Alternative expression values of the type: NovelJunction for comparison: NeuroMycAmp_vs_NeuroMycNon (abs(SI) value > 2)


Distribution of log2 SI values for comparison: NeuroMycAmp_vs_NeuroMycNon and data type: NovelJunction

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelJunction. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelJunction features

The following table provides a ranked list of alternatively expressed NovelJunction features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKNeuroMycAmp_vs_NeuroMycNon (Gene | Feature | Links)SIGene FCSeq FCReciprocity
(RI)
Percent Seq DE
(PFC)
q-value
1 KCNQ2 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon4.03-1.3811.84-1.3088.470.809
2 MYO19 | E25a_E27a (S1) | NeuroMycAmp | NeuroMycNon2.98-1.047.58-1.0497.950.809
3 PIGF | E1a_E1g (S0) | NeuroMycAmp | NeuroMycNon2.93-1.067.17-1.0697.090.156
4 AC022210.1 | E1a_E2c (S1) | NeuroMycAmp | NeuroMycNon2.761.167.84N/A93.380.809
5 TARBP1 | E18a_E20a (S1) | NeuroMycAmp | NeuroMycNon-2.551.12-5.22-1.1593.450.0678
6 RAC1 | E7a_E9a (S2) | NeuroMycAmp | NeuroMycNon2.54-1.035.63-1.0498.300.809
7 STX8 | E5a_E7a (S1) | NeuroMycAmp | NeuroMycNon-2.511.26-4.53-1.3686.860.809
8 PREPL | E15a_E17a (S2) | NeuroMycAmp | NeuroMycNon2.44-1.274.29-1.3985.970.809
9 MTMR15 | E3a_E5a (S2) | NeuroMycAmp | NeuroMycNon-2.431.40-3.84-1.6779.850.809
10 MKKS | E3a_E5a (S2) | NeuroMycAmp | NeuroMycNon-2.33-1.06-5.35N/A96.480.809
11 ZNF638 | E32b_E36b (S13) | NeuroMycAmp | NeuroMycNon2.321.185.89N/A91.330.809
12 NOP58 | E2a_E5a (S3) | NeuroMycAmp | NeuroMycNon-2.282.04-2.38-10.2054.900.809
13 RP1-34B21.1 | E3a_E5a (S1) | NeuroMycAmp | NeuroMycNon-2.141.51-2.92-2.2572.230.809
14 MMS19 | E7a_E8a (S2) | NeuroMycAmp | NeuroMycNon2.041.094.47N/A94.780.809
15 CSDE1 | E11a_E13a (S1) | NeuroMycAmp | NeuroMycNon-2.001.30-3.08-1.6181.110.809
16 WDR27 | E25a_E27a (S1) | NeuroMycAmp | NeuroMycNon1.921.003.79N/A99.880.809
17 YJEFN3 | E4a_E8a (S5) | NeuroMycAmp | NeuroMycNon-1.88-1.10-4.07N/A93.360.809
18 TMEM131 | E30a_E32a (S1) | NeuroMycAmp | NeuroMycNon1.86-1.063.43-1.1095.390.809
19 MED24 | E24a_E26a (S1) | NeuroMycAmp | NeuroMycNon1.82-1.103.21-1.1892.490.458
20 CCDC150 | E24a_E25b (S0) | NeuroMycAmp | NeuroMycNon1.781.093.74N/A94.120.0678
21 CENPE | E24a_E26a (S1) | NeuroMycAmp | NeuroMycNon1.75-1.083.13-1.1493.830.809
22 MANBAL | E1a_E2c (S0) | NeuroMycAmp | NeuroMycNon1.741.193.97N/A88.830.809
23 NME1-NME2 | E1a_E6a (S6) | NeuroMycAmp | NeuroMycNon1.731.906.29N/A74.170.809
24 CDC16 | E14a_E16a (S1) | NeuroMycAmp | NeuroMycNon1.711.143.71N/A91.130.458
