Alternative expression values of the type: Transcript for comparison: PostTx_vs_PreTx (abs(SI) value > 2)


Distribution of log2 SI values for comparison: PostTx_vs_PreTx and data type: Transcript

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: Transcript. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed Transcript features

The following table provides a ranked list of alternatively expressed Transcript features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKPostTx_vs_PreTx (Gene | Feature | Links)SIGene FCSeq FCReciprocityPercent Seq DE
1 RANGRF | ENST00000226105 | (PostTx) | (PreTx)2.811.228.54N/A91.58
2 TSC22D3 | ENST00000372390 | (PostTx) | (PreTx)2.791.268.74N/A90.24
3 TAF5L | ENST00000366676 | (PostTx) | (PreTx)2.65-1.055.99-1.0697.26
4 TGOLN2 | ENST00000409353 | (PostTx) | (PreTx)2.52-1.444.00-1.7079.33
5 HNRNPK | ENST00000376256 | (PostTx) | (PreTx)2.45-1.433.83-1.7378.94
6 PTMA | ENST00000410064 | (PostTx) | (PreTx)2.44-1.035.28-1.0398.45
7 ZDHHC18 | ENST00000374141 | (PostTx) | (PreTx)-2.37-1.16-6.00N/A92.32
8 ZNF410 | ENST00000324593 | (PostTx) | (PreTx)2.331.045.21N/A97.67
9 FKBP1A | ENST00000381719 | (PostTx) | (PreTx)2.32-1.303.85-1.4883.82
10 EWSR1 | ENST00000333395 | (PostTx) | (PreTx)2.311.045.19N/A97.55
11 ANKMY1 | ENST00000373320 | (PostTx) | (PreTx)2.271.396.69N/A85.32
12 UBA1 | ENST00000377271 | (PostTx) | (PreTx)2.25-1.074.47-1.0995.90
13 PSMD1 | ENST00000409643 | (PostTx) | (PreTx)-2.25-1.67-7.93N/A80.24
14 RSRC2 | ENST00000331738 | (PostTx) | (PreTx)-2.171.12-4.04-1.1792.68
15 ASL | ENST00000304874 | (PostTx) | (PreTx)2.171.466.55N/A83.27
16 PEO1 | ENST00000370228 | (PostTx) | (PreTx)-2.15-1.18-5.23N/A90.93
17 ID2 | ENST00000331129 | (PostTx) | (PreTx)2.12-1.143.81-1.2191.22
18 TPM3 | ENST00000368545 | (PostTx) | (PreTx)2.12-1.433.02-1.9675.47
19 NSUN5 | ENST00000252594 | (PostTx) | (PreTx)2.111.084.65N/A95.34
20 FAM21C | ENST00000374359 | (PostTx) | (PreTx)2.09-1.103.87-1.1593.36
21 GNLY | ENST00000409932 | (PostTx) | (PreTx)2.091.456.17N/A82.94
22 PSD4 | ENST00000409656 | (PostTx) | (PreTx)2.04-1.043.93-1.0696.95
23 ARHGAP25 | ENST00000409202 | (PostTx) | (PreTx)-2.03-1.47-6.00N/A82.32
24 ZMIZ1 | ENST00000334512 | (PostTx) | (PreTx)-2.02-1.77-7.18N/A77.52
25 POR | ENST00000265302 | (PostTx) | (PreTx)-2.00-1.10-4.38N/A94.14
26 MBP | ENST00000397868 | (PostTx) | (PreTx)1.961.023.94N/A98.88
27 FAM98A | ENST00000238823 | (PostTx) | (PreTx)-1.95-1.50-5.80N/A81.27
