Alternative expression values of the type: Intron for comparison: DLBCL_vs_FL (abs(SI) value > 2)


Distribution of log2 SI values for comparison: DLBCL_vs_FL and data type: Intron

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: Intron. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed Intron features

The following table provides a ranked list of alternatively expressed Intron features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKDLBCL_vs_FL (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 RPL9 | I1 | (DLBCL) | (FL)-2.2216.153.46N/A30.86
2 LENG8 | I16 | (DLBCL) | (FL)-1.03-3.95-8.09N/A60.35
3 LENG8 | I15 | (DLBCL) | (FL)-1.87-3.95-14.45N/A66.04
4 NEIL1 | I5 | (DLBCL) | (FL)-1.54-3.27-9.49N/A65.51
5 NEIL1 | I5 | (DLBCL) | (FL)-1.01-3.27-6.58N/A61.39
6 NEIL1 | I6 | (DLBCL) | (FL)-1.94-3.27-12.51N/A68.07
7 PILRB | I6 | (DLBCL) | (FL)-1.41-3.07-8.19N/A65.20
8 IL17RB | I8 | (DLBCL) | (FL)-1.29-2.84-6.96N/A65.00
9 TUBGCP6 | I23 | (DLBCL) | (FL)-1.14-2.78-6.13N/A63.97
10 BTNL9 | I11 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.05
11 BTNL9 | I8 | (DLBCL) | (FL)-1.69-2.57-8.28N/A69.16
12 BTNL9 | I13 | (DLBCL) | (FL)-1.86-2.57-9.33N/A70.32
13 BTNL9 | I7 | (DLBCL) | (FL)-1.00-2.57-5.14N/A63.46
14 BTNL9 | I10 | (DLBCL) | (FL)-2.15-2.57-11.37N/A72.06
15 ATHL1 | I6 | (DLBCL) | (FL)-1.42-2.45-6.57N/A67.76
16 TAF1C | I7 | (DLBCL) | (FL)-1.15-2.38-5.29N/A65.76
17 APBB3 | I8 | (DLBCL) | (FL)-1.86-2.30-8.32N/A71.83
18 SNHG12 | I4 | (DLBCL) | (FL)-1.43-2.14-5.75N/A69.70
19 FCRL2 | I5 | (DLBCL) | (FL)-2.17-2.08-9.34N/A75.31
20 FCRL2 | I7 | (DLBCL) | (FL)-1.48-2.08-5.82N/A70.63
21 FCRL2 | I6 | (DLBCL) | (FL)-1.73-2.08-6.89N/A72.49
22 TTC14 | I11 | (DLBCL) | (FL)-1.01-2.05-4.13N/A66.42
23 TTC14 | I10 | (DLBCL) | (FL)-1.19-2.05-4.68N/A68.28
24 OGT | I4 | (DLBCL) | (FL)-1.49-2.03-5.70N/A71.05
25 RNF167 | I2 | (DLBCL) | (FL)1.772.016.88N/A73.37
26 RBM6 | I14 | (DLBCL) | (FL)-1.73-1.94-6.44N/A73.75
27 CBLN3 | I1 | (DLBCL) | (FL)-1.11-1.93-4.17N/A68.43
28 RP11-488L18.4 | I1 | (DLBCL) | (FL)-1.41-1.83-4.87N/A72.42
29 CUL9 | I34 | (DLBCL) | (FL)2.41-1.822.91-3.5664.05
30 CIITA | I22 | (DLBCL) | (FL)-1.91-1.82-6.80N/A76.27
31 METTL3 | I9 | (DLBCL) | (FL)-2.16-1.76-7.87N/A78.55
32 C17orf56 | I10 | (DLBCL) | (FL)-1.68-1.74-5.60N/A75.59
33 C17orf56 | I1 | (DLBCL) | (FL)-1.46-1.74-4.78N/A73.78
34 FNBP4 | I11 | (DLBCL) | (FL)-1.57-1.74-5.16N/A74.77
35 UBXN11 | I12 | (DLBCL) | (FL)-1.14-1.71-3.78N/A71.15
36 CHD3 | I38 | (DLBCL) | (FL)-1.16-1.71-3.83N/A71.36
