Alternative expression values of the type: Intron for comparison: DLBCL_vs_FL (abs(SI) value > 2)


Distribution of log2 SI values for comparison: DLBCL_vs_FL and data type: Intron

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: Intron. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed Intron features

The following table provides a ranked list of alternatively expressed Intron features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKDLBCL_vs_FL (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 ACADVL | I10 | (DLBCL) | (FL)-4.961.31-23.77-1.1992.16
2 FADS3 | I8 | (DLBCL) | (FL)-3.81-1.50-20.98N/A88.29
3 LENG8 | I15 | (DLBCL) | (FL)-1.87-3.95-14.45N/A66.04
4 TYK2 | I18 | (DLBCL) | (FL)-3.13-1.50-13.13N/A86.35
5 NEIL1 | I6 | (DLBCL) | (FL)-1.94-3.27-12.51N/A68.07
6 CDK5RAP3 | I7 | (DLBCL) | (FL)-3.41-1.18-12.48N/A93.94
7 SNRNP70 | I8 | (DLBCL) | (FL)-3.39-1.13-11.86N/A95.35
8 UBA7 | I12 | (DLBCL) | (FL)-3.38-1.10-11.52N/A96.14
9 BTNL9 | I10 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.06
10 BTNL9 | I11 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.05
11 AP1G2 | I4 | (DLBCL) | (FL)-3.12-1.26-10.97N/A91.08
12 ELAVL1 | I1 | (DLBCL) | (FL)3.141.2310.81N/A92.04
13 DDX17 | I11 | (DLBCL) | (FL)-3.00-1.31-10.43N/A89.76
14 C19orf6 | I4 | (DLBCL) | (FL)-2.80-1.45-10.04N/A86.21
15 AP1G2 | I16 | (DLBCL) | (FL)-2.96-1.26-9.84N/A90.69
16 DDX17 | I12 | (DLBCL) | (FL)-2.90-1.31-9.76N/A89.50
17 NEIL1 | I5 | (DLBCL) | (FL)-1.54-3.27-9.49N/A65.51
18 FCRL2 | I5 | (DLBCL) | (FL)-2.17-2.08-9.34N/A75.31
19 BTNL9 | I13 | (DLBCL) | (FL)-1.86-2.57-9.33N/A70.32
20 CDK5RAP3 | I5 | (DLBCL) | (FL)-2.96-1.18-9.18N/A93.16
21 C17orf62 | I2 | (DLBCL) | (FL)-3.491.23-9.15-1.2191.46
22 ZNF266 | I6 | (DLBCL) | (FL)-3.261.06-9.02-1.0697.32
23 METRN | I3 | (DLBCL) | (FL)2.681.388.85N/A87.10
24 TCIRG1 | I5 | (DLBCL) | (FL)-2.82-1.24-8.77N/A90.90
25 C16orf58 | I9 | (DLBCL) | (FL)-3.251.11-8.53-1.1195.19
26 ZMIZ2 | I8 | (DLBCL) | (FL)-2.58-1.41-8.41N/A86.06
27 ANKZF1 | I10 | (DLBCL) | (FL)-3.00-1.05-8.35N/A97.88
28 APBB3 | I8 | (DLBCL) | (FL)-1.86-2.30-8.32N/A71.83
29 BTNL9 | I8 | (DLBCL) | (FL)-1.69-2.57-8.28N/A69.16
30 CDK10 | I9 | (DLBCL) | (FL)-3.051.01-8.24-1.0199.60
31 CDK10 | I8 | (DLBCL) | (FL)-3.051.01-8.23-1.0199.60
32 PILRB | I6 | (DLBCL) | (FL)-1.41-3.07-8.19N/A65.20
33 CXXC1 | I11 | (DLBCL) | (FL)-2.81-1.15-8.11N/A93.57
34 LENG8 | I16 | (DLBCL) | (FL)-1.03-3.95-8.09N/A60.35
35 METTL3 | I9 | (DLBCL) | (FL)-2.16-1.76-7.87N/A78.55
36 SGSM3 | I19 | (DLBCL) | (FL)-2.70-1.19-7.74N/A92.00
