Bioinformatics of Mammalian Gene Expression
This project proposes to find the DNA elements that control gene expression with computational biology and gene expression profiling.
|Project Leaders||Steven Jones , Marco Marra|
|Project Resources and Information|
The various cell types in our bodies are dependent on the correct amount of gene expression in the proper place at the right time. This project proposes to find the DNA elements that control gene expression with computational biology and gene expression profiling. The scientists at the Genome Science Centre will compare genome DNA sequences across species and expression data across different platforms to identify regulatory elements. This project will determine and record the expression of all mouse and many human genes, the most comprehensive effort in mammals to date. This will lead to an understanding of the complex networks of gene regulation that play a role in the normal development of mice and humans. The ability to predict key regulatory events and gene expression controls will facilitate the development of innovative diagnostic tools and gene-based therapies for many disease states.
Contact InformationFor all project related inquires please contact us.
Cynthia Ferguson, Project Manager
Genome Sciences Centre, BC Cancer Agency
Phone: 604-707-5900 x 6081