Alternative expression values of the type: Intron for comparison: DLBCL_vs_FL (abs(SI) value > 2)


Distribution of log2 SI values for comparison: DLBCL_vs_FL and data type: Intron

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: Intron. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed Intron features

The following table provides a ranked list of alternatively expressed Intron features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKDLBCL_vs_FL (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 TMEM41B | I7 | (DLBCL) | (FL)1.72-1.612.04-5.0259.97
2 CUL9 | I34 | (DLBCL) | (FL)2.41-1.822.91-3.5664.05
3 MYO19 | I25 | (DLBCL) | (FL)1.72-1.362.43-2.0674.27
4 ZNF397 | I3 | (DLBCL) | (FL)1.65-1.332.35-2.0075.00
5 VAMP2 AC129492.6 | Ix | (DLBCL) | (FL)-2.581.55-3.86-1.9675.52
6 ATP8B1 | I17 | (DLBCL) | (FL)2.14-1.443.06-1.9675.57
7 C5orf45 | I7 | (DLBCL) | (FL)-2.761.49-4.53-1.7279.01
8 AC084018.28 | I1 | (DLBCL) | (FL)1.53-1.232.35-1.6480.49
9 PSMB7 | I9 | (DLBCL) | (FL)-1.611.19-2.56-1.4684.35
10 AC010422.7 | I5 | (DLBCL) | (FL)-2.431.30-4.15-1.4584.41
11 SFRS7 | I5 | (DLBCL) | (FL)-1.921.22-3.12-1.4185.39
12 ACADVL | I9 | (DLBCL) | (FL)-2.671.31-4.85-1.4185.42
13 AC010422.7 | I3 | (DLBCL) | (FL)-2.601.30-4.68-1.4185.45
14 ZNF276 | I7 | (DLBCL) | (FL)2.52-1.274.49-1.3886.17
15 SLC25A28 | I2 | (DLBCL) | (FL)-1.861.19-3.05-1.3886.36
16 FOS | I3 | (DLBCL) | (FL)1.61-1.152.67-1.3287.89
17 HNRPDL | I7 | (DLBCL) | (FL)-1.441.13-2.41-1.3188.11
18 GALT | I4 | (DLBCL) | (FL)-2.331.21-4.18-1.3088.34
19 SFRS7 | I4 | (DLBCL) | (FL)-2.421.22-4.40-1.3088.38
20 CHST11 | I1 | (DLBCL) | (FL)1.56-1.132.60-1.3088.55
21 SFRS7 | I3 | (DLBCL) | (FL)-2.461.22-4.54-1.3088.59
22 SLC39A13 | I6 | (DLBCL) | (FL)-2.451.20-4.55-1.2889.16
23 AL032819.32 | I4 | (DLBCL) | (FL)2.49-1.204.67-1.2789.29
24 ATG9B NOS3 | Ix | (DLBCL) | (FL)2.07-1.153.66-1.2490.20
25 WDR45 | I7 | (DLBCL) | (FL)-2.861.19-6.09-1.2291.05
26 C17orf62 | I2 | (DLBCL) | (FL)-3.491.23-9.15-1.2191.46
27 AGAP2 | I17 | (DLBCL) | (FL)1.62-1.102.80-1.1991.84
28 ACADVL | I10 | (DLBCL) | (FL)-4.961.31-23.77-1.1992.16
29 SFRS5 | I5 | (DLBCL) | (FL)-3.151.18-7.53-1.1892.49
30 COQ4 | I5 | (DLBCL) | (FL)-2.851.13-6.40-1.1493.89
31 METT11D1 | I9 | (DLBCL) | (FL)-3.041.13-7.27-1.1394.21
32 KCNN4 | I6 | (DLBCL) | (FL)-2.411.10-4.82-1.1394.25
33 SYTL1 | I10 | (DLBCL) | (FL)-2.611.10-5.52-1.1294.52
34 SFRS1 | I3 | (DLBCL) | (FL)-1.991.08-3.69-1.1294.73
35 RNF6 | I1 | (DLBCL) | (FL)1.91-1.073.51-1.1294.75
36 AGAP2 | I18 | (DLBCL) | (FL)2.60-1.105.53-1.1194.92
