Alternative expression values of the type: KnownBoundary for comparison: PC9_IR_vs_DMSO (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PC9_IR_vs_DMSO and data type: KnownBoundary

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: KnownBoundary. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed KnownBoundary features

The following table provides a ranked list of alternatively expressed KnownBoundary features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPC9_IR_vs_DMSO (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 CTNNB1 | E18_Ab | (PC9_IR) | (PC9_DMSO)3.29-1.168.40-1.1593.46
2 C20orf117 | E16_Da | (PC9_IR) | (PC9_DMSO)-3.071.50-5.58-1.6280.89
3 KIF2C | E23_Da | (PC9_IR) | (PC9_DMSO)2.84-1.425.06-1.5582.34
4 MED22 | E4_Da | (PC9_IR) | (PC9_DMSO)2.79-1.534.50-1.7977.86
5 GMPPA | E12_Da | (PC9_IR) | (PC9_DMSO)-2.781.00-6.82-1.0099.81
6 C22orf13 | E7_Dc | (PC9_IR) | (PC9_DMSO)-2.701.08-6.01-1.0995.89
7 DIDO1 | E8_Dc | (PC9_IR) | (PC9_DMSO)2.69-1.006.44-1.0099.93
8 SETD6 | E2_Da | (PC9_IR) | (PC9_DMSO)2.651.127.03N/A94.49
9 SLCO4A1 | E9_Ab | (PC9_IR) | (PC9_DMSO)-2.54-1.19-6.93N/A91.59
10 CRI2 | E1_Ad | (PC9_IR) | (PC9_DMSO)-2.531.00-5.77-1.0099.81
11 SEC16A | E6_Da | (PC9_IR) | (PC9_DMSO)-2.53-1.07-6.19N/A96.28
12 NEFH | E4_Da | (PC9_IR) | (PC9_DMSO)-2.43-1.03-5.55N/A98.15
13 TMBIM4 | E1_Ab | (PC9_IR) | (PC9_DMSO)2.401.538.11N/A83.05
14 SUV420H1 | E13_Da | (PC9_IR) | (PC9_DMSO)2.37-1.054.95-1.0697.29
15 GART | E12_Da | (PC9_IR) | (PC9_DMSO)-2.34-1.59-8.02N/A81.83
16 ARL6IP4 | E2_Dc | (PC9_IR) | (PC9_DMSO)-2.33-1.31-6.60N/A87.37
17 WASH1 | E16_Da | (PC9_IR) | (PC9_DMSO)2.281.055.10N/A97.11
18 RBAK | E7_Dc | (PC9_IR) | (PC9_DMSO)2.271.225.89N/A89.78
19 ZNF841 | E5_Ab | (PC9_IR) | (PC9_DMSO)2.241.758.27N/A79.09
20 TOR2A | E3_Dc | (PC9_IR) | (PC9_DMSO)-2.23-1.36-6.38N/A85.75
21 WAPAL | E1_Ad | (PC9_IR) | (PC9_DMSO)2.211.155.31N/A92.39
22 PPP2CB | E1_Ab | (PC9_IR) | (PC9_DMSO)2.19-1.403.25-1.8177.69
23 PHC2 | E15_Db | (PC9_IR) | (PC9_DMSO)-2.18-1.23-5.60N/A89.12
24 MOSPD3 | E3_Ad | (PC9_IR) | (PC9_DMSO)2.141.396.13N/A84.58
25 C6orf150 | E5_Ab | (PC9_IR) | (PC9_DMSO)-2.12-1.25-5.43N/A88.45
26 HP1BP3 | E6_Da | (PC9_IR) | (PC9_DMSO)2.101.486.34N/A82.59
