Complete Publications of Dr. Isabella T. Tai

Isabella Tai's Complete Bibliography (Updated October 2017)
Original Peer-reviewed Articles
  1. Weiswald LB, Hasan MR, Wong JC, Pasiliao CC, Rahman M, Ren J, Yin Y, Gusscott S, Vacher S, Weng AP, Kennecke HF, Bièche I, Schaeffer DF, Yapp DT, Tai IT. Inactivation of the kinase domain of CDK10 prevents tumor growth in a preclinical model of colorectal cancer, and is accompanied by downregulation of Bcl-2. Mol Cancer Ther. 2017 Oct;16(10):2292-303.
  2. Hosseini-Beheshti E, Choi W, Weiswald LB, Kharmate G, Ghaffari M, Roshan-Moniri M, Hassona MD, Chan L, Chin MY, Tai IT, Rennie PS, Fazli L, Tomlinson Guns E. Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment. Oncotarget. 2016 Mar 22;7(12):14639-58.
  3. Wang W, Short M, Tai IT, Zeng H. Disposable sheath that facilitates endoscopic Raman spectroscopy. J Biomed Opt. 2016 Feb 1;21(2):25001.
  4. Short MA, Wang W, Tai IT, Zeng H.  Development and in vivo testing of a high frequency endoscopic Raman spectroscopy system for potential applications in the detection of early colonic neoplasia. J Biophotonics. 2016 Jan;9(1-2):44-8.
  5. Feng S, Wang W, Tai IT, Chen G, Chen R, Zeng H.  Label-free surface-enhanced Raman spectroscopy for detection of colorectal cancer and precursor lesions using blood plasma. Biomed Opt Express. 2015 Aug 24;6(9):3494-502.
  6. Neijzen R, Wong MQ, Gill N, Wang H, Karim T, Anantha M, Strutt D, Waterhouse D, Bally MB, Tai IT, Ng SS, Yapp DT.  Irinophore C™, a lipid nanoparticulate formulation of irinotecan, improves vascular function, increases the delivery of sequentially administered 5-FU in HT-29 tumors, and controls tumor growth in patient derived xenografts of colon cancer. J Control Release. 2015 Feb 10;199:72-83.
  7. Wong J, Hasan M, Rahman M, Yu A, Chan S, Schaeffer D, Kennecke H, Lim H, Owen D, Tai IT.  Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence. International Journal of Caner. 2013 Oct 1;133(7):1567-77.
  8. Mansoor H, Zeng H, Tai IT, Zhao J, Chiao M.  A Handheld Electromagnetically Actuated Fiber Optic Raster Scanner for Reflectance Confocal Imaging of Biological Tissues. IEEE Transactions on Biomedical Engineering. 2013 May;60(5):1431.
  9. Griffith M, Mwenifumbo JC, Cheung PY, Paul JE, Pugh TJ, Tang MJ, Chittaranjan S, Morin RD, Asano JK, Ally AA, Miao L, Lee A, Chan SY, Taylor G, Severson T, Hou YC, Griffith OL, Cheng GS, Novik K, Moore R, Luk M, Owen D, Brown CJ, Morin GB, Gill S, Tai IT, Marra MA.  Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.  Pharmacogenomics. 2013 Apr;13(2):148-58.
  10. Short MA, Tai IT, Owen D, Zeng H.  Using high frequency Raman spectra for colonic neoplasia detectionOptic EXPRESS. 2013 Feb 25;21(4):5025-34.  *Also featured in Virtual Journal of Biomedical Optics. 2013 Apr 4:8(3).
  11. Rahman, M, Selvarajan, K, Hasan, MR, Chan, AP, Jin, C, Kim, J, Chan, SK, Le, ND, Kim, YB, Tai, IT.  Inhibition of COX-2 in Colon Cancer Modulates Tumor Growth and MDR-1 Expression to Enhance Tumor Regression in Therapy-Refractory Cancers In Vivo. Neoplasia. 2012 July 14(7): 624-33.
