Brooks-Wilson Laboratory Genome Sciences Centre, BC Cancer Agency
Links
Selected Publications
- Rare and common variants in the Apolipoprotein E gene in healthy oldest old.
Tindale LC , Leach S, Ushey K, Daley D, Brooks-Wilson AR.
Neurobiol Aging. 35(3): 727.e1-3 (2014) PMID: 24126160
- Genetics of healthy aging and longevity.
Brooks-Wilson AR.
Hum Genet. 132(12):1323-38 (2013) PMID: 23925498
- Sex- and subtype-specific analysis of H2AFX polymorphisms in non-Hodgkin lymphoma.
Bretherick KL , Schuetz JM, Morton LM, Purdue MP, Conde L, Gallagher RP, Connors JM, Gascoyne RD, Berry BR, Armstrong B, Kricker A, Vajdic CM, Grulich A, Hjalgrim H, Smedby KE, Skibola CF, Rothman N, Spinelli JJ, Brooks-Wilson AR.
PLoS One. 8(9):e74619 (2013) PMID: 24069324
- Genetic polymorphisms at TIMP3 are associated with survival of adenocarcinoma of the gastroesophageal junction.
Bashash M , Shah A, Hislop G, Treml M, Bretherick K, Janoo-Gilani R, Leach S, Le N, Bajdik C, Brooks-Wilson AR.
PLoS One. 8(3):e59157 (2013) PMID: 23527119
- Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.
Earp M , Kelemen LE, Magliocco AM, Swenerton KD, Chenevix-Trench G; Australian Cancer Study; Australian Ovarian Cancer Study Group, Lu Y, Hein A, Ekici AB, Beckmann MW, Fasching PA,
Lambrechts D, Despierre E, Vergote I, Lambrechts S, Doherty JA, Rossing MA, Chang-Claude J, Rudolph A, Friel G, Moysich KB, Odunsi K, Sucheston-Campbell L, Lurie G, Goodman MT, Carney ME, Thompson PJ, Runnebaum IB,
Dürst M, Hillemanns P, Dörk T, Antonenkova N, Bogdanova N, Leminen A, Nevanlinna H, Pelttari LM, Butzow R, Bunker CH, Modugno F, Edwards RP, Ness RB, du Bois A, Heitz F, Schwaab I, Harter P, Karlan BY, Walsh C, Lester J,
Jensen A, Kjær SK, Høgdall CK, Høgdall E, Lundvall L, Sellers TA, Fridley BL, Goode EL, Cunningham JM, Vierkant RA, Giles GG, Baglietto L, Severi G, Southey MC, Liang D, Wu X, Lu K, Hildebrandt MA, Levine DA, Bisogna M,
Schildkraut JM, Iversen ES, Weber RP, Berchuck A, Cramer DW, Terry KL, Poole EM, Tworoger SS, Bandera EV, Chandran U, Orlow I, Olson SH, Wik E, Salvesen HB, Bjorge L, Halle MK, van Altena AM, Aben KK, Kiemeney LA, Massuger LF,
Pejovic T, Bean YT, Cybulski C, Gronwald J, Lubinski J, Wentzensen N, Brinton LA, Lissowska J, Garcia-Closas M, Dicks E, Dennis J, Easton DF, Song H, Tyrer JP, Pharoah PD, Eccles D, Campbell IG, Whittemore AS, McGuire V, Sieh W,
Rothstein JH, Flanagan JM, Paul J, Brown R, Phelan CM, Risch HA, McLaughlin JR, Narod SA, Ziogas A, Anton-Culver H, Gentry-Maharaj A, Menon U, Gayther SA, Ramus SJ, Wu AH, Pearce CL, Pike MC, Dansonka-Mieszkowska A, Rzepecka IK, Szafron LM, Kupryjanczyk J, Cook LS, Le ND, Brooks-Wilson AR; On behalf of the Ovarian Cancer Association Consortium.
Hum Genet. Epub ahead of print (2013) PMID: 24190013
- Inherited common variants in mitochondrial DNA and invasive serous epithelial ovarian cancer risk.
Earp MA ,Brooks-Wilson AR, Cook L, Le N.
BMC Res Notes. 6(1): 425 (2013) PMID: 24148579
- Non-Hodgkin lymphoma risk and variants in genes controlling lymphocyte development.
Schuetz JM, Daley D, Leach S, Conde L, Berry BR, Gallagher RP, Connors JM, Gascoyne RD, Bracci PM, Skibola CF, Spinelli JJ, Brooks-Wilson AR.
PLoS One. 8(9):e75170. (2013) PMID: 24098683
- Genetic variation in the NBS1, MRE11, RAD50 and BLM genes and susceptibility to non-Hodgkin lymphoma.