27 FAM91A1 | E3_Da | (PC9_IR) | (PC9_DMSO)-2.07-1.22-5.12N/A89.15
28 SNRPB2 | E7_Da | (PC9_IR) | (PC9_DMSO)2.071.124.71N/A93.01
29 PHF6 | E10_Ab | (PC9_IR) | (PC9_DMSO)2.061.174.90N/A90.82
30 SUCLG1 | E1_Ab | (PC9_IR) | (PC9_DMSO)2.051.094.53N/A94.44
31 MSI2 | E2_Ab | (PC9_IR) | (PC9_DMSO)2.051.737.16N/A78.15
32 NME1-NME2 | E7_Da | (PC9_IR) | (PC9_DMSO)-2.04-1.29-5.32N/A86.65
33 PISD | E12_Db | (PC9_IR) | (PC9_DMSO)2.031.245.06N/A88.41
34 ESNA1 | E15_Ab | (PC9_IR) | (PC9_DMSO)2.011.204.82N/A89.56
35 RUSC1 | E8_Ab | (PC9_IR) | (PC9_DMSO)1.99-1.153.46-1.2590.11
36 RABGAP1L | E15_Da | (PC9_IR) | (PC9_DMSO)1.981.827.18N/A76.62
37 ZNF776 | E3_Ad | (PC9_IR) | (PC9_DMSO)1.961.405.47N/A83.42
38 COQ6 | E2_Ab | (PC9_IR) | (PC9_DMSO)1.961.174.53N/A90.66
39 TMEM102 | E1_Da | (PC9_IR) | (PC9_DMSO)1.921.274.77N/A86.89
40 MBD4 | E2_Da | (PC9_IR) | (PC9_DMSO)-1.911.23-3.03-1.4784.05
41 POLR1B | E10_Da | (PC9_IR) | (PC9_DMSO)-1.90-1.57-5.88N/A79.67
42 RBM33 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.901.043.87N/A97.49
43 METTL5 | E6_Ab | (PC9_IR) | (PC9_DMSO)1.89-1.342.77-1.8077.80
44 UNC84A | E8_Ab | (PC9_IR) | (PC9_DMSO)1.881.244.55N/A87.70
45 BMPR2 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.851.686.06N/A77.71
46 EIF4E2 | E1_Ae | (PC9_IR) | (PC9_DMSO)-1.84-1.04-3.72N/A97.09
47 ZFX | E11_Dc | (PC9_IR) | (PC9_DMSO)1.831.495.29N/A80.66
48 FBXL15 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.811.294.53N/A85.64
49 BTN3A1 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.812.227.79N/A71.97
50 OSBP2 | E17_Dc | (PC9_IR) | (PC9_DMSO)-1.79-2.00-6.93N/A73.59
51 MGAT4A | E17_Da | (PC9_IR) | (PC9_DMSO)1.791.364.72N/A83.34
52 HP1BP3 | E7_Ab | (PC9_IR) | (PC9_DMSO)1.781.485.08N/A80.68
53 PTPRU | E8_Dc | (PC9_IR) | (PC9_DMSO)1.781.705.85N/A76.85
54 RELA | E12_Da | (PC9_IR) | (PC9_DMSO)-1.77-1.02-3.47N/A98.74
55 LAMB1 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.721.334.41N/A83.75
56 C2orf30 | E14_Db | (PC9_IR) | (PC9_DMSO)1.721.294.23N/A85.10
57 CHD1L | E9_Da | (PC9_IR) | (PC9_DMSO)-1.70-1.53-4.98N/A79.03
58 ZNF776 | E3_Ac | (PC9_IR) | (PC9_DMSO)1.691.404.53N/A81.74
59 XPO5 | E34_Db | (PC9_IR) | (PC9_DMSO)-1.68-2.31-7.37N/A70.50
60 UGCGL1 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.67-1.152.76-1.3287.75
