ChIP-seq for STAT1 in HeLa cells
This work demonstrated a new technique for detecting where proteins that control gene expression are bound to DNA, and the manuscript showed that the new technique was accurate. Such technology will be key in furthering our understanding of the complex genetic networks that are activated during the progression of cancer.
Robertson G, Hirst M, Bainbridge M, Bilenky M, Zhao Y, Zeng T, Euskirchen G, Bernier B, Varhol R, Delaney A, Thiessen N, Griffith OL, He A, Marra M, Snyder M, Jones S. Nature Methods 2007. 4(8):651-657.
Further details of this publication can be found online ate:http://www.ncbi.nlm.nih.gov/pubmed/17558387?ordinalpos=4
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