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Robert Holt Publications

Robert Holt Complete Bibliography
  1. The Cancer Genome Atlas Research Network. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med. 2016 Jan 14;374(2):135-45. 
  2. Brown SD, Raeburn LA, Holt RA. Profiling tissue-resident T cell repertoires by RNA sequencing. Genome Med. 2015 Nov 30;7(1):125.
  3. Martin SD, Coukos G, Holt RA, Nelson BH. Targeting the undruggable: Immunotherapy meets personalized oncology in the genomic era. Ann Oncol. 2015 Dec;26(12):2367-74.
  4. The Cancer Genome Atlas Research Network. Genomic Classification of Cutaneous Melanoma. Cell. 2015 Jun 18;161(7):1681-96. 
  5. The Cancer Genome Atlas Research Network. Comprehensive, Integrative Genomic Analysis of Diffuse Lower Grade GliomasThe New England Journal of Medicine. 2015 Jun 25;372(26):2481-98.
  6. Gibb EA, Warren RL, Wilson GW, Brown SD, Robertson GA, Morin GB, Holt RA. (2015). Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma. Genome Medicine. 7:22. 
  7. The Cancer Genome Atlas Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 2015 Jan 29;517(7536):576-82. 
  8. Watson C, Steinberg KM, Graves T, Warren R, Malig M, Schein J, Wilson R, Holt R, Eichler E, Breden F. Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity. Genes Immun. 2015 Jan-Feb;16(1):24-34.
  9. The Cancer Genome Atlas Research Network. Integrated Genomic Characterization of Papillary Thyroid Carcinoma. Cell. 2014 Oct 23;159(3):676-90. 
  10. The Cancer Genome Atlas Research Network. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 2014 Sep 8;26(3):319-30. 
  11. The Cancer Genome Atlas Network. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15544-9.
  12. The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014 Sep 11;513(7517):202-9.
  13. The Cancer Genome Atlas Research Network, Benz CC, Perou CM, Stuart JM. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell. 2014 Aug 14;158(4):929-44.
  14. The Cancer Genome Atlas Network. (2014). Comprehensive molecular profiling of lung adenocarcinoma. Nature. 511(7511): 543-50.
  15. Sharma G and Holt RA. (2014). T-cell epitope discovery technologies. Human Immunology. 75(6): 514-519.
  16. McKinnon ML, Rozmus J, Fung SY, Hirschfeld AF, Del Bel KL, Thomas L, Marr N, Martin SD, Marwaha AK, Priatel KK, Tan R,7 other authors,Holt RA and 3 other authors. (2014). Combined immunodeficiency associated with homozygous MALT1 mutations. J Allergy Clin Immunol. 133(5): 1458-1462.
  17. Brown SD, Warren RL, Gibb E, Martin SD, Spinelli JJ, Nelson BH, Holt RA. (2014). Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival. Genome Research. 24(5): 743-50.
  18. The Cancer Genome Atlas Network. (2014). Comprehensive molecular characterization of urothelial bladder carcinoma. Nature. 507(7492): 315-322.
  19. Wick D, Webb JR, Nielsen JS, Martin S, Kroeger DR, Milne K, Castellarin M, Twumasi-Boating K, Watson PH, Holt RA, Nelson BH. (2014). Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer. Clinical Cancer Research. 20(5): 1125-34.
  20. De Leeuw CN, Dyka FM, Boye SL, Laprise S, Zhou M, Chou AY, Boretta L, McInerny SC, Banks KG, Portales-Casamar E, Swanson MI, D’Souza CA, Boye SE, Jones SJM, Holt RA, and 3 other authors. (2014). Targeted CNS Delivery using human MiniPromoters and demonstrated compatibility with adenoassociated viral vectors. Molecular Therapy – Methods and Clinical Development. 1: 5.
  21. Bosdet I, Docking R, Butterfield Y, Mungall A, Zeng T, Coope R, Yorida E, Chow K, Young S, Hirst M, Birol I, Moore R, Jones S, Holt R, Karsan A. (2013). A clinically validated diagnostic second-generation sequencing assay for detection of hereditary BRCA1 and BRCA2 mutations.Journal of Molecular Diagnostics. 15(6): 796-809.
  22. Schmouth JF, Castellarin M, Laprise S, Banks KG, Bonaguro RJ, McInerny SC, Borretta L, Amirabbasi M, Korecki AJ, 3 other authors, Jones SJM, Wasserman WW, Goldowitz D, Holt RA, Simpson EM. (2013). Non-coding regulatory regions of human brain genes delineated by BAC knock-in mice. BMC Biology. 11(1): 106.
  23. Woodsworth DJ, Castellarin M, Holt RA. (2013). Sequence analysis of T-cell repertoires in health and disease. Genome Medicine. 5(10): 98.
  24. The Cancer Genome Atlas Research Network. (2013). The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 45(10): 113-20.
  25. Morin RD, Mungall K, 23 other authors, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD, Marra MA. (2013). Mutational and structural analysis of diffuse large B-cell lymphoma using whole genome sequencing. Blood. 122(7): 1256-65.
  26. The Cancer Genome Atlas Network. (2013). Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 499(7456): 43-9.
  27. Reinke SN , Resch L , Maingat F , Branton W , Jackson AC , Holt R , Slupsky C , Marrie T , Sykes BD , Power C. (2013). Metagenomic and Metabolomic Characterization of Rabies Encephalitis: New Insights into the Treatment of an Ancient Disease. The Journal of infectious diseases. 207(9): 1451-6.
  28. The Cancer Genome Atlas Network. (2013). The Genomic and Epigenomic Landscape of Adult de novo Acute Myeloid Leukemia. New England Journal of Medicine. 368(22): 2059-74.