61 SAT1 | E2_Db | (PC9_IR) | (PC9_DMSO)1.661.875.88N/A73.98
62 HSPG2 | E76_Ab | (PC9_IR) | (PC9_DMSO)1.641.875.83N/A73.82
63 DVL1 | E7_Da | (PC9_IR) | (PC9_DMSO)-1.63-1.91-5.93N/A73.31
64 IER3 | E1_Dc | (PC9_IR) | (PC9_DMSO)-1.62-5.03-15.45N/A62.90
65 FMR1 | E18_Ab | (PC9_IR) | (PC9_DMSO)1.621.193.65N/A88.21
66 CREB3L2 | E3_Ab | (PC9_IR) | (PC9_DMSO)1.612.016.13N/A72.23
67 ATP2A3 | E23_Ab | (PC9_IR) | (PC9_DMSO)1.612.236.79N/A70.47
68 AMFR | E14_Af | (PC9_IR) | (PC9_DMSO)-1.571.16-2.57-1.3786.60
69 INTS6 | E1_Da | (PC9_IR) | (PC9_DMSO)1.55-1.032.84-1.0697.36
70 PSMG3 | E4_Da | (PC9_IR) | (PC9_DMSO)-1.54-1.79-5.22N/A73.94
71 HIBCH | E17_Da | (PC9_IR) | (PC9_DMSO)1.541.755.10N/A74.39
72 GLOD4 | E4_Ac | (PC9_IR) | (PC9_DMSO)-1.53-1.03-2.98N/A97.22
73 FBXO18 | E6_Ab | (PC9_IR) | (PC9_DMSO)1.521.073.06N/A94.25
74 SERINC1 | E3_Ab | (PC9_IR) | (PC9_DMSO)1.511.373.92N/A81.21
75 WBP1 | E5_Da | (PC9_IR) | (PC9_DMSO)1.511.333.80N/A82.24
76 OBFC2A | E7_Da | (PC9_IR) | (PC9_DMSO)1.503.339.44N/A65.10
77 RPL31 | E2_Dc | (PC9_IR) | (PC9_DMSO)1.491.845.20N/A72.92
78 TSPAN14 | E13_Db | (PC9_IR) | (PC9_DMSO)-1.49-1.67-4.70N/A75.01
79 TMF1 | E15_Ac | (PC9_IR) | (PC9_DMSO)1.481.554.32N/A77.00
80 PDPR | E20_Da | (PC9_IR) | (PC9_DMSO)-1.48-1.07-2.99N/A93.82
81 SNX21 | E4_Db | (PC9_IR) | (PC9_DMSO)1.461.604.40N/A75.88
82 AP1S3 | E7_Da | (PC9_IR) | (PC9_DMSO)1.461.283.51N/A83.61
83 SAT1 | E2_Dc | (PC9_IR) | (PC9_DMSO)1.451.875.09N/A72.30
84 LTBP3 | E27_Da | (PC9_IR) | (PC9_DMSO)-1.44-1.31-3.56N/A82.48
85 LPHN2 | E34_Dc | (PC9_IR) | (PC9_DMSO)1.441.694.58N/A74.30
86 SYTL2 | E7_Ac | (PC9_IR) | (PC9_DMSO)1.442.175.87N/A69.56
87 LSMD1 | E1_Ab | (PC9_IR) | (PC9_DMSO)-1.421.16-2.30-1.4484.83
88 SH3BP5 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.421.834.90N/A72.39
89 IPO5 | E29_Da | (PC9_IR) | (PC9_DMSO)1.42-1.312.04-2.2272.56
90 N4BP2L2 | E6_Da | (PC9_IR) | (PC9_DMSO)1.421.584.21N/A75.92
91 KIAA0652 | E18_Da | (PC9_IR) | (PC9_DMSO)-1.41-1.14-3.03N/A89.43
92 YPEL5 | E6_Da | (PC9_IR) | (PC9_DMSO)1.402.336.18N/A68.24
93 MUC4 | E2_Ae | (PC9_IR) | (PC9_DMSO)1.391.493.90N/A77.44
94 SLC31A1 | E5_Da | (PC9_IR) | (PC9_DMSO)-1.38-1.20-3.11N/A86.41
95 ERCC5 | E1_Da | (PC9_IR) | (PC9_DMSO)1.371.894.89N/A71.38