37 IFFO1 | I8 | (DLBCL) | (FL)-2.64-1.24-7.74N/A90.54
38 PH-4 | I6 | (DLBCL) | (FL)-2.80-1.10-7.66N/A95.48
39 SFRS14 | I9 | (DLBCL) | (FL)-2.23-1.64-7.66N/A80.53
40 DDX5 | I11 | (DLBCL) | (FL)-2.88-1.03-7.58N/A98.57
41 SFRS5 | I5 | (DLBCL) | (FL)-3.151.18-7.53-1.1892.49
42 METT11D1 | I9 | (DLBCL) | (FL)-3.041.13-7.27-1.1394.21
43 ZNF266 | I7 | (DLBCL) | (FL)-2.921.06-7.13-1.0697.00
44 ANKZF1 | I9 | (DLBCL) | (FL)-2.76-1.05-7.11N/A97.71
45 IL17RB | I8 | (DLBCL) | (FL)-1.29-2.84-6.96N/A65.00
46 FCRL2 | I6 | (DLBCL) | (FL)-1.73-2.08-6.89N/A72.49
47 RNF167 | I2 | (DLBCL) | (FL)1.772.016.88N/A73.37
48 CIITA | I22 | (DLBCL) | (FL)-1.91-1.82-6.80N/A76.27
49 MAN2C1 | I19 | (DLBCL) | (FL)-2.55-1.15-6.72N/A93.17
50 NEIL1 | I5 | (DLBCL) | (FL)-1.01-3.27-6.58N/A61.39
51 ATHL1 | I6 | (DLBCL) | (FL)-1.42-2.45-6.57N/A67.76
52 SFRS14 | I10 | (DLBCL) | (FL)-1.99-1.64-6.49N/A79.16
53 RBM6 | I14 | (DLBCL) | (FL)-1.73-1.94-6.44N/A73.75
54 COQ4 | I5 | (DLBCL) | (FL)-2.851.13-6.40-1.1493.89
55 EZH1 | I19 | (DLBCL) | (FL)-2.20-1.38-6.35N/A85.14
56 SH3GLB2 | I8 | (DLBCL) | (FL)-2.791.09-6.31-1.1095.34
57 PTPN1L | I3 | (DLBCL) | (FL)2.66-1.006.31-1.0099.92
58 TUBGCP6 | I23 | (DLBCL) | (FL)-1.14-2.78-6.13N/A63.97
59 WDR45 | I7 | (DLBCL) | (FL)-2.861.19-6.09-1.2291.05
60 ARGLU1 | I4 | (DLBCL) | (FL)-1.88-1.62-5.94N/A78.76
61 AP1G2 | I15 | (DLBCL) | (FL)-2.22-1.26-5.91N/A88.33
62 CCS | I3 | (DLBCL) | (FL)-2.661.07-5.89-1.0896.29
63 FCRL2 | I7 | (DLBCL) | (FL)-1.48-2.08-5.82N/A70.63
64 CYTH1 | I13 | (DLBCL) | (FL)-2.42-1.08-5.78N/A95.92
65 SNHG12 | I4 | (DLBCL) | (FL)-1.43-2.14-5.75N/A69.70
66 OGT | I4 | (DLBCL) | (FL)-1.49-2.03-5.70N/A71.05
67 CEP250 | I18 | (DLBCL) | (FL)-1.75-1.67-5.61N/A77.18
68 C17orf56 | I10 | (DLBCL) | (FL)-1.68-1.74-5.60N/A75.59
69 ILF3 | I11 | (DLBCL) | (FL)-2.16-1.25-5.59N/A88.49
70 CAPN10 | I8 | (DLBCL) | (FL)-1.98-1.41-5.54N/A83.40
71 BAT1 | I9 | (DLBCL) | (FL)-2.37-1.07-5.53N/A96.24
72 AGAP2 | I18 | (DLBCL) | (FL)2.60-1.105.53-1.1194.92
73 SYTL1 | I10 | (DLBCL) | (FL)-2.611.10-5.52-1.1294.52
74 ANO9 | I19 | (DLBCL) | (FL)-2.22-1.18-5.51N/A91.02
75 PRPF39 | I3 | (DLBCL) | (FL)-1.99-1.34-5.33N/A85.10
76 TAF1C | I7 | (DLBCL) | (FL)-1.15-2.38-5.29N/A65.76
77 RP4-644F6.3 | I4 | (DLBCL) | (FL)1.971.345.27N/A85.01
78 FNBP4 | I11 | (DLBCL) | (FL)-1.57-1.74-5.16N/A74.77
79 BTNL9 | I7 | (DLBCL) | (FL)-1.00-2.57-5.14N/A63.46
80 SLC6A16 | I2 | (DLBCL) | (FL)-1.99-1.26-5.00N/A87.52
81 ZNF76 | I9 | (DLBCL) | (FL)-2.10-1.16-4.99N/A91.41
82 AKAP8L | I9 | (DLBCL) | (FL)-2.21-1.08-4.98N/A95.57
