Alternative expression values of the type: ExonRegion for comparison: HeartE12_vs_HeartE11 (abs(SI) value > 2)


Distribution of log2 SI values for comparison: HeartE12_vs_HeartE11 and data type: ExonRegion

Distribution of all splicing index values that meet the SI cutoff (indicated by red dotted lines) for the feature type: ExonRegion. The total number of features with SI values exceeding the cutoff, as well as the max and min log2 SI observed are noted in the legend. *If you can not see the figure below, click here




Significant alternatively expressed ExonRegion features

The following table provides a ranked list of alternatively expressed ExonRegion features for a single pair-wise library comparison. The first column contains the Gene Name (which links to the ALEXA-Seq gene record), the Feature Name, and the name of each library being compared (which links to the feature's coordinates in the UCSC Genome Browser and displays expression data). The 'SI' column reports the Splicing Index calculated for the feature. The 'Gene FC' column reports the Fold-Change calculated for the entire gene to which the feature belongs. The 'Seq FC' column reports the Fold-Change of the feature itself. The 'Reciprocity' column reports the Reciprocity Index (RI) for the feature. The 'Percent Seq DE' column reports the Percent Feature Contribution (PFC) value for the feature. A description of the purpose and calculation of SI, RI and PFC values can be found in our manuscript. Briefly, the SI value is a measure of the degree of change in expression of a feature (e.g. an exon) between two conditions relative to the change in expression at the gene level. The RI value is a measure of the degree to which the change of the feature is reciprocal in direction to that observed for the gene overall. For example, if an exon is up-regulated but the gene overall is down-regulated, this will give a higher RI value. The PFC value is a measure of the degree of differential expression of the feature compared to the entire gene. For example, if a gene is not changed overall between two conditions, but the feature is highly differentially expressed, this will give a higher PFC value. To sort this table by each of the data values, simply click the column header. A bold row indicates that the feature is not currently supported by EST or mRNA sequence alignments. For exon junction features the number of exons skipped by the junction is indicated as 'Sn' where n is the number of exons skipped (e.g. S0 means no exons skipped, S1 means one exon skipped, etc.).