96 NFKBIZ | E7_Da | (PC9_IR) | (PC9_DMSO)1.362.506.40N/A66.98
97 C1orf43 | E1_Ad | (PC9_IR) | (PC9_DMSO)-1.35-1.13-2.87N/A89.86
98 SCOTIN | E6_Db | (PC9_IR) | (PC9_DMSO)-1.341.03-2.46-1.0796.77
99 PFKL | E7_Da | (PC9_IR) | (PC9_DMSO)-1.34-1.15-2.91N/A88.43
100 STK4 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.33-1.052.41-1.1195.18
101 QRSL1 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.331.253.14N/A83.53
102 LLGL2 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.332.105.27N/A69.10
103 CAV1 | E3_Da | (PC9_IR) | (PC9_DMSO)1.311.022.53N/A98.13
104 MCFD2 | E8_Da | (PC9_IR) | (PC9_DMSO)-1.31-1.17-2.89N/A87.34
105 PRKD3 | E2_Ab | (PC9_IR) | (PC9_DMSO)1.311.253.10N/A83.31
106 MRPS16 | E3_Da | (PC9_IR) | (PC9_DMSO)-1.30-1.49-3.67N/A76.45
107 TUBA1 | E5_Ab | (PC9_IR) | (PC9_DMSO)-1.29-1.68-4.11N/A73.24
108 ZMYM3 | E2_Ac | (PC9_IR) | (PC9_DMSO)1.281.243.01N/A83.78
109 SFRS5 | E8_Da | (PC9_IR) | (PC9_DMSO)1.282.034.91N/A69.27
110 GPR137 | E8_Da | (PC9_IR) | (PC9_DMSO)-1.28-1.16-2.80N/A87.58
111 MYO6 | E36_Da | (PC9_IR) | (PC9_DMSO)1.272.536.10N/A66.09
112 ATN1 | E6_Ac | (PC9_IR) | (PC9_DMSO)-1.27-1.06-2.54N/A94.50
113 RABEP1 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.261.273.03N/A82.50
114 PEA15 | E6_Da | (PC9_IR) | (PC9_DMSO)-1.26-1.37-3.28N/A78.99
115 HFE | E3_Da | (PC9_IR) | (PC9_DMSO)1.251.844.38N/A70.70
116 CCDC115 | E1_Da | (PC9_IR) | (PC9_DMSO)1.241.523.59N/A75.28
117 PTMA | E2_Ad | (PC9_IR) | (PC9_DMSO)1.241.062.49N/A94.42
118 ATXN10 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.241.162.74N/A86.97
119 IDH3B | E6_Da | (PC9_IR) | (PC9_DMSO)-1.23-1.21-2.84N/A84.32
120 PCK2 | E1_Ab | (PC9_IR) | (PC9_DMSO)-1.22-3.52-8.19N/A62.59
121 XPO5 | E34_Dc | (PC9_IR) | (PC9_DMSO)-1.21-2.31-5.34N/A66.72
122 TK1 | E7_Ab | (PC9_IR) | (PC9_DMSO)-1.20-1.51-3.46N/A75.07
123 FILIP1L | E7_Da | (PC9_IR) | (PC9_DMSO)1.191.743.99N/A71.34
124 TMSL3 | E1_Ab | (PC9_IR) | (PC9_DMSO)-1.181.13-2.00-1.4484.66
125 EEF1A1 | E9_Ab | (PC9_IR) | (PC9_DMSO)-1.181.04-2.17-1.1194.97
126 NOP2 | E17_Ab | (PC9_IR) | (PC9_DMSO)-1.17-1.42-3.21N/A76.81
127 CUL4B | E4_Ab | (PC9_IR) | (PC9_DMSO)1.161.814.06N/A70.19
128 FALZ | E22_Ac | (PC9_IR) | (PC9_DMSO)1.161.302.90N/A80.44
129 BAT2 | E3_Da | (PC9_IR) | (PC9_DMSO)-1.16-1.42-3.17N/A76.79
