Summary page for 'TNFRSF6B' (ENSG00000026036) - Project: Sutent


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Basic Gene Stats

Species: Human
Gene Name: 'TNFRSF6B' (HUGO: TNFRSF6B RTEL1)
ALEXA Gene ID: 464 (ALEXA_hs_53_36o)
EnsEMBL Gene ID: ENSG00000026036
Entrez Gene Record(s): TNFRSF6B RTEL1
Ensembl Gene Record: ENSG00000026036
Evidence: Known Gene
Gene Type: protein_coding
Location: chr20 61759607-61800495 (+): 20q13.3 20q13.3
Size (bp): 40889
Description: Tumor necrosis factor receptor superfamily member 6B Precursor (Decoy receptor for Fas ligand)(Decoy receptor 3)(DcR3)(M68) [Source:UniProtKB/Swiss-Prot;Acc:O95407]



Data links for each library (displays expression data in UCSC Genome Browser)

Sutent (2276 total reads for 'TNFRSF6B')
Control (1520 total reads for 'TNFRSF6B')



Link to other genes in the same chromosome region as 'TNFRSF6B'

chr20_15



Features defined for this gene: 1119

Gene: 1
Transcript: 10
ExonRegion: 51
Junction: 860
    KnownJunction: 40
    NovelJunction: 820
Boundary: 86
    KnownBoundary: 11
    NovelBoundary: 75
Intron: 37
ActiveIntronRegion: 25
SilentIntronRegion: 43
Intergenic: 2
ActiveIntergenicRegion: 4
SilentIntergenicRegion: 1



Summary of transcript specific features for 'TNFRSF6B' (ENSG00000026036)

ENST00000342852:E22a_E24a
ENST00000370006:NA
ENST00000356810:NA
ENST00000370018:NA
ENST00000360203:NA
ENST00000370003:ER25a
ENST00000369996:ER36a
ENST00000355223:NA
ENST00000369993:E36b_E38b
ENST00000318100:NA


Summary of known expressed features

LibraryExon Regions
(Expressed/Total)
Known Junctions
(Expressed/Total)
Sutent:46/5134/40
Control:47/5134/40


Normalized expression data for each known or novel expressed feature of 'TNFRSF6B'

The following table summarizes the expression values of all known features of the gene 'TNFRSF6B' in each library. Known features (i.e. those that correspond to one or more EnsEMBL transcripts) are included regardless of their expression level. Novel features are only reported in this table if they are expressed above the level of intergenic background noise. The 'FID' column reports the unique Feature ID for the gene, transcript, exon region, exon junction, etc. The 'Name' column reports the Feature Name for the feature (e.g. E5a_E6a is the name of an exon junction corresponding to the connection of exons 5 and 6). The 'Type' column reports the type of the feature and may be one of the following: Gene, Transcript, Exon Region, Known Junction, Novel Junction, Known Boundary, Novel Boundary, Silent or Active Intronic Regions, and Silent or Active Intergenic Regions (see our manuscript for more details). The 'Base Count' column reports the number of nucleotide bases for the feature followed by the percent of these that do NOT correspond to repeats and the percent that are known to be protein coding in one or more EnsEMBL transcripts. The 'Supporting ESTs/mRNAs' column reports the number of ESTs and mRNAs that when aligned to the human genome support the expression of a feature (i.e. the sequence alignment coordinates match an exon junction or boundaries of an exon, retained intron, etc.). The 'Conserved Species' column reports the number of 'other' species for which there was at least 1 supporting EST/mRNA alignment. Finally, the remaining columns report the log2 expression value for each feature in each library. Bold values indicate expression above background. Each expression value is also a hyperlink to a view of the feature's corresponding genomic region in the UCSC genome browser. Expression data will automatically be loaded as custom GFF and wiggle tracks.