37 C16orf58 | I9 | (DLBCL) | (FL)-3.251.11-8.53-1.1195.19
38 SH3GLB2 | I8 | (DLBCL) | (FL)-2.791.09-6.31-1.1095.34
39 WDR42A | I12 | (DLBCL) | (FL)-1.941.06-3.61-1.1095.47
40 CCS | I3 | (DLBCL) | (FL)-2.661.07-5.89-1.0896.29
41 SFRS6 | I3 | (DLBCL) | (FL)-1.951.05-3.68-1.0796.69
42 ZNF266 | I7 | (DLBCL) | (FL)-2.921.06-7.13-1.0697.00
43 ZNF266 | I6 | (DLBCL) | (FL)-3.261.06-9.02-1.0697.32
44 PAXIP1 | I20 | (DLBCL) | (FL)1.45-1.022.67-1.0497.89
45 LRCH4 | I17 | (DLBCL) | (FL)-2.101.02-4.20-1.0398.44
46 LDB1 | I10 | (DLBCL) | (FL)-1.071.01-2.09-1.0199.32
47 CDK10 | I8 | (DLBCL) | (FL)-3.051.01-8.23-1.0199.60
48 CDK10 | I9 | (DLBCL) | (FL)-3.051.01-8.24-1.0199.60
49 ANKH | I9 | (DLBCL) | (FL)-1.241.00-2.36-1.0199.61
50 CARS | I21 | (DLBCL) | (FL)1.25-1.002.37-1.0199.64
51 ANKH | I10 | (DLBCL) | (FL)-1.411.00-2.65-1.0199.65
52 PTPN1L | I3 | (DLBCL) | (FL)2.66-1.006.31-1.0099.92
53 HNRNPH1 | I4 | (DLBCL) | (FL)-1.39-1.18-3.08N/A87.21
54 PARP8 | I1 | (DLBCL) | (FL)1.821.093.84N/A94.12
55 CDC42SE1 C1orf56 | Ix | (DLBCL) | (FL)-1.96-1.12-4.36N/A92.65
56 TCIRG1 | I5 | (DLBCL) | (FL)-2.82-1.24-8.77N/A90.90
57 FNBP4 | I11 | (DLBCL) | (FL)-1.57-1.74-5.16N/A74.77
58 FCRL2 | I5 | (DLBCL) | (FL)-2.17-2.08-9.34N/A75.31
59 CXXC1 | I11 | (DLBCL) | (FL)-2.81-1.15-8.11N/A93.57
60 IL17RB | I8 | (DLBCL) | (FL)-1.29-2.84-6.96N/A65.00
61 ATHL1 | I6 | (DLBCL) | (FL)-1.42-2.45-6.57N/A67.76
62 CENPT | I8 | (DLBCL) | (FL)-1.55-1.67-4.89N/A75.51
63 IFFO1 | I8 | (DLBCL) | (FL)-2.64-1.24-7.74N/A90.54
64 SLC6A16 | I2 | (DLBCL) | (FL)-1.99-1.26-5.00N/A87.52
65 RP4-644F6.3 | I3 | (DLBCL) | (FL)1.031.342.73N/A77.43
66 CENPL | I1 | (DLBCL) | (FL)1.591.243.73N/A86.01
67 BTNL9 | I11 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.05
68 C17orf56 | I10 | (DLBCL) | (FL)-1.68-1.74-5.60N/A75.59
69 BAT1 | I9 | (DLBCL) | (FL)-2.37-1.07-5.53N/A96.24
70 RNF167 | I2 | (DLBCL) | (FL)1.772.016.88N/A73.37
71 CLK2 | I4 | (DLBCL) | (FL)-2.00-1.09-4.37N/A94.27
72 NFATC2IP | I3 | (DLBCL) | (FL)-1.74-1.06-3.55N/A95.42
73 CYR61 | I3 | (DLBCL) | (FL)-1.04-1.68-3.44N/A70.53
74 ANKZF1 | I10 | (DLBCL) | (FL)-3.00-1.05-8.35N/A97.88
75 FCRL2 | I7 | (DLBCL) | (FL)-1.48-2.08-5.82N/A70.63
76 OGT | I4 | (DLBCL) | (FL)-1.49-2.03-5.70N/A71.05
77 TM7SF2 | I2 | (DLBCL) | (FL)1.561.574.61N/A77.30
78 BTNL9 | I8 | (DLBCL) | (FL)-1.69-2.57-8.28N/A69.16
79 DHFRL1 | I1 | (DLBCL) | (FL)2.211.064.93N/A96.21
80 POLD2 | I3 | (DLBCL) | (FL)1.291.202.94N/A85.66
81 C19orf6 | I4 | (DLBCL) | (FL)-2.80-1.45-10.04N/A86.21
