Alternative expression values of the type: NovelJunction for comparison: NeuroMycAmp_vs_NeuroMycNon (abs(SI) value > 2)


Distribution of log2 SI values for comparison: NeuroMycAmp_vs_NeuroMycNon and data type: NovelJunction

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: NovelJunction. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed NovelJunction features

The following table provides a ranked list of alternatively expressed NovelJunction features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKNeuroMycAmp_vs_NeuroMycNon (Gene | Feature | Links)SIGene FCSeq FCReciprocity
(RI)
Percent Seq DE
(PFC)
q-value
1 AC093283.3 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon-1.41-6.98-18.51N/A60.040.809
2 NOP58 | E2a_E5a (S3) | NeuroMycAmp | NeuroMycNon-2.282.04-2.38-10.2054.900.809
3 NME1-NME2 | E1a_E6a (S6) | NeuroMycAmp | NeuroMycNon1.731.906.29N/A74.170.809
4 LRPPRC | E35a_E37a (S3) | NeuroMycAmp | NeuroMycNon1.211.894.37N/A69.890.406
5 MRPL18 | E1b_E3a (S3) | NeuroMycAmp | NeuroMycNon1.441.664.51N/A74.740.809
6 PUM1 | E19a_E21a (S1) | NeuroMycAmp | NeuroMycNon-1.64-1.57-4.90N/A77.940.809
7 RP1-34B21.1 | E3a_E5a (S1) | NeuroMycAmp | NeuroMycNon-2.141.51-2.92-2.2572.230.809
8 ZCCHC7 | E3a_E10a (S6) | NeuroMycAmp | NeuroMycNon1.521.494.28N/A78.360.619
9 MTMR15 | E3a_E5a (S2) | NeuroMycAmp | NeuroMycNon-2.431.40-3.84-1.6779.850.809
10 IARS | E33b_E34b (S1) | NeuroMycAmp | NeuroMycNon1.251.403.32N/A78.210.637
11 SEPT3 | E4a_E6a (S2) | NeuroMycAmp | NeuroMycNon-1.12-1.40-3.04N/A76.900.809
12 KCNQ2 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon4.03-1.3811.84-1.3088.470.809
13 HAUS4 | E6a_E8a (S1) | NeuroMycAmp | NeuroMycNon1.561.323.90N/A83.020.809
14 AARSD1 | E13b_E15a (S1) | NeuroMycAmp | NeuroMycNon1.561.313.84N/A83.430.809
15 CSDE1 | E11a_E13a (S1) | NeuroMycAmp | NeuroMycNon-2.001.30-3.08-1.6181.110.809
16 MPV17 | E8a_E8d (S0) | NeuroMycAmp | NeuroMycNon1.281.283.09N/A82.160.809
17 RP9P | E5a_E7a (S2) | NeuroMycAmp | NeuroMycNon-1.461.28-2.16-1.9375.870.637
18 PREPL | E15a_E17a (S2) | NeuroMycAmp | NeuroMycNon2.44-1.274.29-1.3985.970.809
19 STX8 | E5a_E7a (S1) | NeuroMycAmp | NeuroMycNon-2.511.26-4.53-1.3686.860.809
20 L3MBTL | E20a_E21b (S3) | NeuroMycAmp | NeuroMycNon-1.50-1.24-3.49N/A85.480.809
21 ARRB1 | E1a_E3a (S1) | NeuroMycAmp | NeuroMycNon-1.27-1.23-2.96N/A84.090.788
22 MANBAL | E1a_E2c (S0) | NeuroMycAmp | NeuroMycNon1.741.193.97N/A88.830.809
23 ZNF638 | E32b_E36b (S13) | NeuroMycAmp | NeuroMycNon2.321.185.89N/A91.330.809
24 ATXN2L | E22c_E22c (S0) | NeuroMycAmp | NeuroMycNon-1.19-1.18-2.71N/A85.590.809
