No information is available about this cell line except that it is an immortalized kidney cell line
No information is available about this cell line except that it is a immortalized lung cell line
Indicated to be from a 57 year old female patient in ATCC and from a 61 year old in DSMZ
A cell line, now termed GNE-587170 (CVCL_AT69), was mistakenly distributed by OCI to a number of groups under the designation OCI-Ly-3, the origin of that cell line is now known
Not directly described in the original publication (PubMed=15372243), but indirectly mentioned ('Three others cell lines progressed in tissue culture')
Misclassified. Originally thought to be a myeloma cell line and to be a sister line to KMS-21-PE (CVCL_A445) but this does not seem to be the case (PubMed=12592342; PubMed=20143388).
Indicated as originating from colon in PubMed=8806092 and in ATCC, from lung in PubMed=11030152 and CCLE
We are not certain that NCI-H322 and NCI-H322M are identical
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: Amelogenin: X,Y->X
Contaminated. Grand-parent cell line (U-118MG) has been shown to be a U-138MG derivative.
Contaminated. Shown to be a Hutu 80 derivative (see JCRB web site).
Contaminated. Shown to be a HeLa derivative (CCRID; PubMed=26116706; PubMed=28851942). Originally thought to be a gastric adenocarcinoma.
According to DSMZ from a 46 year old female and from ascite fluids while archive documents of Moore G.E. indicate a 50 year old female and from a pleural effusion
Contaminated. Shown to be a RPMI-8226 derivative (ECACC). Originally thought to originate from the peripheral blood of a 57 year old female patient with chronic myelogenous leukemia.
Contaminated. Shown to be a HeLa derivative (PubMed=26116706). Originally thought to originate from a 32 year old female patient with a lung adenocarcinoma.
Indicated by Riken to originate from Okabe T. but with no reference provided. Therefore it is not certain that HLC-1 from Riken and HLC-1 originating from Akagi T. and Kimoto T. (PubMed=140093) are identical
Contaminated. Shown to be a HPAC derivative (PubMed=20143388). Originally thought to originate from a 74 year old male patient with a moderately differentiated adenocarcinoma of the head of the pancreas.
No information is available about this cell line except that it is an immortalized epithelial central nervous system cell line
Possibly contaminated. May be identical to OC 314 (CVCL_1616) according to STR profiling done at ICLC and to MSI data (PubMed=15677628).
After JCRB found out that KKU-M156 and KKU-M214 were derived from KKU-M213, these three cell lines were renamed by the lab which established them: KKU-M213 became KKU-213A, KKU-M214 became KKU-M213B and KKU-M156 became KKU-M213C (PubMed=32207095)
While the tumor has been shown to be HPV16 positive (PubMed=17112776), the cell line seems to be HPV16 negative (DSMZ)
Contaminated. Shown to be a SW480 derivative (PubMed=288927; PubMed=20143388). Originally thought to originate from a 70 year old female patient with a metastatic breast carcinoma.
Indicated to derive from a female patient in PubMed=1355757, but has a X,Y amelogenin STR marker
The results of the Sequenom MassARRAY used in PubMed=32567790 contradicts the whole exome sequencing data for BRAF and indicates a p.Val600Lys (c.1798_1799delGTinsAA) variant
Contaminated. The contaminant is not known. Seems to be a mixture of cell lines. Originally said to originate from a 60 year old male patient with a rectal carcinoma.
Misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (PubMed=16643607; PubMed=20143388). Originally thought to originate from a casein-producing breast cell line from a 27 year old Caucasian woman. In addition contains SV40 genomic sequence while the cell line was deemed to be spontaneously immortalized.
Removed from DepMap;
Contaminated. Shown to be a OVCAR-3 derivative (PubMed=20143388). Originally thought to originate from a 49 year old female patient with a thyroid gland papillary carcinoma.
Indicated to be from a 41 year old female patient in PubMed=7714613, from a 59 year old in PubMed=10083766 and from a 55 year old in PubMed=18261772
Contaminated. Shown to be a U-343MGa derivative (PubMed=22570425). Originally thought to originate from the brain of a 55 year old patient with a mixed astro-oligodendroglioma (grade II/III).
Contaminated. Shown to be a MCF-7 derivative (PubMed=18304946; PubMed=20143388).
