FASSI 0.1 released
We have developed a targeted approach to improve the contiguity of whole-genome shotgun sequence (WGS) assemblies at run-time, using information from Bacterial Artificial Chromosome (BAC)-based physical maps. Clone sizes and overlaps derived from clone fingerprints are used for the calculation of length constraints between any two BAC neighbors sharing a significant portion of their size. These constraints are used to promote the linkage and guide the arrangement of sequence contigs within a scaffold at the layout phase of WGS assemblies. This process is facilitated by FASSI, the fingerprint and assembly incorporation software. For more information, visit the FASSI software page.