37 APLNR | I1 | (DLBCL) | (FL)1.221.703.95N/A72.26
38 CYR61 | I3 | (DLBCL) | (FL)-1.04-1.68-3.44N/A70.53
39 CENPT | I8 | (DLBCL) | (FL)-1.55-1.67-4.89N/A75.51
40 CEP250 | I18 | (DLBCL) | (FL)-1.75-1.67-5.61N/A77.18
41 SFRS14 | I9 | (DLBCL) | (FL)-2.23-1.64-7.66N/A80.53
42 SFRS14 | I10 | (DLBCL) | (FL)-1.99-1.64-6.49N/A79.16
43 ARGLU1 | I4 | (DLBCL) | (FL)-1.88-1.62-5.94N/A78.76
44 ARGLU1 | I3 | (DLBCL) | (FL)-1.59-1.62-4.85N/A76.68
45 MSI2 | I14 | (DLBCL) | (FL)-1.54-1.61-4.68N/A76.37
46 TMEM41B | I7 | (DLBCL) | (FL)1.72-1.612.04-5.0259.97
47 TMEM18 | I2 | (DLBCL) | (FL)1.231.613.77N/A73.69
48 C1orf63 | I3 | (DLBCL) | (FL)-1.16-1.59-3.57N/A73.14
49 TM7SF2 | I2 | (DLBCL) | (FL)1.561.574.61N/A77.30
50 VAMP2 AC129492.6 | Ix | (DLBCL) | (FL)-2.581.55-3.86-1.9675.52
51 TCEA2 | I2 | (DLBCL) | (FL)1.311.523.78N/A76.00
52 TYK2 | I18 | (DLBCL) | (FL)-3.13-1.50-13.13N/A86.35
53 FADS3 | I8 | (DLBCL) | (FL)-3.81-1.50-20.98N/A88.29
54 C5orf45 | I7 | (DLBCL) | (FL)-2.761.49-4.53-1.7279.01
55 RBM5 | I7 | (DLBCL) | (FL)-1.54-1.47-4.28N/A79.00
56 C19orf6 | I4 | (DLBCL) | (FL)-2.80-1.45-10.04N/A86.21
57 ATP8B1 | I17 | (DLBCL) | (FL)2.14-1.443.06-1.9675.57
58 TBC1D10C | I1 | (DLBCL) | (FL)1.321.433.56N/A77.99
59 ACIN1 | I11 | (DLBCL) | (FL)-1.75-1.42-4.76N/A81.72
60 ZMIZ2 | I8 | (DLBCL) | (FL)-2.58-1.41-8.41N/A86.06
61 CAPN10 | I8 | (DLBCL) | (FL)-1.98-1.41-5.54N/A83.40
62 METRN | I3 | (DLBCL) | (FL)2.681.388.85N/A87.10
63 EZH1 | I19 | (DLBCL) | (FL)-2.20-1.38-6.35N/A85.14
64 C20orf198 | I1 | (DLBCL) | (FL)1.001.382.76N/A76.04
65 MYO19 | I25 | (DLBCL) | (FL)1.72-1.362.43-2.0674.27
66 CLK1 | I5 | (DLBCL) | (FL)-1.10-1.35-2.88N/A77.97
67 RP4-644F6.3 | I3 | (DLBCL) | (FL)1.031.342.73N/A77.43
68 RP4-644F6.3 | I4 | (DLBCL) | (FL)1.971.345.27N/A85.01
69 PRPF39 | I3 | (DLBCL) | (FL)-1.99-1.34-5.33N/A85.10
70 ZNF397 | I3 | (DLBCL) | (FL)1.65-1.332.35-2.0075.00
71 ACADVL | I9 | (DLBCL) | (FL)-2.671.31-4.85-1.4185.42
72 ACADVL | I10 | (DLBCL) | (FL)-4.961.31-23.77-1.1992.16
73 DDX17 | I11 | (DLBCL) | (FL)-3.00-1.31-10.43N/A89.76
74 DDX17 | I12 | (DLBCL) | (FL)-2.90-1.31-9.76N/A89.50
75 AC010422.7 | I3 | (DLBCL) | (FL)-2.601.30-4.68-1.4185.45
76 AC010422.7 | I5 | (DLBCL) | (FL)-2.431.30-4.15-1.4584.41
77 SLC29A2 | I9 | (DLBCL) | (FL)1.701.284.16N/A85.11
78 ZNF276 | I7 | (DLBCL) | (FL)2.52-1.274.49-1.3886.17
79 AP1G2 | I16 | (DLBCL) | (FL)-2.96-1.26-9.84N/A90.69
80 AP1G2 | I4 | (DLBCL) | (FL)-3.12-1.26-10.97N/A91.08
81 AP1G2 | I15 | (DLBCL) | (FL)-2.22-1.26-5.91N/A88.33
82 ZNF688 | I5 | (DLBCL) | (FL)1.061.262.64N/A80.59