82 ARGLU1 | I4 | (DLBCL) | (FL)-1.88-1.62-5.94N/A78.76
83 FADS3 | I8 | (DLBCL) | (FL)-3.81-1.50-20.98N/A88.29
84 TTC14 | I11 | (DLBCL) | (FL)-1.01-2.05-4.13N/A66.42
85 ZNF76 | I9 | (DLBCL) | (FL)-2.10-1.16-4.99N/A91.41
86 CLK1 | I5 | (DLBCL) | (FL)-1.10-1.35-2.88N/A77.97
87 METRN | I3 | (DLBCL) | (FL)2.681.388.85N/A87.10
88 MBD4 | I7 | (DLBCL) | (FL)-1.61-1.03-3.16N/A97.40
89 TBC1D10C | I1 | (DLBCL) | (FL)1.321.433.56N/A77.99
90 CARD8 | I4 | (DLBCL) | (FL)-1.89-1.24-4.62N/A87.53
91 MSI2 | I14 | (DLBCL) | (FL)-1.54-1.61-4.68N/A76.37
92 ZNF688 | I5 | (DLBCL) | (FL)1.061.262.64N/A80.59
93 CDK5RAP3 | I7 | (DLBCL) | (FL)-3.41-1.18-12.48N/A93.94
94 SGSM3 | I19 | (DLBCL) | (FL)-2.70-1.19-7.74N/A92.00
95 AC005071.2 PMS2L8 | Ix | (DLBCL) | (FL)1.201.152.63N/A87.70
96 SLC29A2 | I9 | (DLBCL) | (FL)1.701.284.16N/A85.11
97 ANO9 | I19 | (DLBCL) | (FL)-2.22-1.18-5.51N/A91.02
98 BTNL9 | I13 | (DLBCL) | (FL)-1.86-2.57-9.33N/A70.32
99 CIITA | I22 | (DLBCL) | (FL)-1.91-1.82-6.80N/A76.27
100 RBM6 | I14 | (DLBCL) | (FL)-1.73-1.94-6.44N/A73.75
101 FNDC8 NLE1 | Ix | (DLBCL) | (FL)1.041.122.31N/A88.13
102 UBA7 | I12 | (DLBCL) | (FL)-3.38-1.10-11.52N/A96.14
103 HAAO | I8 | (DLBCL) | (FL)1.621.143.49N/A90.61
104 ANKZF1 | I11 | (DLBCL) | (FL)-2.24-1.05-4.93N/A97.20
105 SFRS14 | I9 | (DLBCL) | (FL)-2.23-1.64-7.66N/A80.53
106 DDX17 | I11 | (DLBCL) | (FL)-3.00-1.31-10.43N/A89.76
107 SLC6A16 | I6 | (DLBCL) | (FL)-1.39-1.26-3.29N/A83.85
108 UBXN11 | I12 | (DLBCL) | (FL)-1.14-1.71-3.78N/A71.15
109 ILF3 | I11 | (DLBCL) | (FL)-2.16-1.25-5.59N/A88.49
110 CAPN10 | I8 | (DLBCL) | (FL)-1.98-1.41-5.54N/A83.40
111 TMC6 | I2 | (DLBCL) | (FL)-2.09-1.09-4.63N/A94.69
112 PCSK7 | I16 | (DLBCL) | (FL)1.141.042.29N/A95.55
113 AP1G2 | I16 | (DLBCL) | (FL)-2.96-1.26-9.84N/A90.69
114 CEP250 | I18 | (DLBCL) | (FL)-1.75-1.67-5.61N/A77.18
115 MAN2C1 | I19 | (DLBCL) | (FL)-2.55-1.15-6.72N/A93.17
116 LENG8 | I16 | (DLBCL) | (FL)-1.03-3.95-8.09N/A60.35
117 PRRT3 CRELD1 | Ix | (DLBCL) | (FL)1.631.183.65N/A88.59
118 BTNL9 | I7 | (DLBCL) | (FL)-1.00-2.57-5.14N/A63.46
119 CBLN3 | I1 | (DLBCL) | (FL)-1.11-1.93-4.17N/A68.43
120 TUBGCP6 | I23 | (DLBCL) | (FL)-1.14-2.78-6.13N/A63.97
121 DDX17 | I12 | (DLBCL) | (FL)-2.90-1.31-9.76N/A89.50
122 CHD3 | I38 | (DLBCL) | (FL)-1.16-1.71-3.83N/A71.36
123 RP11-488L18.4 | I1 | (DLBCL) | (FL)-1.41-1.83-4.87N/A72.42
124 TFIP11 | I14 | (DLBCL) | (FL)1.521.103.16N/A92.08
125 METTL3 | I9 | (DLBCL) | (FL)-2.16-1.76-7.87N/A78.55
126 APBB3 | I8 | (DLBCL) | (FL)-1.86-2.30-8.32N/A71.83
127 TYK2 | I18 | (DLBCL) | (FL)-3.13-1.50-13.13N/A86.35