  12. Jones N, Chiba N, Fallone C, Thompson A, Hunt R, Jacobson K, Goodman K, Tai IT (Canadian Helicobacter Study Group Participants-22 in total).  Helicobacter pylori in First Nations and recent immigrant populations in Canada. The Canadian Journal of Gastroenterology. 2012 Feb;26(2):97-103.
  13. Rahman M, Chan AP, Tang MJ, Tai IT. A peptide of SPARC interferes with the interaction between Caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivo.  PLoS One.2011;6(11):e26390.
  14. Hasan MR, Ho SHY, Owen D, Tai IT. VEGF inhibitors induce cellular senescence in colorectal cancer cells. International Journal of Cancer.2011 Nov 1;129(9):2115-23.
  15. Wong JC, Chan SK, Schaeffer DF, Sagaert X, Lim H, Kennecke H, Owen D, Suh KW, Kim Y-B, Tai IT. Absence of MMP2 expression correlates with poor clinical outcomes in rectal cancer, and is distinct from MMP1-related outcomes in colon cancer. Clinical Cancer Research.2011 Jun 15; 17(12):4167-76.
  16. Griffith M, Griffith OL, Mwenifumbo J, Goya R, Morrissy AS, Morin RD, Corbett R, Tang MJ, Hou Y-C, Pugh TJ, Robertson G, Chittaranjan S, Ally A, Asano JK, CHan SY, Li HI, McDonald H, Teague K, Zhao Y, Zeng T, Delaney A, Hirst M, Morin GB, JOnes SJM Tai IT, Marra MA. Alternative expression analysis by RNA sequencing. Nature Methods.2010 Oct; 7(10):843-7.
  17. Crispo JA, Piché M, Ansell DR, Eibl JK, Tai IT, Kumar A, Ross GM, Tai TC. Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells. Biochemical Biophyssical Research Communication.2010 Mar 19;393(4):773-8.
  18. Chan JH, Ho S, Tai IT. Secreted protein acidic and rich in cysteine-induced cellular senescence in colorectal cancers in response to irinotecan is mediated by p53. Carcinogenesis.2010 May;31(5):812-9.
  19. Khan MA, Steiner Ts, Sham HP, Bergstrom KS, Huang JT, Assi K, Salh B, Tai IT, Li X, Vallance BA. The Single IgGIL-1-Related Receptor Controls TLR Responses in Differentiated Human Intestinal epithelial cells. Journal of Immunology.2010 Mar 1;184(5):2305-13.
  20. Tai, IT, Tang, MJ. SPARC in cancer biology: its role in cancer progression and potential for therapy. Drug Resistance Updates.2008 Dec; 11(6):231-46. [Epub 2008 Oct 11].
  21. Cheetham S, Tang MJ, Mesak F, Kennecke H, Owen D, Tai IT. SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response. British Journal of Cancer. 2008 Jun 3;98(11):1810-9. [Epub 2008 May 6.]
  22. Chan SK, Griffith OL, Tai IT, and Jones SJM. Meta-analysis of Colorectal Cancer Gene Expression Profiling Studies Identifies Consistently Reported Candidate Biomarkers. Cancer Epidemiololy Biomarkers and Prevention.2008;17(3):543-52.
  23. Griffith M, Tang MJ, Griffith OL, Chan S, Asano J, Zeng T, Flibotte S, Ally A, Baross A, Morin RD, Hirst M, Morin G, Jones SJM, Tai IT and Marra MA. ALEXA – An array design platform for alternative expression analysis. Nature Methods.2008 Feb;5(2):118.
  24. Tang MJ, Tai IT. A novel interaction between procaspase 8 and SPARC enhances apoptosis and potentiates chemotherapy sensitivity in colorectal cancers. Journal of Biological Chemistry.2007 Nov 23;282(47):34457-67. [Epub 2007 Sep 26].