TP53 mutation indicated incorrectly as being at c.742C>T in PubMed=10536175 and PubMed=20557307
Contaminated. Shown to be a HL-60 derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from a 38 year old female patient with acute nonlymphocytic leukemia.
Probably misclassified. Originally thought to be a leukemia cell line but is probably a B-lymphoblastoid cell line (PubMed=12592342).
Misclassified. Originally thought to be a neuroblastoma cell line but shown to be from an Askin tumor (PubMed=20143388).
Contaminated. Shown to be a U-138MG derivative (PubMed=20143388).
Misclassified. Originally thought to be a rhabdomyosarcoma cell line but shown to be from an Ewing sarcoma (PubMed=10379870; PubMed=12606131; PubMed=14697648).
A TP53 mutation is indicated as being at p.Ala138Pro (c.412G>C) in PubMed=17363600 but has not been confirmed by CCLE and Cosmic-CLP
Misidentified. This cell line is not the original glioblastoma cell line established in 1968 at the University of Uppsala. As described in PubMed=27582061 it is most probably also a glioblastoma cell line but whose origin is unknow. See U-87MG Uppsala (CVCL_GP63) for the original U-87MG cell line.
There seems to be two distinct cell lines which were assigned NCBI_Iran catalog number C427
TP53 mutation indicated incorrectly as being at c.452C>T in PubMed=1764370
Misclassified. Originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line (PubMed=8382007).
TP53 mutation indicated incorrectly as being at c.818G>A in PubMed=1630814
Removed from DepMap;
Misclassified. Originally thought to be an ovarian granulosa cell tumor but seems to be a small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) (PubMed=33328126).
While it was indicated to be EBV-positive (PubMed=20454443), this result has later been shown to be invalid (personal communication of Uphoff C.C.)
Contaminated. Shown to be a T24 derivative (ICLAC). Originally thought to originate from a clear cell renal cell carcinoma.
Contaminated. Shown to be a LN-992 derivative (PubMed=22570425).
NRAS mutation indicated incorrectly as being p.Gly12Ser in PubMed=9379676
Additional TP53 mutation in c.815T>C indicated incorrectly in PubMed=1630814
Misclassified. Originally thought to be a mucinous gastric adenocarcinoma cell line from a 52 year old male patient but is a B-lymphoblastoid cell line (DSMZ; PubMed=30285677).
Was originally published as originating from a small cell lung carcinoma (PubMed=2985257), but was later shown to originate from a prostate small cell carcinoma (PubMed=2569043)
TP53 mutation indicated incorrectly as being at c.542G>A in PubMed=1630814
Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be an acute myeloid leukemia cell line (PubMed=29533902).
TP53 mutation indicated to be on p.Arg175His (c.524G>A) in PubMed=10071127
Was incorrectly indicated to have an EWSR1-FLI1 (EWS-FLI1) gene fusion in PubMed=23637631
TP53 mutation indicated incorrectly as being at c.818G>A in PubMed=1630814
Misclassified. Originally thought to be a clear cell renal cell carcinoma but shown to be from a papillary renal cell carcinoma (PubMed=17409424; PubMed=27993170).
Contaminated. Shown to be a RCC4 derivative (ICLAC).
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: CSF1PO: 11,12->12, D18S51: 17->17,21 and D8S1179: 8,13->13,15
Removed from DepMap;
Was indicated not to have a TP53 mutation in PubMed=1370612 and PubMed=15900046
The reported STR profile from CLS of this cell line was changed in June 2019. Seven conflicts with other sources were resolved
Misclassified. Originally described as originating from an adenocarcinoma of liver and thus classified as hepatocellular carcinoma. Later studies show that it most probably has arisen from endothelial cells (PubMed=1371504; PubMed=31938418).
Indicated to have a TP53 p.Arg158Leu (c.473G>T) mutation according to PubMed=1311061, but no TP53 mutation detected according to PubMed=20557307, CCLE and Cosmic-CLP
TP53 mutation indicated incorrectly as being at p.Tyr327His (c.981T>C) in PubMed=8136267
This cell line is said to originate from a 'renal leiomyoblastoma'. This is an antiquated/imprecise terminology that can not be assigned to a precise cancer type. As there is no information on the exact origin of this cell line, except that it was deposited by Peebles P.T at ATCC, we have assigned it to the generic 'kidney neoplasm' of NCIt
Partially contaminated. Some ATCC stocks were cross-contaminated by K-562 initially (PubMed=7759961). The problem was corrected and subsequent stocks have been confirmed to carry only U-937.
