Job Reference No. RP_R00008_Karsan Lab_2022_05_31

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. Dr. Aly Karsan and the Karsan Lab team are seeking a Research Programmer to join a Marathon of Hope Cancer Centre research project.  

The successful applicant will be working with other research programmers in the Karsan lab to develop data analysis pipelines for various next-generation sequencing (NGS) data such as—but not limited to—scRNA-Seq, targeted sequencing, ATAC-Seq, and BS-Seq. We seek candidates with strong analytical and programming skills to research, develop, and improve our research pipelines for studying cancer evolution. The role is ideally suited to detail-oriented individuals with a strong interest in data analysis, research, and scientific programming within a high throughput academic setting. 

By working within the Karasn Lab at the GSC, you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada. The Karsan lab has a history of strong publications and a diverse computational biology core for knowledge sharing, collaboration, and support. 

This is a non-union position funded by a BC Cancer Foundation Grant. We offer a competitive salary, excellent benefits and significant career development opportunities.  

Responsibilities 

  • Design and implement bioinformatic data pipelines to meet objectives of the project.
  • Work with other project team members to develop and test code and implement analysis.
  • Evaluate and incorporate third-party software into pipelines.
  • Produce thorough but concise written documentation of experiments, algorithms, validations and other procedures as required.

Qualifications

  • Graduation from a recognized Bachelor of Science Program in Computer Science or relevant program. A Master’s degree in a relevant field would be a strong asset. 
  • Two (2) years of recent related experience or an equivalent combination of education, training and experience.

Core Skills and Abilities: 

  • Expertise with scientific programming and ablility to provide links to code samples via GitHub.
  • Familiarity with molecular and cellular biology.
  • Excellent verbal and written communication skills.
  • Demonstrated ability to interpret results.
  • Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools.
  • Established ability to efficiently organize work assignments and establish priorities.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets:

  • Familiarity in statistical analysis using modern computational tools (experience with any relevant tools will be considered, but R and Python are preferred).
  • Familiarity in next-generation sequencing datasets.
  • Understanding of cancer biology.
  • Functional knowledge of distributed version control systems, such as SVN or GIT.

How to Apply

Applicants should submit: a CV; a one-page cover letter highlighting relevant research experience, interests and goals; and the names and contact details of three (3) references.

Please send your application to bcgscjobs@bcgsc.ca and include the job reference number in the subject line of the email. While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

We believe that equity and diversity are essential for the advancement of human knowledge and science.  We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

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