28 XPNPEP1 | ENST00000369658 | (PostTx) | (PreTx)1.941.104.24N/A93.66
29 FLYWCH2 | ENST00000396958 | (PostTx) | (PreTx)-1.94-1.12-4.29N/A93.02
30 C10orf76 | ENST00000311122 | (PostTx) | (PreTx)-1.94-1.35-5.17N/A84.51
31 BCL2L13 | ENST00000399777 | (PostTx) | (PreTx)-1.93-1.49-5.65N/A81.36
32 CST3 | ENST00000376925 | (PostTx) | (PreTx)-1.90-6.47-24.07N/A63.01
33 MAP2K2 | ENST00000394867 | (PostTx) | (PreTx)1.89-1.113.36-1.1892.35
34 GGPS1 | ENST00000282841 | (PostTx) | (PreTx)1.89-1.183.14-1.3487.28
35 HMGB1 | ENST00000399489 | (PostTx) | (PreTx)1.88-1.123.31-1.2091.53
36 SEC31A | ENST00000311785 | (PostTx) | (PreTx)-1.87-1.85-6.77N/A75.71
37 CD37 | ENST00000391859 | (PostTx) | (PreTx)1.851.174.21N/A90.37
38 HP1BP3 | ENST00000375003 | (PostTx) | (PreTx)1.851.073.84N/A95.49
39 SIDT1 | ENST00000264852 | (PostTx) | (PreTx)-1.85-1.64-5.91N/A78.17
40 LPIN1 | ENST00000396098 | (PostTx) | (PreTx)1.821.254.42N/A86.81
41 SLC37A4 | ENST00000357590 | (PostTx) | (PreTx)1.801.033.57N/A98.06
42 PYCR2 | ENST00000345037 | (PostTx) | (PreTx)1.79-1.272.71-1.6480.44
43 HNRNPH1 | ENST00000329433 | (PostTx) | (PreTx)1.771.224.16N/A87.96
44 MPPE1 | ENST00000399978 | (PostTx) | (PreTx)1.771.244.20N/A87.15
45 FAM44A | ENST00000382426 | (PostTx) | (PreTx)1.76-1.312.58-1.8177.61
46 CKLF | ENST00000351137 | (PostTx) | (PreTx)1.741.434.78N/A81.32
47 LST1 | ENST00000376096 | (PostTx) | (PreTx)1.731.123.72N/A91.82
48 USP47 | ENST00000305481 | (PostTx) | (PreTx)-1.72-1.27-4.21N/A85.59
49 RASSF4 | ENST00000374411 | (PostTx) | (PreTx)1.711.133.72N/A91.34
50 MTA1 | ENST00000405646 | (PostTx) | (PreTx)1.701.625.26N/A77.49
51 CSNK2B | ENST00000409525 | (PostTx) | (PreTx)1.701.093.54N/A93.55
52 TTLL3 | ENST00000383827 | (PostTx) | (PreTx)1.701.183.82N/A89.09
53 EXOC7 | ENST00000405575 | (PostTx) | (PreTx)-1.63-1.08-3.36N/A93.88
54 MLLT10 | ENST00000377059 | (PostTx) | (PreTx)1.62-1.042.96-1.0796.65
55 NCOA4 | ENST00000344348 | (PostTx) | (PreTx)-1.60-1.23-3.73N/A86.47
56 NT5C2 | ENST00000369853 | (PostTx) | (PreTx)1.591.073.24N/A94.48
57 SERF2 | ENST00000409960 | (PostTx) | (PreTx)1.591.213.63N/A87.25
58 SNRPB | ENST00000336808 | (PostTx) | (PreTx)1.581.193.57N/A88.01
59 MAT2A | ENST00000409017 | (PostTx) | (PreTx)1.561.053.09N/A96.19
60 FYB | ENST00000351578 | (PostTx) | (PreTx)-1.55-2.35-6.91N/A69.31
61 HNRNPA1 | ENST00000330752 | (PostTx) | (PreTx)1.54-1.122.61-1.2689.81
62 SRP9 | ENST00000304786 | (PostTx) | (PreTx)-1.541.22-2.39-1.5881.63
