Alternative expression values of the type: Transcript for comparison: Pre_vs_Post (abs(SI) value > 2)


Distribution of log2 SI values for comparison: Pre_vs_Post and data type: Transcript

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: Transcript. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed Transcript features

The following table provides a ranked list of alternatively expressed Transcript features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPre_vs_Post (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 IGLV2-14 | ENST00000390312 | (Pre) | (Post)-1.107883.563666.33N/A47.77
2 AB019439.1 | ENST00000390614 | (Pre) | (Post)-1.103356.871561.81N/A47.53
3 AC110080.2 | ENST00000390259 | (Pre) | (Post)1.12-2628.29-1208.30N/A47.40
4 D87017.2 | ENST00000390329 | (Pre) | (Post)5.004.60147.00N/A76.58
5 AB019439.1 | ENST00000390619 | (Pre) | (Post)-1.1387.6440.12N/A45.21
6 APP | ENST00000357903 | (Pre) | (Post)1.45-64.38-23.52N/A43.12
7 RBM7 | ENST00000375490 | (Pre) | (Post)-1.61-6.85-20.95N/A61.26
8 IGLV2-23 | ENST00000390306 | (Pre) | (Post)-1.1441.4918.79N/A44.05
9 NR2F2 | ENST00000394166 | (Pre) | (Post)1.12-39.32-18.11N/A44.10
10 DHCR7 | ENST00000355527 | (Pre) | (Post)-1.45-6.25-17.09N/A60.77
11 IGKV2-26 | ENST00000401768 | (Pre) | (Post)1.25-39.63-16.67N/A43.33
12 PRRX1 | ENST00000367760 | (Pre) | (Post)1.83-55.13-15.55N/A40.63
13 BRCC3 | ENST00000369462 | (Pre) | (Post)3.881.0415.31N/A98.50
14 OXR1 | ENST00000336821 | (Pre) | (Post)2.162.9513.22N/A70.48
15 STX5 | ENST00000294179 | (Pre) | (Post)-3.05-1.34-11.13N/A89.13
16 RNF180 | ENST00000389100 | (Pre) | (Post)-1.10-5.18-11.11N/A59.41
17 BCL11A | ENST00000359629 | (Pre) | (Post)2.172.3310.53N/A73.54
18 CSGALNACT1 | ENST00000332246 | (Pre) | (Post)-1.41-3.53-9.35N/A63.95
19 BIRC5 | ENST00000350051 | (Pre) | (Post)1.403.408.99N/A64.19
20 C1orf188 | ENST00000289214 | (Pre) | (Post)-1.09-4.16-8.83N/A60.44
21 ENSA | ENST00000354702 | (Pre) | (Post)-3.181.05-8.65-1.0497.91
22 PITPNC1 | ENST00000335257 | (Pre) | (Post)-1.34-3.39-8.56N/A63.74
23 TNIP3 | ENST00000057513 | (Pre) | (Post)1.203.718.54N/A62.05
24 BMF | ENST00000397573 | (Pre) | (Post)2.511.478.35N/A84.70
25 C13orf3 | ENST00000400018 | (Pre) | (Post)2.201.707.79N/A79.47
26 CEPT1 | ENST00000357172 | (Pre) | (Post)-2.40-1.43-7.52N/A85.00
27 DNA2L | ENST00000399180 | (Pre) | (Post)1.772.187.42N/A71.98
28 SIRPB1 | ENST00000279477 | (Pre) | (Post)1.35-18.88-7.42N/A40.55
29 GDI2 | ENST00000380181 | (Pre) | (Post)2.90-1.027.33-1.0299.07
30 GTSE1 | ENST00000361934 | (Pre) | (Post)1.821.966.92N/A74.23