Removed from DepMap;
Misidentified/contaminated. Shown to be identical to MEL-Wei. This cell line was reported to be isogenic with LCL-Ho (CVCL_1868) but it does not have the same STR profile (PubMed=10508494; PubMed=20143388). According to DSMZ ACC-62 it is a human female cell line.
Was originally classified a thyroid gland papillary carcinoma (PTC) but is now considered to be a poorly differentiated thyroid gland carcinoma (PDTC) (PubMed=23162534)
FLC-4 (CVCL_D204) is often stated to be synonymous with JHH-4, but a FLC-4 patent reference (Patent=US5804441) seems to indicate that it is derived from JHH-4 and has a different karyotype
Contaminated. Shown to be a ME-180 derivative (PubMed=22570425).
KRAS mutation indicated incorrectly as being p.Gly12Val in PubMed=12037578
Additional TP53 mutation in c.793C>T indicated incorrectly in PubMed=1630814
Indicated in PubMed=11921276 as originating from an adenocarcinoma of the rectosigmoid part of the intestine, but is only indicated in the oldest publication (DOI=10.1007/978-1-4757-1647-4_5) as a colon adenocarcinoma
Misclassified. Originally thought to be a colon adenocarcinoma cell line but shown to be from a Melanoma (PubMed=25926053).
Additional TP53 mutation in c.818G>A indicated incorrectly in PubMed=1630814
Possibly misclassified. It is not certain that this cell line originate from a alveolar rhabdomyosarcoma (ARMS). It lacks the PAXA3-FOXO1 gene fusion characteristics of ARMS. Many papers classify it as an embryonal rhabdomyosarcoma (ERMS) and we accordingly describe it as such.
Partially contaminated. Some JCRB stocks were found to be from mouse (PubMed=20143388). Stock bought in 2013 was shown to be human by exome sequencing (personal communication of Rebouissou S.).
Removed from DepMap;
Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: Amelogenin: X->X,Y
Contaminated. Shown to be a LN-444 derivative (PubMed=22570425). Originally thought to originate from a 66 year old male patient with a glioblastoma.
TP53 mutation indicated incorrectly as being at p.Ile251Leu (c.751A>C) in PubMed=15900046
Misclassified. Originally thought to be a hepatocellular carcinoma cell line but shown to be from an hepatoblastoma (PubMed=19751877).
Indicated to have a TP53 p.Glu285Lys (c.853G>A) mutation according to PubMed=1311061
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: deletion of D18S51: 14
NRAS mutation indicated to be at p.Gly12Asp (c.35G>A) in PubMed=9379676
TP53 mutation indicated as c.750_751insC in PubMed=8575860
TP53 mutation indicated incorrectly as being at c.637C>T in PubMed=2052620
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D18S51: 11,14->14,15
Misclassified. Grand-parent cell line (GM01500) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
Removed from DepMap; Removed from DepMap;
NCI-H358 and NCI-H358M (CVCL_JA53) could be identical
Contaminated. Parent cell line (MDA-MB-435) has been shown to be a M14 derivative.
Probably misidentified/contaminated. Except of a loss of an allele of TH01 the STR profile of SF172 is identical to that of SF763. Furthermore we could not find in the literature any trace of the exact origin of SF172 and, according to a personal communication of Shai A. from the UCSF Biorepository, there is no record of SF172 in their system while SF763 is registered there. The TP53 mutation recorded for SF763 is also identical to the one in SF172.
TP53 mutations indicated to be at p.Met237Arg (c.710T>G) and p.Gly244Cys (c.730G>T) (PubMed=2144611)
Contaminated. NCI-H157 and NCI-H1264 have been shown to be identical.
The exact relationship between HMCB (CVCL_3317) and RPMI-7262/7272/7932/7962/7972 is not clear: all are derived from patient 'Bowes' melanoma
Indicated to have an additional TP53 p.Arg248Trp (c.742C>T) mutation according to PubMed=2052620, but not confirmed by other references or by CCLE and Cosmic-CLP
Partially contaminated. The ICLC stock (now discontinued) was found to be contaminated, probably by U-251MG (CVCL_0021).