83 ZNF688 | I4 | (DLBCL) | (FL)1.381.263.30N/A83.61
84 SLC6A16 | I2 | (DLBCL) | (FL)-1.99-1.26-5.00N/A87.52
85 SLC6A16 | I6 | (DLBCL) | (FL)-1.39-1.26-3.29N/A83.85
86 ILF3 | I11 | (DLBCL) | (FL)-2.16-1.25-5.59N/A88.49
87 CARD8 | I4 | (DLBCL) | (FL)-1.89-1.24-4.62N/A87.53
88 TCIRG1 | I5 | (DLBCL) | (FL)-2.82-1.24-8.77N/A90.90
89 CENPL | I1 | (DLBCL) | (FL)1.591.243.73N/A86.01
90 IFFO1 | I8 | (DLBCL) | (FL)-2.64-1.24-7.74N/A90.54
91 AC084018.28 | I1 | (DLBCL) | (FL)1.53-1.232.35-1.6480.49
92 C17orf62 | I2 | (DLBCL) | (FL)-3.491.23-9.15-1.2191.46
93 ELAVL1 | I1 | (DLBCL) | (FL)3.141.2310.81N/A92.04
94 SFRS7 | I3 | (DLBCL) | (FL)-2.461.22-4.54-1.3088.59
95 SFRS7 | I4 | (DLBCL) | (FL)-2.421.22-4.40-1.3088.38
96 SFRS7 | I5 | (DLBCL) | (FL)-1.921.22-3.12-1.4185.39
97 GALT | I4 | (DLBCL) | (FL)-2.331.21-4.18-1.3088.34
98 AL032819.32 | I4 | (DLBCL) | (FL)2.49-1.204.67-1.2789.29
99 SLC39A13 | I6 | (DLBCL) | (FL)-2.451.20-4.55-1.2889.16
100 GBA2 | I12 | (DLBCL) | (FL)-1.93-1.20-4.59N/A89.28
101 POLD2 | I3 | (DLBCL) | (FL)1.291.202.94N/A85.66
102 SGSM3 | I19 | (DLBCL) | (FL)-2.70-1.19-7.74N/A92.00
103 WDR45 | I7 | (DLBCL) | (FL)-2.861.19-6.09-1.2291.05
104 SLC25A28 | I2 | (DLBCL) | (FL)-1.861.19-3.05-1.3886.36
105 C11orf48 | I5 | (DLBCL) | (FL)1.391.193.11N/A86.66
106 PSMB7 | I9 | (DLBCL) | (FL)-1.611.19-2.56-1.4684.35
107 ANO9 | I19 | (DLBCL) | (FL)-2.22-1.18-5.51N/A91.02
108 ANKRD10 | I5 | (DLBCL) | (FL)-1.58-1.18-3.54N/A88.27
109 PRRT3 CRELD1 | Ix | (DLBCL) | (FL)1.631.183.65N/A88.59
110 HNRNPH1 | I4 | (DLBCL) | (FL)-1.39-1.18-3.08N/A87.21
111 SFRS5 | I5 | (DLBCL) | (FL)-3.151.18-7.53-1.1892.49
112 CDK5RAP3 | I7 | (DLBCL) | (FL)-3.41-1.18-12.48N/A93.94
113 CDK5RAP3 | I5 | (DLBCL) | (FL)-2.96-1.18-9.18N/A93.16
114 ZNF76 | I9 | (DLBCL) | (FL)-2.10-1.16-4.99N/A91.41
115 CXXC1 | I11 | (DLBCL) | (FL)-2.81-1.15-8.11N/A93.57
116 ATG9B NOS3 | Ix | (DLBCL) | (FL)2.07-1.153.66-1.2490.20
117 MAN2C1 | I19 | (DLBCL) | (FL)-2.55-1.15-6.72N/A93.17
118 AC005071.2 PMS2L8 | Ix | (DLBCL) | (FL)1.201.152.63N/A87.70
119 FOS | I3 | (DLBCL) | (FL)1.61-1.152.67-1.3287.89
120 HAAO | I8 | (DLBCL) | (FL)1.621.143.49N/A90.61
121 CHST11 | I1 | (DLBCL) | (FL)1.56-1.132.60-1.3088.55
122 METT11D1 | I9 | (DLBCL) | (FL)-3.041.13-7.27-1.1394.21
123 COQ4 | I5 | (DLBCL) | (FL)-2.851.13-6.40-1.1493.89
124 SNRNP70 | I8 | (DLBCL) | (FL)-3.39-1.13-11.86N/A95.35
125 HNRPDL | I7 | (DLBCL) | (FL)-1.441.13-2.41-1.3188.11
126 CDC42SE1 C1orf56 | Ix | (DLBCL) | (FL)-1.96-1.12-4.36N/A92.65
127 FNDC8 NLE1 | Ix | (DLBCL) | (FL)1.041.122.31N/A88.13