63 TETRAN | ENST00000329687 | (PostTx) | (PreTx)1.541.323.84N/A82.88
64 GSTK1 | ENST00000378173 | (PostTx) | (PreTx)1.521.203.46N/A86.96
65 TXNDC11 | ENST00000283033 | (PostTx) | (PreTx)-1.52-1.28-3.66N/A84.05
66 ELOVL5 | ENST00000370913 | (PostTx) | (PreTx)1.50-1.152.44-1.3886.15
67 IL32 | ENST00000008180 | (PostTx) | (PreTx)-1.49-2.00-5.63N/A71.32
68 FBLN1 | ENST00000262722 | (PostTx) | (PreTx)1.49-17.22-6.14N/A38.93
69 HMGB1 | ENST00000339872 | (PostTx) | (PreTx)1.48-1.122.50-1.2789.23
70 IL6 | ENST00000401651 | (PostTx) | (PreTx)1.482.677.45N/A67.16
71 PPP1R11 | ENST00000376772 | (PostTx) | (PreTx)-1.46-1.55-4.27N/A76.90
72 ABI3BP | ENST00000383691 | (PostTx) | (PreTx)1.46-7.97-2.89N/A33.86
73 UBA1 | ENST00000377269 | (PostTx) | (PreTx)1.46-1.072.58-1.1493.67
74 TSC1 | ENST00000403810 | (PostTx) | (PreTx)1.461.463.99N/A78.67
75 VRK3 | ENST00000377011 | (PostTx) | (PreTx)-1.45-1.05-2.88N/A95.42
76 SF3B1 | ENST00000409915 | (PostTx) | (PreTx)1.451.514.13N/A77.45
77 KLHL6 | ENST00000392602 | (PostTx) | (PreTx)1.451.343.66N/A81.62
78 MRRF | ENST00000373728 | (PostTx) | (PreTx)1.451.393.78N/A80.24
79 SMARCAL1 | ENST00000358207 | (PostTx) | (PreTx)-1.45-1.35-3.69N/A81.16
80 CSNK2B | ENST00000375864 | (PostTx) | (PreTx)1.431.092.95N/A92.54
81 ACOT9 | ENST00000379303 | (PostTx) | (PreTx)-1.431.21-2.22-1.6580.36
82 RAP1B | ENST00000393436 | (PostTx) | (PreTx)1.431.133.04N/A90.02
83 COQ4 | ENST00000372875 | (PostTx) | (PreTx)1.421.233.29N/A85.41
84 PFKP | ENST00000381072 | (PostTx) | (PreTx)1.421.022.72N/A98.41
85 CUL4B | ENST00000371323 | (PostTx) | (PreTx)-1.41-1.42-3.77N/A79.03
86 C20orf6 | ENST00000401775 | (PostTx) | (PreTx)-1.41-1.70-4.49N/A73.98
87 TAPBP | ENST00000395114 | (PostTx) | (PreTx)1.39-1.172.24-1.5083.36
88 TIMP1 | ENST00000218388 | (PostTx) | (PreTx)1.39-7.98-3.05N/A34.91
89 PRDM10 | ENST00000304538 | (PostTx) | (PreTx)1.381.744.51N/A73.17
90 BUB3 | ENST00000407911 | (PostTx) | (PreTx)1.371.102.83N/A91.83
91 SUPT7L | ENST00000406540 | (PostTx) | (PreTx)1.361.594.09N/A75.23
92 HYOU1 | ENST00000404233 | (PostTx) | (PreTx)-1.36-1.44-3.71N/A78.13
93 QRICH1 | ENST00000395443 | (PostTx) | (PreTx)1.351.082.74N/A93.30
94 PPP1R12B | ENST00000367269 | (PostTx) | (PreTx)-1.34-2.30-5.84N/A67.95
95 TIAL1 | ENST00000369087 | (PostTx) | (PreTx)1.341.393.52N/A79.24
96 ACP1 | ENST00000272065 | (PostTx) | (PreTx)-1.34-1.00-2.54N/A99.64
97 MICAL1 | ENST00000368952 | (PostTx) | (PreTx)1.331.503.76N/A76.61