RANKHeartE12_vs_HeartE11 (Gene | Feature | Links)SIGene FCSeq FCReciprocity
(RI)
Percent Seq DE
(PFC)
q-value
1 Med12l | ER46a | (HeartE12) | (HeartE11)1.35-1.262.03-1.9875.29N/A
2 Gtpbp10 | ER1b | (HeartE12) | (HeartE11)1.32-1.232.03-1.8277.42N/A
3 Rpl13 | ER4a | (HeartE12) | (HeartE11)-1.531.27-2.29-1.8077.84N/A
4 Pgk1 | ER2a | (HeartE12) | (HeartE11)1.89-1.302.85-1.6879.80N/A
5 Rpl7a | ER5a | (HeartE12) | (HeartE11)-1.421.21-2.22-1.6380.67N/A
6 Gm962 | ER1a | (HeartE12) | (HeartE11)-2.211.31-3.53-1.5482.44N/A
7 Mtap7d3 | ER1a | (HeartE12) | (HeartE11)1.78-1.222.82-1.4883.89N/A
8 Nmi | ER1b | (HeartE12) | (HeartE11)-1.341.14-2.21-1.4185.44N/A
9 Lnx1 | ER7b | (HeartE12) | (HeartE11)1.80-1.192.93-1.3886.18N/A
10 Bbx | ER1c | (HeartE12) | (HeartE11)1.29-1.122.17-1.3586.94N/A
11 Ptp4a1 | ER1b | (HeartE12) | (HeartE11)1.16-1.112.01-1.3586.97N/A
12 2310001H12Rik | ER7b | (HeartE12) | (HeartE11)1.30-1.122.20-1.3287.85N/A
13 1110005A23Rik | ER7a | (HeartE12) | (HeartE11)2.30-1.214.07-1.3287.99N/A
14 Foxn2 | ER1a | (HeartE12) | (HeartE11)1.67-1.152.77-1.3188.09N/A
15 Ptp4a1 | ER2a | (HeartE12) | (HeartE11)1.30-1.112.22-1.3088.36N/A
16 Cdk8 | ER1a | (HeartE12) | (HeartE11)1.57-1.132.63-1.2988.86N/A
17 Ddx46 | ER2a | (HeartE12) | (HeartE11)1.37-1.112.33-1.2889.04N/A
18 Ccdc46 | ER1a | (HeartE12) | (HeartE11)1.25-1.102.16-1.2889.14N/A
19 Upp1 | ER1b | (HeartE12) | (HeartE11)1.34-1.102.29-1.2789.42N/A
20 Gale | ER1a | (HeartE12) | (HeartE11)1.13-1.082.02-1.2689.75N/A
21 Hemk1 | ER1a | (HeartE12) | (HeartE11)1.87-1.143.20-1.2689.75N/A
22 Zfp800 | ER3b | (HeartE12) | (HeartE11)1.49-1.112.54-1.2590.13N/A
23 Ubb | ER1a | (HeartE12) | (HeartE11)-1.141.08-2.04-1.2390.52N/A
24 Rint1 | ER1b | (HeartE12) | (HeartE11)1.18-1.072.11-1.2191.25N/A
25 Adal | ER1b | (HeartE12) | (HeartE11)1.34-1.082.34-1.2191.30N/A
26 Btaf1 | ER1a | (HeartE12) | (HeartE11)1.09-1.062.01-1.1992.10N/A
27 Gimap8 | ER4a | (HeartE12) | (HeartE11)1.18-1.072.12-1.1892.22N/A
28 Ankrd29 | ER1a | (HeartE12) | (HeartE11)1.36-1.072.38-1.1892.48N/A
29 Prr8 | ER1c | (HeartE12) | (HeartE11)1.16-1.062.11-1.1693.05N/A
30 Adal | ER1c | (HeartE12) | (HeartE11)1.77-1.083.14-1.1593.41N/A
31 Ttll5 | ER1b | (HeartE12) | (HeartE11)1.63-1.082.87-1.1593.45N/A
32 Ttll5 | ER1a | (HeartE12) | (HeartE11)1.63-1.082.88-1.1593.46N/A
33 Isca1 | ER2a | (HeartE12) | (HeartE11)1.24-1.062.23-1.1593.51N/A
