Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.


Job Reference Number: PDF_01553_Steif Lab_2023_02_23

This is an opportunity to advance single cell omics technology and work alongside highly motivated colleagues in a We are looking for an outstanding Postdoctoral Fellow with experience developing and applying computational methods for high-throughput omics analysis to join Dr. Adi Steif’s computational cancer genomics research group in Vancouver, Canada.

The successful applicant will be part of an exceptional multidisciplinary team of engineers, molecular biologists and bioinformatic scientists developing a new instrument for single cell omics profiling. Funded by a Genome BC Pilot Innovation Fund grant, the project is a close collaboration with the groups of Dr. Marco Marra (Medical Genetics) and Dr. Karen Cheung (Biomedical Engineering) at the University of British Columbia. The candidate will have the opportunity to work with unique and complex single cell imaging, DNA and RNA sequencing datasets, profiling tumour heterogeneity and evolution.

By joining the Steif Lab, you will develop close relationships with world-renown specialists in genomics and bioinformatics and have access to robust high performance computing and next generation sequencing facilities, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities.


Working in a multidisciplinary team, the postdoctoral fellow will develop and apply computational tools and analytical workflows for single cell omics analysis. This is a one-year term appointment, with potential for renewal. Responsibilities include:

  • Regularly review the scientific literature
  • Contribute to experimental design and planning
  • Data preprocessing and quality control
  • Data analysis, visualization, and biological interpretation
  • Develop and maintain well-documented code
  • Regularly update Dr. Steif and key collaborators on the status of projects
  • Participate in and present research updates at lab meetings, team meetings and conferences
  • Contribute to scientific writing, including the preparation of research manuscripts and grant applications
  • May be involved in recruitment, management, and supervision of trainees


  • A PhD in bioinformatics, computer science, statistics or related discipline
  • At least 2 years of research experience in bioinformatics, with a record of first-author publication
  • Experience in genomics and high-throughput sequencing data analysis
  • Experience in cancer research is an asset
  • Programming fluency in Python or R
  • Experience working in a Unix/Linux computing environment
  • Critical thinking and attention to detail
  • Excellent verbal, written and interpersonal communication skills
  • Ability to work independently and in a collaborative interdisciplinary team
  • A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines


Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of three references to, using Job Reference No: PDF_01553_Steif Lab_2023_02_23 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.


As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

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