Alternative expression values of the type: NovelJunction for comparison: NeuroMycAmp_vs_NeuroMycNon (abs(SI) value > 2)


Distribution of log2 SI values for comparison: NeuroMycAmp_vs_NeuroMycNon and data type: NovelJunction

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelJunction. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelJunction features

The following table provides a ranked list of alternatively expressed NovelJunction features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKNeuroMycAmp_vs_NeuroMycNon (Gene | Feature | Links)SIGene FCSeq FCReciprocity
(RI)
Percent Seq DE
(PFC)
q-value
1 WDR27 | E25a_E27a (S1) | NeuroMycAmp | NeuroMycNon1.921.003.79N/A99.880.809
2 SLC9A5 | E8a_E10a (S1) | NeuroMycAmp | NeuroMycNon-1.60-1.01-3.06N/A99.280.809
3 RPAIN | E4a_E7a (S2) | NeuroMycAmp | NeuroMycNon1.261.012.42N/A98.910.809
4 RAC1 | E7a_E9a (S2) | NeuroMycAmp | NeuroMycNon2.54-1.035.63-1.0498.300.809
5 CCDC14 | E8a_E10a (S2) | NeuroMycAmp | NeuroMycNon1.501.022.90N/A98.040.809
6 MYO19 | E25a_E27a (S1) | NeuroMycAmp | NeuroMycNon2.98-1.047.58-1.0497.950.809
7 PIGF | E1a_E1g (S0) | NeuroMycAmp | NeuroMycNon2.93-1.067.17-1.0697.090.156
8 MKKS | E3a_E5a (S2) | NeuroMycAmp | NeuroMycNon-2.33-1.06-5.35N/A96.480.809
9 NLGN2 | E1a_E3a (S1) | NeuroMycAmp | NeuroMycNon-1.63-1.05-3.26N/A95.770.809
10 ZC3H7A | E18a_E20a (S1) | NeuroMycAmp | NeuroMycNon1.291.042.55N/A95.720.809
11 TMEM131 | E30a_E32a (S1) | NeuroMycAmp | NeuroMycNon1.86-1.063.43-1.1095.390.809
12 NOL11 | E10a_E12a (S1) | NeuroMycAmp | NeuroMycNon1.39-1.052.50-1.1095.300.809
13 FDPS | E5b_E6a (S5) | NeuroMycAmp | NeuroMycNon1.471.062.95N/A94.820.458
14 MMS19 | E7a_E8a (S2) | NeuroMycAmp | NeuroMycNon2.041.094.47N/A94.780.809
15 CCDC150 | E24a_E25b (S0) | NeuroMycAmp | NeuroMycNon1.781.093.74N/A94.120.0678
16 CENPE | E24a_E26a (S1) | NeuroMycAmp | NeuroMycNon1.75-1.083.13-1.1493.830.809
17 TARBP1 | E18a_E20a (S1) | NeuroMycAmp | NeuroMycNon-2.551.12-5.22-1.1593.450.0678
18 AC022210.1 | E1a_E2c (S1) | NeuroMycAmp | NeuroMycNon2.761.167.84N/A93.380.809
19 YJEFN3 | E4a_E8a (S5) | NeuroMycAmp | NeuroMycNon-1.88-1.10-4.07N/A93.360.809
20 MED24 | E24a_E26a (S1) | NeuroMycAmp | NeuroMycNon1.82-1.103.21-1.1892.490.458
21 TUBGCP6 | E15a_E16c (S1) | NeuroMycAmp | NeuroMycNon1.70-1.092.98-1.1892.390.809
22 ZNF638 | E32b_E36b (S13) | NeuroMycAmp | NeuroMycNon2.321.185.89N/A91.330.809
23 CDC16 | E14a_E16a (S1) | NeuroMycAmp | NeuroMycNon1.711.143.71N/A91.130.458
24 NCOR2 | E16a_E17a (S0) | NeuroMycAmp | NeuroMycNon-1.22-1.11-2.58N/A90.340.809
25 GMIP | E17a_E19a (S1) | NeuroMycAmp | NeuroMycNon-1.42-1.13-3.02N/A90.310.809
