Alternative expression analysis of Pre- and Post- treatment MultipleMyeloma tumours
Library statistics (link to library summary):
HS0621 (PreTx_Un)
HS1010 (PostTx_Un)
HS0622 (PreTx_En)
HS0623 (PostTx_En)
Summary of expressed, differentially expressed and alternatively expressed features
Welcome to the ALEXA-Seq data viewer. This viewer allows you to examine the expression, differential expression and alternative expression for several feature types (exons, junctions, introns, etc.) for all EnsEMBL loci. The following table provides links to lists of: the most highly abundant expressed (EXP) features, all significant differentially expressed (DE) features and all significant alternatively expressed (AE) features. Click on an icon to view these lists for the desired feature type. The number of features is enumerated beneath each icon. Note that for EXP tables, only the top 1% of expressed features will be summarized. Example 1: to see the most highly expressed exons in each library, click the 'EXP' icon in the 'ExonRegion' row of the table. Example 2: to view a ranked list of significant differentially expressed transcripts, click the 'DE' icon in the 'Transcript row of the table. Example 3: to view a ranked list of alternatively expressed, novel exon-exon junctions click the 'AE' icon in the 'NovelJunction' row of the table. For a detailed description of the feature types and how the ALEXA-Seq data viewer works, refer to our manuscript. To view data for a specific gene, use the 'SEARCH' link above.
| Data Type | Expression (All libraries) | Differential Expression (All comparisons) | Alternative Expression (PostTx_vs_PreTx_Un) | Alternative Expression (PostTx_vs_PreTx_En) | Alternative Expression (En_vs_Un_PreTx) | Alternative Expression (En_vs_Un_PostTx) |
| Gene |  (14,023) |  (4,710) | N/A | N/A | N/A | N/A |
| Transcript | (14,332) | (3,830) |  (341) | (264) | (326) | (484) |
| ExonRegion | (152,380) | (57,932) | (4,443) | (3,922) | (7,088) | (5,571) |
| Junction | (119,597) | (30,133) | (4,405) | (5,746) | (6,537) | (8,983) |
| KnownJunction | (117,137) | (29,991) | (4,351) | (5,642) | (6,498) | (8,792) |
| NovelJunction | (2,460) | (150) | (77) | (109) | (42) | (165) |
| Boundary | (33,898) | (7,112) | (2,161) | (2,649) | (1,824) | (3,168) |
| KnownBoundary | (9,518) | (4,238) | (1,008) | (773) | (694) | (1,168) |
| NovelBoundary | (24,380) | (4,023) | (1,727) | (2,607) | (621) | (1,659) |
| Intron | (9,684) | (875) | (199) | (303) | (222) | (228) |
| ActiveIntronRegion | (20,887) | (5,738) | (3,178) | (5,179) | (779) | (1,107) |
| SilentIntronRegion | (11,123) | (712) | (243) | (475) | (294) | (484) |
| Intergenic | (1,231) | (117) | N/A | N/A | N/A | N/A |
| ActiveIntergenicRegion | (11,072) | (3,421) | N/A | N/A | N/A | N/A |
| SilentIntergenicRegion | (4,500) | (393) | N/A | N/A | N/A | N/A |