Could be identical to HTK- (CVCL_2522)
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: CSF1PO: 11,12->12, D18S51: 10->10,13, D5S818: 11,12->12, D7S820: 9,10->10 and FGA: 21->21,25
Contaminated. Shown to be a SW579 derivative (PubMed=25877200; DSMZ). Originally thought to originate from a thyroid gland follicular carcinoma metastasizing to the sternum of a 70 year old Chinese female patient.
Contaminated. Shown to be a COLO 800 derivative (PubMed=10508494; PubMed=20143388).
Contaminated. Shown to be a PSN1 derivative (PubMed=25877200). Originally thought to originate from the chest of a 36 year old male melanoma patient with skin metastases.
Removed from DepMap;
TP53 mutation indicated incorrectly as being at c.747G>T in PubMed=8389256
Could be identical to 143B (CVCL_2270)
Contaminated. Shown to be a PANC-1 derivative.
Was incorrectly stated to have deleterious mutations in ATM in PubMed=12105990
Possibly contaminated. May be identical to OC 314 (CVCL_1616) according to STR profiling done at ICLC and to MSI data (PubMed=15677628).
Possibly misclassified. Originally thought to be a high grade ovarian serous adenocarcinoma but suspected to have a upper gastrointestinal origin (PubMed=27353327).
Misclassified. Originally thought to be a Hodgkin lymphoma cell line but is a B-lymphoblastoid cell line (PubMed=12592342; PubMed=20143388; PubMed=29533902).
Partially contaminated. Some laboratories that are redistributing this cell line are in fact redistributing a contaminated cell line of mouse origin (PubMed=25182563).
Removed from DepMap; Removed from DepMap;
Misclassified. Originally thought to be a Wilm's tumor cell line but shown to be from an Ewing sarcoma (PubMed=17154184).
Contaminated. Shown to be a U-251MG derivative (PubMed=18304946; PubMed=20143388; PubMed=22570425). Originally thought to originate from a 47 year old patient with a left parieto-occipital glioblastoma.
Contaminated. Shown to be a ZR-75-1 derivative (PubMed=23136038). Originally thought to originate from a 55 year old woman patient with a breast carcinoma.
Stated to originate from a patient with a biphasic synovial sarcoma, however does not contain the SST-SSX1/SSX2 translocation which is typical of synovial sarcoma
Often called PLC8024 in Chinese literature probably because of a concatenation between PLC/PRF/5 and ATCC-8024
TP53 mutation indicated to be at p.Asn239Asp (c.715A>G) in DOI=10.11418/jtca1981.16.3_173 and PubMed=9359923
Partially misidentified. For a period of time Asterand (now BioIVT) mistakenly distributed SUM149PT (CVCL_3422) under the designation of SUM229PE. This leads to the publication of a STR profile (PubMed=25877200) which was almost identical to that of SUM149PT.
Misclassified. Although established from a surgical specimen from a cystadenocarcinoma of the ovary in a 46 year old female Caucasian, it now seems likely that it was established from an ovarian metastasis of a colonic carcinoma (PubMed=10433623).
PubMed=27270441 reports a STR profile (CSF1PO: 10; D13S317: 11; D16S539: 9,11; D5S818: 13; D7S820: 8,10; TH01: 7; TPOX: 8; vWA: 17,19) which is completely different from that of DepMap and ECACC
Possibly misidentified. It is not certain that this cell line originate from a hairy cell leukemia (PubMed=22653958).
Indicated to be from a 58 year old female patient in ATCC and from a 53 year old in Sloan Kettering tech transfer site
Established from the trophoblastic tumor of the placenta of a 24 year old woman, but the cell line is from the male fetus
A TP53 mutation is indicated as being at p.Gln167His (c.501G>T) in PubMed=7819056 but has not been confirmed by CCLE and Cosmic-CLP
Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
Removed from DepMap;
Possibly misclassified. It is not certain that this cell line originate from a metastatic melanoma. Lacks the expression of three protein markers: S100, HMB-45 and Melan-A commonly found in melanoma cell lines (PubMed=27087056). Has a CTNNB1 mutation not seen in other melanoma cell lines (PubMed=11930117).
Misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin.
Indicated as originating from a female patient in ATCC and from a male patient in PubMed=2985257 and PubMed=2986243
Was originally classified as originating from a histiocytic lymphoma
TP53 mutation indicated incorrectly as being at p.Arg175His (c.524G>A) in PubMed=7665247
Was originally classified as originating from a follicular lymphoma
Probably misidentified. Originally thought to be a acute monoblastic leukemia but seems to be a T-ALL cell line (PubMed=15843827). Was also said to originate from a 40 year old female patient (PubMed=6593267) but has a male STR profile.