31 HLA-DMA | ENST00000395303 | (Pre) | (Post)-1.92-1.81-6.84N/A76.40
32 DNASE1L3 | ENST00000318316 | (Pre) | (Post)1.252.796.63N/A64.84
33 THOC7 | ENST00000295899 | (Pre) | (Post)-3.071.30-6.48-1.3287.78
34 HRASLS2 | ENST00000255695 | (Pre) | (Post)1.26-15.26-6.35N/A40.42
35 PTPRG | ENST00000295874 | (Pre) | (Post)1.43-16.63-6.19N/A39.34
36 FER1L3 | ENST00000371489 | (Pre) | (Post)-1.51-2.17-6.16N/A70.13
37 GABPB2 | ENST00000368916 | (Pre) | (Post)2.79-1.165.98-1.1892.46
38 RPS14 | ENST00000312037 | (Pre) | (Post)-2.891.24-5.96-1.2889.10
39 RBM4 | ENST00000398692 | (Pre) | (Post)2.151.325.90N/A86.35
40 LYRM7 | ENST00000334031 | (Pre) | (Post)-2.40-1.05-5.57N/A96.99
41 CDH1 | ENST00000261769 | (Pre) | (Post)1.362.175.56N/A68.94
42 MCM8 | ENST00000265187 | (Pre) | (Post)1.382.085.43N/A69.81
43 AEN | ENST00000379231 | (Pre) | (Post)1.751.615.43N/A78.05
44 RAB1A | ENST00000409784 | (Pre) | (Post)-2.761.26-5.35-1.3287.76
45 HMMR | ENST00000393915 | (Pre) | (Post)1.112.465.31N/A65.01
46 C10orf128 | ENST00000374156 | (Pre) | (Post)1.40-13.95-5.29N/A38.73
47 MCOLN3 | ENST00000370589 | (Pre) | (Post)3.45-2.075.27-2.5669.52
48 CECR1 | ENST00000262607 | (Pre) | (Post)-1.12-2.42-5.26N/A65.29
49 IVNS1ABP | ENST00000392007 | (Pre) | (Post)2.041.265.19N/A87.53
50 L3MBTL3 | ENST00000368139 | (Pre) | (Post)1.282.105.09N/A68.75
51 CHCHD1 | ENST00000372833 | (Pre) | (Post)1.491.815.08N/A73.24
52 UBA3 | ENST00000361055 | (Pre) | (Post)-2.371.06-4.90-1.0796.58
53 CD79B | ENST00000392795 | (Pre) | (Post)-1.65-1.56-4.88N/A78.18
54 TEX264 | ENST00000341333 | (Pre) | (Post)-1.67-1.53-4.87N/A78.85
55 IL2RG | ENST00000374202 | (Pre) | (Post)-1.21-2.07-4.80N/A68.31
56 CDC16 | ENST00000252458 | (Pre) | (Post)1.481.714.79N/A74.45
57 AC005921.3 | ENST00000240304 | (Pre) | (Post)2.141.084.78N/A95.21
58 CLDND1 | ENST00000341181 | (Pre) | (Post)-2.561.24-4.76-1.3287.78
59 NLRP2 | ENST00000263437 | (Pre) | (Post)1.212.014.65N/A68.70
60 VPS29 | ENST00000397678 | (Pre) | (Post)-2.391.15-4.55-1.2191.36
61 RPL34 | ENST00000394667 | (Pre) | (Post)-2.11-1.04-4.48N/A97.68
62 IGBP1 | ENST00000342206 | (Pre) | (Post)1.991.124.45N/A92.89
63 C6orf48 | ENST00000375638 | (Pre) | (Post)-1.61-1.43-4.39N/A80.42
64 EXOSC9 | ENST00000243498 | (Pre) | (Post)1.191.914.36N/A69.48
65 WBSCR1 | ENST00000265753 | (Pre) | (Post)1.771.274.33N/A86.05
66 SLAMF7 | ENST00000359331 | (Pre) | (Post)1.821.234.32N/A87.73
67 C12orf48 | ENST00000378128 | (Pre) | (Post)1.002.144.29N/A65.65
68 FCER1G | ENST00000289902 | (Pre) | (Post)1.681.344.27N/A83.36
69 CPNE8 | ENST00000331366 | (Pre) | (Post)-1.53-1.46-4.23N/A79.17
70 MAGOH | ENST00000371466 | (Pre) | (Post)1.521.464.19N/A79.13