  29. Warren RL, Freeman DJ, Pleasance S, Watson P, Moore RA, Cochrane K, Allen-Vercoe E, Holt RA. (2013). Co-occurrence of anaerobic bacteria in colorectal carcinomas. Microbiome. 1(1): 16.
  30. The Cancer Genome Atlast Network. (2013). Integrated Genomic Characterization of Endometrial Carcinoma. Nature. 497(7447): 67-73.
  31. Watson CT, Steinberg KM, Huddleston J, Sudmant P, Warren RL, Malig M, Schein J, Willsey JA, Joy JB, Scott JK, Graves, Wilson RK, Holt RA, Eichler EE, Breden F. (2013). Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. American Journal of Human Genetics. 92(4): 530-46.
  32. Castellarin M , Milne K , Zeng T , Tse K , Mayo M , Zhao Y , Webb JR , Watson PH , Nelson BH , Holt RA. (2013). Clonal evolution of high-grade serous ovarian carcinoma from primary to recurrent disease. The Journal of pathology. 229(4): 515-24.
  33. Branton WG, Ellestad KK, Maingat F, Wheatley BM, Rud E, Warren RL, Holt RA, Surrete MG, Power C. (2013). Brain Microbial Population in HIV/AIDS: α-Proteobacteria Predominate Independent of Host Immune Status. PLoS One. 8(1): e54673.
  34. Warren RL, Choe G, Freeman DJ, Castellarin M, Munro S, Moore R, Holt RA. (2012). Derivation of HLA types from shotgun sequence datasets. Genome Medicine. 4(12): 95.
  35. The Cancer Genome Atlas Network.  Comprehensive molecular portraits of human breast cancer tumours.  Nature. 2012 Oct 4;490(7418):61-70.
  36. Castellarin M, Milne K, Zeng T, Tse K, Mayo M, Zhao YJ, Webb JR, Watson PH, Nelson BH, Holt RA Clonal evolution of high-grade serous ovarian carcinoma from primary to recurrent diseaseJournal of Pathology21 September 2012
  37. Reinke SN, Resch L, Maingat F, Branton W, Jackson A, Saxinger L, Holt RA, Slupsky C, Marrie T, Sykes BD, Power C.  Metagenomic and metabolomic characterization of rabies encephalitis – new insights into the treatment of an ancient diseaseJournal of Infectious Diseases. 2013 May 1;207(9):1451-6.
  38. Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, Dubuc A, Yao Y, Ramaswamy V, Luu B, Rolider A, Cavalli FM, Wang X, Remke M, Wu X, Chiu RY, Chu A, Chuah E, Corbett RD, Hoad GR, Jackman SD, Li Y, Lo A, Mungall KL, Nip KM, Qian JQ, Raymond AG, Thiessen NT, Varhol RJ, Birol I, Moore RA, Mungall AJ, Holt R, Kawauchi D, Roussel MF, Kool M, Jones DT, Witt H, Fernandez-L A, Kenney AM, Wechsler-Reya RJ, Dirks P, Aviv T, Grajkowska WA, Perek-Polnik M, Haberler CC, Delattre O, Reynaud SS, Doz FF, Pernet-Fattet SS, Cho BK, Kim SK, Wang KC, Scheurlen W, Eberhart CG, Fèvre-Montange M, Jouvet A, Pollack IF, Fan X, Muraszko KM, Gillespie GY, Di Rocco C, Massimi L, Michiels EM, Kloosterhof NK, French PJ, Kros JM, Olson JM, Ellenbogen RG, Zitterbart K, Kren L, Thompson RC, Cooper MK, Lach B, McLendon RE, Bigner DD, Fontebasso A, Albrecht S, Jabado N, Lindsey JC, Bailey S, Gupta N, Weiss WA, Bognár L, Klekner A, Van Meter TE, Kumabe T, Tominaga T, Elbabaa SK, Leonard JR, Rubin JB, Liau LM, Van Meir EG, Fouladi M, Nakamura H, Cinalli G, Garami M, Hauser P, Saad AG, Iolascon A, Jung S, Carlotti CG, Vibhakar R, Ra YS, Robinson S, Zollo M, Faria CC, Chan JA, Levy ML, Sorensen PH, Meyerson M, Pomeroy SL, Cho YJ, Bader GD, Tabori U, Hawkins CE, Bouffet E, Scherer SW, Rutka JT, Malkin D, Clifford SC, Jones SJ, Korbel JO, Pfister SM, Marra MA, Taylor MD. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 2012 Aug 2; 488(7409):49-56
  39. The Cancer Genome Atlast Network.  Comprehensive molecular characterization of human colon and rectal cancerNature.  2012 Jul 18; 478(7407):330-7
  40. Schmouth JF, Banks KG, Mathelier A, Gregory-Evans CY, Castellarin M, Holt RA, Gregory-Evans K, Wasserman WW, Simpson EM.  Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null miceMolecular Cell Biology.  2012 Apr;32(7):1296-311
  41. Castellarin M*, Warren RL*, Freeman JD, Dreolini L, Krzywinski M, Strauss J, Barnes R, Watson P, Allen-Vercoe E, Moore RA, Holt RAFusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Research. 2012 Feb;22(2):299-306.  *Commentary in Cell 147:1205 (2011) and Nature Reviews Gastroenterology 8:6 (2011).
  42. Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M, Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, Li S, Firme MR, Rogic S, Griffith M, Chan S, Yakovenko O, Meyer IM, Zhao EY, Smailus D, Moksa M, Chittaranjan S, Rimsza L, Brooks-Wilson A, Spinelli JJ, Ben-Neriah S, Meissner B, Woolcock B, Boyle M, McDonald H, Tam A, Zhao Y, Delaney A, Zeng T, Tse K, Butterfield Y, Birol I, Holt RA, Schein J, Horsman DE, Moore RA, Jones SJM, Connors JM, Hirst M, Gascoyne RD, Marra MA.  Frequent mutation of histone-modifying genes in non-Hodgkin lymphomaNature. 2011 Jul 27 ;476(7360):298-303.
