Group Members

The various members of the Jones Group and their research interests

 

Erin Pleasance

Erin Pleasance

Staff Scientist

The use of genomics for cancer medicine is the focus of my research interests. As a Staff Scientist, I am currently involved in the Personalized OncoGenomics (POG) project, a collaboration between researchers in bioinformatics and genomics, clinicians, and pathologists that uses genomic technologies to contribute to personalized cancer therapy decision making at the BC Cancer Agency. In recent years, I have also been involved in The Cancer Genome Atlas (TCGA) and various cancer sequencing projects funded through the National Cancer Institute. I completed my PhD in medical genetics at the GSC with Dr. Steve Jones, followed by postdoctoral work at the Sanger Institute in the UK with Sir Mike Stratton, sequencing some of the first cancer genomes. 

Yaoqing Shen

Yaoqing Shen

Staff Scientist

 

Martin Jones

Martin Jones

Staff Scientist

Over the last 10 years we have experienced a revolution in genome sequencing. Increasingly the field is exploring the practicalities and implications of applying genomic analysis to human health. With the wealth of available data the challenge now is how to apply big data approaches to data interpretation and deliverables that will have a significant and relevant impact on individual health. My interest lies in how to connect a patients genomic information with current domain knowledge in a therapeutically relevant time-frame.

Sreeja Leelakumari

Sreeja Leelakumari

Postdoctoral Fellow

As a postdoctoral research fellow, I have been working with the drug discovery platform in the development of small molecule inhibitors in lymphoma. I work with a team of computational biologists who are involved in the structure-based drug design on protein targets in cancer.

I have been involved in the cell line screening to determine the selectivity and efficiency of small molecule inhibitors and validating their mechanism of action by utilizing multiple protein assays.

I have also been involved in the BC Cancer agency’s Personalized OncoGenomics project in the analysis and interpretation of whole genome data  to guide diagnosis and treatment of patients with advanced malignancies. Together we focus to balance the Importance of Laptop to Bench Top Discoveries with Bedside Application

Jake Lever

Jake Lever

PhD Student

My research interests focus on large-scale data mining for personalised cancer genomics. I work on several large-scale text-mining and knowledge discovery projects which concentrate on identifying and predicting relationships between drugs, diseases and other terms. I'm also part of the TFRI Glioblastoma project that aims to identify two drugs for human trials. My focus is on correlating genomic abnormalities in brain tumors with drug response in order to create biomarkers to decide treatment. I graduated with a B.Eng. in Software Engineering from the University of Edinburgh with an exchange year at Caltech.

Eric Zhao

Eric Zhao

MD/PhD Student

I am an MD/PhD student involved with the Personalized Oncogenomics Project. My research aim is to uncover new biomarkers linking DNA repair deficiencies and personalized cancer therapy. To do this, I am conducting translational cancer research using whole genome sequencing, and developing new Bayesian machine learning methods for mutation signature analysis in a clinical setting. Outside of the lab, I am involved in health innovation and advocacy.

 

Previous Members

 

Santina Lin

Santina Lin

Masters Rotation Student

Current Position: Software Engineer at Microsoft

 

Question Mark

Celia Siu

Masters Rotation Student

Current Position: Data Engineer at Visier Inc.

Daryanaz Dargahi

Daryanaz Dargahi

PhD Student

Current Position: Associate Scientist, Bioinformatics, at Zymeworks

Jeremy Chan

Jeremy Chan

Undergraduate Co-op Student

As an undergraduate co-op student, I worked to support my supervisor, Sreeja, with various daily experiments and tasks relating to lymphoma. Working with the Jones Group at the Genome Sciences Centre has opened my eyes to the potential and impact of cancer research, thus this co-op experience has definitely started to provide an idea and shape my research interest for the future.  I will be returning to the University of British Columbia to complete my Bachelor of Science degree specializing in Biochemistry after my co-op work term. 

Pinaki Bose

Pinaki Bose

Postdoctoral Fellow (2014-2015)

Current Position: Assistant Professor, University of Calgary (link)

Page last modified Jan 29, 2018