83 DHFRL1 | I1 | (DLBCL) | (FL)2.211.064.93N/A96.21
84 ANKZF1 | I11 | (DLBCL) | (FL)-2.24-1.05-4.93N/A97.20
85 CENPT | I8 | (DLBCL) | (FL)-1.55-1.67-4.89N/A75.51
86 RP11-488L18.4 | I1 | (DLBCL) | (FL)-1.41-1.83-4.87N/A72.42
87 ARGLU1 | I3 | (DLBCL) | (FL)-1.59-1.62-4.85N/A76.68
88 ACADVL | I9 | (DLBCL) | (FL)-2.671.31-4.85-1.4185.42
89 KCNN4 | I6 | (DLBCL) | (FL)-2.411.10-4.82-1.1394.25
90 ARF1GAP | I9 | (DLBCL) | (FL)-2.15-1.08-4.82N/A95.22
91 C17orf56 | I1 | (DLBCL) | (FL)-1.46-1.74-4.78N/A73.78
92 ACIN1 | I11 | (DLBCL) | (FL)-1.75-1.42-4.76N/A81.72
93 IKBKB | I15 | (DLBCL) | (FL)-2.13-1.08-4.76N/A95.09
94 MSI2 | I14 | (DLBCL) | (FL)-1.54-1.61-4.68N/A76.37
95 AC010422.7 | I3 | (DLBCL) | (FL)-2.601.30-4.68-1.4185.45
96 TTC14 | I10 | (DLBCL) | (FL)-1.19-2.05-4.68N/A68.28
97 AL032819.32 | I4 | (DLBCL) | (FL)2.49-1.204.67-1.2789.29
98 TMC6 | I2 | (DLBCL) | (FL)-2.09-1.09-4.63N/A94.69
99 CARD8 | I4 | (DLBCL) | (FL)-1.89-1.24-4.62N/A87.53
100 TM7SF2 | I2 | (DLBCL) | (FL)1.561.574.61N/A77.30
101 GBA2 | I12 | (DLBCL) | (FL)-1.93-1.20-4.59N/A89.28
102 C11orf83 | I1 | (DLBCL) | (FL)2.181.014.59N/A99.19
103 VPS52 | I14 | (DLBCL) | (FL)-2.08-1.08-4.56N/A95.38
104 SLC39A13 | I6 | (DLBCL) | (FL)-2.451.20-4.55-1.2889.16
105 SFRS7 | I3 | (DLBCL) | (FL)-2.461.22-4.54-1.3088.59
106 C5orf45 | I7 | (DLBCL) | (FL)-2.761.49-4.53-1.7279.01
107 ZNF276 | I7 | (DLBCL) | (FL)2.52-1.274.49-1.3886.17
108 SFRS7 | I4 | (DLBCL) | (FL)-2.421.22-4.40-1.3088.38
109 CLK2 | I4 | (DLBCL) | (FL)-2.00-1.09-4.37N/A94.27
110 CDC42SE1 C1orf56 | Ix | (DLBCL) | (FL)-1.96-1.12-4.36N/A92.65
111 RBM5 | I7 | (DLBCL) | (FL)-1.54-1.47-4.28N/A79.00
112 LRCH4 | I17 | (DLBCL) | (FL)-2.101.02-4.20-1.0398.44
113 GALT | I4 | (DLBCL) | (FL)-2.331.21-4.18-1.3088.34
114 CBLN3 | I1 | (DLBCL) | (FL)-1.11-1.93-4.17N/A68.43
115 SLC29A2 | I9 | (DLBCL) | (FL)1.701.284.16N/A85.11
116 AC010422.7 | I5 | (DLBCL) | (FL)-2.431.30-4.15-1.4584.41
117 TTC14 | I11 | (DLBCL) | (FL)-1.01-2.05-4.13N/A66.42
118 APLNR | I1 | (DLBCL) | (FL)1.221.703.95N/A72.26
119 VAMP2 AC129492.6 | Ix | (DLBCL) | (FL)-2.581.55-3.86-1.9675.52
120 PARP8 | I1 | (DLBCL) | (FL)1.821.093.84N/A94.12
121 CHD3 | I38 | (DLBCL) | (FL)-1.16-1.71-3.83N/A71.36
122 UBXN11 | I12 | (DLBCL) | (FL)-1.14-1.71-3.78N/A71.15
123 TCEA2 | I2 | (DLBCL) | (FL)1.311.523.78N/A76.00
124 TMEM18 | I2 | (DLBCL) | (FL)1.231.613.77N/A73.69
125 CENPL | I1 | (DLBCL) | (FL)1.591.243.73N/A86.01
126 SFRS1 | I3 | (DLBCL) | (FL)-1.991.08-3.69-1.1294.73
127 SFRS6 | I3 | (DLBCL) | (FL)-1.951.05-3.68-1.0796.69