34 Tcf7l2 | ER1d | (HeartE12) | (HeartE11)1.09-1.052.03-1.1593.66N/A
35 Naca | ER4a | (HeartE12) | (HeartE11)1.17-1.042.15-1.1294.68N/A
36 Brwd1 | ER2a | (HeartE12) | (HeartE11)1.37-1.042.47-1.1095.43N/A
37 Clec16a | ER6a | (HeartE12) | (HeartE11)-1.181.04-2.18-1.1095.58N/A
38 Aph1a | ER6c | (HeartE12) | (HeartE11)-1.761.05-3.23-1.0896.20N/A
39 Brwd1 | ER1c | (HeartE12) | (HeartE11)1.80-1.043.33-1.0796.53N/A
40 Fbxl10 | ER26c | (HeartE12) | (HeartE11)-1.531.04-2.78-1.0796.63N/A
41 Brwd1 | ER1a | (HeartE12) | (HeartE11)1.92-1.043.62-1.0796.74N/A
42 Clint1 | ER1a | (HeartE12) | (HeartE11)1.53-1.032.80-1.0696.97N/A
43 Fam114a2 | ER1b | (HeartE12) | (HeartE11)1.14-1.022.15-1.0696.98N/A
44 Brwd1 | ER1b | (HeartE12) | (HeartE11)2.14-1.044.23-1.0697.08N/A
45 4933404M19Rik | ER5c | (HeartE12) | (HeartE11)-1.161.02-2.19-1.0697.22N/A
46 Ttc19 | ER1b | (HeartE12) | (HeartE11)1.74-1.033.24-1.0597.45N/A
47 Parp9 | ER3a | (HeartE12) | (HeartE11)1.35-1.022.49-1.0597.82N/A
48 5033430I15Rik | ER1a | (HeartE12) | (HeartE11)1.50-1.022.77-1.0498.15N/A
49 Whdc1 | ER1c | (HeartE12) | (HeartE11)2.12-1.034.24-1.0498.29N/A
50 Ptpra | ER1a | (HeartE12) | (HeartE11)1.32-1.012.47-1.0299.26N/A
51 Trim34 | ER16a | (HeartE12) | (HeartE11)-1.771.00-3.40-1.0099.90N/A
52 Asxl3 | ER2a | (HeartE12) | (HeartE11)1.291.012.48N/A98.49N/A
53 Tnfrsf22 | ER6a | (HeartE12) | (HeartE11)1.891.204.44N/A89.25N/A
54 Adam8 | ER4a | (HeartE12) | (HeartE11)-2.04-1.03-4.23N/A97.97N/A
55 Sgcb | ER1a | (HeartE12) | (HeartE11)1.011.122.27N/A87.63N/A
56 Gkap1 | ER9a | (HeartE12) | (HeartE11)-1.06-1.07-2.24N/A91.83N/A
57 Grpel1 | ER1a | (HeartE12) | (HeartE11)1.061.032.14N/A96.37N/A
58 Katnal2 | ER4a | (HeartE12) | (HeartE11)-1.17-1.16-2.61N/A86.87N/A
59 Nmnat2 | ER8a | (HeartE12) | (HeartE11)1.021.402.83N/A75.77N/A
60 Pfkfb4 | ER4a | (HeartE12) | (HeartE11)1.041.182.44N/A84.18N/A
61 Nmnat3 | ER1b | (HeartE12) | (HeartE11)1.191.132.57N/A88.60N/A
62 Alkbh2 | ER1b | (HeartE12) | (HeartE11)1.121.082.35N/A91.99N/A
63 Gyk | ER10a | (HeartE12) | (HeartE11)-1.23-1.19-2.79N/A85.48N/A
64 Thap7 | ER1a | (HeartE12) | (HeartE11)1.121.182.56N/A84.97N/A
65 Neil1 | ER2a | (HeartE12) | (HeartE11)1.051.282.65N/A79.78N/A
66 Igfbp7 | ER1a | (HeartE12) | (HeartE11)1.031.072.20N/A91.73N/A
67 Pfkfb2 | ER1a | (HeartE12) | (HeartE11)1.051.022.10N/A97.90N/A
68 BC057079 | ER46b | (HeartE12) | (HeartE11)-1.51-1.23-3.51N/A85.84N/A
69 Nkd2 | ER1a | (HeartE12) | (HeartE11)1.011.352.72N/A77.12N/A
70 Ccbl2 | ER2b | (HeartE12) | (HeartE11)-1.19-1.22-2.78N/A83.96N/A