26 C11orf30 | E6a_E8a (S2) | NeuroMycAmp | NeuroMycNon-1.111.08-2.00-1.2589.990.809
27 MMS19 | E11c_E13a (S3) | NeuroMycAmp | NeuroMycNon-1.141.09-2.03-1.2689.560.809
28 C16orf42 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon1.231.122.63N/A89.510.809
29 MANBAL | E1a_E2c (S0) | NeuroMycAmp | NeuroMycNon1.741.193.97N/A88.830.809
30 KCNQ2 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon4.03-1.3811.84-1.3088.470.809
31 NUP54 | E3a_E10a (S6) | NeuroMycAmp | NeuroMycNon-1.361.12-2.29-1.3188.170.809
32 CKB | E5a_E7a (S1) | NeuroMycAmp | NeuroMycNon-1.301.11-2.21-1.3188.130.809
33 CCDC57 | E18a_E19b (S0) | NeuroMycAmp | NeuroMycNon1.17-1.112.04-1.3387.610.809
34 STX8 | E5a_E7a (S1) | NeuroMycAmp | NeuroMycNon-2.511.26-4.53-1.3686.860.809
35 C19orf28 | E6a_E8a (S1) | NeuroMycAmp | NeuroMycNon1.061.142.38N/A86.560.809
36 PREPL | E15a_E17a (S2) | NeuroMycAmp | NeuroMycNon2.44-1.274.29-1.3985.970.809
37 ATXN2L | E22c_E22c (S0) | NeuroMycAmp | NeuroMycNon-1.19-1.18-2.71N/A85.590.809
38 L3MBTL | E20a_E21b (S3) | NeuroMycAmp | NeuroMycNon-1.50-1.24-3.49N/A85.480.809
39 TMEFF1 | E9a_E11a (S1) | NeuroMycAmp | NeuroMycNon1.32-1.152.16-1.4684.340.809
40 ARRB1 | E1a_E3a (S1) | NeuroMycAmp | NeuroMycNon-1.27-1.23-2.96N/A84.090.788
41 AARSD1 | E13b_E15a (S1) | NeuroMycAmp | NeuroMycNon1.561.313.84N/A83.430.809
42 HAUS4 | E6a_E8a (S1) | NeuroMycAmp | NeuroMycNon1.561.323.90N/A83.020.809
43 MPV17 | E8a_E8d (S0) | NeuroMycAmp | NeuroMycNon1.281.283.09N/A82.160.809
44 CSDE1 | E11a_E13a (S1) | NeuroMycAmp | NeuroMycNon-2.001.30-3.08-1.6181.110.809
45 MTMR15 | E3a_E5a (S2) | NeuroMycAmp | NeuroMycNon-2.431.40-3.84-1.6779.850.809
46 ZCCHC7 | E3a_E10a (S6) | NeuroMycAmp | NeuroMycNon1.521.494.28N/A78.360.619
47 IARS | E33b_E34b (S1) | NeuroMycAmp | NeuroMycNon1.251.403.32N/A78.210.637
48 PUM1 | E19a_E21a (S1) | NeuroMycAmp | NeuroMycNon-1.64-1.57-4.90N/A77.940.809
49 SEPT3 | E4a_E6a (S2) | NeuroMycAmp | NeuroMycNon-1.12-1.40-3.04N/A76.900.809
50 RP9P | E5a_E7a (S2) | NeuroMycAmp | NeuroMycNon-1.461.28-2.16-1.9375.870.637
51 MRPL18 | E1b_E3a (S3) | NeuroMycAmp | NeuroMycNon1.441.664.51N/A74.740.809
52 NME1-NME2 | E1a_E6a (S6) | NeuroMycAmp | NeuroMycNon1.731.906.29N/A74.170.809
53 RP1-34B21.1 | E3a_E5a (S1) | NeuroMycAmp | NeuroMycNon-2.141.51-2.92-2.2572.230.809
54 LRPPRC | E35a_E37a (S3) | NeuroMycAmp | NeuroMycNon1.211.894.37N/A69.890.406
55 AC093283.3 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon-1.41-6.98-18.51N/A60.040.809
56 NOP58 | E2a_E5a (S3) | NeuroMycAmp | NeuroMycNon-2.282.04-2.38-10.2054.900.809