128 ATG9B NOS3 | Ix | (DLBCL) | (FL)2.07-1.153.66-1.2490.20
129 PRRT3 CRELD1 | Ix | (DLBCL) | (FL)1.631.183.65N/A88.59
130 WDR42A | I12 | (DLBCL) | (FL)-1.941.06-3.61-1.1095.47
131 C1orf63 | I3 | (DLBCL) | (FL)-1.16-1.59-3.57N/A73.14
132 TBC1D10C | I1 | (DLBCL) | (FL)1.321.433.56N/A77.99
133 CLK2 | I3 | (DLBCL) | (FL)-1.70-1.09-3.56N/A93.40
134 NFATC2IP | I3 | (DLBCL) | (FL)-1.74-1.06-3.55N/A95.42
135 ANKRD10 | I5 | (DLBCL) | (FL)-1.58-1.18-3.54N/A88.27
136 RNF6 | I1 | (DLBCL) | (FL)1.91-1.073.51-1.1294.75
137 HAAO | I8 | (DLBCL) | (FL)1.621.143.49N/A90.61
138 RPL9 | I1 | (DLBCL) | (FL)-2.2216.153.46N/A30.86
139 CYR61 | I3 | (DLBCL) | (FL)-1.04-1.68-3.44N/A70.53
140 ZNF688 | I4 | (DLBCL) | (FL)1.381.263.30N/A83.61
141 SLC6A16 | I6 | (DLBCL) | (FL)-1.39-1.26-3.29N/A83.85
142 TFIP11 | I14 | (DLBCL) | (FL)1.521.103.16N/A92.08
143 MBD4 | I7 | (DLBCL) | (FL)-1.61-1.03-3.16N/A97.40
144 SFRS7 | I5 | (DLBCL) | (FL)-1.921.22-3.12-1.4185.39
145 C11orf48 | I5 | (DLBCL) | (FL)1.391.193.11N/A86.66
146 HNRNPH1 | I4 | (DLBCL) | (FL)-1.39-1.18-3.08N/A87.21
147 ATP8B1 | I17 | (DLBCL) | (FL)2.14-1.443.06-1.9675.57
148 SLC25A28 | I2 | (DLBCL) | (FL)-1.861.19-3.05-1.3886.36
149 POLD2 | I3 | (DLBCL) | (FL)1.291.202.94N/A85.66
150 CUL9 | I34 | (DLBCL) | (FL)2.41-1.822.91-3.5664.05
151 CLK1 | I5 | (DLBCL) | (FL)-1.10-1.35-2.88N/A77.97
152 AGAP2 | I17 | (DLBCL) | (FL)1.62-1.102.80-1.1991.84
153 C20orf198 | I1 | (DLBCL) | (FL)1.001.382.76N/A76.04
154 RP4-644F6.3 | I3 | (DLBCL) | (FL)1.031.342.73N/A77.43
155 FOS | I3 | (DLBCL) | (FL)1.61-1.152.67-1.3287.89
156 PAXIP1 | I20 | (DLBCL) | (FL)1.45-1.022.67-1.0497.89
157 ANKH | I10 | (DLBCL) | (FL)-1.411.00-2.65-1.0199.65
158 ZNF688 | I5 | (DLBCL) | (FL)1.061.262.64N/A80.59
159 AC005071.2 PMS2L8 | Ix | (DLBCL) | (FL)1.201.152.63N/A87.70
160 CHST11 | I1 | (DLBCL) | (FL)1.56-1.132.60-1.3088.55
161 PSMB7 | I9 | (DLBCL) | (FL)-1.611.19-2.56-1.4684.35
162 MYO19 | I25 | (DLBCL) | (FL)1.72-1.362.43-2.0674.27
163 HNRPDL | I7 | (DLBCL) | (FL)-1.441.13-2.41-1.3188.11
164 CARS | I21 | (DLBCL) | (FL)1.25-1.002.37-1.0199.64
165 ANKH | I9 | (DLBCL) | (FL)-1.241.00-2.36-1.0199.61
166 ZNF397 | I3 | (DLBCL) | (FL)1.65-1.332.35-2.0075.00
167 AC084018.28 | I1 | (DLBCL) | (FL)1.53-1.232.35-1.6480.49
168 FNDC8 NLE1 | Ix | (DLBCL) | (FL)1.041.122.31N/A88.13
169 PCSK7 | I16 | (DLBCL) | (FL)1.141.042.29N/A95.55
170 ARTS-1 | I19 | (DLBCL) | (FL)1.051.102.28N/A89.62
171 LDB1 | I10 | (DLBCL) | (FL)-1.071.01-2.09-1.0199.32
172 TMEM41B | I7 | (DLBCL) | (FL)1.72-1.612.04-5.0259.97