Previously erroneously indicated as originating from a male patient, correct sex assignment from Moore G.E. in a personal communication to the authors of PubMed=9892114
Contaminated. Shown to be a ETK-1 derivative (RCB). Originally thought to originate from a 64 year old female patient with an intrahepatic cholangiocarcinoma.
Partially contaminated. Some stocks of Ca9-22 are contaminated with MSK-922 (PubMed=21868764).
Contaminated. Shown to be a RERF-LC-A1 derivative (PubMed=16643607; PubMed=20143388).
Contaminated. Shown to be a NCI-H125 derivative. Originally thought to originate with the pleural effusion of a mesothelioma in a 64 year old male patient. Removed from DepMap;
Contaminated. Shown to be a GLAG-66 derivative (STR profile and somatic mutations from Cosmic-CLP).
Indicated to have a EGFR p.Leu858Arg (c.2573T>G) mutation according to PubMed=16105816) but this is in contradiction of results of exome sequencing in CCLE and Cosmic-CLP
Misclassified. Parent cell line (SK-N-MC) was originally thought to be a neuroblastoma cell line but shown to be from an Askin tumor.
Contaminated. Shown to be a MKN74 derivative (PubMed=20143388).
Contaminated. NCI-H1304 and NCI-H1870 have been shown to be identical.
We are not certain that NCI-H322 and NCI-H322M are identical
Contaminated. Shown to be a OVSAYO derivative (PubMed=20143388). Originally thought to originate from a 46 year old female patient with an ovarian adenocarcinoma.
Misclassified. Originally thought to be a rhabdomyosarcoma cell line but shown to be from an Ewing sarcoma (PubMed=17154184).
Possibly misidentified/contaminated. Shown to be identical to SBC-2 (JCRB web site and STR profile).
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D13S317: 12->11,12
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D18S51: 20->14,15 and FGA: 19->19,24
Contaminated. Parent cell line (YMB-1) has been shown to be a ZR-75-1 derivative (PubMed=23136038).
Misclassified. Originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line (PubMed=7579375; PubMed=10516762).
Contaminated. Shown to be a Peer derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from a 11 year old patient with T-ALL.
Probably misidentified. Originally thought to be a acute monoblastic leukemia but seems to be a T-ALL cell line (PubMed=15843827). Was also said to originate from a 40 year old female patient (PubMed=6593267) but has a male STR profile.
Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
Partially contaminated. Some stocks (such as IFO50028) were contaminated by Daudi.
Was incorrectly reported to be a SSP-25 contaminated cell line by Riken and thus also by ICLAC but it was later found out that SSP-25 was in fact contaminated by ETK-1 and not the other way around
Possibly misclassified. It is not certain that this cell line originate from a hairy cell leukemia (PubMed=22653958).
Misclassified. Originally thought to be a Hodgkin lymphoma cell line but is a B-lymphoblastoid cell line (PubMed=12592342; PubMed=29533902).
Misclassified. Originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line (PubMed=10516762).
Indicated to be from a 67 year old male patient in CelloPub=CLPUB00151 and from a 72 year old in JCRB IFO50435
Removed from DepMap;
Misclassified. Originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line (PubMed=10516762).
This cell line is exclusively owned and controlled by NantKwest, Inc. NantKwest and its affiliate, Brink Biologics, Inc. are the sole authorized distributors for both commercial and non-commercial research requestors. There are no other authorized commercial and non-commercial suppliers of NK-92MI. Contact NantKwest and Brink Biologics for information concerning current inventory and cell line use and support
Misclassified. From a B-cell lymphoma and not from a gastric cancer (PubMed=12226758).
Contaminated. Shown to be a Marcus derivative (PubMed=20143388).
Contaminated. TE-2, TE-3, TE-7, TE-12 and TE-13 have been shown to be identical (PubMed=17804709; PubMed=20143388).
Contaminated. Shown to be a A-549 derivative (PubMed=21868764). Originally thought to originate from a base of tongue squamous cell carcinoma.
TP53 mutation indicated incorrectly as being at c.701A>G in PubMed=9290701