98 RPS27 | ENST00000368565 | (PostTx) | (PreTx)1.331.243.11N/A84.08
99 MS4A1 | ENST00000389939 | (PostTx) | (PreTx)1.321.824.56N/A71.68
100 ACP1 | ENST00000272067 | (PostTx) | (PreTx)-1.32-1.00-2.51N/A99.64
101 KBTBD3 | ENST00000393121 | (PostTx) | (PreTx)1.321.323.30N/A81.01
102 SCARA5 | ENST00000354914 | (PostTx) | (PreTx)1.31-8.61-3.47N/A36.64
103 POSTN | ENST00000379749 | (PostTx) | (PreTx)-1.29-4.90-11.99N/A61.00
104 U2AF1 | ENST00000380276 | (PostTx) | (PreTx)-1.28-1.29-3.16N/A81.64
105 TIAL1 | ENST00000369086 | (PostTx) | (PreTx)1.281.393.38N/A78.70
106 FCRL2 | ENST00000368178 | (PostTx) | (PreTx)1.282.345.65N/A67.13
107 MGEA5 | ENST00000370094 | (PostTx) | (PreTx)1.271.182.86N/A86.12
108 AGXT2L2 | ENST00000393488 | (PostTx) | (PreTx)1.271.774.28N/A71.73
109 SFRS7 | ENST00000378857 | (PostTx) | (PreTx)1.261.403.35N/A78.14
110 RPL32 | ENST00000396953 | (PostTx) | (PreTx)1.261.513.61N/A75.61
111 LTBP4 | ENST00000396819 | (PostTx) | (PreTx)-1.26-1.64-3.93N/A73.33
112 NIT1 | ENST00000368007 | (PostTx) | (PreTx)1.261.463.47N/A76.84
113 TEX264 | ENST00000341333 | (PostTx) | (PreTx)-1.25-1.23-2.93N/A83.83
114 PRPF38B | ENST00000370024 | (PostTx) | (PreTx)1.241.383.25N/A78.66
115 ARL6IP4 | ENST00000392433 | (PostTx) | (PreTx)1.241.383.26N/A78.54
116 PABPN1 | ENST00000397276 | (PostTx) | (PreTx)1.231.774.13N/A71.41
117 CD72 | ENST00000378430 | (PostTx) | (PreTx)1.212.084.81N/A68.20
118 CMTM7 | ENST00000349718 | (PostTx) | (PreTx)1.202.285.25N/A66.82
119 RAPGEF1 | ENST00000398415 | (PostTx) | (PreTx)1.191.062.42N/A93.86
120 JARID1A | ENST00000399787 | (PostTx) | (PreTx)-1.19-1.34-3.06N/A79.13
121 WDR45 | ENST00000376361 | (PostTx) | (PreTx)1.191.312.98N/A80.17
122 KIAA0907 | ENST00000368319 | (PostTx) | (PreTx)1.191.784.05N/A70.80
123 DDR2 | ENST00000367921 | (PostTx) | (PreTx)-1.19-3.50-7.97N/A62.35
124 POLR3D | ENST00000397802 | (PostTx) | (PreTx)1.19-1.002.27-1.0099.96
125 RANBP1 | ENST00000331821 | (PostTx) | (PreTx)-1.18-1.14-2.58N/A88.05
126 MPZL1 | ENST00000392121 | (PostTx) | (PreTx)-1.17-2.60-5.86N/A64.96
127 NADK | ENST00000378625 | (PostTx) | (PreTx)-1.17-1.13-2.54N/A88.70
128 HTR3A | ENST00000355556 | (PostTx) | (PreTx)1.172.325.24N/A66.28
129 HMGB1 | ENST00000326004 | (PostTx) | (PreTx)1.17-1.122.02-1.3786.37
130 BUB3 | ENST00000368858 | (PostTx) | (PreTx)-1.171.10-2.05-1.3088.59
131 IVNS1ABP | ENST00000392007 | (PostTx) | (PreTx)1.171.423.18N/A76.82