25 AC022210.1 | E1a_E2c (S1) | NeuroMycAmp | NeuroMycNon2.761.167.84N/A93.380.809
26 TMEFF1 | E9a_E11a (S1) | NeuroMycAmp | NeuroMycNon1.32-1.152.16-1.4684.340.809
27 C19orf28 | E6a_E8a (S1) | NeuroMycAmp | NeuroMycNon1.061.142.38N/A86.560.809
28 CDC16 | E14a_E16a (S1) | NeuroMycAmp | NeuroMycNon1.711.143.71N/A91.130.458
29 GMIP | E17a_E19a (S1) | NeuroMycAmp | NeuroMycNon-1.42-1.13-3.02N/A90.310.809
30 TARBP1 | E18a_E20a (S1) | NeuroMycAmp | NeuroMycNon-2.551.12-5.22-1.1593.450.0678
31 C16orf42 | E4a_E6a (S1) | NeuroMycAmp | NeuroMycNon1.231.122.63N/A89.510.809
32 NUP54 | E3a_E10a (S6) | NeuroMycAmp | NeuroMycNon-1.361.12-2.29-1.3188.170.809
33 CKB | E5a_E7a (S1) | NeuroMycAmp | NeuroMycNon-1.301.11-2.21-1.3188.130.809
34 NCOR2 | E16a_E17a (S0) | NeuroMycAmp | NeuroMycNon-1.22-1.11-2.58N/A90.340.809
35 CCDC57 | E18a_E19b (S0) | NeuroMycAmp | NeuroMycNon1.17-1.112.04-1.3387.610.809
36 YJEFN3 | E4a_E8a (S5) | NeuroMycAmp | NeuroMycNon-1.88-1.10-4.07N/A93.360.809
37 MED24 | E24a_E26a (S1) | NeuroMycAmp | NeuroMycNon1.82-1.103.21-1.1892.490.458
38 TUBGCP6 | E15a_E16c (S1) | NeuroMycAmp | NeuroMycNon1.70-1.092.98-1.1892.390.809
39 MMS19 | E11c_E13a (S3) | NeuroMycAmp | NeuroMycNon-1.141.09-2.03-1.2689.560.809
40 MMS19 | E7a_E8a (S2) | NeuroMycAmp | NeuroMycNon2.041.094.47N/A94.780.809
41 CCDC150 | E24a_E25b (S0) | NeuroMycAmp | NeuroMycNon1.781.093.74N/A94.120.0678
42 C11orf30 | E6a_E8a (S2) | NeuroMycAmp | NeuroMycNon-1.111.08-2.00-1.2589.990.809
43 CENPE | E24a_E26a (S1) | NeuroMycAmp | NeuroMycNon1.75-1.083.13-1.1493.830.809
44 MKKS | E3a_E5a (S2) | NeuroMycAmp | NeuroMycNon-2.33-1.06-5.35N/A96.480.809
45 TMEM131 | E30a_E32a (S1) | NeuroMycAmp | NeuroMycNon1.86-1.063.43-1.1095.390.809
46 FDPS | E5b_E6a (S5) | NeuroMycAmp | NeuroMycNon1.471.062.95N/A94.820.458
47 PIGF | E1a_E1g (S0) | NeuroMycAmp | NeuroMycNon2.93-1.067.17-1.0697.090.156
48 NLGN2 | E1a_E3a (S1) | NeuroMycAmp | NeuroMycNon-1.63-1.05-3.26N/A95.770.809
49 NOL11 | E10a_E12a (S1) | NeuroMycAmp | NeuroMycNon1.39-1.052.50-1.1095.300.809
50 MYO19 | E25a_E27a (S1) | NeuroMycAmp | NeuroMycNon2.98-1.047.58-1.0497.950.809
51 ZC3H7A | E18a_E20a (S1) | NeuroMycAmp | NeuroMycNon1.291.042.55N/A95.720.809
52 RAC1 | E7a_E9a (S2) | NeuroMycAmp | NeuroMycNon2.54-1.035.63-1.0498.300.809
53 CCDC14 | E8a_E10a (S2) | NeuroMycAmp | NeuroMycNon1.501.022.90N/A98.040.809
54 RPAIN | E4a_E7a (S2) | NeuroMycAmp | NeuroMycNon1.261.012.42N/A98.910.809
55 SLC9A5 | E8a_E10a (S1) | NeuroMycAmp | NeuroMycNon-1.60-1.01-3.06N/A99.280.809
56 WDR27 | E25a_E27a (S1) | NeuroMycAmp | NeuroMycNon1.921.003.79N/A99.880.809