128 C16orf58 | I9 | (DLBCL) | (FL)-3.251.11-8.53-1.1195.19
129 SYTL1 | I10 | (DLBCL) | (FL)-2.611.10-5.52-1.1294.52
130 TFIP11 | I14 | (DLBCL) | (FL)1.521.103.16N/A92.08
131 UBA7 | I12 | (DLBCL) | (FL)-3.38-1.10-11.52N/A96.14
132 PH-4 | I6 | (DLBCL) | (FL)-2.80-1.10-7.66N/A95.48
133 KCNN4 | I6 | (DLBCL) | (FL)-2.411.10-4.82-1.1394.25
134 ARTS-1 | I19 | (DLBCL) | (FL)1.051.102.28N/A89.62
135 AGAP2 | I17 | (DLBCL) | (FL)1.62-1.102.80-1.1991.84
136 AGAP2 | I18 | (DLBCL) | (FL)2.60-1.105.53-1.1194.92
137 SH3GLB2 | I8 | (DLBCL) | (FL)-2.791.09-6.31-1.1095.34
138 CLK2 | I4 | (DLBCL) | (FL)-2.00-1.09-4.37N/A94.27
139 CLK2 | I3 | (DLBCL) | (FL)-1.70-1.09-3.56N/A93.40
140 TMC6 | I2 | (DLBCL) | (FL)-2.09-1.09-4.63N/A94.69
141 PARP8 | I1 | (DLBCL) | (FL)1.821.093.84N/A94.12
142 IKBKB | I15 | (DLBCL) | (FL)-2.13-1.08-4.76N/A95.09
143 ARF1GAP | I9 | (DLBCL) | (FL)-2.15-1.08-4.82N/A95.22
144 CYTH1 | I13 | (DLBCL) | (FL)-2.42-1.08-5.78N/A95.92
145 AKAP8L | I9 | (DLBCL) | (FL)-2.21-1.08-4.98N/A95.57
146 VPS52 | I14 | (DLBCL) | (FL)-2.08-1.08-4.56N/A95.38
147 SFRS1 | I3 | (DLBCL) | (FL)-1.991.08-3.69-1.1294.73
148 RNF6 | I1 | (DLBCL) | (FL)1.91-1.073.51-1.1294.75
149 CCS | I3 | (DLBCL) | (FL)-2.661.07-5.89-1.0896.29
150 BAT1 | I9 | (DLBCL) | (FL)-2.37-1.07-5.53N/A96.24
151 DHFRL1 | I1 | (DLBCL) | (FL)2.211.064.93N/A96.21
152 WDR42A | I12 | (DLBCL) | (FL)-1.941.06-3.61-1.1095.47
153 NFATC2IP | I3 | (DLBCL) | (FL)-1.74-1.06-3.55N/A95.42
154 ZNF266 | I6 | (DLBCL) | (FL)-3.261.06-9.02-1.0697.32
155 ZNF266 | I7 | (DLBCL) | (FL)-2.921.06-7.13-1.0697.00
156 ANKZF1 | I10 | (DLBCL) | (FL)-3.00-1.05-8.35N/A97.88
157 ANKZF1 | I11 | (DLBCL) | (FL)-2.24-1.05-4.93N/A97.20
158 ANKZF1 | I9 | (DLBCL) | (FL)-2.76-1.05-7.11N/A97.71
159 SFRS6 | I3 | (DLBCL) | (FL)-1.951.05-3.68-1.0796.69
160 PCSK7 | I16 | (DLBCL) | (FL)1.141.042.29N/A95.55
161 MBD4 | I7 | (DLBCL) | (FL)-1.61-1.03-3.16N/A97.40
162 DDX5 | I11 | (DLBCL) | (FL)-2.88-1.03-7.58N/A98.57
163 LRCH4 | I17 | (DLBCL) | (FL)-2.101.02-4.20-1.0398.44
164 PAXIP1 | I20 | (DLBCL) | (FL)1.45-1.022.67-1.0497.89
165 C11orf83 | I1 | (DLBCL) | (FL)2.181.014.59N/A99.19
166 CDK10 | I8 | (DLBCL) | (FL)-3.051.01-8.23-1.0199.60
167 CDK10 | I9 | (DLBCL) | (FL)-3.051.01-8.24-1.0199.60
168 LDB1 | I10 | (DLBCL) | (FL)-1.071.01-2.09-1.0199.32
169 ANKH | I9 | (DLBCL) | (FL)-1.241.00-2.36-1.0199.61
170 ANKH | I10 | (DLBCL) | (FL)-1.411.00-2.65-1.0199.65
171 CARS | I21 | (DLBCL) | (FL)1.25-1.002.37-1.0199.64
172 PTPN1L | I3 | (DLBCL) | (FL)2.66-1.006.31-1.0099.92