71 Zmynd15 | ER2a | (HeartE12) | (HeartE11)1.131.222.68N/A83.09N/A
72 Idi1 | ER3a | (HeartE12) | (HeartE11)-1.26-1.42-3.40N/A77.59N/A
73 Rgl3 | ER1a | (HeartE12) | (HeartE11)1.331.022.58N/A97.48N/A
74 Fance | ER1b | (HeartE12) | (HeartE11)1.201.102.53N/A90.67N/A
75 Slc26a10 | ER1c | (HeartE12) | (HeartE11)1.121.573.41N/A73.03N/A
76 Unkl | ER1a | (HeartE12) | (HeartE11)1.181.222.78N/A83.45N/A
77 Fbxl20 | ER2a | (HeartE12) | (HeartE11)1.181.152.61N/A87.38N/A
78 Magmas | ER2a | (HeartE12) | (HeartE11)1.401.022.69N/A98.14N/A
79 Zcchc18 | ER1b | (HeartE12) | (HeartE11)1.031.172.39N/A84.90N/A
80 Eif2s3x | ER4a | (HeartE12) | (HeartE11)-1.43-1.18-3.20N/A87.30N/A
81 Ccdc88c | ER1b | (HeartE12) | (HeartE11)1.221.222.84N/A84.14N/A
82 Reep6 | ER1b | (HeartE12) | (HeartE11)2.281.155.58N/A92.44N/A
83 Rnf180 | ER4a | (HeartE12) | (HeartE11)1.901.094.05N/A94.44N/A
84 Lynx1 | ER1a | (HeartE12) | (HeartE11)1.211.272.92N/A81.95N/A
85 Rps8 | ER1b | (HeartE12) | (HeartE11)1.151.072.38N/A92.37N/A
86 H2-gs10 | ER1b | (HeartE12) | (HeartE11)1.061.112.31N/A89.22N/A
87 Ikbkg | ER2a | (HeartE12) | (HeartE11)1.381.082.81N/A93.21N/A
88 Neil1 | ER1a | (HeartE12) | (HeartE11)1.341.283.23N/A82.60N/A
89 Hook2 | ER1a | (HeartE12) | (HeartE11)1.171.232.77N/A83.33N/A
90 Col25a1 | ER39a | (HeartE12) | (HeartE11)1.451.403.83N/A80.00N/A
91 Ttn | ER116a | (HeartE12) | (HeartE11)-1.25-1.16-2.76N/A87.01N/A
92 Osbpl6 | ER13a | (HeartE12) | (HeartE11)1.061.112.31N/A89.11N/A
93 Polr3e | ER1a | (HeartE12) | (HeartE11)1.181.092.47N/A91.34N/A
94 Slc41a2 | ER1a | (HeartE12) | (HeartE11)1.051.362.82N/A77.17N/A
95 Acss2 | ER1a | (HeartE12) | (HeartE11)1.261.112.65N/A90.52N/A
96 Foxo3 | ER2a | (HeartE12) | (HeartE11)1.331.142.88N/A88.95N/A
97 Hook2 | ER2a | (HeartE12) | (HeartE11)1.051.232.54N/A82.10N/A
98 Adamtsl5 | ER1a | (HeartE12) | (HeartE11)1.141.172.58N/A85.83N/A
99 Ctf1 | ER1a | (HeartE12) | (HeartE11)1.381.283.35N/A82.85N/A
100 Hnrnpa3 | ER10b | (HeartE12) | (HeartE11)-1.08-1.22-2.58N/A82.42N/A
101 Mkrn1 | ER1a | (HeartE12) | (HeartE11)1.131.232.68N/A82.87N/A
102 Rpl22l1 | ER2a | (HeartE12) | (HeartE11)1.031.052.14N/A93.61N/A
103 Dhrs13 | ER1a | (HeartE12) | (HeartE11)1.001.062.12N/A92.82N/A
104 1700029G01Rik | ER4a | (HeartE12) | (HeartE11)1.211.282.96N/A81.38N/A
105 Prrg3 | ER1a | (HeartE12) | (HeartE11)1.441.233.31N/A85.50N/A
106 Irf8 | ER1a | (HeartE12) | (HeartE11)1.141.222.71N/A83.12N/A
107 Arl5c | ER2a | (HeartE12) | (HeartE11)1.491.283.61N/A83.67N/A