25 TUBGCP6 | E15a_E16c (S1) | NeuroMycAmp | NeuroMycNon1.70-1.092.98-1.1892.390.809
26 PUM1 | E19a_E21a (S1) | NeuroMycAmp | NeuroMycNon-1.64-1.57-4.90N/A77.940.809
27 NLGN2 | E1a_E3a (S1) | NeuroMycAmp | NeuroMycNon-1.63-1.05-3.26N/A95.770.809
28 SLC9A5 | E8a_E10a (S1) | NeuroMycAmp | NeuroMycNon-1.60-1.01-3.06N/A99.280.809
29 HAUS4 | E6a_E8a (S1) | NeuroMycAmp | NeuroMycNon1.561.323.90N/A83.020.809
30 AARSD1 | E13b_E15a (S1) | NeuroMycAmp | NeuroMycNon1.561.313.84N/A83.430.809
31 ZCCHC7 | E3a_E10a (S6) | NeuroMycAmp | NeuroMycNon1.521.494.28N/A78.360.619
32 CCDC14 | E8a_E10a (S2) | NeuroMycAmp | NeuroMycNon1.501.022.90N/A98.040.809
33 L3MBTL | E20a_E21b (S3) | NeuroMycAmp | NeuroMycNon-1.50-1.24-3.49N/A85.480.809
34 FDPS | E5b_E6a (S5) | NeuroMycAmp | NeuroMycNon1.471.062.95N/A94.820.458
35 RP9P | E5a_E7a (S2) | NeuroMycAmp | NeuroMycNon-1.461.28-2.16-1.9375.870.637
36 MRPL18 | E1b_E3a (S3) | NeuroMycAmp | NeuroMycNon1.441.664.51N/A74.740.809
37 GMIP | E17a_E19a (S1) | NeuroMycAmp | NeuroMycNon-1.42-1.13-3.02N/A90.310.809
38 AC093283.3 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon-1.41-6.98-18.51N/A60.040.809
39 NOL11 | E10a_E12a (S1) | NeuroMycAmp | NeuroMycNon1.39-1.052.50-1.1095.300.809
40 NUP54 | E3a_E10a (S6) | NeuroMycAmp | NeuroMycNon-1.361.12-2.29-1.3188.170.809
41 TMEFF1 | E9a_E11a (S1) | NeuroMycAmp | NeuroMycNon1.32-1.152.16-1.4684.340.809
42 CKB | E5a_E7a (S1) | NeuroMycAmp | NeuroMycNon-1.301.11-2.21-1.3188.130.809
43 ZC3H7A | E18a_E20a (S1) | NeuroMycAmp | NeuroMycNon1.291.042.55N/A95.720.809
44 MPV17 | E8a_E8d (S0) | NeuroMycAmp | NeuroMycNon1.281.283.09N/A82.160.809
45 ARRB1 | E1a_E3a (S1) | NeuroMycAmp | NeuroMycNon-1.27-1.23-2.96N/A84.090.788
46 RPAIN | E4a_E7a (S2) | NeuroMycAmp | NeuroMycNon1.261.012.42N/A98.910.809
47 IARS | E33b_E34b (S1) | NeuroMycAmp | NeuroMycNon1.251.403.32N/A78.210.637
48 C16orf42 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon1.231.122.63N/A89.510.809
49 NCOR2 | E16a_E17a (S0) | NeuroMycAmp | NeuroMycNon-1.22-1.11-2.58N/A90.340.809
50 LRPPRC | E35a_E37a (S3) | NeuroMycAmp | NeuroMycNon1.211.894.37N/A69.890.406
51 ATXN2L | E22c_E22c (S0) | NeuroMycAmp | NeuroMycNon-1.19-1.18-2.71N/A85.590.809
52 CCDC57 | E18a_E19b (S0) | NeuroMycAmp | NeuroMycNon1.17-1.112.04-1.3387.610.809
53 MMS19 | E11c_E13a (S3) | NeuroMycAmp | NeuroMycNon-1.141.09-2.03-1.2689.560.809
54 SEPT3 | E4a_E6a (S2) | NeuroMycAmp | NeuroMycNon-1.12-1.40-3.04N/A76.900.809
55 C11orf30 | E6a_E8a (S2) | NeuroMycAmp | NeuroMycNon-1.111.08-2.00-1.2589.990.809
56 C19orf28 | E6a_E8a (S1) | NeuroMycAmp | NeuroMycNon1.061.142.38N/A86.560.809