FIDNameTypeBase Count
(% unmasked |
% coding)
Supporting
Human
ESTs/mRNAs
Conserved
Species
Sutent Log2
Expression
Control Log2
Expression
G464TNFRSF6BGene6384 (97% | 75%)N/AN/A6.666.17
T1269ENST00000370018TranscriptN/A (N/A% | N/A%)N/AN/ANANA
T1260ENST00000318100TranscriptN/A (N/A% | N/A%)N/AN/ANANA
T1264ENST00000360203TranscriptN/A (N/A% | N/A%)N/AN/ANANA
T1261ENST00000342852Transcript62 (100% | 100%)N/AN/A0.000.00
T1268ENST00000370006TranscriptN/A (N/A% | N/A%)N/AN/ANANA
T1262ENST00000355223TranscriptN/A (N/A% | N/A%)N/AN/ANANA
T1263ENST00000356810TranscriptN/A (N/A% | N/A%)N/AN/ANANA
T1267ENST00000370003Transcript122 (100% | 1%)N/AN/A2.270.43
T1266ENST00000369996Transcript93 (100% | 1%)N/AN/A7.347.75
T1265ENST00000369993Transcript62 (100% | 100%)N/AN/A0.000.00
ER142024ER1aExonRegion503 (88% | 0%)100.121.78
EB13352E1_AbKnownBoundary62 (100% | 0%)100.000.00
ER142025ER1bExonRegion154 (100% | 0%)614.094.78
EJ73117E1a_E2aKnownJunction62 (100% | 0%)1410.004.06
ER142026ER2aExonRegion171 (100% | 1%)1804.705.41
EB13355E2_AbKnownBoundary62 (100% | 50%)2125.696.48
ER142027ER2bExonRegion101 (100% | 100%)2385.105.53
EJ73159E2a_E3aKnownJunction62 (100% | 100%)2225.495.44
ER142028ER3aExonRegion199 (100% | 100%)1225.215.72
EJ73199E3a_E4aKnownJunction62 (100% | 100%)1134.686.11
ER142029ER4aExonRegion94 (100% | 100%)10114.935.92
EJ73238E4a_E5aKnownJunction62 (100% | 100%)8115.735.39
ER142030ER5aExonRegion82 (100% | 100%)955.425.50
EJ73276E5a_E6aKnownJunction62 (100% | 100%)956.296.16
ER142031ER6aExonRegion61 (100% | 100%)785.835.69
EJ73313E6a_E7aKnownJunction62 (100% | 100%)735.765.38
ER142032ER7aExonRegion76 (100% | 100%)856.075.54
EJ73349E7a_E8aKnownJunction62 (100% | 100%)845.795.30
ER142033ER8aExonRegion85 (100% | 100%)885.795.66
EJ73384E8a_E9aKnownJunction62 (100% | 100%)886.304.68
ER142034ER9aExonRegion66 (100% | 100%)876.355.82
EJ73418E9a_E10aKnownJunction62 (100% | 100%)886.335.72
ER142035ER10aExonRegion154 (69% | 100%)655.285.08
EJ73451E10a_E11aKnownJunction62 (50% | 100%)855.335.43
ER142036ER11aExonRegion39 (100% | 100%)866.145.42
EJ73483E11a_E12aKnownJunction62 (100% | 100%)865.925.49
ER142037ER12aExonRegion79 (100% | 100%)965.405.22
EJ73514E12a_E13aKnownJunction62 (100% | 100%)936.395.49
SIN155149I12_SR1SilentIntronRegion493 (35% | 0%)003.214.12
ER142038ER13aExonRegion98 (100% | 100%)1066.015.81
EJ73544E13a_E14aKnownJunction62 (100% | 100%)1056.225.67
ER142039ER14aExonRegion56 (100% | 100%)955.265.44
EJ73573E14a_E15aKnownJunction62 (87% | 100%)945.395.52
ER142040ER15aExonRegion75 (31% | 100%)1025.755.51
EJ73601E15a_E16aKnownJunction62 (50% | 100%)1025.995.03
ER142041ER16aExonRegion82 (100% | 100%)1055.875.42
EJ73628E16a_E17aKnownJunction62 (100% | 100%)1055.414.98
IN105713I16Intron1765 (96% | 0%)003.494.42