108 Rpl12 | ER1d | (HeartE12) | (HeartE11)1.031.092.23N/A90.09N/A
109 H2-T24 | ER3a | (HeartE12) | (HeartE11)1.241.142.70N/A88.16N/A
110 Plscr2 | ER4b | (HeartE12) | (HeartE11)-1.31-1.46-3.60N/A77.28N/A
111 Lyst | ER1a | (HeartE12) | (HeartE11)1.341.082.74N/A92.92N/A
112 Rpl10a | ER3a | (HeartE12) | (HeartE11)1.581.193.56N/A87.71N/A
113 Irx2 | ER1d | (HeartE12) | (HeartE11)1.451.343.66N/A81.73N/A
114 Aox1 | ER6a | (HeartE12) | (HeartE11)1.291.623.94N/A74.10N/A
115 Arl4d | ER1a | (HeartE12) | (HeartE11)1.221.283.00N/A81.47N/A
116 Elavl4 | ER6b | (HeartE12) | (HeartE11)1.331.132.85N/A89.36N/A
117 Ttn | ER114a | (HeartE12) | (HeartE11)-1.54-1.16-3.37N/A88.93N/A
118 Tspyl3 | ER1a | (HeartE12) | (HeartE11)1.031.232.52N/A81.67N/A
119 Nmnat2 | ER7a | (HeartE12) | (HeartE11)1.081.402.95N/A76.49N/A
120 Rfwd2 | ER2a | (HeartE12) | (HeartE11)-1.25-1.04-2.48N/A95.44N/A
121 Padi2 | ER4a | (HeartE12) | (HeartE11)1.271.192.89N/A85.67N/A
122 Hyi | ER3a | (HeartE12) | (HeartE11)1.011.282.58N/A79.21N/A
123 Acp5 | ER6b | (HeartE12) | (HeartE11)-1.03-1.34-2.73N/A77.57N/A
124 H2-gs10 | ER2c | (HeartE12) | (HeartE11)1.561.113.25N/A92.09N/A
125 Cadm1 | ER9a | (HeartE12) | (HeartE11)-1.16-1.02-2.29N/A97.27N/A
126 Taf8 | ER1a | (HeartE12) | (HeartE11)1.441.052.85N/A95.28N/A
127 Mrpl12 | ER1a | (HeartE12) | (HeartE11)1.041.162.38N/A85.45N/A
128 Hgf | ER2a | (HeartE12) | (HeartE11)1.221.082.52N/A92.30N/A
129 6430548M08Rik | ER1b | (HeartE12) | (HeartE11)1.281.253.03N/A83.31N/A
130 Abcc9 | ER2a | (HeartE12) | (HeartE11)1.041.132.32N/A87.11N/A
131 Gtpbp10 | ER3a | (HeartE12) | (HeartE11)-1.13-1.23-2.69N/A82.75N/A
132 Cacng8 | ER4a | (HeartE12) | (HeartE11)1.131.292.81N/A80.43N/A
133 Ass1 | ER3a | (HeartE12) | (HeartE11)1.041.453.00N/A74.54N/A
134 Nt5dc3 | ER1a | (HeartE12) | (HeartE11)1.081.092.31N/A90.38N/A
135 Card6 | ER1a | (HeartE12) | (HeartE11)1.021.082.19N/A91.09N/A
136 Tob1 | ER1a | (HeartE12) | (HeartE11)1.091.122.39N/A88.37N/A
137 Col25a1 | ER5b | (HeartE12) | (HeartE11)1.711.404.56N/A81.91N/A
138 Hnrnpa3 | ER8a | (HeartE12) | (HeartE11)-1.30-1.22-3.02N/A84.52N/A
139 Col25a1 | ER4a | (HeartE12) | (HeartE11)1.641.404.35N/A81.43N/A
140 Tpt1 | ER2a | (HeartE12) | (HeartE11)1.601.023.08N/A98.60N/A
141 Kcnj15 | ER2b | (HeartE12) | (HeartE11)1.101.613.45N/A72.25N/A
142 Kcnq4 | ER6a | (HeartE12) | (HeartE11)1.021.222.48N/A81.90N/A
143 Myh7b | ER6a | (HeartE12) | (HeartE11)1.261.002.39N/A99.86N/A
144 RP23-57F11.1 | ER4c | (HeartE12) | (HeartE11)-2.39-1.32-6.90N/A87.39N/A