  25. Taghizadeh F, Tang MJ, Tai IT. Synergism between vitamin D and SPARC-induced apoptosis and inhibition of cell growth results in increased susceptibility of therapy-resistant colon cancer cells to chemotherapy. Molecular Cancer Therapeutics. 2007 Jan;6(1):309-17.
  26. Tai IT, Dai M, Owen DA and Chen LB. Genome-wide expression analysis of therapy resistant tumors reveals SPARC as a novel target for cancer therapy. Journal of Clinical Investigation.2005; 115(6):1492-1502.
  27. Tai IT, Dai M and Chen LB. Periostin induction in tumor cell line explants and inhibition of in-vitro cultured cell growth by anti-periostin antibodies. Carcinogenesis.2005; 26(5):908-15.
  28. Davies FE, Dring AM, Li C, Rawstron AC, Shammas MA, O’Connor SM, Fenton JA, Hideshima T, Chauhan D, Tai IT , Robinson E, Auclair D, Rees K, Gonzalez-Castro D, Ashcroft AJ, Dasgupta R, Mitsiades C, Mitsiades N, Chen LB, Wong WH, Munshi NC, Morgan GJ, Anderson KC. Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis. Blood.2003 Dec 15;102(13):4504-11.
  29. Tai IT, Vacek I and Sun AM. The alginate-po1y-L-lysine-alginate membrane: Evidence of a protective effect on microencapsulated islets of Langerhans following exposure to cytokines. Xenotransplantation1995; 2:37-45.
  30. Tai IT and Sun AM. The microencapsulation of recombinant cells: a new delivery system for gene therapy. FASEB Journal.1993; 7:1061-1069.
  31. Krestow M, Lum P, Tai IT , and Sun AM. Free versus microencapsulated pancreatic islet xenografis producing amelioration of streptozotocin toxicity. Biomaterials, Artificial Cells, & Immobilization Biotechnology. 1992; 20:43-51.
  32. Lum ZP, Krestow M, Tai IT , Vacek I, and Sun AM. Xenografts of rat islets into diabetic mice -an evaluation of new smaller capsules. Transplantation.1992; 53:1180-1183.
  33. Krestow M, Lum ZP, Tai IT , and Sun AM. Xenotransplantation of microencapsulated fetal rat islets. Transplantation.1991; 51:651-655.
  34. Lum ZP, Tai IT , Krestow M, Norton J, Vacek I, and Sun AM. Prolonged reversal of the diabetic state in NOD mice by xenografis of microencapsulated rat islets. Diabetes.1991 Nov;40(11):1511-6.
  35. Fan MY, Lum ZP, Fu X, Levesque L, Tai IT , and Sun AM. Reversal of diabetes in BB-rats by transplantation of encapsulated pancreatic islets. Diabetes.1990 Apr;39(4):519-22.
Original Peer Reviewed Clinical Articles
  1. Chung C, Al Ali J, Owen DA, Weiss AA, Yoshida EM, Tai IT. A rare case of isolated duodenal metastases from hepatocellular carcinoma associated with p53 and ki-67 expression: a case report. Cases Journal. 2009 Dec 17;2:9344
Non-peer Reviewed Articles
  1. Tai IT. Developing a clinician-scientist career.  Clin Invest Med. 2008 Oct 1;31(5):E300-1.
Book Chapters
  1. Greenberg GR and Tai IT. Inflammatory Disease in the elderly. In: Trends in Inflammatory Bowel Disease Therapy. Eds. CN Williams. Dordrecht, London: Kluwer, 2000.
  2. Sun AM, Vacek I, Tai IT. Chapter 18: Microencapsulation of living cells and tissues. In: Microcapsules and Nanoparticles in Medicine and Pharmacy. CRC Press, Inc., Florida. 1992.
Page last modified Oct 13, 2017