71 CENPN | ENST00000299572 | (Pre) | (Post)1.711.264.13N/A86.06
72 TBRG1 | ENST00000375005 | (Pre) | (Post)-1.45-1.50-4.11N/A77.60
73 STAT1 | ENST00000409465 | (Pre) | (Post)1.061.974.11N/A67.49
74 CD44 | ENST00000278385 | (Pre) | (Post)1.05-8.48-4.10N/A39.75
75 RPS24 | ENST00000360830 | (Pre) | (Post)1.191.764.03N/A71.14
76 C1orf144 | ENST00000401089 | (Pre) | (Post)-1.70-1.24-4.03N/A86.63
77 HEATR1 | ENST00000366581 | (Pre) | (Post)1.891.073.97N/A95.10
78 RAP1B | ENST00000250559 | (Pre) | (Post)-1.91-1.04-3.91N/A96.98
79 CASP3 | ENST00000393588 | (Pre) | (Post)-2.781.77-3.89-2.4470.48
80 WIPF1 | ENST00000392547 | (Pre) | (Post)-1.11-1.79-3.85N/A69.95
81 PSMD13 | ENST00000352303 | (Pre) | (Post)1.101.793.83N/A69.74
82 DST | ENST00000361203 | (Pre) | (Post)1.98-1.043.79-1.0697.19
83 TNFSF13 | ENST00000293825 | (Pre) | (Post)-1.84-1.05-3.75N/A96.63
84 XPNPEP1 | ENST00000369658 | (Pre) | (Post)1.241.573.72N/A74.39
85 EIF4E2 | ENST00000258416 | (Pre) | (Post)1.141.673.67N/A71.73
86 DMTF1 | ENST00000331242 | (Pre) | (Post)1.691.133.66N/A91.19
87 SRI | ENST00000265729 | (Pre) | (Post)-1.30-1.47-3.61N/A76.97
88 RP11-369J21.6 | ENST00000372281 | (Pre) | (Post)2.03-1.143.59-1.2290.90
89 RAPGEF1 | ENST00000398415 | (Pre) | (Post)1.88-1.053.52-1.0796.59
90 TNFRSF10B | ENST00000347739 | (Pre) | (Post)-1.48-1.26-3.51N/A84.36
91 MORF4L1 | ENST00000331268 | (Pre) | (Post)-2.141.27-3.48-1.4783.98
92 ABCA5 | ENST00000320086 | (Pre) | (Post)1.591.153.46N/A90.10
93 SLC30A6 | ENST00000282587 | (Pre) | (Post)1.291.413.45N/A78.25
94 ZNF429 | ENST00000307355 | (Pre) | (Post)1.751.013.41N/A98.83
95 USP19 | ENST00000398888 | (Pre) | (Post)1.611.123.40N/A91.81
96 SEC23B | ENST00000336714 | (Pre) | (Post)-1.61-1.08-3.28N/A94.02
97 TGOLN2 | ENST00000282120 | (Pre) | (Post)-1.35-1.29-3.28N/A82.53
98 CWC22 | ENST00000295749 | (Pre) | (Post)-2.031.26-3.25-1.4983.65
99 RBM39 | ENST00000374039 | (Pre) | (Post)1.301.303.20N/A81.70
100 C4orf8 | ENST00000382839 | (Pre) | (Post)1.74-1.043.20-1.0796.59
101 DNAJC11 | ENST00000377577 | (Pre) | (Post)-1.721.04-3.17-1.0796.85
102 C14orf135 | ENST00000406854 | (Pre) | (Post)1.261.323.16N/A80.63
103 GSTK1 | ENST00000358406 | (Pre) | (Post)1.291.293.15N/A81.84
104 RPL31 | ENST00000264258 | (Pre) | (Post)1.081.463.08N/A74.75
105 DYNLT1 | ENST00000367089 | (Pre) | (Post)1.291.263.08N/A82.84
106 RNPS1 | ENST00000320225 | (Pre) | (Post)-1.921.24-3.05-1.4883.81
107 RBM12 | ENST00000401607 | (Pre) | (Post)-1.821.16-3.05-1.3088.45
108 C12orf35 | ENST00000381054 | (Pre) | (Post)2.15-1.463.05-2.0274.71
109 RIF1 | ENST00000336130 | (Pre) | (Post)1.041.483.04N/A73.84
