.102.28N/A89.62
165 FNDC8 NLE1 | Ix | (DLBCL) | (FL)1.041.122.31N/A88.13
166 CYR61 | I3 | (DLBCL) | (FL)-1.04-1.68-3.44N/A70.53
167 LENG8 | I16 | (DLBCL) | (FL)-1.03-3.95-8.09N/A60.35
168 RP4-644F6.3 | I3 | (DLBCL) | (FL)1.031.342.73N/A77.43
169 TTC14 | I11 | (DLBCL) | (FL)-1.01-2.05-4.13N/A66.42
170 NEIL1 | I5 | (DLBCL) | (FL)-1.01-3.27-6.58N/A61.39
171 C20orf198 | I1 | (DLBCL) | (FL)1.001.382.76N/A76.04
172 BTNL9 | I7 | (DLBCL) | (FL)-1.00-2.57-5.14N/A63.46