KLEAT

c(K)LEavage site Analysis of Transcriptomes (KLEAT) identifies 3' UTR ends of transcripts in de novo RNA-Seq assemblies.

Project Description

KLEAT is a post-processing tool for cleavage site analysis of transcriptomes. In eukaryotic cells, alternative cleavage of 3’ UTRs can affect transcript stability, transport and translation. For polyadenylated transcripts, cleavage sites can be characterized with short-read sequencing using specialized library construction methods. However, for large-scale cohort studies as well as for clinical sequencing applications, it is desirable to characterize such events using RNA-seq data, as RNA-seq is already widely applied to identify other relevant information on the investigated transcriptomes. CLEAT addresses this need.

Current Release
KLEAT 2.0

Released Apr 28, 2015

CLEAT has changed its name to KLEAT. In version 2.0, KLEAT is no longer dependent on the Trans-ABySS analysis framework. Instead, a standalone script is provided to run the assembly and alignments. In addition, the input formats to KLEAT have also been modified to adopt the more standard formats of BAM for alignments and GTF for annotation.
More about this release…

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KLEAT 2.0

All Releases

Version Released Description Compatibility Licenses Status
2.0 Apr 28, 2015 CLEAT has changed its name to KLEAT. In version 2.0, KLEAT is no longer dependent on the Trans-ABySS analysis framework. Instead, a standalone script is provided to run the assembly and alignments. In addition, the input formats to KLEAT have also been modified to adopt the more standard formats of BAM for alignments and GTF for annotation. More about this release… BCCA (academic use) final
1.0 Mar 28, 2014 Initial release of CLEAT More about this release… BCCA (academic use) final
Project Resources

Project owner: traymond