SIN155155I16_SR1SilentIntronRegion1323 (95% | 0%)003.374.34
AIN123733I16_AR1ActiveIntronRegion440 (100% | 0%)303.794.65
EB13384E17_AaNovelBoundary62 (100% | 50%)104.155.38
ER142042ER17aExonRegion133 (100% | 100%)995.615.75
EJ73654E17a_E18aKnownJunction62 (100% | 100%)966.866.02
ER142043ER18aExonRegion114 (100% | 100%)1066.015.42
EJ73679E18a_E19aKnownJunction62 (100% | 100%)1255.093.96
ER142044ER19aExonRegion41 (100% | 100%)1255.044.58
EJ73703E19a_E20aKnownJunction62 (100% | 100%)1344.264.99
ER142045ER20aExonRegion86 (100% | 100%)1385.605.48
EJ73726E20a_E21aKnownJunction62 (100% | 100%)1955.395.80
ER142046ER21aExonRegion78 (100% | 100%)1665.635.49
EJ73748E21a_E22aKnownJunction62 (100% | 100%)1844.704.17
ER142047ER22aExonRegion78 (100% | 100%)1945.424.39
EJ73769E22a_E23aKnownJunction62 (100% | 100%)1555.573.16
EJ73770E22a_E24aKnownJunction62 (100% | 100%)500.000.00
ER142048ER23aExonRegion147 (100% | 100%)1275.375.18
EJ73789E23a_E24aKnownJunction62 (100% | 100%)1394.665.37
ER142049ER24aExonRegion116 (100% | 100%)17115.075.16
EJ73809E24a_E25bKnownJunction62 (100% | 100%)1595.405.81
ER142050ER25aExonRegion122 (100% | 1%)302.270.43
EB13402E25_AbKnownBoundary62 (100% | 50%)403.350.00
ER142051ER25bExonRegion123 (100% | 100%)1645.975.58
EJ73826E25a_E26aKnownJunction62 (100% | 100%)1615.735.82
ER142052ER26aExonRegion148 (97% | 100%)1305.805.24
EJ73842E26a_E27aKnownJunction62 (95% | 100%)1826.283.38
ER142053ER27aExonRegion143 (100% | 100%)1636.285.66
EJ73857E27a_E28aKnownJunction62 (100% | 100%)1715.884.71
ER142054ER28aExonRegion96 (100% | 100%)1726.185.31
EJ73871E28a_E29aKnownJunction62 (100% | 100%)1615.595.50
ER142055ER29aExonRegion199 (100% | 100%)1756.195.66
EJ73884E29a_E30aKnownJunction62 (100% | 100%)1956.956.30
ER142056ER30aExonRegion141 (100% | 100%)1515.985.54
EJ73896E30a_E31aKnownJunction62 (100% | 100%)1315.654.74
ER142057ER31aExonRegion117 (100% | 100%)1336.476.03
EJ73907E31a_E32aKnownJunction62 (100% | 100%)1416.455.94
ER142058ER32aExonRegion234 (100% | 100%)1015.835.93
EJ73917E32a_E33aKnownJunction62 (100% | 100%)1516.376.56
ER142059ER33aExonRegion156 (100% | 100%)1416.286.23
EJ73926E33a_E34aKnownJunction62 (100% | 100%)1516.486.89
ER142060ER34aExonRegion153 (100% | 100%)1216.035.88
EB13421E34_DaKnownBoundary62 (100% | 100%)414.964.27
EJ73934E34a_E35aKnownJunction62 (100% | 100%)905.785.38
ER142061ER34bExonRegion170 (100% | 100%)414.824.38
EJ73941E34b_E35aKnownJunction62 (100% | 100%)424.014.06
ER142062ER35aExonRegion77 (100% | 100%)726.355.46
EB13425E35_DaKnownBoundary62 (100% | 56%)717.026.17
EJ73949E35a_E36bKnownJunction62 (100% | 100%)503.353.38
ER142063ER35bExonRegion394 (100% | 1%)205.684.67
ER142064ER35cExonRegion5 (100% | 0%)200.000.00
EB13426E36_AaNovelBoundary62 (100% | 0%)205.525.50
ER142065ER36aExonRegion93 (100% | 1%)607.347.75