  43. Moore RA, Warren RL, Freeman JD, Gustavsen JA, Chenard C, Friedman JM, Suttle CA, Zhao Y, Holt RA. The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissuesPLoS One. 2011;6(5):e19838. Epub 2011 May 13.
  44. Warren RL, Holt RATargeted assembly of short sequence readsPLoS One. 6(5):e19816.11 May 2011.
  45.  Warren RL, Freeman JD, Zeng T, Choe G, Munro S, Moore R, Webb JR, Holt RA. Exhaustive T- cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes. Genome Research.21(5):790-7. 2011 May.
  46. Bhat RK, Ellestad KK, Wheatley BM, Warren R, Holt RA, Power C. Age- and disease-dependent HERV-W envelop allelic variation in brain: association with neuroimmune gene expression. PLoS One. 6(4):e19176. 2011 Apr 29.
  47. DiGuistini S, Wang Y, Liao NY, Taylor G, Tanguay P, Feau N, Henrissat B, Chan SK, Hesse-Orce U, Massoumi Alamouti S, Tsui CK, Docking TR, Levasseur A, Haridas S, Robertson G, Birol I, Holt RA, Marra MA, Hamelin RC, Hirst M, Jones SJM, Bohlmann J, Breuil C.  Genome and transcriptome analyses of the mountain pine beetlefungal symbiont Grosmannia clavigera, a lodgepole pine pathogenGenome.  108(6):2504-9. 2011 February 8.
  48. Kronstad JW, D’Souza CA, Taylor G, Warren R, Hao H, Yuen M, Hu G, Jung WH, Sham A, Kidd S, Tangen K, Lee N, Zeilmaker T, Sawkins J, McVicker G, Shah S, Gnerre S, Griggs A, Zeng Q, Bartlett K, Li W, Wang X, Heitman J, Stajich J, Fraser J, Meyer W, Carter D, Schein J, Krzywinski M, Kwong Chung KJ, Varma A, Wang J, Fyfe M, Ouellette BFF, Siddiqui A, Marra M, Jones S, Holt RA, Birren BW, Galagan JE and Cuomo CA. Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. MBio. 8;2(1) 2011 February.
  49. Gardy JL, Johnston JC, Ho Sui SJ, Cook VJ, Shah L, Brodkin E, Rempel S, Moore R, Zhao Y, Holt RA, Varhol R, Birol I, Lem M and Sharma M. Whole Genome Sequencing and Social Network Analysis of a Tuberculosis Outbreak. New England Journal of Medicine. 364(8):730-9. 24 February 2011
  50. Horspool DR, Coope RJand Holt RA. Efficient assembly of very short oligonucleotides using T4 DNA Ligase. BMC Research Notes. 3(1):291. 2010 November
  51.  Hesse-Orce U, Diguistini S, Keeling CI, Wang Y, Li M, Henderson H, Docking R, Liao NY, Robertson G, Holt RA, Jones SJ, Bohlmann J, Breuil C. Gene discovery for the bark beetle-vectored fungal tree pathogen Grosmannia clavigera. BMC Genomics. 4;11(1):536. 2010 October.
  52. Portales-Casamar E, Swanson DJ, Liu L, de Leeuw CN, Banks KG, Ho Sui SJ, Fulton DL, Ali J, Amirabbasi M, Arenillas DJ, Babyak N, Black SF, Bonaguro RJ, Brauer E, Candido TR, Castellarin M, Chen J, Chen Y, Cheng JC, Chopra V, Docking TR, Dreolini L, D'Souza CA, Flynn EK, Glenn R, Hatakka K, Hearty TG, Imanian B, Jiang S, Khorasan-zadeh S, Komljenovic I, Laprise S, Liao NY, Lim JS, Lithwick S, Liu F, Liu J, Lu M, McConechy M, McLeod AJ, Milisavljevic M, Mis J, O'Connor K, Palma B, Palmquist DL, Schmouth JF, Swanson MI, Tam B, Ticoll A, Turner JL, Varhol R, Vermeulen J, Watkins RF, Wilson G, Wong BK, Wong SH, Wong TY, Yang GS, Ypsilanti AR, Jones SJ, Holt RA, Goldowitz D, Wasserman WW, Simpson EM. A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proceedings of the National Academy of Sciences. 21;107(38):16589-94. 2010 September.
  53. Zhou W, Cai F, Li Y, Yang GS, O'Connor KD, Holt RA, Song W.  BACE1 Gene Promoter Single-Nucleotide Polymorphisms in Alzheimer's DiseaseJournal of Molecular Neuroscience. 42(1):127-133. 2010 Sep.
  54. Jones SJM, Laskin J, Li YY, Griffith OL, An J, Bilenky M, Butterfield YS, Cezard T, Chuah E, Corbett R, Fejes A,  Griffith M, Yee J, Montgomery M, Mayo M, Melnyk N, Morin RD,  Pugh TJ, Severson T, Shah SP, Sutcliffe M, Tam A, Terry J, Thiessen N, Thomson T, Varhol R, Zeng T, Zhao YJ, Moore RA, Huntsman DG, Birol I, Hirst M, Holt RA, Marra MA. Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biology. 9;11(8):R82. 2010 Aug.
  55. Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, Yap D, Humphries RK, Griffith OL, Shah S, Zhu H, Kimbara M, Shashkin P, Charlot JF, Tcherpakov M, Corbett R, Tam A, Varhol R, Smailus D, Moksa M, Zhao Y, Delaney A, Qian H, Birol I, Schein J, Moore R, Holt R, Horsman DE, Connors JM, Jones S, Aparicio S, Hirst M, Gascoyne RD, Marra MA. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nature Genetics. 42(2):181-185. 2010 Feb.
