Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: SS2_R00010_Clinical Informatics_2023_05_02  


We are seeking a dynamic and innovative leader to join our team as a leader in clinical bioinformatics and cancer precision genomics. In this role, you will oversee the development and execution of cancer genome analysis with a focus on precision medicine approaches and reporting. You will lead a team of bioinformatic analysts and work closely with other teams at the Genome Sciences Centre to ensure that projects and analyses are executed on time, within budget, and to the highest standards.  The role is part of the Genome Sciences Centre’s precision medicine initiative the “Personalized Oncogenomics Program” (POG) and the Terry Fox Research Institute’s “Marathon of Hope”.


  • Leadership, support and day-to-day supervision of members of the clinical informatics team
  • Lead and manage a team of researchers in the design, execution, and analysis of cancer precision genomics analysis and reporting.
  • Develop and implement strategies to optimize and improve cancer genomics research approaches and methodologies.
  • Collaborate with leadership teams from cancer genomic studies, including the Personalized OncoGenomics Program (POG) and Precision Oncology For Young People (PROFYLE), to deliver genomics information in the area of precision oncology. This will include:
    • Delivery of whole genome and transcriptome integrative analysis genomic reports to multi-disciplinary clinical teams
    • Collaboration with stakeholders and research groups to deliver novel technologies in the context of precision oncology studies
    • Providing leadership and expertise to support program-wide decision-making and strategic planning
    • Collaborate with stakeholders to provide leadership and technical expertise for scientific publications and grant writing
  • Engage with national and international collaborative genomics initiatives including large-scale genomics projects and investigator initiated clinical trials. This will include:
    • Participation in the development of clinical trial design
    • Collaborate with members of external organizations for the development of distributable software
    • Establishment and implementation of data and software sharing approaches
  • Conduct bioinformatic analyses and interpretation of genomic data
  • Collaborate with bioinformatics teams across the organization to help develop and improve production bioinformatics pipelines and genomics reporting in a clinical research setting.
  • Collaborate with teams at the Genome Sciences Centre including those representing bioinformatics, computational biology, and data science to ensure the delivery of high-quality reports and results.
  • Engage with external collaborators to identify new opportunities and foster relationships to support ongoing research efforts.
  • Participate in the preparation and submission of grant proposals to fund cancer genomics research initiatives.
  • Retain familiarity with the latest advances in cancer genomics research and emerging technologies and apply this knowledge to inform new research and development strategies.


  • PhD in Genetics, Genomics, Cancer Biology, or related field.
  • 5+ years of experience in cancer genomics research, with a focus on precision medicine.
  • Demonstration of leadership and management skills, with experience leading cross-functional teams.
  • Familiarity with genomic data analysis approaches and data interpretation.
  • Excellent communication and interpersonal skills, with the ability to work collaboratively with internal and external stakeholders.
  • A strong publication record in the field of genomics.

Required skills:

  • Highly collaborative and team-oriented approach is required.
  • Effective oral and written communication skills
  • In-depth knowledge and extensive research experience in the field of cancer biology and cancer genomics
  • Proficiency in one or more common programming and/or scripting language
  • Ability to manage time and engagement across diverse tasks and projects effectively while meeting expected deliverables in the allocated time-frame


Please submit a detailed cover letter and resume to, using SS2_R00010_Clinical Informatics_2023_05_02  in the subject line of your email.

This posting will remain online until filled.


As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

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