110 EEF1G | ENST00000329251 | (Pre) | (Post)-1.41-1.13-3.00N/A90.16
111 KIAA0406 | ENST00000373447 | (Pre) | (Post)-1.791.15-2.99-1.3088.51
112 UBAP2 | ENST00000379238 | (Pre) | (Post)-1.44-1.10-2.98N/A92.25
113 MGLL | ENST00000398101 | (Pre) | (Post)1.83-1.202.97-1.4085.64
114 RPL27 | ENST00000253788 | (Pre) | (Post)-1.641.07-2.91-1.1493.84
115 HISPPD1 | ENST00000358359 | (Pre) | (Post)-1.32-1.15-2.88N/A88.26
116 DFFA | ENST00000377038 | (Pre) | (Post)1.321.162.88N/A87.90
117 MRPL35 | ENST00000409180 | (Pre) | (Post)1.201.252.88N/A82.52
118 TMEM201 | ENST00000340381 | (Pre) | (Post)-1.10-1.34-2.88N/A78.16
119 OCIAD2 | ENST00000381464 | (Pre) | (Post)1.041.382.84N/A76.26
120 MAN1A1 | ENST00000368468 | (Pre) | (Post)-1.27-1.17-2.83N/A86.77
121 PAIP2 | ENST00000265192 | (Pre) | (Post)-1.651.15-2.73-1.3287.91
122 H3F3A | ENST00000366813 | (Pre) | (Post)1.351.062.69N/A94.56
123 UBAP2L | ENST00000368504 | (Pre) | (Post)-1.421.02-2.63-1.0398.40
124 MAP3K8 | ENST00000375322 | (Pre) | (Post)1.341.032.60N/A97.35
125 HNRNPH1 | ENST00000356731 | (Pre) | (Post)1.151.152.55N/A87.27
126 PSPC1 | ENST00000338910 | (Pre) | (Post)1.081.202.54N/A83.63
127 CTNND1 | ENST00000399050 | (Pre) | (Post)1.45-1.082.53-1.1892.47
128 RPL30 | ENST00000287038 | (Pre) | (Post)-1.28-1.03-2.50N/A96.81
129 DOCK10 | ENST00000409802 | (Pre) | (Post)1.69-1.302.49-1.8077.71
130 RPL34 | ENST00000394668 | (Pre) | (Post)1.36-1.042.47-1.0896.22
131 YWHAB | ENST00000353703 | (Pre) | (Post)-1.611.26-2.43-1.6979.64
132 SON | ENST00000290239 | (Pre) | (Post)1.131.102.42N/A89.90
133 FGFR1OP2 | ENST00000229395 | (Pre) | (Post)1.051.172.42N/A84.68
134 RPS27L | ENST00000330964 | (Pre) | (Post)1.121.112.41N/A89.46
135 GABPB1 | ENST00000380877 | (Pre) | (Post)1.081.132.39N/A88.03
136 YLPM1 | ENST00000325680 | (Pre) | (Post)1.25-1.012.36-1.0299.01
137 NPM1 | ENST00000393820 | (Pre) | (Post)1.061.112.31N/A89.00
138 SEC24D | ENST00000379735 | (Pre) | (Post)-1.14-1.04-2.28N/A95.74
139 NDUFV2 | ENST00000318388 | (Pre) | (Post)-1.771.56-2.18-3.6863.60
140 PRCC | ENST00000271526 | (Pre) | (Post)-1.07-1.04-2.18N/A95.52
141 SEC24D | ENST00000280551 | (Pre) | (Post)-1.07-1.04-2.17N/A95.49
142 RAB2 | ENST00000262646 | (Pre) | (Post)-1.301.14-2.15-1.4285.33
143 SEC61G | ENST00000352861 | (Pre) | (Post)-1.811.63-2.15-4.5361.03
144 AC023024.6 | ENST00000254188 | (Pre) | (Post)1.12-1.012.15-1.0398.58
145 TNPO3 | ENST00000265388 | (Pre) | (Post)1.41-1.242.14-1.7878.07
146 HNRNPU | ENST00000283179 | (Pre) | (Post)-1.561.42-2.07-2.8667.45
147 FNBP1 | ENST00000355681 | (Pre) | (Post)1.24-1.142.07-1.4684.32