  56. Balasundaram M, Tsai M, Clarke A, Leung D, Munro S, Wagner S, Michael M, Moore R, Holt RA. A quality management system application to investigate and troubleshoot process failures: A case Study of the BC Cancer Agency. Clinical Governance. 15:2.2010.
  57. Leong JS, Jantzen SG, von Schalburg KR, Cooper GA, Messmer Am,  Liao NY, Munro S, Moore R, Holt RA, Jones SJM, Davidson WS, Koop BF.  Salmo salar and Esox lucius full-length cDNA clones reveal changes in evolutionary pressures on a post-tetraploidization genomeBMC Genomics. 11(1):279. 2010 Apr 30.
  58. Mead CL, Kuzyk MA, Moradian A, Wilson GM, Holt RA, Morin GB. Cytosolic protein interactions of the schizophrenia susceptibility gene dysbindin. Journal of Neurochemistry. 113(6):1491-1503. 2010 Jun.
  59. Warren RL and Holt RAA census of predicted mutational epitopes suitable for immunologic cancer controlHuman Immunology.  71(3):245-254. 2010 Mar. 
  60. Romanuik TL, Wang G, Holt RA, Jones SJM, Marra MA, Sadar M.  Identification of novel androgen-responsive genes by sequencing of LongSAGE librariesBMC Genomics. 10:476. 2009.
  61. Shah SP, Morin R, Khattra J, Prentice L, Pugh T, Burleigh A, Delaney A, Gelmon K, Guliany R, Senz J, Steidl C, Holt RA, Jones S, Sun M, Leung G, Moore R, Severson T, Taylor G, Teschendorff AE, Tse K, Turashvili G, Varhol R, Warren RL, Watson P, Zhao Y, Caldas C, Huntsman D, Hirst M, Marra MA, Aparicio S. Mutational evolution and RNA editing in a lobular breast tumour profiled at single nucleotide resolution. Nature.461:809-813. 2009.
  62. The MGC Project Teams (incl Hirst M, Zeng T, Tse K, Moksa M, Deng M, Ma K, Mah D, Pang J, Taylor G, Chuah E, Deng A, Fichter K, Go A, Lee S, Wang J, Griffith M, Morin R, Moore RA, Mayo M, Munro S, Wagner S, Jones SJM, Holt RA, Marra MA). The Completion of the Mammalian Gene Collection (MGC). Genome Research. 19: 2324-2333. 2009.
  63. Diguistini S, Liao NY, Platt D, Robertson G, Seidel M, Chan SK, Docking TR, Birol I, Holt RA, Hirst M, Mardis E, Marra MA, Hamelin RC, Bohlmann J, Breuil C, Jones SJ. De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data. Genome Biology.  10(9):R94. 2009 Sep 11.
  64. Pel J, Broemeling D, Mai L, Poon HL, Tropini G, Warren RL, Holt RA, Marziali A. Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules. Proceedings of the National Academy of Sciences. 1;106(35):14796-14801. 2009.
  65. Freeman JD, Warren RL, Webb JR, Nelson BH, Holt RA. Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing. Genome Research. 19(10):1817-18124. 2009. 
  66. Wang X, Zhao Y, Wong K, Ehlers P, Kohara Y, Jones SJ, Marra MA, Holt RA, Moerman DG, Hansen D. Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE. BMC Genomics. 9;10:213. 2009.
  67. The Bovine Genome Sequencing and Analysis Consortium (incl  Chiu R, Jones S, Marra M, Holt RA, Moore R, & Schein J). The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution. Science. 24;324(5926):522-528. 2009.
  68. Meissner B, Warner A, Wong K, Dube N, Lorch A, McKay SJ, Khattra J, Rogalski T, Somasiri A, Chaudhry I, Fox RM, Miller DM 3rd, Baillie DL, Holt RA, Jones SJ, Marra MA, Moerman DG. An Integrated Strategy to Study Muscle Development and Myofilament Structure in Caenorhabditis elegans. Public Library of Science Genetics. 5(6):e1000537. 2009.
  69. Warren RL, Nelson BH, Holt RAProfiling model T-cell metagenomes with short reads. Bioinformatics. 25(4):458-464. 2009 Feb 15.
  70. Yang GS, Banks KG, Bonaguro RJ, Wilson G, Dreolini L, de Leeuw CN, Liu L, Swanson DJ, Goldowitz D, Holt RA, Simpson EM. Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus. Genomics. 93(3):196-204. 2009.
  71. D'Souza CA, Chopra V, Varhol R, Xie YY, Bohacec S, Zhao Y, Lee LL, Bilenky M, Portales-Casamar E, He A, Wasserman WW, Goldowitz D, Marra MA, Holt RA, Simpson EM, Jones SJ.  Identification of a set of genes showing regionally enriched expression in the mouse brain. BMC Neuroscience. 14:9:66. 2008.
  72. Warren RL, Freeman JD, Levesque RC, Smailus DE, Flibotte S, Holt RA. Transcription of foreign DNA in Escherichia coli. Genome Research. 18:1798-1805. 2008. 
  73. Koop BF, von Schalburg KR, Leong J, Walker N, Lieph R, Cooper GA, Robb A, Beetz-Sargent M, Holt RA, Moore R, Brahmbhatt S, Rosner J, Rexroad III CE, McGowan CR and Davidson WS.  A salmonid EST genomic study: genes, duplications, phylogeny and microarraysBMC Genomics. 9:545. 2008.
  74. Holt RA and Jones SJM.  The new paradigm of flow cell sequencing. Invited review article. Genome Research. 18:839-846. 2008.