130 TFPI | E1_Ab | (PC9_IR) | (PC9_DMSO)1.161.623.61N/A72.75
131 YME1L1 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.15-1.072.08-1.2191.48
132 AHSA2 | E1_Db | (PC9_IR) | (PC9_DMSO)1.142.796.16N/A63.93
133 TRIM24 | E12_Da | (PC9_IR) | (PC9_DMSO)1.141.473.23N/A75.33
134 RHOC | E7_Dc | (PC9_IR) | (PC9_DMSO)-1.13-1.21-2.63N/A83.74
135 ABHD11 | E4_Da | (PC9_IR) | (PC9_DMSO)1.112.024.35N/A67.67
136 ROD1 | E17_Db | (PC9_IR) | (PC9_DMSO)1.111.082.33N/A91.69
137 IKZF2 | E11_Da | (PC9_IR) | (PC9_DMSO)1.102.304.92N/A65.67
138 AFTPH | E10_Db | (PC9_IR) | (PC9_DMSO)1.091.352.89N/A77.80
139 AC005921.3 | E11_Da | (PC9_IR) | (PC9_DMSO)1.092.124.52N/A66.67
140 GYG1 | E8_Da | (PC9_IR) | (PC9_DMSO)-1.09-1.42-3.02N/A75.84
141 CDKN1B | E3_Da | (PC9_IR) | (PC9_DMSO)1.091.713.64N/A70.55
142 FNBP1L | E1_Ab | (PC9_IR) | (PC9_DMSO)1.081.543.26N/A73.22
143 AP1S3 | E1_Ac | (PC9_IR) | (PC9_DMSO)1.081.282.70N/A80.16
144 TRAPPC3 | E6_Da | (PC9_IR) | (PC9_DMSO)-1.07-1.04-2.18N/A95.66
145 PTPRK | E43_Da | (PC9_IR) | (PC9_DMSO)1.071.322.76N/A78.60
146 GNE | E12_Ab | (PC9_IR) | (PC9_DMSO)1.061.503.13N/A73.75
147 HNRNPU | E14_Da | (PC9_IR) | (PC9_DMSO)-1.06-1.43-2.97N/A75.27
148 PSMD8 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.06-1.032.02-1.0896.37
149 MYO19 | E15_Da | (PC9_IR) | (PC9_DMSO)-1.05-1.84-3.82N/A68.63
150 AC010333.7 | E4_Da | (PC9_IR) | (PC9_DMSO)1.041.022.10N/A97.08
151 IL1RL1 | E10_Da | (PC9_IR) | (PC9_DMSO)-1.04-2.69-5.51N/A63.32
152 GABRE | E4_Ab | (PC9_IR) | (PC9_DMSO)-1.0311.635.69N/A41.46
153 PTPRU | E7_Ab | (PC9_IR) | (PC9_DMSO)1.031.703.48N/A70.09
154 PHLDB2 | E24_Db | (PC9_IR) | (PC9_DMSO)-1.03-1.98-4.05N/A67.18
155 MOBKL3 | E2_Ab | (PC9_IR) | (PC9_DMSO)1.021.232.49N/A81.70
156 MAPK3 | E7_Dc | (PC9_IR) | (PC9_DMSO)1.021.412.86N/A75.34
157 IDH3B | E6_Ab | (PC9_IR) | (PC9_DMSO)-1.01-1.21-2.45N/A82.20
158 FOSL2 | E5_Da | (PC9_IR) | (PC9_DMSO)1.011.342.70N/A77.15
159 PYCR2 | E7_Da | (PC9_IR) | (PC9_DMSO)-1.01-2.13-4.29N/A65.76
160 PCDH7 | E1_Ab | (PC9_IR) | (PC9_DMSO)1.013.456.92N/A60.99
161 C20orf30 | E1_Ad | (PC9_IR) | (PC9_DMSO)1.011.172.35N/A84.44
162 RGL2 | E20_Ab | (PC9_IR) | (PC9_DMSO)1.001.783.55N/A68.84
163 YWHAZ | E11_Da | (PC9_IR) | (PC9_DMSO)-1.00-1.16-2.31N/A85.31