Review of Massively Parallel MicroRNA Profiling in Cancer
This chapter is a review of the new sequencing technologies allowing measurement of microRNA and mRNA expression (miRNA-seq and RNA-seq) while also enabling discovery of polymorphisms, mutations and RNA edits. We discuss the relevance of microRNAs in various cancers with a focus on B-cell malignancies. It will be featured as Chapter 3 in an upcoming book entitled "microRNA Profiling in Cancer: A Bioinformatics Perspective"
Morin RD, Zhao YJ, Prabhu AL, McDonald H, Dhalla N, Thorne C, Pandoh P, Tam A, Zeng T, Hirst M, Marra MA. Preparation and analysis of microRNA libraries using the Illumina massively parallel sequencing technology. In: MicroRNA Profiling in Cancer: A Bioinformatics Perspective. editor Yuriy Gusev (University of Oklahoma, USA), World Scientific Books, ISBN: 978-981-4267-01-4 In press. 2009