  75. Smailus DE, Warren R L and Holt RA. Constructing large DNA segments by iterative clone recombinationSystems and Synthetic Biology. 1;139-144. 2008.
  76. Cai F, Chen B, Zhou W, Zis O, Liu S, Holt RA, Honer GW, Song W.  SP1 regulates the human SNAP-25 gene expressionJournal of Neurochemistry. 105;512-523. 2008. 
  77. Mead CR, Morin GB, Holt RA, Pathway analysis in complex disease.  In Thangadurai D., Tang W., Pullaiah T. (eds.), Genomics and Proteomics. Regency Publications, New Delhi.  Chapter 13; p217-225. 2008
  78. Ralph S, Chun H, Cooper D, Kirkpatrick R, Kolosova N, Gunter L, Tuskan G, Douglas C, Holt R, Jones S, Marra M, Bohlmann J.  Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feedingBMC Genomics. 9:57. 2008.
  79. von Schalburg KR, Leong J, Cooper GA, Robb A, Beetz-Sargent MR, Lieph R, Holt RA, Moore R, Ewart KV, Driedzic WR, Ten Hallers BF, Zhu B, de Jong PJ, Davidson WS, Koop BF.  Rainbow Smelt (Osmerus mordax) Genomic Library and EST ResourcesMarine Biotechnology. 10(5): 487-491. 2008.
  80. Snelling WM, Chiu R, Schein JE, Hobbs M, Abbey CA, Adelson DL, Bennett GL, Bosdet IE, Boussaha M, Brauning R, Caetano AR, Costa MM, Crawford AM, Dalrymple BP, Eggen A, Everts-van der Wind A, Floriot S, Gautier M, Gill CA, Green RD, Holt RA, Jones SJM, Kappes SM, Keele JW, de Jong PJ, Larkin DM, Lewin HA, McEwan JC, McKay S, McWilliam S, Marra MA, Mathewson CA, Matukumalli LK, Moore SS, Murdoch B, Nicholas F, Osoegawa K, Roy A, Salih H, Schibler L, Schnabel R, Silveri L, Skow LC, Smith TPL, Sonstegard TS, Taylor J, Tellam R, Van Tassell CP, Williams JL, Womack JE, Wye NH, Yang G, Zhao S. A physical map of the bovine genome. Genome Biology. 14;R165. 2007 
  81. Holt RA, Warren R, Flibotte S, Missirlis PI and Smailus DE. Rebuilding microbial genomes. Bioessays.29: 580-590. 2007.
  82. Butland SL, Devon RS, Huang Y, Mead CL, Meynert AM, Neal SJ, Lee SS, Wilkinson A, Yang GS, Yuen MMS, Hayden MR, Holt RA, Leavitt BR and Ouellette BFF. CAG-encoded polyglutamine length polymorphism in the human genome. BMC Genomics.  8:126. 2007.
  83. Warren RL, Sutton GG, Jones SJM and Holt RA. Assembling millions of short DNA sequences using SSAKE. Bioinformatics. 23: 500-501. 2007. 
  84. Hirst M, Delaney A, Rogers SA, Schnerch A, Persaud DR, O’Connor MD, Zeng T, Moksa M, Fichter K, Mah D, Go A, Morin RD, Baross A, Zhao Y, Khattra J, Prabhu A-L, Pandoh P, McDonald H, Asano J, Dhalla N, Ma K, Lee S, Ally A, Chahal N, Menzies S, Siddiqui A, Holt RA, Jones S, Gerhard DS, Thomson JA, Eaves CJ and Marra MA. LongSAGE transcriptome analysis of nine human embryonic stem cell lines reveals novel transcripts and an over-representation of RNA binding proteins. Genome Biology. 8:R113. 2007. 
  85. Kelleher CT, Chiu R. Shin H, Bosdet IE, Krzywinski MI, Fjell CD, Wilkin J, Yin TM, DiFazio SP, Ali J, Asano JK, Chan S, Cloutier A, Girn N, Leach S, Lee D, Mathewson CA, Olson T, O’Connor K, Pradhu A-L, Smailus DE, Stott JM,  Tsai M, Wye NH, Yang GS, Zhuang J, Holt RA, Putnam NH, Vrebalov J, Giovannoni JJ, Grimwood J, Schmutz J, Rokhsar D, Jones SJM, Marra MA, Tuskan GA, Bohlmann J, Ellis BE, Ritland K, Douglas CJ and Schein JE. A physical map of the highly heterozygous Populus genome: integration with the genome sequence and genetic map and analysis of haplotype variation. The Plant Journal. 50:1063-1078. 2007.
  86. Khattra J, Delaney AD, Zhao Y, Siddiqui A, Hirst M, Asano J, McDonald H, Pandoh P, Dhalla N, Prabhu A, Ma K, Lee S, Ally A, Tam A, Sa D, Rogers S, Charest D, Stott J, Zuyderduyn S, Varhol R, Jones S, Holt RA, Hoodless P and  Marra MA. Large scale production of SAGE libraries from microdissected tissues, flow-sorted cells and cell lines. GenomeResearch. 17:108-116. 2007.
  87. Peng FY, Reid KE, Liao N, Schlosser J, Holt RA, Martínez Zapater JM, Jones S, Marra M, Bohlmann J, Lund ST. Generation of ESTs in Vitis vinifera wine grape (Cabernet Sauvignon) and table grape (Muscat Hamburg) and discovery of new candidate genes with potential roles in berry development. Gene. 402:40-50. 2007.
  88. Etchberger JF, Lorch  A, Sleumer  M, Zapf  R, Jones  SJ, Marra  MA, Holt RA, Moerman  DG, Hobert O. The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. Genes and Development. 21:1653-1674. 2007.