132 CNN2 | ENST00000348419 | (PostTx) | (PreTx)-1.17-2.00-4.49N/A68.40
133 MAP3K8 | ENST00000375321 | (PostTx) | (PreTx)1.162.515.62N/A65.19
134 C19orf60 | ENST00000397217 | (PostTx) | (PreTx)1.161.182.64N/A85.45
135 COPEB | ENST00000380946 | (PostTx) | (PreTx)1.161.413.14N/A77.06
136 PPM1M | ENST00000323588 | (PostTx) | (PreTx)1.151.212.70N/A83.66
137 C20orf199 | ENST00000326677 | (PostTx) | (PreTx)1.142.224.89N/A66.61
138 ABI3BP | ENST00000273339 | (PostTx) | (PreTx)1.14-7.97-3.62N/A38.27
139 RPS6 | ENST00000380381 | (PostTx) | (PreTx)1.131.884.09N/A69.12
140 TMSB4X | ENST00000380636 | (PostTx) | (PreTx)1.121.142.47N/A87.30
141 AC010987.1 | ENST00000355848 | (PostTx) | (PreTx)1.121.713.71N/A70.95
142 RBM3 | ENST00000354480 | (PostTx) | (PreTx)1.111.292.80N/A80.09
143 PPP2R1B | ENST00000341980 | (PostTx) | (PreTx)-1.11-1.25-2.69N/A81.83
144 ELAC2 | ENST00000338034 | (PostTx) | (PreTx)-1.11-1.51-3.25N/A74.17
145 BTBD9 | ENST00000403056 | (PostTx) | (PreTx)-1.11-1.76-3.78N/A70.29
146 CD6 | ENST00000313421 | (PostTx) | (PreTx)-1.11-1.47-3.16N/A75.01
147 C3orf17 | ENST00000314400 | (PostTx) | (PreTx)1.101.202.57N/A84.11
148 AC005921.3 | ENST00000311571 | (PostTx) | (PreTx)1.102.044.36N/A67.38
149 DIABLO | ENST00000267169 | (PostTx) | (PreTx)1.091.042.23N/A94.91
150 UBE2A | ENST00000371569 | (PostTx) | (PreTx)1.091.022.17N/A97.59
151 SSR1 | ENST00000244763 | (PostTx) | (PreTx)-1.09-1.45-3.08N/A75.17
152 CD58 | ENST00000369489 | (PostTx) | (PreTx)1.071.954.09N/A67.92
153 ZFAND5 | ENST00000376962 | (PostTx) | (PreTx)-1.07-1.87-3.92N/A68.64
154 ARHGEF1 | ENST00000391981 | (PostTx) | (PreTx)1.051.463.03N/A74.48
155 CD72 | ENST00000378431 | (PostTx) | (PreTx)1.052.084.30N/A66.57
156 PPM1G | ENST00000344034 | (PostTx) | (PreTx)-1.04-1.41-2.90N/A75.63
157 SFRS11 | ENST00000370949 | (PostTx) | (PreTx)1.041.513.11N/A73.27
158 YPEL3 | ENST00000398841 | (PostTx) | (PreTx)1.041.332.73N/A77.92
159 SAT1 | ENST00000379253 | (PostTx) | (PreTx)1.031.032.11N/A96.38
160 ASH1L | ENST00000392403 | (PostTx) | (PreTx)-1.03-1.37-2.79N/A76.69
161 NFYA | ENST00000353205 | (PostTx) | (PreTx)-1.03-1.22-2.49N/A82.07
162 KIAA1191 | ENST00000298569 | (PostTx) | (PreTx)-1.03-1.27-2.59N/A79.93
163 NPHP3 | ENST00000326682 | (PostTx) | (PreTx)1.012.384.77N/A64.35
164 ATF4 | ENST00000337304 | (PostTx) | (PreTx)1.001.543.10N/A72.24
165 HNRNPH2 | ENST00000316594 | (PostTx) | (PreTx)-1.00-1.10-2.20N/A89.40
166 PLXND1 | ENST00000324093 | (PostTx) | (PreTx)-1.00-2.87-5.74N/A62.39