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Last modified 2009-11-20 10:23

As the largest capacity genomics centre of its type in Canada, the GSC specializes in high-throughput, large-scale genome research activities encompasing cancer genetics, bioinformatics, LIMS, DNA sequencing, data analysis, genome mapping, gene expression profiling, proteomics and technology development.

The facility was designed specifically for flexibility and high throughput with a particular emphasis on efficiency and rapid scale-up. Research is carried out on the latest instrumentation, with data collected and analyzed on one of the most innovative and flexible bioinformatics computing facilities in the world.

The GSC has the following services available:

Sequencing

  • Second generation sequencing - Illumina GAiix and AB SOLiD
    • Whole genome sequencing
    • Whole transcriptome shotgun sequencing (RNA-Seq)
    • Micro RNA
    • Gene Expression (SAGE)
    • ChIP
    • Coming soon: exome capture; indexed sequencing
  • High-throughput DNA sequencing - AB 3730XL
    • ESTs
    • Whole genome shotgun sequencing (viruses, bacteria, fungi)
    • BAC end sequencing
    • Full-length cDNA sequencing
    • Amplicon sequencing

 

Affymetrix

  • Analysis of Affymetrix microarray data (CNV, SNP, Expression, Alternative Splicing)

    Bioinformatics Platform Services

    • Genome Annotation
    • High-throughput PCR primer prediction
    • Regulatory element prediction
    • Laboratory information management systems (LIMS)
    • Data dissemination (e.g. web/ftp sites, submission to official repositories)
    • Development and maintenance of biological databases
    • Other Custom Services

    Proteomics

    • Protein-protein interaction mapping
    • Phospho-peptide/phospho-protein analysis
    • Protein isoform detection and quantification
    • Protein indentification and quantification

     

    In-silico drug design

    • Molsoft ICM software for molecular docking
    • 400 CPU compute cluster to screen 1+ million compounds per day

     

    Contact Information

    For additional information or to arrange for a cost quotation, please contact us.

    Diane Miller, Project Manager
    Genome Sciences Centre, BC Cancer Agency
    Suite 100, 570 West 7th Ave
    Vancouver, BC, V5Z 4S6
    Email: dmiller@bcgsc.ca
    Phone: (604) 707-5808
    Fax: (604) 877-6085