  89. DiGustini S, Ralph S, Lim Y, Holt RA, Jones S, Bohlmann J and Breuil C.  Generation and annotation of lodgepole pine and oleoresin induced expressed sequences from the blue-stain fungus Ophiostoma cavigerum, a Mountain Pine Beetle associated pathogenFEMSMicrobiologyLetters.  267; 151-158. 2007.
  90. McGhee JD, Sleumer MC, Bilenky M, Wong K, McKay SJ, Goszczynski B, Tian H, Krich ND, Khattra J, Holt RA, Baillie DL, Kohara Y, Marra MA, Jones SJM, Moerman DG and Robertson AG. The ELT-2 GATA-Factor and the Global Regulation of Transcription in the C. elegans Intestine. DevelopmentalBiology. 302: 627-645. 2006.
  91. Missirlis PI, Smailus DE and Holt RAA high-throughput screen identifying sequence and promiscuity characteristics of the loxP spacer region in Cre-mediated recombinationBMC Genomics. 7:73. 2006.
  92. Wilson GM, Flibotte S, Chopra V, Melnyk BL, Honer WG and Holt RA.  DNA copy number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signingHuman Molecular Genetics.  15: 743-749.  2006.
  93. Wilson GE, Flibotte S, Missirlis PI, Marra MA, Jones S, Thornton K, Clark AG and Holt RA.  Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorillaGenomeResearch. 16:173-181. 2006.
  94. Scheinman JE, Holt RA, Auerbach MR, Stewart CB.  Duplication and Divergence of Two Distinct Pancreatic Ribonuclease Genes in Leaf-Eating African and Asian Colobine MonkeysMolecular Biology and Evolution. 23:1465-1479.2006.
  95. Morin RD, Chang E, Petrescu A, Liao N, Griffith M, Kirkpatrick R, Butterfield YS, Young AC, Stott J, Barber S, Babakaiff R, Dickson MC, Matsuo C, Wong D, Yang GS, Smailus DE, Wetherby KD, Kwong PN, Grimwood J, Brinkley III CP, Brown-John M, Reddix-Dugue ND, Mayo M, Schmutz J, Beland J, Park M, Gibson S, Olson T, Bouffard GG, Tsai M, Featherstone R, Chand S, Siddiqui AS, Jang W, Lee E, Klein SK, Blakesley RW, Prange C, Myers RM, Green ED, Wagner K, Gerhard DS, Marra MA, Jones SJM and  Holt RASequencing and analysis of 10967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodelingGenome Research. 16:796-803. 2006.
  96. McLeod MP, Warren RL, Araki N, Hsiao WWL, Myhre M, Fernandes C, Miyazawa D, Wong W, Lillquist AL, Wang D, Dosanjh M, Hara H, Petrescu A, Morin RD, Yang G, Stott JM, Schein JE, Shin H, Smailus D, Siddiqui AS, Marra MA, Jones SJM, Holt RA, Brinkman FSL, Miyauchi K, Fukuda M, Davies JE, Mohn WW, Eltis LD.  The complete genome of Rhodoccocus sp. RHA1: insights into a catabolic powerhouseProceedings of the National Academy of Sciences.  103:15582-15587. 2006.
  97. Tuskan G, DiFazio S, Bohlmann J, Griogoriev I, Hellsten U, Jansson S, Putnam N, Ralph S, Rombauts S, Salanov A, Schein J, Sterck L, Aerts A, Bhalerao RR, Bhalerao RP, Blaudez D, Boerjan W, Brun A, Brunner A, Busov V, Campbell M, Carlson J, Chalot M, Chapman J, Chen GL, Cooper D, Coutinho P, Couturier J, Covert S, Cronk Q, Cunningham R, Davis J, Degroeve S, Déjardin A, dePamphilis C, Detter J, Dirks B, Dubchak I, Dupleissis S, Ehlting J, Ellis B, Gendler K, Goodstein D, Gribskov, Grimwood J, Groover A, Gunter L, Hamberger B, Heinze B, Helariutta Y, Henirssat B, Holligan D, Holt RA, Huang W, Islam-Faridi N, Jones S, Jones-Rhoades M, Jorgensen R, Joshi C, Kangasjärvi J, Karlsson J, Kelleher C, Kirkpatrick R, Kirst M, Kohler A,, Kalluri U, Larimer F, Leebens-Mack J, Leplé J, Locascio P, Luo Y, Lucas S, Martin F, Montanini B, Napoli C, Pilate DR, Poliakov A, Razumovskaya J, Richardson P, Rinaldi C, Ritland K, Siddiqui A, Sterky F, Terry A, Tsai C, Uberbacher E, Unneberg P, Vahala J, Wall K, Wessler S, Yang G, Yin T, Douglas C, Sandberg G, Van de Peer Y, Rokhsar D.  The Genome of Black Cottonwood  Populus trichocarpa. Science. 313:1596-1604. 2006.
  98. Friedman JM, Baross A, Delaney AD, Ally A, Arbour L, Asano J, Bailey DK, Barber S, Birch P, Brown-John M, Cao M, Chan S, Charest DL, Farnoud N, Fernandes N, Flibotte S, Go A, Gibson WT, Holt RA, Jones SJM, Kennedy GC, Krzywinski M, Langlois S, Li HI, McGillivray BC, Nayar T, Pugh TJ, Rajcan-Separovic E, Schein JE, Schnerch A, Siddiqui A, Van Allen MI, Wilson G, Yong SL, Eydoux P, Marra MA.  Oligonucleotide Microarray Analysis of Genomic Imbalance in Children with Mental Retardation. American Journal of Human Genetics.  79:500-513.2006.