EB13428E36_AbKnownBoundary62 (100% | 50%)1005.414.30
EB13430E36_AcKnownBoundary62 (100% | 63%)1214.903.38
ER142066ER36bExonRegion8 (100% | 100%)1526.325.01
ER142067ER36cExonRegion295 (100% | 100%)1528.327.82
EB13429E36_DaKnownBoundary62 (100% | 100%)1899.518.19
ER142068ER36dExonRegion43 (100% | 100%)1898.927.65
EB13431E36_DbKnownBoundary62 (100% | 100%)1798.037.45
EJ73971E36b_E38bKnownJunction62 (100% | 100%)000.000.00
ER142069ER36eExonRegion85 (100% | 100%)1768.798.31
EB13427E36_DcNovelBoundary62 (100% | 50%)005.844.72
EJ73972E36c_E37aKnownJunction62 (100% | 100%)1858.908.12
EJ73973E36c_E38aNovelJunction62 (100% | 100%)005.050.00
IN105733I36Intron136 (100% | 0%)004.643.58
SIN155175I36_SR1SilentIntronRegion134 (100% | 0%)004.663.60
EB13432E37_AaNovelBoundary62 (100% | 50%)005.455.90
ER142070ER37aExonRegion195 (100% | 100%)1359.038.32
EJ73975E37a_E38aKnownJunction62 (100% | 100%)1518.647.86
IN105734I37Intron757 (100% | 0%)006.145.58
AIN123744I37_AR1ActiveIntronRegion154 (100% | 0%)106.195.21
SIN155176I37_SR1SilentIntronRegion10 (100% | 0%)006.006.18
AIN123745I37_AR2ActiveIntronRegion474 (100% | 0%)106.265.70
SIN155177I37_SR2SilentIntronRegion115 (100% | 0%)005.515.46
EB13434E38_AaNovelBoundary62 (100% | 50%)006.075.45
ER142071ER38aExonRegion202 (100% | 100%)318.707.78
EB13435E38_AbKnownBoundary62 (100% | 100%)1357.976.48
ER142072ER38bExonRegion80 (100% | 100%)127.696.76
EB13436E38_DaKnownBoundary62 (100% | 53%)1108.937.39
ER142073ER38cExonRegion123 (93% | 2%)007.966.82
ER142074ER38dExonRegion14 (100% | 0%)000.000.00


Figures displaying gene and feature expression levels in each library

The following figures illustrate the expression of the gene 'TNFRSF6B' and its component features for each library. First the expression values are displayed for only the exons and known (or expressed novel) exon junctions. This first display consists of a single plot with one colored line per library (as indicated in the legend). Next, the expression of the gene relative to the distribution of all gene expression values is displayed as a histogram. In these figures (one for each library) the expression of the current gene is indicated by a dotted red line. Estimated cutoffs for background expression level corresponding to intergenic and intragenic noise are indicated by dotted black lines. The bar plots following these histograms display the expression level of all individual features. The color of the bars correspond to different feature types (enumerated as colored boxes in the legend). As in the histograms, the estimated cutoffs level for intergenic and intragenic noise are indicated as dotted lines. For genes with low expression values, these cutoffs converge to a single value. *If you can not see the figure below, click here