128 C11orf83 | I1 | (DLBCL) | (FL)2.181.014.59N/A99.19
129 FCRL2 | I6 | (DLBCL) | (FL)-1.73-2.08-6.89N/A72.49
130 RPL9 | I1 | (DLBCL) | (FL)-2.2216.153.46N/A30.86
131 TAF1C | I7 | (DLBCL) | (FL)-1.15-2.38-5.29N/A65.76
132 APLNR | I1 | (DLBCL) | (FL)1.221.703.95N/A72.26
133 ANKRD10 | I5 | (DLBCL) | (FL)-1.58-1.18-3.54N/A88.27
134 PRPF39 | I3 | (DLBCL) | (FL)-1.99-1.34-5.33N/A85.10
135 TTC14 | I10 | (DLBCL) | (FL)-1.19-2.05-4.68N/A68.28
136 SNRNP70 | I8 | (DLBCL) | (FL)-3.39-1.13-11.86N/A95.35
137 ANKZF1 | I9 | (DLBCL) | (FL)-2.76-1.05-7.11N/A97.71
138 RBM5 | I7 | (DLBCL) | (FL)-1.54-1.47-4.28N/A79.00
139 C1orf63 | I3 | (DLBCL) | (FL)-1.16-1.59-3.57N/A73.14
140 EZH1 | I19 | (DLBCL) | (FL)-2.20-1.38-6.35N/A85.14
141 TCEA2 | I2 | (DLBCL) | (FL)1.311.523.78N/A76.00
142 RP4-644F6.3 | I4 | (DLBCL) | (FL)1.971.345.27N/A85.01
143 CLK2 | I3 | (DLBCL) | (FL)-1.70-1.09-3.56N/A93.40
144 NEIL1 | I5 | (DLBCL) | (FL)-1.54-3.27-9.49N/A65.51
145 ACIN1 | I11 | (DLBCL) | (FL)-1.75-1.42-4.76N/A81.72
146 NEIL1 | I5 | (DLBCL) | (FL)-1.01-3.27-6.58N/A61.39
147 AP1G2 | I4 | (DLBCL) | (FL)-3.12-1.26-10.97N/A91.08
148 SFRS14 | I10 | (DLBCL) | (FL)-1.99-1.64-6.49N/A79.16
149 AP1G2 | I15 | (DLBCL) | (FL)-2.22-1.26-5.91N/A88.33
150 C20orf198 | I1 | (DLBCL) | (FL)1.001.382.76N/A76.04
151 ARF1GAP | I9 | (DLBCL) | (FL)-2.15-1.08-4.82N/A95.22
152 ZNF688 | I4 | (DLBCL) | (FL)1.381.263.30N/A83.61
153 NEIL1 | I6 | (DLBCL) | (FL)-1.94-3.27-12.51N/A68.07
154 C11orf48 | I5 | (DLBCL) | (FL)1.391.193.11N/A86.66
155 CYTH1 | I13 | (DLBCL) | (FL)-2.42-1.08-5.78N/A95.92
156 CDK5RAP3 | I5 | (DLBCL) | (FL)-2.96-1.18-9.18N/A93.16
157 AKAP8L | I9 | (DLBCL) | (FL)-2.21-1.08-4.98N/A95.57
158 PH-4 | I6 | (DLBCL) | (FL)-2.80-1.10-7.66N/A95.48
159 PILRB | I6 | (DLBCL) | (FL)-1.41-3.07-8.19N/A65.20
160 ARTS-1 | I19 | (DLBCL) | (FL)1.051.102.28N/A89.62
161 VPS52 | I14 | (DLBCL) | (FL)-2.08-1.08-4.56N/A95.38
162 ELAVL1 | I1 | (DLBCL) | (FL)3.141.2310.81N/A92.04
163 BTNL9 | I10 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.06
164 TMEM18 | I2 | (DLBCL) | (FL)1.231.613.77N/A73.69
165 LENG8 | I15 | (DLBCL) | (FL)-1.87-3.95-14.45N/A66.04
166 SNHG12 | I4 | (DLBCL) | (FL)-1.43-2.14-5.75N/A69.70
167 ARGLU1 | I3 | (DLBCL) | (FL)-1.59-1.62-4.85N/A76.68
168 ZMIZ2 | I8 | (DLBCL) | (FL)-2.58-1.41-8.41N/A86.06
169 DDX5 | I11 | (DLBCL) | (FL)-2.88-1.03-7.58N/A98.57
170 C17orf56 | I1 | (DLBCL) | (FL)-1.46-1.74-4.78N/A73.78
171 IKBKB | I15 | (DLBCL) | (FL)-2.13-1.08-4.76N/A95.09
172 GBA2 | I12 | (DLBCL) | (FL)-1.93-1.20-4.59N/A89.28