  99. Ralph S, Oddy C, Cooper D, Yueh H, Jancsik S, Kolosova N, Philippe RN, Aeschliman D, White R, Huber D, Ritland CE, Benoit F, Rigby T, Nantel A, Butterfield YSN, Kirkpatrick R, Chun E, Liu J, Palmquist D, Wynhoven B, Stott J, Yang G, Barber S, Holt RA, Siddiqui A, Jones SJM, Marra MA, Ellis BE, Douglas CJ, Ritland K, Bohlmann K.  Genomics of hybrid poplar (Populus trichocarpa x deltoids) interacting with forest tent caterpillars (Malacosoma disstria): Normalized and full-length cDNA libraries, expressed sequence tags (ESTs) and a cDNA microarray for the study of insect-induced defenses in poplarMolecular Ecology.  15:1275-1297. 2006. 
  100. Siddiqui AS, Khattra J, Delaney AD, Zhao Y, Astell C, Asano J, Babakaiff R, Barber S, Beland J, Bohacec S, Brown-John M, Chand S, Charters AM, Cullum R, Dhalla N, Featherstone R, Gerhard DS, Hoffman B, Holt RA, Hou J, Kuo BYL, Lee LLC, Lee S, Leung D, Ma K, Matsuo C, Mayo M, McDonald H, Prabhu AL, Pandoh P, Riggins GJ, Ruiz de Algara T, Rupert JL, Smailus D, Stott J, Tsai M, Varhol R, Vrljiak P, Wong D, Wu MK, Xie YY, Yang G, Zhang I, Hirst M, Jones SJM, Helgason CD, Simpson EM, Hoodless PA, Marra M.  A mouse atlas of gene expression:  Large-scale digital gene expression profiles from precisely defined developing C57BL/6J mouse tissues and cellsProceedings of the National Academy of Sciences. 102: 18485-18490. 2005.
  101. Smailus DE, Marziali A, Dextras P, Marra MA and Holt RASimple, robust methods for high-throughput nanoliter-scale DNA sequencingGenome Research. 15: 1447-1450. 2005.
  102. Pavy N, Paule C, Parsons L, Crow JA, Morency MJ, Cooke J, Johnson JE, Noumen E, Guillet-Claude C, Butterfield Y, Barber S, Yang G, Liu J, Stott J, Kirkpatrick R, Siddiqui A, Holt RA, Marra M, Séguin A, Retzel E, Bousquet J and MacKay J.  Generation, annotation, analysis and database integration of 16,500 white spruce EST clustersBMC Genomics. 6:144. 2005. 
  103. Missirlis PI, Mead CL, Butland SL, Ouellette BFF, Devon RS, Leavitt BR and Holt RA.  Satellog: A database for the identification and prioritization of satellite repeats in disease association studiesBMC Bioinformatics.6:145. 2005.
  104. Blacque OE, Perens EA, Boroevich KA, Inglis PN, LiC, Warner A, Khattra J, Holt RA, Ou G, Mah AK, McKay SJ, Huang P, Swoboda P, Jones SJ, Marra MA, Baillie DL, Moerman DG, Shaham S, Leroux MR. Functional Genomics of the Cilium, A Sensory OrganelleCurrent Biology.15:935-941. 2005.
  105. Halaschek-Wiener J, Khattra JS, McKay S, Pouzyrev A, Stott JM, Yang GS, Holt RA, Jones SJM, Marra MA, Brooks-Wilson AR, Riddle DL.  Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expressionGenome Research.15:603-615.2005.
  106. Holt RA, Collins FC.  The Malaria Mosquito Genome, in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.  Ed. RA Meyers.  Wiley – VCH. Volume 7, pp 469-495. April 2005

  107. Holt RA, Krzywinski M. Microarray Comparative Genome Hybridization.  Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics.  John Wiley and Sons, Ltd.  July 2005

  108. Yang GS, Stott JM, Smailus D, Barber SA, Balasundaram M, Marra MA, Holt RAHigh throughput sequencing: A failure mode analysisBMC Genomics. 6:2. 2005.
  109. The Rat Genome Sequencing Project Consortium. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature.  428:475-476. 2004.
  110. Hirst M, Astell CR, Griffith M, Coughlin SM, Moksa M, Zeng T, Smailus DE, Holt RA, Jones S, Marra MA, Petric M, Krajden M, Lawrence D, Mak A, Chow R, Skowronski DM, Tweed A, Goh SH, Brunham RC, Robinson J, Bowes V, Sojonky K, Byrne SK, Li Y, Konasa D, Booth T, Paetzel M (2004).  Novel avian influenza H7N3 strain outbreak, British ColumbiaEmerging Infectious Diseases.  10:2192-2195. 2004.
  111. The MGC Project Team.  The Status, Quality and Expansion of the NIH Full-length cDNA project: the Mammalian Gene Collection (MGC)Genome Research. 14: 2093-2101. 2004.
  112. Baross A, Butterfield YSN, Coughlin SM, Zeng T, Griffith M, Griffith OL, Anca AS, Smailus DE, Khattra J, McDonald HL, McKay SJ, Moksa M, Holt RA, Marra MA.  Systematic Recovery and Analysis of Full-ORF Human cDNA Clones. GenomeResearch.14: 2083-2092. 2004. 
  113. Astell CR, Jones SJM, Holt RA, and Marra MA.  “Genome Organization and Structural Aspects of the SARS-related Virus” in Coronaviruses with Special Emphasis on First Insights Concerning SARS, Eds: Schmidt A, Wolff M and Birkhauser WO. Advances in Infectious Diseases, Ed Reche.  Birkhauser, Basel. 300pp, Vol I; 101-128. Dec 2004
  114. Warren R, Hsiao WWL, Kudo H, Myhre M, Dosanjh M, Petrescu A, Kobayashi H, Shimizu S, Miyauchi K, Masai E, Yang G, Stott JM, Schein JE, Shin H, Khattra J, Smailus D, Butterfield YS, Siddiqui A, Holt RA, Marra MA, Jones S, Mohn WW, Brinkman FSL, Fukuda M, Davies J, Eltis LD. Functional Characterization of Catabolic Plasmid from Polychlorinated-Biphenyl-Degrading Rhodococcus sp. RHA1. Journal ofBacteriology. 186;7783-7795. 2004.
