The Healthy Aging Study (the Super-Seniors Study)
We study genetic factors that underlie healthy aging and resistance to age-related diseases such as cancer, cardiovascular and pulmonary disease, dementia and diabetes.
|Project Leaders||Angela Brooks-Wilson|
|Project Co-Investigators||Joseph Connors , Denise Daley|
For all project related inquires contact:Diane Salema
Genome Sciences Centre
BC Cancer Research Centre
BC Cancer Agency
Simon Fraser University
University of British Columbia
|Project Resources and Information|
The practical goals addressed by this study of healthy aging are not necessarily to increase human longevity beyond the current normal life span, but rather to ensure that individuals live to the upper end of that life span in good health with a good quality of life. Fewer than half of Canadians are fortunate to live to the age of 85, and only a minority of these achieve this age free of major age-related diseases such as cancer, cardiovascular disease, pulmonary disease, diabetes or Alzheimer's and maintain a good quality of life. Although environmental factors are also important, people who reach this age in good health may represent a group who either lack susceptibility factors that contribute to disease in the general population or may possess resistance factors that enhance their ability to resist disease and prolong lifespan.
To Participate in this Study
The BC Cancer Agency is recruiting volunteers to participate in a study of Healthy Aging. The goal of this study is to identify inherited genetic factors associated with healthy aging and resistance to age-related diseases.
We are looking for people who:
- Are 85 years of age or older. And
- Have never been diagnosed with a major health concern, such as:
- Cardiovascular or heart disease
- MI (myocardial infarction) or heart attack
- Stroke or TIA (ischemic attack)
- Peripheral vascular disease
- Lung Disease or emphysema
- Diabetes mellitus
We also welcome any people who are 100 years old, or older.
Participation in the study consists of:
- Answering questions regarding health and family history by questionnaire.
- Providing a saliva or small blood sample (approximately 2 - 3 tablespoons).
- Providing contact information for other eligible relatives.
If you or someone you know meet the above criteria and would like to learn more about the Healthy Aging Study, please contact the Research Coordinator, Diane Salema.
All information obtained in this study will be kept strictly confidential.
Tindale LC, Zeng A, Bretherick KL, Leach S, Thiessen N, Brooks-Wilson AR. Burden of Common Complex Disease Variants in the Exomes of Two Healthy Centenarian Brothers. Gerontology. 2015;62(1):58-62.
Tindale LC, Leach S, Ushey K, Daley D, Brooks-Wilson AR. Rare and common variants in the Apolipoprotein E gene in healthy oldest old. Neurobiol Aging. 2014 Mar;35(3):727.
To donate to support the Super-Seniors Study, please contact Stephanie for assistance:
Stephanie McInnis, Project Manager
Genome Sciences Centre, BC Cancer Agency
Phone: 604-675-8000 x 7965