Schuetz JM , MaCarthur AC, Leach S, Lai AS, Gallagher RP, Connors JM, Gascoyne RD, Spinelli JJ, Brooks-Wilson AR.
BMC Med Genet. 10 pp. 117 (2009) PMID: 19917125
- A survey of genomic properties for the detection of regulatory polymorphisms.
Montgomery SB, Griffith OL, Schuetz JM, Brooks-Wilson A, Jones SJ.
PLoS Comput Biol. 3 pp. e106 (2007) PMID: 17559298
- Reduced telomere length variation in healthy oldest old.
Halaschek-Wiener J, Vulto I, Fornika D, Collins J, Connors JM, Le N, Lansdorp PM, Brooks-Wilson A.
Mech Ageing Dev 129(11):638-41. PMID: 18765247
- A systematic evaluation of the ataxia telangiectasia mutated gene does not show an association with non-Hodgkin lymphoma.
Sipahimalani P, Spinelli JS, MacArthur AC, Lai A, Leach SR, Janoo-Gilani RT, Palmquist DL, Connors JM, Gascoyne RD, Gallagher RP, Brooks-Wilson AR.
Int J Cancer 2007; In Press. PMID:
- Genetic variation in H2AFX contributes to risk of non-Hodgkin lymphoma.
Novik KL, Spinelli JS, MacArthur AC, Shumansky K, Sipahimalani P, Leach SR, Lai A, Connors JM, Gascoyne RD, Gallagher RP, Brooks-Wilson AR.
Cancer Epidemiology, Biomarkers and Prevention 2007; In Press. PMID:
- Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. Rothman N, Skibola CF, Wang SS, Morgan G, Lan Q, Smith MT, Spinelli JJ, Willett E, De Sanjose S, Cocco P, Berndt SI, Brennan P, Brooks-Wilson A, Wacholder S, Becker N, Hartge P, Zheng T, Roman E, Holly EA, Boffetta P, Armstrong B, Cozen W, Linet M, Bosch FX, Ennas MG, Holford TR, Gallagher RP, Rollinson S, Bracci PM, Cerhan JR, Whitby D, Moore PS, Leaderer B, Lai A, Spink C, Davis S, Bosch R, Scarpa A, Zhang Y, Severson RK, Yeager M, Chanock S, Nieters A.
Lancet Oncology 2005; 7: pp.27-38. PMID: 16389181.
- Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Halaschek-Wiener J, Khattra JS, McKay S, Pouzyrev A, Stott JM, Yang GS, Holt RA, Jones S, Marra MA, Brooks-Wilson AR and Riddle DL. Genome Research 2005 15: 603-615; originally published online Apr 18, 2005. PMID: 15837805
(PDF)
- Differential expression of a novel ankyrin
containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney. Anglesio MS, Evdokimova V, Melnyk N, Zhang L, Fernandez CV, Grundy PE, Leach
S, Marra MA, Brooks-Wilson AR, Penninger J and Sorensen P. Human Molecular Genetics, 2004, Vol. 13, No. 18 2061-2074. PMID: 15254018
(PDF)
- Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. Brooks-Wilson AR, Kaurah P, Suriano G, Leach S, Senz J, Grehan N, Butterfield YSN, Jeyes J, Schinas J, Bacani J, Kelsey M, Ferreira P, MacGillivray B, MacLeod P, Micek M, Ford J, Foulkes W, Australie K, Greenberg C, LaPointe M, Gilpin C, Nikkel S, Gilchrist D, Hughes R, Jackson CE, Monaghan KG, Oliveira MJ, Seruca R, Gallinger S, Caldas C and Huntsman D. Journal of Medical Genetics 2004; 41;508-517. PMID: 15235021
(PDF)
- The Genome Sequence of the SARS-Associated Coronavirus. Marra MA, Jones SJ, Astell CR, Holt RA, Brooks-Wilson A, Butterfield YS, Khattra J, Asano JK, Barber SA, Chan SY, Cloutier A, Coughlin SM, Freeman D, Girn N, Griffith OL, Leach SR, Mayo M, McDonald H, Montgomery SB, Pandoh PK, Petrescu AS, Robertson AG, Schein JE, Siddiqui A, Smailus DE, Stott JM, Yang GS, Plummer F, Andonov A, Artsob H, Bastien N, Bernard K, Booth TF, Bowness D, Czub M, Drebot M, Fernando L, Flick R, Garbutt M, Gray M, Grolla A, Jones S, Feldmann H, Meyers A, Kabani A, Li Y, Normand S, Stroher U, Tipples GA, Tyler S, Vogrig R, Ward D, Watson B, Brunham RC, Krajden M, Petric M, Skowronski DM, Upton C, Roper RL. Science, 2003 May 30;300(5624):1399-404. PMID: 12730501