  115. Mongin E, Louis C, Holt RA, Birney E and Collins FH.The Anopheles gambiae genome:  an update on sequence, data, annotation and access. Trends in Parasitology. 20: 49-52. 2003.
  116. Marra MA, Jones SJ, Astell CR, Holt RA, Brooks-Wilson A, Butterfield YS, Khattra J, Asano JK, Barber SA, Chan SY, Cloutier A, Coughlin SM, Freeman D, Girn N, Griffith OL, Leach SR, Mayo M, McDonald H, Montgomery SB, Pandoh PK, Petrescu AS, Robertson AG, Schein JE, Siddiqui A, Smailus DE, Stott JM, Yang GS, Plummer F, Andonov A, Artsob H, Bastien N, Bernard K, Booth TF, Bowness D, Czub M, Drebot M, Fernando L, Flick R, Garbutt M, Gray M, Grolla A, Jones S, Feldmann H, Meyers A, Kabani A, Li Y, Normand S, Stroher U, Tipples GA, Tyler S, Vogrig R, Ward D, Watson B, Brunham RC, Krajden M, Petric M, Skowronski DM, Upton C and Roper RL.  The Genome Sequence of the SARS-Associated CoronavirusScience. 300:1399-1404. 2003.
  117. Holt RA, Subramanian GM, Halpern A, Sutton GG, Charlab R, Nusskern DR, Wincker P, Clark AG, Ribeiro JM, Wides R, Salzberg SL, Loftus B, Yandell M, Majoros WH, Rusch DB, Lai Z, Kraft CL, Abril JF, Anthouard V, Arensburger P, Atkinson PW, Baden H, de Berardinis V, Baldwin D, Benes V, Biedler J, Blass C, Bolanos R, Boscus D, Barnstead M, Cai S, Center A, Chaturverdi K, Christophides GK, Chrystal MA, Clamp M, Cravchik A, Curwen V, Dana A, Delcher A, Dew I, Evans CA, Flanigan M, Grundschober-Freimoser A, Friedli L, Gu Z, Guan P, Guigo R, Hillenmeyer ME, Hladun SL, Hogan JR, Hong YS, Hoover J, Jaillon O, Ke Z, Kodira C, Kokoza E, Koutsos A, Letunic I, Levitsky A, Liang Y, Lin JJ, Lobo NF, Lopez JR, Malek JA, McIntosh TC, Meister S, Miller J, Mobarry C, Mongin E, Murphy SD, O'Brochta DA, Pfannkoch C, Qi R, Regier MA, Remington K, Shao H, Sharakhova MV, Sitter CD, Shetty J, Smith TJ, Strong R, Sun J, Thomasova D, Ton LQ, Topalis P, Tu Z, Unger MF, Walenz B, Wang A, Wang J, Wang M, Wang X, Woodford KJ, Wortman JR, Wu M, Yao A, Zdobnov EM, Zhang H, Zhao Q, Zhao S, Zhu SC, Zhimulev I, Coluzzi M, della Torre A, Roth CW, Louis C, Kalush F, Mural RJ, Myers EW, Adams MD, Smith HO, Broder S, Gardner MJ, Fraser CM, Birney E, Bork P, Brey PT, Venter JC, Weissenbach J, Kafatos FC, Collins FH and Hoffman SL.  The Genome Sequence of the Malaria Mosquito Anopheles gambiae. Science.  298:129-149. 2002.
  118. Zdobnov EM, von Mering C, Letunic I, Torrents D, Suyama M, Copley RR, Christophides GK, Thomasova D, Holt RA, Subramanian GM, Mueller HM, Dimopoulos G, Law JH, Wells MA, Birney E, Charlab R, Halpern AL, Kokoza E, Kraft CL, Lai Z, Lewis S, Louis C, Barillas-Mury C, Nusskern D, Rubin GM, Salzberg SL, Sutton GG, Topalis P, Wides R, Wincker P, Yandell M, Collins FH, Ribeiro J, Gelbart WM, Kafatos FC and  Bork P.  Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster. Science.  298: 149-159. 2002.
  119. Mural RJ, Adams MD, Myers EW, Smith HO,  Gabor Miklos GL, Wides R, Halpern A, Li  PW, Sutton G,  Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M and Stephenson LD).  A Comparison of Whole-Genome Shotgun-Derived Mouse Chromosome 16 and the Human GenomeScience.  296: 1661-1671. 2002.
  120. Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A and Zhu X.  The Sequence of the Human Genome. Science.  291:1304-1351. 2001.
  121. Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Sidén-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT , Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM and Venter JC).  The Genome Sequence of Drosophila melanogasterScience. 287:2185-2195. 2000.  
  122. Holt RA, Bateson AN and Martin IL.  Decreased GABA Enhancement of Benzodiazepine Binding After a Single Dose of Diazepam. Journal of Neurochemistry.  72:2219-2222. 1999. 
  123. Holt RA, Bateson AN and Martin IL.  Chronic zolpidem treatment alters GABAA receptor mRNA levels in the rat cortex. European Journal of  Pharmacology.  329:129-132. 1997. 
  124. Holt RA, Martin IL and Bateson AN.  Chronic diazepam exposure decreases transcription of the rat GABAA receptor gamma2-subunit geneMolecular Brain Research. 48:164-166. 1997.
  125. Holt RA, Bateson AN and Martin IL.  Chronic treatment with diazepam or abecarnil differently affects the expression of GABAA receptor subunit mRNAs in the rat cortexNeuropharmacology.  35(9-10):1457-1463. 1996.
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